Family-friendly vacation rentals in Florence

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Florence

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite

The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.

Cabin in Rowesville

4.95 out of 5 average rating, 168 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Guest favorite

A charming country estate is highlighted with a wrap-around porch surrounded by lush greenery. The architectural details feature brick and wood elements, with a tall chimney visible. Sunlight gently illuminates the exterior, showcasing the inviting atmosphere of the property.

Home in Kingstree

4.95 out of 5 average rating, 112 reviews

magical 1840s farm house getaway

Centuries old country estate with magical ambiance, art and antiques, beautiful views and wrap around porches. Relax in the hot tub in your own private oasis or gather with friends and family around the fire pit. Multiple bird feeders and grand live oaks, magnolias, fruit trees and a kitchen garden. Chefs kitchen will be stocked with fresh eggs, herbs and seasonal veggies. Sit and sip on the porch while enjoying the views of farmer's field and listing to the moos of the cows. Groups welcome!

Top guest favorite

A tiny home is presented with a covered front porch featuring wooden railings and a set of steps leading to the entrance. The exterior showcases a combination of light and dark siding, along with a window air conditioning unit. Lush grass surrounds the home.

Tiny home in Wade

4.95 out of 5 average rating, 266 reviews

Tiny Home Farm, just off I-95, 10 min Fayetteville

Located 1 min off I-95 & 10 min from Fayetteville on the McDaniel Pine Farm, quietly nestled down a beautiful rock path you’ll feel right at home immediately. Tiny home with 1 bathroom, small kitchen & living area couch converts into a full bed. You’ll enjoy a beautiful outside living area complete with fire pit, sitting area and front porch chairs to sip your coffee overlooking the farm. Plenty of grass & open area for your pet, small kids or just to take an evening stroll around the farm.

Top guest favorite

A single-story home is shown with a welcoming front porch and bright red door. The exterior is accented by black shutters and a white facade, surrounded by a grassy lawn with small trees. A clear blue sky with soft clouds is visible in the background.

Home in Hartsville

5 out of 5 average rating, 128 reviews

Manchester Place

Hartsville is a Charming Town with plenty of family activities, shops, and dining. Home is located in the quiet Fox Hollow subdivision which is just outside the city limits but still close to downtown. Robinson Nuclear Plant 10 min. Sonoco 7 min. Coker University 7 min. Downtown Hartsville 7 min. Carolina Pines Hospital 9 min. McLeod Hospital Florence 42 min. Byerly Park 9 min. Hartsville Center Theater 6 min. Governor's School for Science and Mathematics 9 min. Darlington Raceway 22 min.

Top guest favorite

The exterior of a quaint cottage features white siding, green shutters, and a covered porch. An American flag is displayed, and two chairs sit on the porch. A gravel driveway leads to the home, surrounded by shade trees in a peaceful setting.

Cottage in Timmonsville

4.97 out of 5 average rating, 974 reviews

*Cottage Near Florence and I-95* 3 Bedrooms

Located just 5 mins from I-95 and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, pls) but are not allowed on our beds. 🧺. King bed in master, 3 TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. Absolutely no smoking ON OUR PROPERTY ($200 extra fee). Come stay with us!! 😊

Top guest favorite

The exterior of the hermitage is seen at dusk, highlighted by a warm glow from outdoor lights. The rich orange facade contrasts with the pink and purple hues of the sunset sky. Nearby trees frame the scene, and a landscaped area features decorative plants.

Place to stay in Effingham

4.97 out of 5 average rating, 142 reviews

Gated and Private Catholic Hermitage house

Saint Michael Hermitage and retreat is a serene, gated, private home that is for 1-3 guests looking for a quiet stay while traveling or as a retreat destination. You will self check into your Hermitage after you obtain a gate code. There is a prayer chapel close by on the property. It is pet friendly for a well trained pet. There is Catholic iconography throughout the home. It is warm and inviting. There is a full kitchen, washer/dryer for your convenience and complementary coffee/tea.

Guest favorite

A well-appointed sleeping area contains two beds, each dressed in light-colored bedding with decorative throws. A bedside lamp is positioned between the beds on a dark nightstand. Natural light enters through partially covered windows, highlighting the room's neutral tones and horse-themed wall art.

Barn in Society Hill

4.95 out of 5 average rating, 353 reviews

Burchs Carriage House

Private carriage house sitting adjacent to the most historic estate home in the lovely town of Society Hill. Separate entrance for guests which accommodates large horse trailers. Property caters to all animals! Kitchenette (microwave, toaster oven and hot plate), washer/dryer, Apple TV and wifi. Continental breakfast, wine/snacks provided. BBQ grill also. 2 stalls with paddocks. 12 x 12 and 10 x 12. Rooms are as they would be at your own home, separate from each other. See photo 13.

Top guest favorite

A stand-alone apartment building is shown, featuring a low brick exterior and a gabled roof. There are several windows framed with white shutters, allowing natural light to enter. The well-maintained lawn is bordered by neatly trimmed bushes, complementing the overall tidy appearance.

Home in Lake City

4.93 out of 5 average rating, 254 reviews

Home Away From Home Apt 3 - A Hidden Gem

Stand Alone (not a part of the main house) 1 Bed-Room Apt. with Full furnished Kitchen, Full Bath, Private Entrance, private bedroom with door, Private Parking. Living Room- Dining Combo. Fully Furnished. High-Speed WI-Fi, 2 ROKU TVs, 1 in BR & 1 in LR, 1/2 way from New York to Miami, Hablamos Espanol, Fresh Brewed In-Room Coffee. Easy 1-mile walk on Main St. to uptown. 23 miles from I-95, 60 miles to Myrtle Beach, 23 miles to Florence, 1&1/2 hours to Charleston and Columbia.

Top guest favorite

The cozy interior features rustic wooden beams and a blend of warm tones. A spacious bed is positioned against a wall with a peacock artwork. A kitchenette area is visible, alongside a small dining table and a television, providing a comfortable, multifunctional living space.

Farm stay in Timmonsville

4.95 out of 5 average rating, 659 reviews

The Cottage at Dream Acres & Petting Zoo I-95/I-20

The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!

Guest favorite

The kitchen features modern appliances, including a stainless steel refrigerator and an electric stove. Natural light fills the space through multiple windows. A wooden dining table is visible, accompanied by a set of chairs. A doorway leads to the outside.

Home in Hartsville

4.84 out of 5 average rating, 131 reviews

Quaint 2BR home w access to Black Creek & downtown

Our freshly renovated home sits in a family-oriented neighborhood only a mile from downtown Hartsville and Kalmia Gardens and includes access to Black Creek. This 600 sf home features 2 bedrooms, 1 bath, a full kitchen, washer and dryer and an open living area. Digital antenna reception for smart-tv and high speed wi-fi internet. Small dogs will be considered for stays on a case-by-case basis. Pet stays require prior approval from the hosts and will involve additional fees.

Guest favorite

A charming poolside cottage is surrounded by lush palm trees and vibrant plants. The outdoor space features a dining set on a paved patio, providing a tranquil area for relaxation. The entrance to the cottage is easily accessible, enhancing the inviting ambiance.

Guesthouse in Florence

4.93 out of 5 average rating, 863 reviews

The Cottage by the Pool: Close to Interstates

New floors and paint in January of 2023. Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

Top guest favorite

A living room area features a red couch and a beige sofa, arranged near a wooden table on a patterned rug. A brick fireplace is flanked by a standing lamp. A television is mounted on the wall, and a set of French doors provides access to another room.

Home in Hartsville

4.97 out of 5 average rating, 126 reviews

Cozy little home away from home

This little gem is sure to make you feel at home! Our Barefoot Bungalow sits on a quiet residential street just 3 minutes from downtown Hartsville. The beds are comfortable, the couch is just waiting for you to settle in, and the kitchen was set up by two people who LOVE to cook. There's even an outdoor space to have a quick meal or enjoy the cool of the evening. This is my little dream cottage and I am so happy to be able to share it with you!