
Guesthouse vacation rentals in Greenville
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Top-rated guesthouse rentals in Greenville
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

The Spring Valley Retreat
Newly renovated in 2021, very comfortable guesthouse located in a quiet neighborhood just 10 minutes from downtown Greenville. Created by highly experienced bed and breakfast owners, this space is carefully crafted to be a relaxing, restful place for travelers. Two bedrooms, a kitchen with brand-new appliances, dining area, smart TV, a desktop space, WiFi, and an outdoor porch spot to enjoy nice weather days. Note that if you search the address on Google, it will pull up photos before renovation

Historic 19th Century Cabin/Guest House
This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.

Nishleigh's Nook - West End Downtown Greenville
Welcome to your cozy retreat in the West End of Downtown Greenville! This newly constructed, detached garage studio near the up and coming West End Village, Unity Park, and downtown offers easy access to the city's best entertainment, boutique shops, and vibrant food scene. Enjoy a queen-sized memory foam bed, a fully equipped kitchen, and a dedicated dining area. High-speed Wi-Fi and a smart TV are included. Perfect for a peaceful escape with all the comforts you need for a memorable stay.

The Cottage at Old Oaks Farm
Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

Gorgeous Downtown Studio & Dog Friendly!
This has moved to 30 days+ starting Jan 2024! Message me if you're trying to book and your dates aren't showing available! This location is unmatched. Steps from Falls Park which includes one of the most majestic waterfalls, green space and Swamp Rabbit Trail for all your running/walking and biking needs. Directly across the street from the Greenville Drive baseball stadium. One block from all the finest restaurants, shopping and best attractions downtown offers.

Family & Pet-Friendly Retreat near Bridgeway & DT
Enjoy a private, pet-friendly retreat in a peaceful neighborhood, featuring a fenced yard, cozy fire pit, and relaxing outdoor lounge perfect for unwinding after a long day. Ideally located just minutes from Bridgeway Station, Downtown Greenville, restaurants, shops, and daily essentials. Perfect for couples, small families, remote workers, or weekend escapes, offering comfort, privacy, and convenience in one charming stay designed to make you feel right at home.

Greenville With A View!
ONLY 10-15 MINUTE DRIVE TO THE HEART OF BEAUTIFUL DOWNTOWN GREENVILLE! We are only 11 miles to GSP Airport; 6 miles to Greenville Downtown Airport; and 10 minutes to the Swamp Rabbit Trail. We are minutes to Furman University, Bob Jones University, North Greenville University and Clemson University is only 45 minutes away. We are tucked away open top of Paris Mountain. If you want to bike, hike, paddle, swim, boat or just soak it all in, start here!

Private Suite in Downtown Simpsonville
Cozy 1 bed/1 bath apartment in downtown Simpsonville. With this private single unit above a garage used for storage only, you do not share walls with anyone! You are within walking distance to restaurants & shopping! This private unit is a rare find for the price!! As you pull into your own parking space, you overlook a private yard. ***Please note there is a train near the home that runs once midday and once late at night.

Foothills Favorite
Custom designed 1 bedroom suite in the Lake Bowen/Landrum/Inman area. Comfortable yet sleek space tucked above a semi-detached garage; private entry & stairway to suite. Private deck overlooks green spaces, wooded area & Lake Bowen (best views late fall and winter). Enjoy mountain views at nearby Lake Bowen park, local wineries, and scenic highways. Minutes from Landrum & Tryon & Equestrian Center.

Shou-Sugi-Ban Retreat on the Saluda River
The Shou-Sugi-Ban Guest House is 5 miles from Greenville city center and West Greenville, yet you'll feel like you've escaped it all with the rush of the river and surrounding trees. This cozy, custom space has a king-size bed, and two sets of French doors leading out to a private deck. No matter where you are in the space, you'll have views of the 700 ft of Saluda river frontage.

Sally's Cottage
Couples retreat located 6 miles from downtown Greenville and the Swamp Rabbit Trail in a comfortable country setting. Wake up to a beautiful woods view through a large bay window and wildlife that surrounds the cottage (deer, birds and squirrels). Experience the beauty of the country in the city! Enjoy the eclectic collection of art and design in this cute little cottage.

Modern guesthouse in downtown TR
Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more! Enjoy a stylish, relaxed stay at our centrally-located place. Whether you're an outdoor enthusiast or fun-loving foodie, you'll find something just for you nearby. Only a short drive to downtown Greenville, Furman University or Paris Mountain. Within an hour drive of Asheville and Clemson University!
Popular amenities for Greenville guesthouse rentals
Family-friendly guest house rentals

Cowboy Cottage 8 miles to TIEC

Country-Clubhouse Tiny Home. Close to downtown!

Cozy Pool House

Fairy Forest Cabin with Hot Tub at Table Rock

Renewal Rock

Quiet Guest Apartment in the Woods

Cozy faux-cabin loft by GSP, BMW

1 bedroom guest house on horse property in Tryon
Guest house rentals with a patio

Guest Cottage with Private Drive

Clean. Comfortable. Convenient.

The Dwelling Place: Just a mile from downtown TR

The Travelers’ Rest

Chic Studio with Private Deck

11-Acre work retreat — fast Wi-Fi + peaceful stay

Sugar Creek Retreat

2BR Guesthouse Retreat Near Furman w/ Pond Views
Guest house rentals with a washer and dryer

Quiet King Two Bedrm House

Upscale cottage in Downtown Fountain Inn

Bungalow on a 3 acre mini farm

The oaks cottage

Cozy Above Garage Apartment on Paris Mountain

Cozy 1 BR Cottage - Great Location!

Just off Main near Taylors Mill - Clean & Comfy

Adorable renovated private house w/ parking.
When is the best time to visit Greenville?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$19,426 GYD | G$20,889 GYD | G$20,262 GYD | G$20,053 GYD | G$19,844 GYD | G$20,471 GYD | G$21,306 GYD | G$21,515 GYD | G$20,889 GYD | G$20,889 GYD | G$20,889 GYD | G$20,471 GYD |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 20°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Quick stats about guesthouse rentals in Greenville

Total vacation rentals
Explore 30 vacation rentals in Greenville

Nightly prices starting at
Greenville vacation rentals start at G$10,444 GYD per night before taxes and fees

Verified guest reviews
Over 3,860 verified reviews to help you choose

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
30 of Greenville vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Greenville rentals

4.9 Average rating
Greenville stays are highly rated by guests—averaging 4.9 out of 5!
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- Blue Ridge Parkway
- The North Carolina Arboretum
- Gorges State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Table Rock State Park
- Lake Lure Beach and Water Park
- Clemson University
- Jump Off Rock
- Tryon International Equestrian Center
- Biltmore House
- Carl Sandburg Home National Historic Site
- Saint Paul Mountain Vineyards
- Bon Secours Wellness Arena
- Burntshirt Vineyards
- Overmountain Vineyards
- DuPont State Forest
- Falls Park On The Reedy
- Devils Fork State Park
- Jones Gap State Park
- Peace Center
- Chattooga Belle Farm
- Blue Ridge Parkway Visitor Center
- Fred W Symmes Chapel




