Guesthouse vacation rentals in Greenville County

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Popular amenities for Greenville County guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
Guesthouse in Travelers Rest
5 out of 5 average rating, 48 reviews

Travelers Rest Country Retreat Two miles to NGU

PeggyRating, 5 stars9 months ago
I can't say anything negative about Cliff and Mary's place. It is a gem. You watch horses graze on one side of the house and overlook a pond on the other side. Cliff and Mary are very responsive and go out of their way anticipating their guests needs, stocking the kitchen and fridge with snacks, coffee, cream, and other goodies. Any questions we had about the area were answered immediately. They are pleasant people that I would be glad to call new friends!
Top guest favorite
Guesthouse in Tryon
4.98 out of 5 average rating, 110 reviews

Historic Jockey Cottage, TIEC 20 mins, Tryon 5

CourtenayRating, 5 stars2 weeks ago
I’m selfishly not wanting to write this great review because I will be sad if the place is booked when I go back to Tryon! The place was perfect for my pup and I while showing at TIEC. The hosts are lovely, and the place stocked with a coffee bar and water, and the community itself is beautiful. Quiet, peaceful, yet super convenient for restaurants and shopping. I will be back! Also, apologies. I stole your box of tissue under the bathroom sink because my allergies were killing me at the horse show: I meant to replace it with one I night but I forgot this morning. I apologize again and thank you!
Guest favorite
Guesthouse in Pendleton
4.89 out of 5 average rating, 263 reviews

La Bella Farm

BryndenRating, 5 stars3 weeks ago
Had a lovely stay. Wonderful hosts, kept me informed and even answered all questions before they were asked. Was very peaceful, minimal noise day and night. A beautiful property and a very comfortable bnb. Would absolutely recommend staying here- especially for the price.
Top guest favorite
Guesthouse in Liberty
4.93 out of 5 average rating, 197 reviews

Holly Hideaway! 10 Highway miles to Clemson U!

RittaRating, 5 stars1 month ago
Jen’s Hideaway is the perfect private spot to come back to after visiting Central and Clemson. It is extremely clean and well appointed. The bed is very comfortable. Jen is a friendly host. She even baked us delicious blueberry muffins.
Guest favorite
Guesthouse in Simpsonville
4.94 out of 5 average rating, 244 reviews

Private Suite in Downtown Simpsonville

DarlaRating, 5 stars2 weeks ago
I had a great stay in Simpsonville, SC. Everyone was very helpful and polite. Thank you!
Guesthouse in Greenville
4.78 out of 5 average rating, 46 reviews

Quiet Guest Apartment in the Woods

JenniferRating, 5 stars32 months ago
Miranda's guest apartment was perfect for a long term stay. It was well equipped, neat, and ideally located with easy proximity to Paris Mountain State Park as well as downtown Greenville. Miranda was a wonderful host and prompt to respond the few times I needed something.
Guest favorite
Private room in Pelzer
4.98 out of 5 average rating, 128 reviews

South Oaks Guesthouse

JadaRating, 5 stars4 weeks ago
Diane was so helpful and patient with us. We were looking for a private spot for my husband’s son’s wedding and it was absolutely perfect. The tree line driveway is just breathtaking, we love the area so much we have been talking about going back out. When we walked in the room we noticed fresh flowers in the room and bathroom. We loved the little touches that Diane added, as well as the butterscotch coffee cake. It truly is 10/10 I’ve never had anything like it I almost ate it all in one sitting 🤭. We’re not much for sweets so that was very enjoyable. Very thoughtful add. We’re very picking with our bedding, bed, and oh my goodness it gave us the sleep we needed after a long flight. Not too soft or firm. We were very happy about that. We enjoyed our stay, and are so grateful for Diane she has been amazing and super quick with responding to us. Made it really easy for us to check out. I ended up making an error on my end as far as the booking and she did great with helping us.

Guest house rentals with a patio

Guest favorite
Guesthouse in Travelers Rest
4.83 out of 5 average rating, 6 reviews

Guest Cottage with Private Drive

AshleyRating, 5 stars3 weeks ago
I had a great stay! This place was quiet, clean, and the screened in porch with the TV was a great bonus!
Guest favorite
Guesthouse in Lyman
4.94 out of 5 average rating, 31 reviews

Budget Bliss: Cozy Elegance

Jonathan Rating, 5 stars3 weeks ago
Was very nice and cozy. the water pressure was perfect. host was super friendly and responded quicker than I expected. had great air conditioning so I never got hot. overall pleasent stay! the only downside I discovered was for some reason Domino's wouldn't deliver to that area, but that's Domino's fault, not the host. would definitely stay again!~
Guest favorite
Guesthouse in Greenville
4.9 out of 5 average rating, 69 reviews

Chic Studio with Private Deck

Pryncess AnjoleiqueRating, 5 stars3 weeks ago
It was a nice relaxing and peaceful. But I would like to worn all future guests not in a bad way or anything. But when you get there its on the right side not the left. Even if you get confused like I did you can ask Uyen and he'll help you out. I very likely will return for another stay.
Top guest favorite
Guesthouse in Pelzer
4.98 out of 5 average rating, 44 reviews

Serene country escape on 11 acres

JoshRating, 5 stars1 week ago
Amy thought of everything and more! Super responsive and provided a ton of information on the area. The space is extremely clean and roomy. Perfect spot to relax.
Top guest favorite
Guesthouse in Easley
5 out of 5 average rating, 49 reviews

Fun, cozy cottage for two w/games, deck in Easley

BaxterRating, 5 stars1 month ago
We enjoyed our stay on a trip to Clemson for a graduation. It was easy to find and so peaceful and quiet. Shannon and David have done a wonderful job of decorating and we enjoyed looking at everything. They pay attention to detail which makes for a pleasant stay. The kitchen had everything and the bathroom was clean and every need was provided for. We would definitely stay here again.
Top guest favorite
Guesthouse in Greer
4.96 out of 5 average rating, 49 reviews

Sugar Creek Retreat

WendellRating, 5 stars3 weeks ago
We really enjoyed our stay at Sugar Creek Retreat. The downstairs apartment is very clean and easy to access with its separate entrance. The kitchen was well appointed and allowed us to make a few meals - primarily breakfast - during our stay. The Sugar Creek neighborhood is very nice and quiet while being well located for quick access to both Greer and Greenville. Kristen shares in her listing that their family lives above so you will hear some foot traffic typically when their children are headed out or arriving home but it was not an issue during our stay. The queen bed is very good and on the firm side. Again, we really enjoyed our stay!!
Superhost
Guesthouse in Taylors
4.79 out of 5 average rating, 48 reviews

• Great Cottage near Downtown

SequoyaRating, 5 stars1 week ago
Mary was a lifesaver and hosted us short notice when we needed a place to stay last minute. The tiny cottage was clean and cozy. Mary was very friendly and welcoming. My son really enjoyed running and playing in the big backyard. We all enjoyed our stay and would stay again!
Top guest favorite
Guesthouse in Greenville
4.95 out of 5 average rating, 40 reviews

Tranquil 2BR Guest House on Pond by Furman

GinnyRating, 5 stars1 week ago
Our stay at Gabriella's was wonderful. It is close enough to major roads to get anywhere quickly yet in a quiet neighborhood and very private. The living room was comfortable, the kitchen was well equipped, the bedrooms were large and everything was beautifully decorated. With family new to the area, I've already asked to stay there again!

Guest house rentals with a washer and dryer

Superhost
Guesthouse in Travelers Rest
4.8 out of 5 average rating, 20 reviews

Quiet King Two Bedrm House

LESLIERating, 5 stars1 month ago
This was a quiet spot with friendly neighbors. Be careful if you walk to Travelers Rest as some dogs are off leash. One chased me onto a porch. This was a cross street to the rental location. The rest of the stay was nice and the hosts were very accommodating!
Guest favorite
Guesthouse in Taylors
4.96 out of 5 average rating, 72 reviews

The oaks cottage

EdnaRating, 5 stars3 weeks ago
Just amazing. Close to everything. It was perfect.
Guest favorite
Guesthouse in Taylors
4.97 out of 5 average rating, 139 reviews

Just off Main near Taylors Mill - Clean & Comfy

CathyRating, 5 stars1 month ago
We were in town for family events. Natalie’s place was exactly as described, clean and spacious for my Mom, husband and I. Fully equipped kitchen , comfy living area and plenty of linens. Check in instructions were clear and Natalie was easy to communicate with. Would stay again if the opportunity arises.
Guest favorite
Guesthouse in Duncan
4.98 out of 5 average rating, 63 reviews

Adorable renovated private house w/ parking.

LisaRating, 5 stars2 months ago
Great place to stay!
Top guest favorite
Guesthouse in Mauldin
5 out of 5 average rating, 8 reviews

Beautiful guest house

PeggyRating, 5 stars1 month ago
Peaceful place to stay in a quiet neighborhood. Convenient to interstate and everything we needed. James was proactive in communicating and clear in his instructions. Would stay again! Two thumbs up 👍🏼
Guest favorite
Guesthouse in Greenville
4.96 out of 5 average rating, 93 reviews

Nishleigh's Nook - West End Downtown Greenville

MicahRating, 5 stars2 days ago
Beautiful apartment & SO clean. We had a wonderful, short stay! Nicholas was very proactive when there was a chance of service outages due to storms & it was very appreciated. Would definitely recommend & stay again ourselves!
Top guest favorite
Guesthouse in Greenville
5 out of 5 average rating, 10 reviews

800 Sq Ft close to downtown

CaraRating, 5 stars2 days ago
Great location for us as we wanted to be close to the downtown area but not in it. Neighborhood was quiet & parking was easy.
Top guest favorite
Guesthouse in Greenville
4.99 out of 5 average rating, 298 reviews

Prime Downtown Home—Walk to Main St, Trails&Dining

ArleneRating, 5 stars18 months ago
The loveliest space imaginable. It is so well built, a custom home, the floors, the cabinets, the tile, everything was so classic and comfortable and well appointed. Walked to and from the Peace Center for a show and walked all over town, very safe, very clean neighborhood. Fabulous stay! Ready to plan the next trip back.

Destinations to explore