Apartment vacation rentals in Cape Girardeau

A view from the front porch showcases a vibrant autumn scene, with trees covered in golden leaves. A cozy seating area is visible, framed by white railings, and a peaceful street with fallen leaves creates a calm atmosphere.

4.98 out of 5 average rating, 414 reviews

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.

4.95 out of 5 average rating, 244 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

4.96 out of 5 average rating, 45 reviews

A view from above captures the full kitchen equipped with electric appliances, including a refrigerator and stovetop. The wooden floor is complemented by colorful area rugs, and natural light brightens the space. Shelves and cabinetry are neatly arranged in the background.

Apartment in Carbondale

Regal Rustic Retreat

Take it easy at this unique and tranquil getaway. Close to SIU Carbondale and also Murphysboro. We offer a quiet, simple apartment to relax and recharge. Free local over the air television. We have broadband/smart monitor for your HDMI stick . Bring your own Roku or Firestick with your subscriptions. The second bedroom is an open loft area, not a separate room. We offer a large storage space for bicycles and mudroom with washer/dryer for cleaning up after a hike or bike race. Full kitchen.

The building features classic brick architecture with ornate ironwork detailing on the balcony. A large clock is positioned on the exterior wall. Nearby streets and parked vehicles are visible, along with a clear blue sky providing a bright backdrop.

4.98 out of 5 average rating, 95 reviews

Historical Kage House

The Building is reminiscent of eighteenth-century New Orleans architecture, and was built sometime before 1883. The Kage House is located at 120 Broadway in the historical district and is less than a minutes walk to Main Street and less than a 10 minutes walk to the Isle of Capri Casino. On Main Street you will find many fine shops and restaurants, or just enjoy the scenic area as you walkabout. This is by far one of the best places in Cape. Additional reviews can be read on the VRBO website.

A spacious dining area is seen with a glass table surrounded by light blue chairs. A stylish chandelier hangs overhead, illuminating the space. Decor includes a large area rug and decorative elements, while bicycles are parked nearby, hinting at an outdoor adventure option.

4.86 out of 5 average rating, 606 reviews

Unique Design | Walk Downtown/River | .5 mile SEMO

At our Adventurous 2 Bedroom Suite you’ll first arrive at a Brightly decorated Space with Artsy Walls and Bold Decor. Designed with its History in mind & a twist of Creativity, you will Immerse Yourself within your Stay; from our Stocked Kitchen, Reading Area with Indoor Swing to Themed & Cozy Bedrooms. Enjoy being near Downtown/the River with a short Bike Ride or Walk and when you are ready to Tuck in at night, Sink into our 10” Memory Foam mattress with Plush Pillows and feel at Ease.

4.95 out of 5 average rating, 43 reviews

A serene view of the Mississippi River is presented, highlighting the tranquil water and the pavilion that juts into the river. Lush green grass borders the water, and trees line the distant shore, creating a natural landscape under a clear sky.

Apartment in Scott City

RiverSide Barn Suite on the Mississippi River.

The barn suite is a beautiful 2 bedroom apartment overlooking the Mississippi River and housed in a unique barn with its own separate entrance. The deck views are spectacular and takes sitting and relaxing to a new level. Our wine place “The RiverHouse “ is within walking distance with the best worldwide wines and menu in the area. www.theriverhousewineplace.com We are 12 minutes from Cape Girardeau and serviced by Lyft & Car-Go. You May contact us by text or call and available at any time.

A modern kitchen showcases stainless steel appliances and a spacious island with bar seating. The sleeping area features a metal-framed bed and exposed brick walls, enhancing the cozy ambiance. A well-furnished living area includes soft seating and a decorative plant, offering a comfortable gathering space.

4.78 out of 5 average rating, 23 reviews

Modern Luxe 2 KBR Apt w/ Electric Fireplace

Experience luxury living in the heart of downtown Cape Girardeau right on Broadway with this stunning apartment nestled above the beautifully rehabbed Broadway Theater. Features spacious, open-concept layout with high-end finishes throughout! Enjoy cozy living spaces complete with electric fireplaces. Located on iconic Broadway Street, you’ll have direct access to shopping, dining, and downtown events, making this a prime oasis. Complete with a bourbon lounge below and bistro next door!

A spacious roof deck is highlighted, featuring a wooden surface and metal railing. Two woven chairs and a small table are positioned to allow for relaxing moments while enjoying expansive views of the river and surrounding greenery.

4.97 out of 5 average rating, 143 reviews

Downtown Penthouse w/ Amazing River View!

AMAZING RIVERVIEW Plus Close to Downtown Cape? Our Airbnb is the best place to be! Relax in our Roof Deck after going around downtown and ENJOY THE VIEW. Located in a safe and quiet neighborhood plus it is WALKING DISTANCE from everything! It features a roof deck with (by far) the best view in Cape, enough space for six to sleep (two queen beds and two couches), one off street parking spot and a building with secure entry. Plus we just live across the street if you need anything.

The entrance features a welcoming front porch with a white bench and colorful flower pots. A vibrant arrangement of yellow daffodils blooms along the walkway, enhancing the inviting appearance of the home. The exterior is characterized by a combination of white brick and gray siding.

4.88 out of 5 average rating, 100 reviews

Visit the "Gone Girl" neighborhood

Living rm/bedrm, full kitchen, ADA bath, and walk in closet. Fully equipped with dishes,linens, refig, micro,stove, keurig, dishwasher and welcome home snacks. Double Murphy bed, queen hide a bed couch convert the living room to bedroom. Space is good for up to 3 adults, 2 adults and 2 children or a single guest. We accept well mannered dogs up to 50 pounds. We do not accept CATS. Like cats but they cause additional clean up. See pets section for dog guest guidelines.

A spacious living area features dark hardwood floors and light gray walls, accented by a comfortable leather sofa and an elegant coffee table. Artwork adorns the walls, and natural light streams in from the nearby windows, illuminating the inviting space.

4.93 out of 5 average rating, 41 reviews

Downtown 4BR with 2 King Beds! Off-street parking

- Massive two story 2,400 sq ft historic apartment on Broadway - Recently renovated - Downtown location - Free off-street parking - Walking distance to SEMO and River Front - 2 King beds! - 3 Bathrooms - 2 futons and one couch for extra sleepers - Self check-in with smart lock - Full kitchen - Washer/Dryer included - Formal dining area - Second cozy living room upstairs - Room darkening shades in all bedrooms - Note: narrow staircase at entrance

An open-concept living area features a spacious leather sectional couch, a round coffee table, and a dining area with sleek pendant lighting. Natural light pours in through large windows, highlighting the exposed brick walls and modern appliances in the kitchen.

4.82 out of 5 average rating, 51 reviews

Downtown Cape 2 Bdrm/2 Bath Apt | Cozy & Walkable

Experience style and convenience in this new, cozy, fully outfitted central apartment. Enjoy your privacy while being right in the heart of downtown Cape Girardeau! You’ll be seconds away from great restaurants, bars, shops, and more! A great stay for both short-term and mid-term stays! - King-size bed - Dedicated workspace + highspeed wifi - Fully equipped kitchen - Laundry machine in unit - Free parking - Walkable area, near trails and park

The living room features comfortable seating for four and a bay window providing natural light. A SmartTV is mounted on the wall, with a cozy fireplace ambiance displayed. Decorative plants and framed artwork enhance the welcoming environment, inviting relaxation.

5 out of 5 average rating, 3 reviews

Rivers Dawn- Historic Home - River View - King Bed

This cozy upstairs loft is just steps from Downtown Cape Girardeau, offering stunning views of the Mississippi River, Bill Emerson Memorial Bridge, and historic district homes. Enjoy peace and quiet, with the vibrancy of downtown just a short walk away. Perfect for those seeking a relaxing retreat with easy access to the area's best attractions. Ideal for both relaxation and exploration!

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Popular amenities for Cape Girardeau apartment rentals

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Free parking on premises

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Weekly apartment rentals

A view from the window captures the vibrant streetscape of downtown Cape Girardeau, featuring a mural on the adjacent building and a glimpse of the river beyond. Decorative street lamps line the sidewalk, contributing to the lively atmosphere.

4.84 out of 5 average rating, 37 reviews

Gail's Corner Window- River View

BarbaraRating, 5 stars7 months ago

Exactly as described! great location and beautiful views

A charming cabin features a covered porch with seating options, including two rocking chairs and a turquoise bench. The exterior is framed by lush greenery, creating a serene atmosphere. A welcome sign is displayed above the door, inviting guests to enjoy the surroundings.

Apartment in Tamms

4.74 out of 5 average rating, 19 reviews

Cabin in the woods perfect for hiking

HaleyRating, 5 stars13 months ago

Tammy was fantastic and kind. The place was great for a weekend of turkey hunting and close enough to get to the city to shop and find other things to do as well. We would stay again.

A calming saltwater pool is surrounded by a black metal fence, with a vibrant tree providing shade nearby. The pool area features an inviting blue hue, contrasting with the warm tones of the adjacent landscaping and architecture.

KyleRating, 5 stars6 months ago

Location, Location, Location!

Jay wallpaper friendly and ready to help in any way possible during the stay. The residence was very clean and kept upon arrival and ccommunication with Jay was always very easy.

A comfortable living area features a neutral-toned sofa with decorative pillows, positioned near a window with sheer curtains. Two floral artworks are displayed on the wall, while a soft area rug lies on the floor. A side table with a lamp adds functionality to the space.

Apartment in Marble Hill

4.63 out of 5 average rating, 8 reviews

Lutesville Villa

MargaretRating, 5 stars2 months ago

We really enjoyed our stay. The place was clean and the host was very responsive. It was very quiet .

A well-equipped kitchen area features light wood cabinetry, a white refrigerator, and a stove/oven combination. A round dining table with four brown chairs is centered in the space, while large windows provide natural light and access to an outdoor entrance.

4.82 out of 5 average rating, 22 reviews

Murphysboro Retreat w/ Deck Near Kinkaid Lake!

LarryRating, 5 stars2 weeks ago

Our host was there to greet us, very pleasant. Otherwise we had total privacy. The unit is very clean with everything we needed. Wi-fi, streaming, comfy couch and bed, pleasant deck, restful. Nicely appointed bathroom with lots of hot water. We hope to book for our next visit to the area! Thank you, JJ.

A modern living space features a dark velvet sofa adorned with yellow accent pillows. A small yellow coffee table sits in front, while a clock is mounted on the wall above. A side chair in bright yellow adds a pop of color, with natural light filtering through the window.

4.85 out of 5 average rating, 26 reviews

The Lab! Come stay in our brand new space.

EbonaeRating, 5 stars1 month ago

Would definitely stay again if in the area.

A modern bedroom is presented with a black queen size bed dressed in a leopard print duvet. Two matching pillows coordinate with the bedding. A mirrored dresser reflects the decor, including a framed floral artwork and a small vase of colorful flowers placed on the side.

Apartment in Carbondale

4.52 out of 5 average rating, 102 reviews

Extended stay DownTown Carbondale

AlanRating, 5 stars2 months ago

Central location in CDL, walk from train station. Can walk to all services, grocery, laundry, etc.. Nice cafes, PK's bar (much character!), Harbaugh's, Italian Village with its terrace. Varsity Center theater always something on. Kitchen well fixtured. Shower works great. Bed very comfortable. Apartment is in the back of the building. Very satisfactory stay for work in the town.

A comfortable living area features a light gray sofa and a dark recliner, arranged around a black coffee table. A patterned area rug adds warmth to the wooden floor. Framed artwork is displayed on the wall, complemented by soft lighting from ceiling fixtures.

4.67 out of 5 average rating, 3 reviews

Downtown Retreat

HelamanRating, 5 stars1 month ago

Dustin’s place was spacious and clean. Fit really well for our needs. Highly recommend this place. Will be returning whenever we’re back in town.

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Private apartment rentals

The open-concept living area showcases an exposed brick wall, enhancing the character of the space. Natural light fills the room through large windows. A comfortable sofa is positioned near a sleek coffee table, with a wall-mounted TV visible. A kitchen equipped with modern appliances is in the background.

5 out of 5 average rating, 5 reviews

2Bdrm Stay in Downtown Cape | Walkable, Laundry

MalloryRating, 5 stars3 weeks ago

We came to Cape for a quick getaway weekend from STL. Lindsey’s place was perfect for the 2 of us. Kitchen was well stocked with cooking gear but we did not use them! Beds were super comfortable!! My only real complaint is how loud the noise from the street is. Might have just been situational as I heard from many people that the college kids were all having their last hurrah but there were many many cars revving engines and squealing tires right outside the building until about 2AM. Lindsey was a fab host and we will book with her again if we ever come back to Cape!

A cozy living area showcases a plush sofa paired with two armchairs. A modern workspace with a desk and chair is highlighted, along with a Smart HDTV displaying Netflix. The bedroom features a spacious bed, accented by natural light filtering through multiple windows.

4.92 out of 5 average rating, 24 reviews

Cozy Boho 2KBR Apt w/ Electric Fireplace

JulieRating, 5 stars2 weeks ago

Grace was exceptional as a host, very responsive. Beautiful apartment with everything needed for my stay. Would definitely recommend staying here.

The entrance features a dark door set beneath a small overhang, with a decorative wall accent to the side. A welcome mat is placed in front of the door, while greenery is positioned nearby, enhancing the welcoming appearance of the entrance.

StevenRating, 5 stars14 months ago

INN Keepers Quarters

Rae has a very cute but small 2 bedroom bungalow in the center of Murphysboro. The master bedroom is large though and very comfortable with a great bed. The second bedroom has a smallish bed/cot not as comfortable. If you’re sensitive to light in the morning this place might not be the best because the windows are not fully covered. All in all a very nice, clean place in a great part of town

A rustic two-story building is surrounded by a grassy area with colorful Adirondack chairs in red, orange, and purple arranged around a black firepit. The weathered exterior of the building complements the natural setting, framed by tall trees in the background.

4.86 out of 5 average rating, 29 reviews

Lake front getaway for 2!

KimberlyRating, 5 stars8 months ago

Ashley and her lakefront rental were both amazing! She made check in and out so seamless and easy , place was juys wayt we needed As makanda girl I really enjoyed the peaceful private yet safe neighborhood feel a lot It was wonderful to sit on that bench and watch the sunset over the lake and was so serene Hope to stay there again sometime Ashley was great

5 out of 5 average rating, 7 reviews

An open-concept living area showcases a light-colored sofa and an oversized ottoman, complemented by two accent chairs. A gallery wall adorned with framed artwork adds character. The kitchen is visible in the background, featuring modern appliances and a large island with seating.

Apartment in Carterville

Downtown Loft with full kitchen and laundry room

JaredRating, 5 stars4 days ago

Nice place! The kitchen had everything you needed to cook a meal. The place was very clean. Easy check in and it was easy to find. I would definitely stay again!

The image showcases a blend of living and outdoor spaces within the studio. A spacious seating area features a plush sofa and a cozy bed, while a separate dining area is visible in the background next to an inviting bar. Outdoor seating is arranged on a patio, surrounded by greenery.

5 out of 5 average rating, 14 reviews

Downtown Studio Apt | King Bed & Full Kitchen

AnthonyRating, 5 stars1 month ago

very kind and understanding person that very quickly helped fix my mistakes for not reading thoroughly. perfect host.

A cozy living room features a green-tiled antique fireplace with a marble hearth. Plush seating for four is arranged on a decorative rug, while natural light filters in through large windows. A dining room is visible through an open doorway, showcasing a table with elegant seating.

4.67 out of 5 average rating, 3 reviews

Rivers Dusk- Historic Home - River View - King Bed

WendyRating, 5 stars15 months ago

The house was exactly like it was described. Is absolutely beautiful. The beds were so comfortable we were looking forward to going to bed right after waking up! We visited on a girls trip. There were four of us and we all fit comfortably. The living room is large and had enough seating for us to all spread out and watch movies on the smart tv. Bathroom was also big enough for all four of us to do hair at the same time. (The large mirror in the king bedroom was also helpful for that.) The house is just a couple blocks down from the main area where all the shops and restaurants are. We could have walked if we wanted to. Definitely recommend! Amber was very helpful and communicative.