
Guesthouse vacation rentals in Anderson County
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Top-rated guesthouse rentals in Anderson County
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Family-friendly guest house rentals

Holly Hideaway! 10 Highway miles to Clemson U!
Jen’s Hideaway is the perfect private spot to come back to after visiting Central and Clemson. It is extremely clean and well appointed. The bed is very comfortable. Jen is a friendly host. She even baked us delicious blueberry muffins.

La Bella Farm
Had an amazing time at this gorgeous space. It was exactly as advertised, and Jessica was extremely responsive and proactive as a host. Thank you so much! Will definitely book there again!

South Oaks Guesthouse
Diane’s home is lovely! T It was relaxing, comfortable and welcoming! We will stay again!

Home on the farm
This was our 3rd time there. It is the most relaxing place to stay. Ruth thinks of everything, you don’t want for anything. You will not find any better hosts than Ruth and Bob. We absolutely love our stays, have stayed in both the apartment and the cabin and we’ve been extremely happy in both. If we could live there we would! I highly recommend staying in either place. Ruth is the sweetest person you will ever meet and makes you feel like family.

Lisa’s Lodge
Lisa's Lodge was wonderful; just perfect for the two of us. It was so nice to take a dip in the lovely pool, sit by the the beautiful lake and take walks around the grounds and up the road. Proximity to Anderson yielded a couple of good restaurants and it was also an easy trip to Greenville and its charms. Lisa is very nice and her son offered help in case we needed it during a rainstorm. What a happy experience! We both want to go back!
Guest house rentals with a patio

One Particular Cove ... on Lake Hartwell
We couldn’t be happier with our stay. Perfect size for the 4 of us. Ginny and Sid are wonderful hosts. Our flight was changed and delayed and we didn’t arrive till 3am and had to leave for Clemson graduation by 730am. With little to no time to sleep or eat breakfast they stocked the place with fresh pastries, fruit and bagels and cream cheese. We sadly were only to spend nights at the property so we did t get a chance to take the whole lake location in. I’d go back in a heartbeat

Charming Waterfront Guest House
Beth’s place is amazing. We have stayed here before and loved it so much we came back to stay again. It’s a beautiful house on the water with a pristine guest house that’s private, extremely clean, and very well maintained. Beth is incredibly friendly and always a great communicator. Would highly recommend, 10/10. Thanks Beth!

Downtown Clemson Guest Suite!
The studio was adorable! Great location, clean, new and perfect for our stay in Clemson. There were only two of us but, plenty of room. I only wish I had found it before graduation. I will definintely look to reserve again when we head down for games. Great communication from Casey!

Adorable Cottage 2 mi. from Death Valley
Clean, peaceful, great location to the campus. Hosts are friendly and kind. My second stay and I can’t wait to go back.

The Honey Flat
My husband and I stayed at Holly's place to attend the wedding of our granddaughter who was married in Honea Path and reception in Due West..the location was very good for all the activities involved. The house was perfect for us as it had everything we needed for our stay..We enjoyed the chickens, pigs and dogs on the property. Would definitely stay there again if the occasion arises. Delores and Reid Lowery..Shelby NC

Vacation Home Clemson and Lakes
We had a wonderful stay in this beautiful home for our Tiger's graduation from Clemson. The home was extremely clean and well stocked with everything we needed. We enjoyed the backyard and patio as well. The host was friendly and responsive.

Shou-Sugi-Ban Retreat on the Saluda River
Surprise last minute Father’s Day mountain get away for my husband. This home was perfect for the three of us. Adorable, Clean and a spa shower! We enjoyed hanging on the deck with our dog listening to the river rapid (minus some traffic noise) and just chilling all night and morning! Delicious coffee! Quick trip home to the beach rested and grateful for unplugging! We would certainly would love to come back! **The lightning bugs were a huge bonus!

Quin's Lake House, Keowee. Private bottom Floor.
This is a beautiful place to stay on the water. Owner is continuing to make updates to make the stay easier particularly in the kitchen area.
Guest house rentals with a washer and dryer

Quaint guest cottage in Upstate
Not our first stay at The Canning House and not our last! We love the country feel and the rain on the tin roof. It was so nice to wake up and see the cows out back in the pasture (took some pics there) and hearing the birds chirping. See you another time for sure!

The Cottage at Keowee Hollow
We absolutely love The Cottage. It was close enough to my grandson’s graduation festivities in Clemson. It was so clean and private and we will definitely use it again on our next trip to the area.

Paradise Point on Lake Hartwell
This place really is a Paradise! The dock and the area by the lake are amazingly pretty and peaceful. We enjoyed fishing (caught brim and catfish), sunbathing, and relaxing by the water. We brought our own boat and that went really well. The boat launch was nearby and we were able to take the boat to a fun restaurant called The Grill. The guesthouse was clean and cozy. We had 7 adults and there was plenty of room. The rec building gave some extra space to hang out, play ping pong, and watch a movie. The guys enjoyed playing basketball and pickle ball on the outdoor court. The kitchen had all of the basics and we used the outdoor gas grill. Overall it was just a really fun family weekend at the lake and we would definitely recommend this place!

Clemson Carriage House - NEW!
Ashley‘s carriage house was such a cute place to stay. It is very central in Clemson to everything you would need to go to and was perfect to attend an event in Clemson. Is extremely clean and I especially loved all the Clemson Tiger touches in decor. I would stay here again if I came back for a Clemson game!

Hartwell Hideway
I had such a wonderful stay at this spot on Lake Hartwell! The place was cozy, clean, and had everything I needed for a relaxing escape. The bed was very comfortable. The lake itself was incredibly peaceful—perfect for morning coffee on the deck or evening kayaking sessions. I loved having easy access to the water. What made the trip even better were the hosts—they were so helpful, responsive, and genuinely friendly. They went above and beyond to make sure I felt welcome and comfortable throughout our stay. If you’re looking for a quiet, nature-filled retreat with thoughtful hosts and easy lake access, this is the spot. I can’t wait to come back!

Beautiful Luxury home on Lake Hartwell by Clemson
Great place & location for peace and sound. Would highly recommend to stay there again.

Riggs Drive Gameday Getaway
Really nice space walkable to downtown but on a quiet street. The space looks brand new, well designed and appointed. High ceiling ls and very open feel. Everything is high quality and very clean. We will definitely stay here when in the area
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