
House vacation rentals in Florence
Find and book unique houses on Airbnb
Top-rated house rentals in Florence
Guests agree: these houses are highly rated for location, cleanliness, and more.

Kuker Cottage Downtown Florence-Near I95 & I20
Kuker Cottage is a beautifully restored Florence home in the heart of downtown. Perfectly situated halfway between New York and Florida, it is an ideal overnight stopping point. Plenty of space to spread out, offering families room to unwind after a long day of traveling. This home has been beautifully updated and is ready to host you, whether for a short or an extended stay. 2 queen beds, one twin bed, full bath, kitchen, wifi and TV. Walkable to parks and restaurants. 4 miles from I95 and I20

Renovated 2 BR/2 B Townhouse Cozy & Clean
Keep it simple at this peaceful, centrally-located, and renovated townhouse close by I-95 and I-20 and within 15 mins. to the Florence Center, downtown Florence, many restaurants, and McLeod and MUSC Florence. House is located in a safe neighborhood with 2 queen beds and 1 sofa bed in the living room. Enjoy being outdoors? Relax outdoors on your own private patio, go on a walk around the neighborhood, or go on an adventure. The Rail Trail & Ebenezer Park are minutes away. Utilities included.

magical 1840s farm house getaway
Centuries old country estate with magical ambiance, art and antiques, beautiful views and wrap around porches. Relax in the hot tub in your own private oasis or gather with friends and family around the fire pit. Multiple bird feeders and grand live oaks, magnolias, fruit trees and a kitchen garden. Chefs kitchen will be stocked with fresh eggs, herbs and seasonal veggies. Sit and sip on the porch while enjoying the views of farmer's field and listing to the moos of the cows. Groups welcome!

Wateree Sunsets, dock, family fun, w/ king bed!
Welcome to On The Rocks @ Lake Wateree, SC. Come and enjoy the best that South Carolina has to offer right here at the lake. This home is set out on its own peninsula with two coves. Perfect for boating, fishing, kayaking, and relaxing while watching the best sunsets by the fire pit. We offer so much with your stay, you will not want to leave. This is the perfect get away from the hustle and bustle of that nine to five life. We are minutes away from boat ramps, restaurants, and grocery stores.

Manchester Place
Hartsville is a Charming Town with plenty of family activities, shops, and dining. Home is located in the quiet Fox Hollow subdivision which is just outside the city limits but still close to downtown. Robinson Nuclear Plant 10 min. Sonoco 7 min. Coker University 7 min. Downtown Hartsville 7 min. Carolina Pines Hospital 9 min. McLeod Hospital Florence 42 min. Byerly Park 9 min. Hartsville Center Theater 6 min. Governor's School for Science and Mathematics 9 min. Darlington Raceway 22 min.

Charming 3 bedroom bungalow
You’ll be close to everything when you stay at this centrally-located bungalow. You’re a 1 minute walk from beautiful Swan Lake Iris Gardens. Drive to downtown Sumter in 4 mins & Shaw AFB in 15 mins. Enjoy the cozy porch or outdoor fire pit with seating & basketball goal. There's a fenced yard for kids/pets. 3 bedrooms/1 bath; extra room with loveseat, TV, games/books/toys. Spacious kitchen & laundry room for your convenience. Enjoy free Wifi & Smart TVs. I am a licensed real estate agent.

New Home! Only 15 min to Shaw/Sumter. Dog friendly
Built in March 2022 single story home is full of amenities. High speed internet Upgraded cable 15 min to Shaw AFB Conveniently located between Sumter & Camden Premium mattresses Hotel like stay Backyard w/deck Iron/ironing board Vanity table 55 and 65 inch tv's Home office bedroom combo/printer, desk/ monitor and futon (can sleep 2 kids or 1 adult). Laundry room New appliances Kitchen is full of amenities Outdoor lighting Pet friendly! Dog toys, treats, indoor kennel Fenced in dog run

Charming Home in Florence, SC
Welcome to Florence, South Carolina! This inviting 3-bedroom, 2-bathroom home is a haven of comfort and convenience. With four queen beds, it comfortably accommodates a group of friends or family. Step into the fully stocked kitchen, relax in the cozy living space, equipped with smart TVs for entertainment. The fenced backyard offers both privacy and a secure play area for your furry friends. Enjoy outdoor gatherings at the picnic table. Convenient amenities include a washer and dryer.

The Parkside Retreat
Welcome to our beautiful Airbnb! Located next to a serene and picturesque park, our home is perfect for families or groups looking for a comfortable stay. With two king master suites and a cozy kids room, we can accommodate up to 6 guests, making it an ideal choice for a family or a group getaway. Each master suite features a comfortable king-sized bed, plush linens, and ample storage space providing a tranquil retreat after a day of exploring the local attractions. Book your stay today!

Home Away From Home Apt 3 - A Hidden Gem
Stand Alone (not a part of the main house) 1 Bed-Room Apt. with Full furnished Kitchen, Full Bath, Private Entrance, private bedroom with door, Private Parking. Living Room- Dining Combo. Fully Furnished. High-Speed WI-Fi, 2 ROKU TVs, 1 in BR & 1 in LR, 1/2 way from New York to Miami, Hablamos Espanol, Fresh Brewed In-Room Coffee. Easy 1-mile walk on Main St. to uptown. 23 miles from I-95, 60 miles to Myrtle Beach, 23 miles to Florence, 1&1/2 hours to Charleston and Columbia.

Quaint 2BR home w access to Black Creek & downtown
Our freshly renovated home sits in a family-oriented neighborhood only a mile from downtown Hartsville and Kalmia Gardens and includes access to Black Creek. This 600 sf home features 2 bedrooms, 1 bath, a full kitchen, washer and dryer and an open living area. Digital antenna reception for smart-tv and high speed wi-fi internet. Small dogs will be considered for stays on a case-by-case basis. Pet stays require prior approval from the hosts and will involve additional fees.

Located 100 feet from The Darlington Raceway!
This cute little bungalow is located across the street from The Darlington Raceway. Just a few steps puts you at the door of the famous Joe Weatherly Stock Car Museum. We are also within walking distance to Manheim Auto Auction. The Raceway Grill, a favorite of Dale Earnhardt, is located across the street ! If you are here during the week, South of Pearl, Darlington's finest eating establishment, is located in uptown Darlington. WE DO NOT HAVE A STOVE OR WASHER/DRYER
Popular amenities for Florence house rentals
House rentals with a pool

Beach House with indoor pool!

Surfside Beach Home with Golf Carts (183 GB)

Mermaid Cove 4BR 3.5 Bath, 2 bks away frm beach

Luxury Lakefront Chalet W/Pool, Hot Tub & Beach

Luxury Villa in Caribbean-Style Beach Resort

Berkeley - Near Brookgreen, Beach Pass Incl

Quick Walk to Beach, Private Pool, Fast Wifi!

Ultimate Lake Marion Dream Home W/Pool & Swim Spa
Weekly house rentals

Spacious 3 bd Home with Office, GameRoom & Balcony

Crystal Place Near MUSC and Mcleod Hospital

Charming and spacious 4-bd 2 full ba WiFi, AC

Peaceful Country Getaway

Peaceful Pine Stays/ 5 min. from Mcleod hospital

The Happy Sac

Home on Broad

Newly Remodeled 2 bed house
Private house rentals

Gorgeous Southern Home in Cheraw

Quiet country stay; close to I95

Twin Cedars - less than a mile to Broomsedge Golf!

Spacious, Historic Home for 12 - Near Myrtle Beach

Camden Tea-Garden Blue wing

WOW! The Purple Heart Cottage Whole House, Main St

* NEW * Cozy and Clean 3B/2Bath

Home Sweet Home
When is the best time to visit Florence?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$25,098 GYD | G$24,889 GYD | G$24,262 GYD | G$24,053 GYD | G$25,726 GYD | G$24,053 GYD | G$24,053 GYD | G$23,007 GYD | G$24,053 GYD | G$20,915 GYD | G$23,634 GYD | G$23,216 GYD |
| Avg. temp | 9°C | 11°C | 14°C | 18°C | 22°C | 25°C | 27°C | 26°C | 24°C | 19°C | 14°C | 11°C |
Quick stats about house rentals in Florence

Total vacation rentals
Explore 80 vacation rentals in Florence

Nightly prices starting at
Florence vacation rentals start at G$8,366 GYD per night before taxes and fees

Verified guest reviews
Over 2,080 verified reviews to help you choose

Family-friendly vacation rentals
60 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Rentals with dedicated workspaces
50 properties have a dedicated workspace

Wi-Fi availability
70 of Florence vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Florence rentals

4.9 Average rating
Florence stays are highly rated by guests—averaging 4.9 out of 5!
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