
Boutique hotels in Key West
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Top-rated boutique hotels in Key West
Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

Conch Key Villas #2 Peaceful waterfront lodging
Studio Two's waterfront rental is located on the ground level. Each unit comes with a boat slip and parking for your trailer. We can handle boats up to 25’. There is a boat ramp just 2 blocks away. We provide outside table and chairs, and just around the corner, the barbecue grill. Our accommodations include king bed, living and dining area, futon, polished terrazzo floors, waterfront patio, literally 6 feet from the water, full size and equipped kitchens, A/C and cable TV, DVD and Wi-Fi.

Marrero's Guest Mansion Adult Only (21+) Room 12
Adult Only Boutique Hotel (21+). Experience the grandeur of their stately Victorian home, thoughtfully updated and lovingly converted into a boutique hotel. We are located in the heart of Old Town, just half a block from Duval Street. This beautiful room is right next to our revitalizing saltwater-treated pool. Separate from the main house, this cabana room offers guests a more private tropical escape. This room features a pillow top king bed with a private bath and sitting area.

Conch Key Villas #1. Fun, fishing & great sunsets
Studio One's waterfront rental is located on the ground level. Our units differ vastly from other Florida Keys lodgings because our property is right on Florida Bay. If you trailer your boat, the dockage is a few feet from the back door. Our docks can handle boats up to 25’ and you can park your trailer in our front lot. There is a boat ramp just two blocks away. Studio 1 can sleep 2 adults and one child (up to 12 years). We have a king size bed and a futon.

Marrero's Guest Mansion Adult Only (21+) Room 10
Adult Only (21+) Boutique Hotel. Experience the grandeur of the stately Victorian home, thoughtfully updated and lovingly converted into a boutique hotel. Our location in the heart of Old Town in Key West, just half a block from Duval Street. This charming room is as welcoming as the friendly island locals and features a pillow top queen bed and full private bath. Its private second floor veranda overlooks the garden and pool areas at the back of the house.

Mallory House Room #3
There is no better place for your Key West stay than Mallory House. This historic circa 1890’s home is located on Duval Street in the Gato Cigar Factory Village. Mallory House is steps away from famous attractions, restaurants, cafés, bars and shops. Stay within close proximity to the Southernmost point and beach, the Hemingway house and lighthouse. Enjoy a complimentary cup of coffee on our spacious balcony overlooking world famous Duval Street.

Marathon Oceanfront Suite | King Bed + Kitchenette
Escape to the Oceanfront Balcony | 1BR King (Suite), where breathtaking ocean views and luxury amenities await. This spacious suite features a plush king bed, a separate living area with a queen sofa bed, a kitchenette, and a spa-like bath with a walk-in rainfall shower. Step onto your private oceanview terrace, and experience five pools, beachfront dining, and endless coastal adventures in the Florida Keys.

Wreckers House King Room - Adults Only
Adults-only building for guests ages 21+ only. Thoughtfully furnished with mixed metals and woods, the Wreckers House tells the story of ships and their crews of "wreckers" who once salvaged goods from the sunken ships in the Florida Keys. Enjoy a sunrise view and an ocean breeze from your private balcony that overlooks the pool and the Atlantic. This room has a mini fridge and an espresso machine.

Family Room in Duck Key | Sauna, Kayak & Pools
Gather the crew in the Family Oasis—a bright, roomy hideaway where bunk beds delight the kids and a plush king bed welcomes parents. Ideal for up to five guests, this relaxing space blends laid-back comfort with family-ready convenience. Located in Hawks Cay Resort, enjoy a full day of waterside fun, unwind in your oversized room, and let island time set the pace for your unforgettable stay.

Cabana Inn Private Loft In Old Town with Breakfast
When tropical oasis meets Duval Street, you know you have arrived at the Cabana Inn. Located just a block from Duval Street, our adult-only Key West inn is hidden amongst the shady trees to create a tranquil paradise. The historic conch estate, with cottages that were meticulously converted into a comfortable Key West hotel, features modern designs throughout the interior and exterior.

Parrot Key, Garden 2 Bedroom Suite w/ Living Room
The island life awaits you at the Parrot Key Hotel and Villa in Key West. The Island getaway has an authentic ambiance with locally-inspired rooms and views of the Gulf of Mexico. Your room charge will be paid prior to your arrival. The remaining balance of taxes (12.5%) and facility fee ($51 resort fee + 12.5% tax + $30 valet fee) will be charged upon arrival.

Marrero's Guest Mansion Adult Only (21+) Room 11
Adult Only Boutique Hotel (21+). Experience the grandeur of their stately Victorian home, thoughtfully updated and lovingly converted into a boutique hotel. We are located in the heart of Old Town, just half a block from Duval Street. This lovely room at the top of the stairs features a pillow top queen bed, private bath, sitting area, and a private balcony.

NYAH 6 Person Room w/ Private Balcony & Breakfast
True Floridian vibe accentuated by a unique, adult-only concept, only steps from world-famous Duval Street, the head-turning Gulf, and countless eateries and shops. Our guests will quickly discover three crystal-clear pools, a Jacuzzi, a small fleet of bicycle rentals, high-speed Wi-Fi, a continental breakfast bar, and free 24-hour Starbucks coffee.
Popular amenities for Key West boutique hotels
Family-friendly boutique hotels

Poolside Room w/ Spa & Tiki Beach | No Hidden Fee

Humidor House King Room - Adults Only

Conch House 3 Bedroom Suite at Grassy Flats Resort

ADA Room w/ Views, Spa & Water Fun | No Hidden Fee

Two Bedroom Suite

Deluxe King

Cozy Queen Rm in Duck Key | Sauna & Snorkeling

Partial Water View Two Bedroom Suite w/Living Room
Boutique hotels with a patio

Conch Key Villas #1. Fun, fishing & great sunsets

Conch Key Villas #2 Peaceful waterfront lodging

Marrero's Guest Mansion Adult Only (21+) Room 11

Marrero's Guest Mansion Adult Only (21+) Room 10

Wreckers House Double Queen Room - Adults Only

Historic Cigar Barons Mansion

Galleon King Suite - Adults Only
Other boutique hotel vacation rentals

Poolside Room w/ Kayak & Sauna | No Hidden Fee!

King ADA w/ Views in Duck Key | Marina, Spa & Pool

Perfect for a Relaxing Getaway w/ Free Breakfast

Boutique Hotel w/ Pool Access, Free Breakfast!

Partial Water View Villa 3 Queens, 1 King Bed

Dbl Queen Room | Pool, Spa & Kayak | No Hidden Fee

Water View King Rm in Duck Key | Spa, Kayak & Pool

Duck Key Trip! | ADA Family Rm w/ Snorkeling + Spa
When is the best time to visit Key West?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$124,463 GYD | G$138,059 GYD | G$123,208 GYD | G$70,912 GYD | G$80,953 GYD | G$60,453 GYD | G$63,173 GYD | G$51,877 GYD | G$45,183 GYD | G$52,923 GYD | G$73,213 GYD | G$78,861 GYD |
| Avg. temp | 21°C | 22°C | 24°C | 25°C | 27°C | 29°C | 30°C | 30°C | 29°C | 27°C | 25°C | 23°C |
Quick stats about boutique hotels in Key West

Total vacation rentals
Explore 40 vacation rentals in Key West

Nightly prices starting at
Key West vacation rentals start at G$29,285 GYD per night before taxes and fees

Verified guest reviews
Over 2,200 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Vacation rentals with a pool
30 properties feature pools

Wi-Fi availability
30 of Key West vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Key West rentals

4.6 Average rating
Key West stays receive an average rating of 4.6 out of 5 from guests
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