
House vacation rentals in Isla Grande
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Top-rated house rentals in Isla Grande
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The Bird's Nest in the Clouds
Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Beachfront House in Isla Grande Province of Colon
Ven a relajarte en esta hermosa y acogedora casa frente al mar, situada en una isla mágica donde la gastronomía es exquisita con una gran variedad de mariscos y de sus playas encantadoras de aguas cristalinas y arena blanca. Hay una gran variedad de actividades por hacer y toda una cultura costera por conocer: Desde los bailes folclóricos (congo) hasta su hermoso pueblo de tez morena. No olvides preguntarnos de los toures turísticos disponibles a las islas cercanas, ¡No te arrepentirás!

Family style living in Colon, #2
Relax with the whole family at this peaceful place. This house is located on reverted Areas transferred back to Panamá, called Arco Iris, there’s plenty of space outside, the inside consist of a modern combination living room+kitchen, bathroom and a large bedroom with acomodación for 4 guest, the place is Airconditioned with Celling fans in the living room and bedroom. This is a second house constructed next to our first rental called, Family Style Living and close to the Panamá Canal Zone

Beachfront · Large Sea View · Family Friendly
Welcome to Kasa Leilani, a charming beach house nestled between the jungle and the reef in the heart of a natural park. With stunning views of the nearby Caribbean islands, this peaceful retreat offers the perfect blend of nature and comfort. Surrounded by abundant wildlife, you can relax, explore the reef, or discover the island and crystal-clear waters. Kasa Leilani provides a serene escape for nature lovers and beach enthusiasts alike, offering an unforgettable tropical getaway.

Casa Dinis, Studio, Downtown Portobelo
Relax! You're in the Caribbean! The Studio is in the historic center of Portobelo, a World Heritage town. You have the opportunity to live a real experience and share with a town full of history, cultural identity and beautiful people! The Studio is on the ground floor of Casa Dinis and has a separate entrance, a queen size bed and a sofa bed (preferably for children). The space is very comfortable, equipped kitchen, bathroom, air conditioning, Internet and TV Welcome!

Villa with Private Terrace in Playa Escondida
**El apartamento** Planta Baja con terraza privada y la playa está a solo unos pasos ! Nuestra villa es una de las opciones más accesibles para familias con niños y adultos mayores !! >>>>podras llegar a la playa y a las piscinas sin preocuparte por subir escaleras ni usar elevadores <<<< *Amenidades del Resort* -Gimnasio -Kayak, botes de remo, Bohío con BBQ (reserva previa) -Restaurantes -Cancha de fútbol, pádel y volleyball -Parque acuático -Tiendita

House in Cacique- Jungle and Sea
Finca Cacique offers a peaceful jungle escape just 5 minutes by foot from Cacique beach. This 4-bedroom house (3 with A/C, 1 with fan) is surrounded by nature and visited by monkeys, sloths, and birds. We have 2 kayaks for rent to explore nearby islands such as Isla Mamey and the Tunnel of Love. Enjoy the jungle’s beauty with the sea nearby. (Note: not beachfront property.) Perfect for nature lovers seeking tranquility and adventure.

Beach house, facing the sea!
Experience total calm in our Oceanfront House, an ideal family retreat, where you will feel relaxed and experience the tranquility you dream of. You will have the sea 24 hours a day, you can hear the waves and the sea breeze everywhere. Whether you're relaxing on the terrace, reading a good book, or watching the beautiful sunsets of La Guaira in Colón, this space reconnects you with yourself and nature. Ideal for families

El Paraiso
We are pleased to present a large beautiful house for rent between the village of Cacique and the village of José Pobre in Portobelo National Park. Overlooking the Caribbean Sea, nestled in the jungle, this house has a unique character in the area. Its direct access to a small wild beach, with an exciting reef for snorkeling fans, makes it a privileged place. Ideal for groups and families wishing to reconnect with nature.

Casa del Lago 2025
New lakefront house in Cerro Azul, decorated by a D&G architect with furniture brought from Bali. It has 3 bedrooms, 3 bathrooms and 4 double beds, equipped kitchen, BBQ, air conditioning and hot water. Cook a delicious BBQ with your friends in front of the lake and enjoy the sunsets from an unparalleled view with direct access and kayak included.

Sparrow's Point
Un lugar paradisiaco que muestra al caribe panameño en su mejor esplendor!! La playa de arena blanca protegida por una bahía de aguas cristalinas y enmarcada por la selva tropical crean un idílico contraste entre el verde del follaje y el azul de la laguna. Despierte a 10 pasos del mar.

Villa Las Valentinas @ Cerro Azul
Make some memories at this unique and family-friendly place. Surround yourself with the nature that Cerro Azul near Panama City offers you. An ideal place to spend time with your family and pets!
Popular amenities for Isla Grande house rentals
House rentals with a pool

Casa Amarilla

Lagoon & Oceanfront Retreat · Infinity Pool

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

House facing Isla Grande

“Beautiful and Comfortable Villa in Playa Escondida”

Your country house, Menus de la Montaña, awaits you.

Carmen's House

Home On The Lake Cerro Azul
Weekly house rentals

Your oceanfront paradise

Casa la Perfecta, Big Island, Oceanfront

House with spectacular city and ocean views

Casa Chalis

Oceanfront beach house. La Guaira, Colón

NEW House+AC+Kitchen+BBQ+Pool+Sea View @IslaGrande

Clean family style lakehouse

OCEAN FRONT HOUSE AT THE CARIBBEAN - Pets allowed
Private house rentals

Fresh air and a cozy atmosphere!

Cabaña para 2 personas.

Beach house on Isla Grande

Casa con la única piscina privada en la isla

Beachfront Property in Palenque - Paradise!

Beautiful oceanfront country house

Relax in Cerro Azul

Naturlove wildlive tranquility Paradise Lakeshore
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