House vacation rentals in Greenville

A Tranquil Place (near downtown Greenville)

A Tranquil Space is conveniently located close to Downtown Greenville. The large suite includes the bedroom, living area, kitchenette (fridge/freezer/convection oven), bathroom, and study/eating area. It is newly renovated area on the end of my home with a private entrance. The space is welcoming and inviting...a perfect space to get away from the hustle. Although minutes from Downtown, the suite feels like you're in the mountains with a private back yard and many trees. Enjoy your stay!

Fenced in Yard, 2 Queen Beds, Downtown!

Hard to beat this amazing value! Nestled on a quiet street 5 minutes from downtown, this 2bed/1bath property is perfect for your visit to Greenville. Each bedroom has a queen bed and plenty of closet space with hangers. Out back, there's a spacious deck to relax on, and the property has a fenced in yard which would be ideal for your curious furry friend. This property is minutes from hospitals & interstate 85. Ideal for work travelers, or simply curious visitors. There's a driveway for parking.

Greenville GEM Luxurious Retreat in Prime Location

Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating.  Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Downtown Gem-Walk to Park-Bon Secours-Shops

Come enjoy this cozy unit centrally located in the Pettigru Historic District just a stones throw from downtown (15 minute walk) and 5 minute walk to Bon Secours Wellness Arena. This is a unit within a renovated historic triplex and has it's own, private, exterior entry. Inside is renovated and has a kitchen that has all the items you need for your stay (utensils, pots, pans, cups, bowls, etc.) as well a stocked Nespresso machine! Please note the bathroom is not suitable for guests over 6'.

Spectacular home 1 mile from Main St Greenville!

Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Pet-Friendly 2BR • Fenced Yard Near Downtown GVL

Located in Greenville’s Historic Dunean District, this cozy 2BR home is less than 10 minutes to Downtown Greenville, Unity Park, Falls Park, and the Swamp Rabbit Trail. Enjoy a pet-friendly stay with a fully fenced backyard, enclosed sunroom with hammock, garden views, and high-speed fiber WiFi. This is an allergy-friendly, fragrance-free home using only non-toxic cleaning and laundry products—no scented candles or air fresheners. Nestled in a quiet, safe neighborhood close to restaurants.

West Village Modern Sanctuary

Step outside your private abode and explore the Swamp Rabbit Trail, a scenic greenway perfect for biking, or a quick drive to downtown's main attractions. Immerse yourself in the artistic energy of the West End Village's galleries, or try delicious local restaurants, coffee shops, and bakeries. This charming retreat offers the perfect blend of comfort, convenience, and purposeful style, ideal for families, friends, or remote workers seeking an authentic Greenville experience.

Quaint Downtown Greenville Home

Tucked away in a quaint little Downtown Greenville neighborhood, this 2 bed 1 bath home is sure to provide a stylish and comfortable retreat. You'll find a stylish professionally designed interior, fully equipped kitchen, free wifi and netflix, and laundry machines. Hang out on the back deck or front porch, or walk/drive over to Cleveland Park, the Greenville Zoo, Willy Taco (amongst many other award winning restaurants close by, or Main St itself. We'd love to have you!

Stylish 3BR Home: Pet-Friendly, Outdoor Lounge

Welcome to Chardonnay Chateau, a stylish 3 bedroom, 2 bathroom home just 3 miles from Downtown Greenville. We are conveniently located next to: Shops at Cherrydale (0.7 mi) Downtown Greenville (3.5 mi) Bon Secours Wellness Arena (3.5 mi) Downtown Traveler's Rest (7 mi) Our home provides ample space to enjoy with your loved ones, including a converted carport that is now used as a place to rest and rejuvenate in the outdoors. We can’t wait to welcome you into our home!

Stroll to the Swamp Rabbit Cafe & Trail

Renovated historic Mill House in a prime location! The McBeth House is a 5-minute walk to the Swamp Rabbit Cafe & Grocery with Swamp Rabbit Trail access. This 2 bedroom, one-bath home includes a king-sized bed & a twin-size trundle to comfortably sleep 4. Well-stocked with kitchen gadgets & amenities you may need. While you're here this is YOUR home! Whether it's relaxing on the porch, enjoying the downtown scene, or time spent in nature, here you're close to it all!

Greenville Modern Retreat - 8 minutes to Downtown

Decorated in a mid century modern theme, this home is perfect for couples and business travelers looking for a peaceful, modern aesthetic filled with natural light. This home is located in San Souci just 2.5 mi (8min drive) to downtown Greenville. It is also conveniently located 1/2 mi to the Swamp rabbit trail and the Swamp Rabbit Grocery. Please see “Where you’ll be” section for further description of location and the neighborhood. We're excited to have you join us!

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.