
Vacation rentals in Cape Girardeau
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Top-rated vacation rentals in Cape Girardeau
Guests agree: these stays are highly rated for location, cleanliness, and more.

Cozy 1-BR guest house w/free parking on premises
Enjoy a cozy experience at this centrally, located place. Literally, a 1-4 minute walk to Mercy Hospital(formerly Southeast Hospital), less than 1 mile to Southeast University Campus, along with downtown(river). A street over is Broadway with many restaurants. Walmart Market and Dollar General are also conveniently located nearby. The kitchen is fully furnished with cooking utensils, clean towels, pots and pans for those who prefer eating in. Please no animals and no smoking in the apartment.

Ma's Cabin, Alto Pass, IL. Fine country lodging.
Cute and country remodel done in 2019. Recent new appliances, furnishings, flooring, heat & A/C, washer & dryer. Cabin is secluded and quiet plus 1/2 mile from Alto Pass Lookout Point and right in the middle of many award-winning wineries. 15 miles from Carbondale 4 miles from Giant City 30 miles from Garden of the Gods 6 lakes within 10-mile radius Hundreds of miles of hiking trails in nearby Shawnee National Forest 6 miles from Bald Knob Cross Please, no dogs! No smoking in cabin!

Beautiful Historic Boulevard District Apartment
This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

MAINSTAY CAPE [downtown]
Nestled in the heart of the Downtown Historic District, this suite is centrally located as a prime destination for any and all travelers alike. With parking available, this space offers a unique & trendy “midwest boho” vibe. ~WALKABLE~ Our studio is 1 block from the bustling Southeast Missouri State University, 1 block from the gorgeous Capaha Park, and 2 blocks from Mercy Hospital. If you are interested in night life, this space is simply a 5-10 minute walk to all DT bars and restaurants.

Brand new 2 bedroom unit right in downtown Cape.
This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Historical Kage House
The Building is reminiscent of eighteenth-century New Orleans architecture, and was built sometime before 1883. The Kage House is located at 120 Broadway in the historical district and is less than a minutes walk to Main Street and less than a 10 minutes walk to the Isle of Capri Casino. On Main Street you will find many fine shops and restaurants, or just enjoy the scenic area as you walkabout. This is by far one of the best places in Cape. Additional reviews can be read on the VRBO website.

Twisted Sassafras Treehouse
A custom-built treehouse located on 10 acres with a water view that you can take in from the hot tub on the deck! It is nestled high in the trees and is the perfect romantic getaway for two! Feel like you are away from it all without being away from it all! This treehouse is located on a county road just minutes from Cape Girardeau. Enjoy catch and release fishing on site, local wineries, shopping in historic downtown Cape Girardeau, local restaurants, gambling, historical sites & more!

Private two room suite in downtown Cape Girardeau
Spacious two room suite with a queen size bed in one room along with a single bed and a futon sofa in the other room. Private full bathroom. Kid friendly. Refrigerator with drinks available. Separate heating and cooling control. Cathedral ceiling. Located in a good neighborhood. Walking distance to downtown, riverfront, restaurants, and musical venues such as the university River Campus. A wide porch and large goldfish pond are in front. The suite is on the second level of the home.

Under the Stars - Farmhouse
Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

Downtown Guesthouse- Romantic Getaway
The guesthouse seamlessly blends modern amenities with historic charm in a cozy, compact space. The antique claw foot tub/shower combo offers a charming, yet snug, spot for a relaxing soak—true to its historic roots, the bathroom could be best described as a quaint water closet. After a day of exploring unwind in the patio. Play a favorite record, and savor your coffee while daydreaming about new experiences. Despite its small size, it provides all the modern comforts you need.

Log Cabin w/ Hot tub - Near Casino & Downtown Cape
THE BEST GETAWAY HERE IN CAPE! Have a relaxing staycation here in Cape Girardeau Perfect for a QUICK GETAWAY for couples, families or friends 5 MINS to the casino, country club and downtown cape Very unique log home with a private bedroom queen size bed, pull-out queen size futon in the living room and twin size hide away SLEEPS 4. Pool table, darts, and a hot tub.There is a large deck and fire pit which has the feel of being in the woods.

Downtown loft, walk to all the action, charming
This rental is in the heart of downtown Cape with all the restaurants, nightlife and shopping at your leisure. It is an airy upper unit on the corner of Themis and Spanish streets just one block from the mighty Mississippi. The owner's law office is housed on the main level. Included is king size bed, queen pull out couch, full size futon, and queen air mattress. Come and relax on the spacious deck and enjoy the local flair.
Popular amenities for Cape Girardeau vacation rentals
Other great vacation rentals in Cape Girardeau

The Cabin at Timber Creek

Cute Purple Tiny House in Tiny Home Village

Historic Victorian-Walk to Downtown Cape-King Bed

[*Charming Cozy Suite*]

Happy home for traveling professionals

The White House, Located Near SEMO. Historical Gem

Located near downtown and casino

Boho Chic
When is the best time to visit Cape Girardeau?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$25,059 GYD | G$23,806 GYD | G$23,597 GYD | G$25,059 GYD | G$25,685 GYD | G$25,894 GYD | G$26,103 GYD | G$25,059 GYD | G$25,059 GYD | G$25,059 GYD | G$25,059 GYD | G$24,432 GYD |
| Avg. temp | 1°C | 4°C | 9°C | 14°C | 20°C | 25°C | 26°C | 25°C | 21°C | 15°C | 8°C | 3°C |
Frequently Asked Questions
Are there vacation rentals with a dedicated workspace in Cape Girardeau?
Yes! Work meets play with ease at over 80 vacation rentals in Cape Girardeau featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there pet-friendly vacation rentals in Cape Girardeau?
Four-legged friends are welcome in Cape Girardeau. Choose from more than 50 vacation rentals for guests traveling with pets.
Do house rentals in Cape Girardeau have wifi?
Absolutely! We offer over 70 house rentals with wifi in Cape Girardeau. Enjoy a tailored experience with all the comforts you desire.
How much does it cost to stay in apartment rentals in Cape Girardeau?
Experience the best of Cape Girardeau with our apartment rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Are there family-friendly apartment rentals in Cape Girardeau?
Cape Girardeau has more than 20 family-friendly apartment rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do house rentals in Cape Girardeau have a bbq area?
Absolutely! We offer over 10 house rentals with a bbq area in Cape Girardeau. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Cape Girardeau have air conditioning?
Absolutely! We offer over 70 house rentals with air conditioning in Cape Girardeau. Enjoy a tailored experience with all the comforts you desire.
What are the most popular amenities for House Rentals in Cape Girardeau?
Enhance your stay in our House Rentals with the most popular amenities: over 70 homes with wifi, over 70 homes with air conditioning, over 10 homes with a bbq area, and more. Indulge in the ultimate retreat, tailored to your preferences.
Quick stats about vacation rentals in Cape Girardeau

Total vacation rentals
Explore 150 vacation rentals in Cape Girardeau

Nightly prices starting at
Cape Girardeau vacation rentals start at G$6,265 GYD per night before taxes and fees

Verified guest reviews
Over 8,880 verified reviews to help you choose

Family-friendly vacation rentals
80 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 40 rentals that welcome pets

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
150 of Cape Girardeau vacation rentals include wi-fi access

Popular amenities for guests
Guests love Gym, BBQ grill, and Laptop-friendly workspace across Cape Girardeau rentals

4.8 Average rating
Cape Girardeau stays are highly rated by guests—averaging 4.8 out of 5!
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