
Vacation rentals in Florence
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Florence
Guests agree: these stays are highly rated for location, cleanliness, and more.

Kuker Cottage Downtown Florence-Near I95 & I20
Kuker Cottage is a beautifully restored Florence home in the heart of downtown. Perfectly situated halfway between New York and Florida, it is an ideal overnight stopping point. Plenty of space to spread out, offering families room to unwind after a long day of traveling. This home has been beautifully updated and is ready to host you, whether for a short or an extended stay. 2 queen beds, one twin bed, full bath, kitchen, wifi and TV. Walkable to parks and restaurants. 4 miles from I95 and I20

Renovated 2 BR/2 B Townhouse Cozy & Clean
Keep it simple at this peaceful, centrally-located, and renovated townhouse close by I-95 and I-20 and within 15 mins. to the Florence Center, downtown Florence, many restaurants, and McLeod and MUSC Florence. House is located in a safe neighborhood with 2 queen beds and 1 sofa bed in the living room. Enjoy being outdoors? Relax outdoors on your own private patio, go on a walk around the neighborhood, or go on an adventure. The Rail Trail & Ebenezer Park are minutes away. Utilities included.

Blu Grace Farm Apartment
Our barndo is located on our quaint 10 acre farm. The barn sits in the center of two pastures overseeing highland cows, horses, alpaca, donkeys, sheep and ducks. A cup of coffee, the sound of the rooster crowing while rocking under the awning is an experience in itself. Pet and feed the livestock during your visit. We are conveniently located near several wedding venues in historic Marion county and just an hour from Myrtle Beach. This is a rustic and peaceful farm experience you won’t forget.

Manchester Place
Hartsville is a Charming Town with plenty of family activities, shops, and dining. Home is located in the quiet Fox Hollow subdivision which is just outside the city limits but still close to downtown. Robinson Nuclear Plant 10 min. Sonoco 7 min. Coker University 7 min. Downtown Hartsville 7 min. Carolina Pines Hospital 9 min. McLeod Hospital Florence 42 min. Byerly Park 9 min. Hartsville Center Theater 6 min. Governor's School for Science and Mathematics 9 min. Darlington Raceway 22 min.

*Cottage Near Florence and I-95* 3 Bedrooms
Located just 5 mins from I-95 and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, pls) but are not allowed on our beds. 🧺. King bed in master, 3 TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. Absolutely no smoking ON OUR PROPERTY ($200 extra fee). Come stay with us!! 😊

The Little Cottage, Stateburg
Take it easy at this unique and tranquil getaway. The Little Red Cottage features a small bedroom with a double size bed and a closet, a spacious living room with sofa/roku TV and computer desk, and a bathroom with shower. It is nestled on 6 serene acres, among massive windswept Live Oaks dripping with Spanish moss, Palmettos, azaleas, camellia, magnolias and creape myrtle, yet so conveniently close to Shaw Air Force base, 30 mins to Columbia and Camden, close to all Sumter's attractions.

Gated and Private Catholic Hermitage house
Saint Michael Hermitage and retreat is a serene, gated, private home that is for 1-3 guests looking for a quiet stay while traveling or as a retreat destination. You will self check into your Hermitage after you obtain a gate code. There is a prayer chapel close by on the property. It is pet friendly for a well trained pet. There is Catholic iconography throughout the home. It is warm and inviting. There is a full kitchen, washer/dryer for your convenience and complementary coffee/tea.

Chauffeur’s Apartment on Historic Property
Enjoy the former chauffeur's quarters located on the grounds of our National Register of Historic Places property with access to the tranquil gardens of the Manor House. The kitchen is complete and the comfortable full-sized bed should provide a good night's rest. Downtown activities are within easy walking distance. There are multiple seating areas to enjoy the extensive gardens on the one acre grounds that are shared with the main property. We cannot host guests under the age of 16.

The Cottage at Dream Acres & Petting Zoo I-95/I-20
The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!

Boho Private Downtown Stay Near I-95 & Hospital
Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including covered parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!

#4 Away from Home, Upgrade the Space, Not the Rate
Located on Main Street in a family home that has been updated to be like brand new. Apartment 4 has one bedroom with door, a private entrance, bath and dressing area, micro-kitchen, living & dining combination. Amenities include SPECTRUM & ROKU TV, in B.R. and L.R., wifi, front door parking, in room fresh brewed coffee (Cafe Valet) and Wind River Salon Products. Downtown Lake City is an easy one mile walk along Main Street. 1/2 way from New York to Miami. Hablamos Espanol.

Cottage by the Pool: Close to Interstates
Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.
Popular amenities for Florence vacation rentals
Other great vacation rentals in Florence

Mulberry Cabin, a rustic tiny house cabin

Peaceful Country Getaway

Cozy Florence Retreat Near Civic Center & I-95

Woodland Country Camper Near Florence & I-95

The Farmhouse @ Goat Daddy's

Completely remodeled 3 bedroom upgraded home

Governor's Square at Coventry @ I-20/I-95

Private Cottage, Guesthouse, Queen Bed & Kitchen
When is the best time to visit Florence?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$21,732 GYD | G$22,359 GYD | G$22,359 GYD | G$21,732 GYD | G$23,403 GYD | G$21,941 GYD | G$21,941 GYD | G$22,359 GYD | G$21,314 GYD | G$19,851 GYD | G$20,269 GYD | G$20,896 GYD |
| Avg. temp | 9°C | 11°C | 14°C | 18°C | 22°C | 25°C | 27°C | 26°C | 24°C | 19°C | 14°C | 11°C |
Frequently Asked Questions
Are there hotel rentals with a dedicated workspace in Florence?
Yes! Work meets play with ease at over 10 hotel rentals in Florence featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there family-friendly house rentals in Florence?
Florence has more than 60 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do hotel rentals in Florence have wifi?
Absolutely! We offer over 10 hotel rentals with wifi in Florence. Enjoy a tailored experience with all the comforts you desire.
How much does it cost to stay in hotel rentals in Florence?
Experience the best of Florence with our hotel rentals, starting at about $60 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Are there Florence hotel rentals on Airbnb with pools?
Yes! Dive into the perfect getaway at one of over 10 hotel rentals with pools in Florence, available on Airbnb. Make a splash and soak up the sun in style!
Are there pet-friendly house rentals in Florence?
Four-legged friends are welcome in Florence. Choose from more than 30 house rentals for guests traveling with pets.
Do house rentals in Florence have self check-in?
Absolutely! We offer over 10 house rentals with self check-in in Florence. Enjoy a tailored experience with all the comforts you desire.
What are the most popular amenities for House Rentals in Florence?
Enhance your stay in our House Rentals with the most popular amenities: over 70 homes with wifi, over 10 homes with self check-in, and more. Indulge in the ultimate retreat, tailored to your preferences.
Quick stats about vacation rentals in Florence

Total vacation rentals
Explore 160 vacation rentals in Florence

Nightly prices starting at
Florence vacation rentals start at G$8,358 GYD per night before taxes and fees

Verified guest reviews
Over 6,920 verified reviews to help you choose

Family-friendly vacation rentals
80 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 70 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
100 properties have a dedicated workspace

Wi-Fi availability
150 of Florence vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Florence rentals

4.8 Average rating
Florence stays are highly rated by guests—averaging 4.8 out of 5!
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