
Apartment vacation rentals in Depew
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Top-rated apartment rentals in Depew
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The Restful Nest ~ come and stay in rest and quiet
Restful comfort awaits you on a quiet street in quaint Akron Village! Off street parking for two cars. King & queen beds, hypoallergenic bedding, on point décor, Smart TV's, WIFI, separate office, fully outfitted kitchen, outdoor grill/table. 5 min to Sterling, Timberlodge & Akron Acres wedding venues, 10 min to I-90, central to Buffalo Airport, downtown Buffalo, Niagara Falls, Letchworth, Six Flags Darien, skiing, golf! Shops, bike path & Akron Falls Park are within walking! SEE MY GUIDEBOOK!

The 2D Spot!
Buffalo's 1st official 2D Airbnb; all hand painted by local Artists. With ideal proximity to DT Buffalo, Elmwood Village & Allentown, you'll find yourself at the heart of the city's culture. Also just a 25 minute drive to the iconic Niagara Falls. Whether you're a first time visitor to Buffalo or a local seeking a unique escape, The2DSpot invites you to step inside the pages of a comic book. Immerse yourself in a world of imagination & book your stay today! Experience Buffalo like never before.

Charming Neighborhood Retreat
This suite is the entire second floor of our home. Three bedrooms, one has an adjoining door to a larger room, box car style. Private, full bath plus 1/2 bath, kitchenette - microwave, small refrigerator. Main entrance is shared with owners (classical musicians) who live downstairs. Within walking distance: restaurants, bakeries, and 10 minutes from UB campuses and airport. Quiet neighborhood, sorry no parties. We do charge $10 per additional person so we can keep our cleaning fees lower!

Cute&cozy Hamburg NY bungalow - 1 BR/1 bath
Very cute, bungalow, 1 BR, 1 Bath, living room, & kitchen. Newly redone with all new furniture & updated décor. BR has a Queen memory foam mattress. LR sofa is a memory foam sleeper. Small fully functional kitchenette. Private patio, perfect for enjoying your coffee ; the park-like backyard neighbors on the golf course of a beautiful country club , allowing for a quiet ,serene and private atmosphere . Netflix, etc w/ an Amazon Fire Stick. No broadcast or cable tv,Parking for one car only

Close to Niagara Falls and Airport, Mall nearby
Niagara Falls is only 30minutes away.Very nice neighborhood.4minutes from Galleria Mall. Plus many more stores nearby.Many places to eat and have some drinks! Sleeps-5 we have a clean pack and play for your little one. Has own keypad entrance. Couch in living room , roll away bed. One bedroom has a queen bed and tv.The 2nd bedroom has a twin bed and offers tv and a workspace. Very clean! Kid friendly and pet friendly.Pets can do their business out front. There are dogs that use the back yard.

Meticulous Main St. Ranch 2 Bd Lux Apt. Rear Unit
This well-appointed, recently renovated, 1200 sq. ft. ranch duplex apt. is located on Main St in the heart of charming & historic Clarence, NY. The community is a beautiful, safe, and family friendly suburb of Buffalo, NY. The entire apt. is on one level, with four parking spaces next to the entrance. The beautiful open concept floor plan provides an abundance of natural lighting, creating a comfortable airy feeling, that is perfect for small gatherings, business travelers, and entertaining.

Cozy Carriage House on Elmwood
Beautiful Airbnb inside a historic carriage house. Located directly on Elmwood Avenue but tucked back & secluded for a peaceful stay. Cozy interior with coffee bar included. The cottage’s prime location is within walking distance to many restaurants, bars, cafes, boutique shops, Delaware Park, the AKG and Birchfield Penney art museums, and more. Off-street parking allows easy access to adventure outside of the village with Niagara Falls & the Bills Stadium just a 20-30 min. drive/Uber away!

Peaceful Walkable 1 Queen Upper AC+parking+laundry
Enjoy this bright & peaceful One bedroom upper apartment located in Buffalo’s happening Westside. Great for long stays! Perfect spot for traveling professionals or couples. The apartment is a 5 min drive to downtown & Buff Gen & 10 min walk to Allen & Elmwood. The Neighborhood is pocketed with many cafes & shops and is one of Buffalo’s Garden Walk highlights. Soak in the historic architecture enjoy & delicious sourdough sandwich made by Breadhive-just a block away! LGBTQ+ POC welcome

The Shecave - 2 Bedroom Apt
This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Upstairs apartment near the airport
Cozy & stylish upstairs apartment in a quiet suburb. Less than three miles from the airport for stress-free travel! Less than one mile from the Walden Galleria Mall, one of the largest in NY state! Less than 10 miles from downtown Buffalo rich in culture, history, art, GREAT food, and night life. 24 miles to Niagara Falls for beautiful hikes and sight seeing. A fun 2 hour road trip to Toronto! Clean & comfortable with everything you need for a short or long-term stay!

Cozy S. Buffalo Retreat - 10 mins to Bills Stadium
Welcome to our beautifully remodeled upstairs studio in South Buffalo! Just 10 minutes from the Buffalo Bills stadium and close to vibrant nightlife, dining, and casinos. Niagara Falls is a scenic 20-minute drive away. The studio features a fully equipped kitchen, a cozy pillow-top queen bed, a living area with a 55" smart TV, an electric fireplace, and a spacious bathroom. Enjoy in-unit laundry and free off-street parking. Experience all the comforts of home!

Clean 2-Bedroom Apt (11 min to DT, 12 to stadium)
Keep it simple yet cozy in our comfortable, centrally-located apartment! This quiet, dead end street is nestled in the center of a vibrant, up and coming part of town. All amenities included - free street parking, WiFi, central heating, and everything you may need to make your stay a good one. We are only 11 minutes from the city, 5 minutes from the thru way, and within walking distance to many restaurants, shops and markets, parks, and a golf course!
Popular amenities for Depew apartment rentals
Weekly apartment rentals

Modern 2-bedroom upper apartment with free parking

Serenity on the Lake - Expansive Lake Views

Buffalo-Area Private Studio

Cozy 2 Bedroom Apt Close 2 Everything

Convenient cozy two bedroom apartment

Peaceful, spacious apartment. Non-smoking.

Shiloh Place: Spacious 3 Bedroom Apartment

Spacious Private Retreat with Kitchen
Private apartment rentals

Cozy & Roomy Apt Close to all

Hamburg village studio 2 within Boots or Hearts!

Centrally Located Comfort Cove

Space, comfort and hospitality!

Cozy place near Airport

Williams Place

South Prince Lower

The Village Cottage Studio
Apartment rentals with a hot tub

Cozy One-bedroom Basement apartment, W/ Hot Tub.

spacious 1 bedroom shared hot tub in the backyard

solar eclipse crash pad!

The River View Condo 1003

Harvest Haven Sunflower Serenity Peaceful & Quiet

Beautiful Parkside apartment.

Luxe, Spacious, Private, Niagara Escape

Modern Oasis Pool & Hot Tub near Buf/Falls/Stadium
Destinations to explore
- New York Vacation rentals
- Tuckahoe Vacation rentals
- Greater Toronto and Hamilton Area Vacation rentals
- Greater Toronto Area Vacation rentals
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- East River Vacation rentals
- Mississauga Vacation rentals
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- Letchworth State Park
- Six Flags Darien Lake
- Holiday Valley Ski Resort
- Niagara Falls State Park
- Niagara Falls
- Buffalo RiverWorks
- Casino Niagara
- Fallsview Indoor Waterpark
- Brock University
- Jackson-Triggs Niagara Estate
- University at Buffalo North Campus
- Seneca Niagara Resort & Casino
- Knox Farm State Park
- Keybank Center
- Vineland Estates Winery
- 13th Street Winery
- Kissing Bridge
- Wayne Gretzky Estates
- MarineLand
- Buffalo Zoo
- Lakeside Park Carousel
- Highmark Stadium
- Genesee Country Village and Museum
- Balls Falls Conservation Area





