Family-friendly vacation rentals in Depew

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Depew

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Superhost
The exterior of a single-story home is displayed, featuring a well-maintained lawn with vibrant green grass. A wooden deck is positioned at the entrance, providing a welcoming access point. Trees and a clear blue sky add a natural backdrop to the property.
Home in Orchard Park
4.94 out of 5 average rating, 103 reviews

Cozy Stay at Home in Orchard Park

Game Day Getaway in Orchard Park Welcome to your perfect retreat in Orchard Park, NY! This newly renovated home is just 5 minutes from Highmark Stadium, ideal for Bills fans. Located on a quiet street, it’s also 5 minutes from the charming Village of Orchard Park and 10 minutes from downtown Buffalo. Enjoy a fully equipped modern kitchen, cozy bedrooms, and a spacious deck for relaxing. Whether for game day, exploring, or a peaceful escape, this home has everything you need for a memorable stay.

Superhost
A cozy sleeping area features a spacious bed with a light-colored coverlet. Decorative pillows are arranged at the head of the bed, complemented by bedside tables and lamps. Natural light filters through sheer white curtains, enhancing the calming ambiance of the room.
Guesthouse in Cheektowaga
4.79 out of 5 average rating, 234 reviews

Warm & Cozy private Guesthouse/ Entire place.

Hi there! This is Aklima and Farhad, and we’re thrilled to have you stay at our guest house. It’s connected to our house, but both have their own private entrances. Just a friendly reminder, you might spot our kids playing in the backyard, so please be mindful of that. We love living here and meeting new people, which is why we started Airbnb. We’re committed to providing the best hospitality at an affordable price. This place is surrounded by nature and in a peaceful area! Enjoy your stay!

Top guest favorite
A decorative deer head sculpture with antlers and glasses is positioned atop a stack of books. The books include titles by Garth Stein, Lauren K. Denton, and Ta-Nehisi Coates. Natural light filters through the window shades, illuminating the cozy living room setting.
Apartment in Williamsville
5 out of 5 average rating, 101 reviews

Sunny & Spacious 1st Floor Walk to Dining & Shops

Beautiful Village first floor apartment Circa 1910, lovingly restored with modern amenities. 2 queen bedrooms, 1 full bath. Sun filled living room featuring original leaded glass windows & large designated work space. Spacious dining room & farmhouse kitchen. Walk to local restaurants, shops, parks & festivals (1/2 mi to heart of village). Peaceful storybook setting. Close to Glenn Falls, Island Park, UB, City of Buf, Airport, Niagara Falls, Bills Stadium, Albright Knox Art Gallery GO BILLS🎉

Top guest favorite
A game room features a pool table in the foreground, surrounded by several high-backed chairs and small tables. A wall-mounted television and artworks are visible in the background, with mirror accents enhancing the bright, spacious environment.
Home in Williamsville
4.98 out of 5 average rating, 120 reviews

Option B | GameRoom, Location, Patio, Pet-Friendly

Follow us at @ondemandbungalows for more photos! Bring the whole family to this recently updated, traveler-inspired, comfy and spacious home in the heart of Village of Williamsville, NY. This 2-story, 2,500 square foot unique home is loaded with charm. With a game room, quaint patio, 2 living rooms, and 7 beds & 3.5 bathrooms, this home is perfect for families and large groups. Enjoy the peace and quite of suburbia just steps away from the shopping, nightlife and entertainment of Main Street.

Top guest favorite
A welcoming living area features a comfortable sectional sofa and a gray armchair. A coffee table sits on a patterned area rug, while soft light is provided by table lamps. The room is brightened by natural light from the windows and is designed for relaxation.
Home in Orchard Park
4.98 out of 5 average rating, 195 reviews

Cottage at Orchard Park Village

Cozy cottage nestled in the heart of the Village of Orchard Park, NY. Home has been renovated top to bottom but maintains it's original charm! Located in a very safe neighborhood on a quiet street. Walking distance to Village amenities (restaurants/bars/coffee shops) and minutes from Highmark Stadium (home of the Bills)! 15 minutes to downtown Buffalo, 20 minutes to Buffalo Niagara International Airport, and 40 minutes to Niagara Falls. **10% DISCOUNT FOR VETERANS AND ACTIVE DUTY WITH ID**

Guest favorite
A vibrant planter filled with pink flowers hangs next to a spacious heated pool. Lush greenery surrounds the pool area, complementing the calm blue water. A patio area with a rustic chair is visible, inviting relaxation by the poolside.
Home in Alden
4.91 out of 5 average rating, 120 reviews

Carols Giant Heated Pool Buffalo, NY

Do you enjoy luxury? You and your family have our entire home to enjoy sleeps 5 Features : piano, fireplace, fenced in pool :vaulted gazebo Our home includes 3 bedrooms (queen beds) , 2 baths, master suite has bath Deep soaker tub & shower, washer/dryer a beautiful gazebo at the poolside , charcoal grill available, inground private heated pool. pool open may 28 2024 Our home is short drive to falls approx 40 mins Uber to Buffalo Niagara airport in 18 m Darien Lake (15 min

Top guest favorite
A single-story bungalow is showcased with a well-maintained lawn. The brick exterior is complemented by large windows that allow natural light. Neatly trimmed bushes and shrubs frame the entrance, while a pathway leads to the front door. A lamp post stands to the right, adding subtle illumination.
Home in Cheektowaga
4.94 out of 5 average rating, 105 reviews

Bungalow near BuffaloNiagara International Airport

Relax and unwind at this peaceful bungalow in suburban Buffalo. Comfortable 3-bedroom house located 2 miles from airport, 13.4 miles from Bills Stadium, 24 miles from Niagara Falls and only 15-minute drive from downtown Buffalo, NY. Two of the bedrooms are equipped with a queen-sized bed and the 3rd bedroom has a full sized bed. With plenty of storage space in the dressers and closets. Full kitchen/dining area. Laundry is available on site with a washer and dryer located in the basement.

Guest favorite
A living area features a wall-mounted television above a rustic wooden table. A small ladder shelf stands to the left, adorned with decorative items. The kitchen area is visible in the background, showcasing wooden cabinets and coffee-making equipment.
Apartment in Depew
4.8 out of 5 average rating, 428 reviews

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Top guest favorite
The exterior of the timber-frame home is shown, featuring large two-story windows and wood accents. A covered veranda extends from the structure, offering seating. Surrounding greenery and manicured grass enhance the natural setting, inviting a peaceful retreat in the countryside.
Home in East Aurora
4.97 out of 5 average rating, 129 reviews

Timber-frame home on 12 wooded acres

Featured in Buffalo Spree and Artvoice, this timber-frame home features stunning hickory and black walnut interiors illuminated by two-story windows that face the morning sun. Radiant floor heating and earthen-plaster climate design. Wake up in queen and king beds, lounge under covered verandas, and shop right next door at Thorpe’s organic farm store. • 7 minutes from the Village of East Aurora • 24 minutes from Bills stadium • 1 hour from Niagara Falls

Top guest favorite
A spacious balcony extends from the second floor, featuring two outdoor chairs and a small table. The view showcases a lush green lawn leading to the lake, framed by residential houses and trees under a clear blue sky.
Cottage in Fort Erie
4.96 out of 5 average rating, 152 reviews

Steps to the Beach + Lakeviews + HotTub + Elevator

Unwind at this The Red Lakehouse just steps from the beach, featuring a private hot tub, fire pit, and covered balcony with Lake Erie views. Perfect for families, groups, and getaways, this professionally designed home offers 3 bedrooms with private ensuites for ultimate comfort and privacy. Minutes to Niagara Falls, Crystal Beach, and the USA border — yet tucked in a quiet, relaxing neighbourhood. A spotless, thoughtfully curated stay.

Top guest favorite
The studio features an open layout with a cozy seating area including a gray sofa and matching chairs. A dining table accommodates four, and a spacious bed is present in the corner. Natural light filters through the window treatments, highlighting the neutral color scheme.
Guest suite in Lancaster
4.91 out of 5 average rating, 199 reviews

Work or Play this is your Home Away!

Newly remodeled private studio with private entrance. Lots of parking space. 700sq ft.of living space for you to enjoy! Private balcony overlooking stunning backyard views with a pond. Only 13 min away from Buffalo airport! Shopping centers within a mile. Downtown Buffalo- 20 min. drive Flix Movie Theater- 2 min. drive New Era field- 20 min. drive Niagara Falls- 40min. drive Galleria Mall- 12 min. drive

Top guest favorite
A charming exterior view showcases a white picket fence surrounding a well-kept yard. A lush green lawn is framed by flower beds, and a gazebo is visible in the background, complemented by mature trees providing shade.
Apartment in Williamsville
4.95 out of 5 average rating, 166 reviews

Cozy Williamsville apartment at Madison Place

Cozy 1 bedroom 2nd floor apartment Eat in kitchen with countertop height seating 2 Queen size beds (bed & fold out couch) Brand new built in dishwasher & microwave oven All cookware, silverware & kitchen appliances Fully furnished with all linens, towels and starter supply of soaps, shampoos. Ample closet space and storage Whole house water filter Laundry located in basement Off street parking for 2 cars

Popular amenities for Depew family-friendly rentals

  1. Airbnb
  2. United States
  3. New York
  4. Erie County
  5. Depew
  6. Family-friendly rentals