House vacation rentals in Isla Grande

4.97 out of 5 average rating, 103 reviews

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

4.95 out of 5 average rating, 60 reviews

Home in Panamá

Cozy cabin in nature with garden in Cerro Azul

Disfrute de la naturaleza y un clima agradable, alejado del ruido y el calor de la ciudad en esta espaciosa y hermosa cabaña, decorada con detalles de madera que dan una sensación de calidez increíble. En ella encontrará WIFI, TV y Netflix incluido. A solo 50 minutos de la ciudad, es el lugar perfecto para viajar con familia y amigos. Además para familias viajando con niños pequeños, le ofrecemos play y silla de comer. Escríbanos para cualquier duda y estaremos siempre disponible para ayudarle.

4.75 out of 5 average rating, 8 reviews

Home in Panamá

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

Come and relax with the entire family at this peaceful, private and and safe property. Surrounded by a tropical rain forest and comfortable temperature. A home away from home is on the 2nd level with walk out to the pool. Waterfalls, rivers, trails and more to explore in the safe community. Cook your own food, have us cook for you or a restaurant next door. Private 2 and a 1/2 bathrooms, kitchen and dining in bohio overlooking the pool, internet and cable TV. Free parking for 3 vehicles.

Home in Santa Rita Arriba

5 out of 5 average rating, 3 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain, birds, and our chickens. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. Please read description fully.

Top guest favorite

Home in Juan Gallego

4.95 out of 5 average rating, 37 reviews

Kasa Leilani - the perfect getaway!

Welcome to Kasa Leilani, a charming beach house nestled between the jungle and the reef in the heart of a natural park. With stunning views of the nearby Caribbean islands, this peaceful retreat offers the perfect blend of nature and comfort. Surrounded by abundant wildlife, you can relax, explore the reef, or discover the island and crystal-clear waters. Kasa Leilani provides a serene escape for nature lovers and beach enthusiasts alike, offering an unforgettable tropical getaway.

4.95 out of 5 average rating, 19 reviews

Home in Colón

Family Style Living, in Colon #3

Relax with the whole family at this peaceful place. This house is located on reverted Areas transferred back to Panamá, called Arco Iris, there’s plenty of space outside, the inside consist of a modern combination living room+kitchen, bathroom and a large bedroom with acomodación for 4 guest, the place is Airconditioned with Celling fans in the living room and bedroom. This is a third house constructed next to our first rental called, Family Style Living and close to the Panamá Canal

4.81 out of 5 average rating, 31 reviews

Bella Casa, Caribbean Sea, Juan Gallego (waterfront)

Hermosa Casa de Playa, frente al mar caribe, para descansar y relajarse al 100%. La Casa cuenta con una ubicación privilegiada, mantiene 4 habitaciones (una de ellas cuenta con una mampara para dividir de la sala y ampliar esa área en caso que se desee), sala, comedor, terraza privada, frente a Isla Grande. 3 habitaciones tienen TV con cable y una TV extra en la sala. Todas con con Aire Acondicionado. Cuenta con 2 baños completos. Cocina equipada y lista para disfrutar y Wifi

4.75 out of 5 average rating, 8 reviews

Beautiful oceanfront country house

Casa de Campo facing the sea in the form of a boat.. where you can see, hear and hear the sounds of the sea of birds and nature. It has 4 alcoves with AA of which the main one has a delicious balcony overlooking the sea It is a nice place where you can enjoy hiking, fishing, boating, horseback riding, bathing in waterfalls, rivers and much more! The house is wooden and we design it as if it were an experience inside a boat, it is an ideal place to rest

Top guest favorite

Home in Panamá

4.94 out of 5 average rating, 52 reviews

Majestic Villa in the Mountains

Relax with the whole family at this peaceful place to stay. The majestic Villa Lola is a special place located in an exclusive residential area, with 24-hour security, Los Altos de Cerro Azul. A place within Chagres National Park surrounded by rivers, lakes, waterfalls, trails and endless wildlife species, where you can experience a different adventure every day. Located 55 minutes from the city and 30 minutes from Tocumen International Airport :)

5 out of 5 average rating, 4 reviews

Home in Cacique

House in Cacique- Jungle and Sea

Finca Cacique offers a peaceful jungle escape just 5 minutes by foot from Cacique beach. This 4-bedroom house (3 with A/C, 1 with fan) is surrounded by nature and visited by monkeys, sloths, and birds. We have 2 kayaks for rent to explore nearby islands such as Isla Mamey and the Tunnel of Love. Enjoy the jungle’s beauty with the sea nearby. (Note: not beachfront property.) Perfect for nature lovers seeking tranquility and adventure.

4.96 out of 5 average rating, 23 reviews

Home in Cacique

El Paraiso

We are pleased to present a large beautiful house for rent between the village of Cacique and the village of José Pobre in Portobelo National Park. Overlooking the Caribbean Sea, nestled in the jungle, this house has a unique character in the area. Its direct access to a small wild beach, with an exciting reef for snorkeling fans, makes it a privileged place. Ideal for groups and families wishing to reconnect with nature.