Pet-friendly vacation rentals in Cape Girardeau

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Cape Girardeau

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Loft in Perryville

4.97 out of 5 average rating, 268 reviews

Downtown Loft Amazing Bath Tub & Shower

Downtown Perryville, MO **DISCLAIMER** you will hear restaurant chatter & music if you do not have a tv/or radio playing between the hours of 10:30am & 1:30am. If you go to bed early I recommend headphones, ear plugs or play nature sounds on Alexa. This is a pet friendly loft apartment so I would not recommend if you are allergic to dogs or cats. This apartment is located above one of the most popular destination restaurant's around "Mary Jane Burgers & Brew" on the Downtown Historic Square.

Dec 2 – 9

G$29,129 GYD per night

Guest favorite

Farm stay in Fredericktown

4.96 out of 5 average rating, 145 reviews

Spring Valley Ranch Rock House

This quaint farmhouse is located just off of MO Hwy 72 on a 62 acre farm nestled against the Castor River. Here you and your companion(s) can experience the quiet and relaxing life on a farm with plenty of adventure awaiting just around the bend. Sit and enjoy a sip of coffee or tea on the front porch while watching the cattle graze the pasture across the road next to a rustic white barn or venture about 3 miles to the largest privately owned lake in Madison County. Oh yes, enjoy your stay!

Mar 25 – Apr 1

G$24,856 GYD per night

Guest favorite

Apartment in Cape Girardeau

4.94 out of 5 average rating, 173 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Mar 13 – 20

G$25,860 GYD per night

Guest favorite

Barn in Cape Girardeau

4.95 out of 5 average rating, 110 reviews

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built only 2 years ago. Minutes from downtown Cape. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Relax in the front porch rocking chairs, hang out in the vaulted ceiling family area or game loft! Enjoy the sounds of nature around the fire pit, roasting marshmallows and watching the sunset. Near Trail of Tears and walking distance to classic dive bar/burger joint.

Mar 28 – Apr 4

G$44,362 GYD per night

Guest favorite

Place to stay in Makanda

4.93 out of 5 average rating, 160 reviews

Maple Ridge Cabin at Panther’s Rest

Secluded, yet convenient, we’re within 5 min of two wineries, ziplining, trail heads, and I-57. This is your unforgettable romantic wine country retreat or comfortable rest after hiking or travel. There is no TV or Wi-Fi (good cell signal though) but that is not why you’re here! Explore the vineyards, walk the trails, and drink complementary on-farm roasted coffee! Your pet is welcome when you add them to the reservation. Maple Ridge Cabin is your gateway to the Shawnee Wine Country!

Aug 5 – 12

G$28,233 GYD per night

Guest favorite

Home in Cape Girardeau

4.92 out of 5 average rating, 163 reviews

College town Charm: Minutes from Downtown Cape

EXCELLENT LOCATION near downtown riverfront Cape! Enjoy live music, local dining/coffee, shopping, casino, and seasonal steamboat rides downtown. Less than 5 min. from Southeast Missouri State University & Southeast Hospital. Centrally located near wedding venues: Rusted Route, Deerfield, Watersedge, Sweet Pecan, and Country Club. 2 blocks from scenic Capaha Park. Home to Capaha baseball. This huge park includes play structures, basketball court, disc golf & fishing pond.

May 4 – 9

G$21,065 GYD per night

Guest favorite

Cottage in Vienna

4.96 out of 5 average rating, 140 reviews

Peaceful Cottage Retreat

Contactless Check-in. This cottage has everything you need for a relaxing getaway. It's private, tranquil setting is surrounded by nature. A queen bed with luxury bedding ensures a peaceful stay. The cottage comfortably accommodates 4 adults with the additional sleeper sofa. The kitchen includes a mini-fridge, microwave, toaster and coffeemaker. A cozy gas fireplace inside, and the large patio, gas grill, wood burning firepit, and a shady hammock compliment the outdoor space.

Jun 16 – 23

G$24,255 GYD per night

Superhost

Cabin in Bloomsdale

4.86 out of 5 average rating, 249 reviews

Getaway St. Francois - St. Louis

An easy drive from the city, Getaway is a new way to experience the great outdoors. Nestled across dozens of acres of private woodlands, our modern, tiny cabins have everything you need (comfy bed, bathroom, fresh linens) and nothing you don’t. Featuring a private outdoor area (hello, fire pit), each cabin is designed to help you relax, unwind and disconnect from the everyday. Plus, as part of your stay, you'll receive firewood, a s'mores kit, coffee and bottled water*.

Jul 17 – 24

G$26,992 GYD per night

Guest favorite

Treehouse in Makanda

4.97 out of 5 average rating, 183 reviews

Panthers Inn Treehouse

Come nestle amongst the leaves at Panthers Inn Treehouse. This secluded, well equipped, elevated cabin has the perfect combination of natural beauty and artful luxury. Isolated yet conveniently located 2 minutes from Blue Sky and Feather Hill wineries, within 5 minutes of Panthers Den hiking trail and the Shawnee Hills canopy tour and only 10 min from I-57 exit 40. Panthers Inn is the perfect starting and ending point to your Shawnee Hills Wine Country vacation!

Feb 26 – Mar 5

G$32,700 GYD per night

Guest favorite

Place to stay in Cobden

4.95 out of 5 average rating, 272 reviews

Private Retreat Cabin - Southernmost, IL

A private retreat space, Eva’s Roost is located at Center For Lost Arts near Cobden, Illinois. Uniquely crafted rustic, zen-style cottage, designed to be close to the earth & nature. Extensive, curtainless windows facing the forest & pond allow for private views: sunrise, moonrise, forest & wildlife. Yoga mat, guitar & some art supplies. Personal outdoor space with firepit & comfy adirondack chairs. Entrance to wandering trails right outside your back door.

May 28 – Jun 4

G$23,439 GYD per night

Guest favorite

Loft in Cape Girardeau

4.9 out of 5 average rating, 188 reviews

Riverwalk Loft 3

Historical building with modern amenities. We are located right in the middle of downtown life. With the excitement there will come noise from bars, live bands, and the occasional train. If you love staying where fun is happening, this ones for you. Please note: we are located above an arcade bar and you are a building up from the River wall. There is also a currently operational TRAIN track with TRAINS, that make TRAIN noises 200ft from our lofts.

Jul 17 – 24

G$28,091 GYD per night

Guest favorite

Tiny home in Whittington

4.94 out of 5 average rating, 125 reviews

Tiny Home of Whittington

This cozy tiny home is located a little over one mile off of Interstate 57 and within two miles of Rend Lake. Whether traveling through and needing an easy one night stay or a weekend getaway, this is the place for you. Located in the quiet village of Whittington, the property has great access to the area while providing a peaceful stay on the edge of the country. There is plenty of parking space for anyone traveling with a pickup and trailer.

Jan 25 – Feb 1

G$14,929 GYD per night