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House vacation rentals in Anderson County

Find and book unique houses on Airbnb

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Popular amenities for Anderson County house rentals

House rentals with a pool

Top guest favorite
A brick ranch-style home is set in a spacious lawn, surrounded by neatly trimmed bushes and trees. The house features a symmetrical facade with white shutters framing the windows and a welcoming front door. A driveway leads to a garage on the side.
Home in Mauldin
5 out of 5 average rating, 51 reviews

Upstate Getaway at the Relaxing Ranch

LeeRating, 5 stars2 weeks ago
We travel with 2 small chihuahuas and a secure fence is very important to us. It was very secure and we didn’t have to worry about the dogs escaping the huge back yard at all. Cristina thought of everything. The home was well stocked with all the essentials and more organized than our own house. Haha. Perfect, relaxing place to stay.
A fenced pool area is viewed under a sunset sky, showcasing a clear blue pool surrounded by patio stones. Lounge chairs are placed around the pool, and an umbrella provides shade. Nearby, inflatable pool toys rest on the edge, amidst greenery.
Home in Pendleton
4.67 out of 5 average rating, 18 reviews

The Hawks Nest

BridgetRating, 5 stars9 months ago
Exactly what I was looking for! I was in-town for parent's weekend and looking for a place with a great kitchen to prepare home cooked meals for my daughters as well as great location. Instantly felt like home and we knew an amazing family lived there. The host went out of her way to make sure we were comfortable and had everything we expected. I hope it is available for my future trips!!
An aerial view showcases a spacious home surrounded by lush greenery, with a landscaped gunite pool featuring a curved shape nearby. A covered deck offers additional outdoor space, contributing to the serene atmosphere of the property.
Home in Anderson
4.96 out of 5 average rating, 23 reviews

Beautifully updated waterfront Lake Hartwell home

AdrienneRating, 5 starstoday
This was the PERFECT location for our family vacation! We have a family of eight with two married couples, a 17 year old, and an 8 year old. There was plenty of space and lots of extras to keep everyone busy. Marie’s place felt like home which made it easy to enjoy and relax. She was also very communicative and helpful any time we had a question. Anderson is such a sweet little city. Several good local eats, a precious downtown area, and the nicest Chick-fil-a workers ever! We look forward to visiting again!
Superhost
The outdoor pool area features light blue water, with children playing near a colorful beach ball. Surrounding the pool are well-kept lawns and landscape shrubbery. The condo buildings rise in the background, displaying a rustic charm with wooden facades and green roofs.
Home in Six Mile
4.87 out of 5 average rating, 39 reviews

Lake Keowee Access-Dock-Pool-Grill-Clemson 17 Min

JeffRating, 5 stars4 days ago
The condo was well maintained and extremely clean. What we liked most was being outside of the city with beautiful drives in any direction. We visited Greenville, SC for a day, spent a day renting a boat on Lake Jocassee, and took a drive another day to Gorges State Park for some hiking. Everything was within an hours drive and the towns of Senaca and Clemson had anything you might need supply wise. The pool was clean and landscaping kept nice and trim. Erin was a wonderful, super responsive, host. I would highly recommend staying here.
Guest favorite
Aerial view of a spacious home featuring a private pool surrounded by lounge chairs, a pool deck, and an outdoor sitting area. Lush green trees and a fenced yard are visible, enhancing the outdoor space. The property provides access to the surrounding neighborhood.
Home in Seneca
4.94 out of 5 average rating, 36 reviews

Keowee Lakeside with pool for 16

LauraRating, 5 stars5 months ago
Tyler’s place was nice and comfortable. Clean beds and couches. We had a large group. My sisters and I planned on cooking daily. When I notified Tyler that one of the burners was not working he sent a maintenance employee to check it out. A new stove was installed for us to use. The children enjoyed riding their bikes in the neighborhood and wanted to get in the pool but it was too cold. We have to plan another trip. Christmas was fun at this house . Thank you Tyler for being such an awesome and responsive host!
A cozy living space features a modern fireplace and a large flat-screen TV mounted above. Light streams through expansive glass doors, revealing a private deck. Comfortable seating is arranged around a wooden coffee table, enhancing the inviting atmosphere of the room.
Home in Salem
4.74 out of 5 average rating, 27 reviews

* Keowee Key* Lake* Fireplace*Golf*Tennis*Gym*

Elisa SuttiRating, 5 stars2 months ago
Christina's house is amazing! We had a wonderful week in her home. It is spacious, comfortable and very clean. Equipped with all the necessary comforts and more. It also has a very large terrace. I highly recommend it!!
An open floor plan is displayed, featuring a large, light wood dining table surrounded by six chairs. The kitchen area presents wooden cabinetry and stainless steel appliances. Natural light enters through multiple windows, with a decorative cabinet positioned against a wall, contributing to the spacious ambiance.
Home in Seneca
4.67 out of 5 average rating, 3 reviews

Lake house 8 mi. to Clemson stadium vacation home

MandyRating, 5 stars3 days ago
Beautiful home and area. Nice relaxing pool and hot tub. Home was homey and felt very relaxed. Bed was comfy and slept well. Very nice getaway.. Hosts ARE AMAZING!!! MUST STAY AT THIS HOUSE....
Top guest favorite
A serene outdoor area features a landscaped pool surrounded by natural stones and lush greenery. Several seating areas are available, including a decorated table and chairs. A thatched-roof gazebo adds a tropical touch, while decorative plants enhance the tranquil environment.
Home in Anderson
5 out of 5 average rating, 20 reviews

Lake Front w/Pool @ Tipsy Tiger Lake Hartwell

KimberlyRating, 5 stars1 week ago
Tammy and her house were absolutely amazing! She went above and beyond for anything we needed. The home was fully stocked and had tons of extras. This place inside and out is gorgeous and the pictures just don’t do it justice. The pool and spa were both very relaxing and very well maintained. We definitely plan on coming back whenever we are in the area again. Paddling and kayaking the lake right from the dock was a huge plus. If you ever visit Lake Hartwell - I 100/10 recommend this place!

Weekly house rentals

Superhost
A spacious bedroom features a luxurious king bed with white bedding and decorative throw blanket, set against exposed brick walls. A large mirror reflects the room, which is illuminated by soft lighting from bedside lamps. A plush area rug adds warmth to the wooden floor.
Home in Anderson
4.8 out of 5 average rating, 20 reviews

The Loft 23/ Stay on Main St

ColicusRating, 5 stars1 month ago
Wow—what an incredible find! We honestly couldn’t believe we were lucky enough to stay in this downtown Anderson loft. It was absolutely perfect for my wife and me. The location was unbeatable—right in the heart of downtown, which meant we were just steps away from some fantastic local restaurants. We spent several evenings exploring and enjoying the vibrant food scene, and it truly made our trip special. The loft itself is massive—the open layout gave us so much room to relax, and the design was both stylish and comfortable. One of our favorite features was the pool table, which added a fun, laid-back vibe to our evenings. The hosts were incredibly gracious and accommodating, especially when we asked if a few family members could stop by one evening. We ended up having a lovely dinner together, played a few board games, and made some great memories. Everything about this place exceeded our expectations—from the space to the amenities to the hospitality. This will definitely be our g
Guest favorite
A charming three-bedroom house is set amidst a lush landscape of trees and greenery. A path leads to the front door, flanked by well-maintained shrubs. Natural light bathes the exterior, highlighting the inviting brick façade and the traditional roof design.
Home in Anderson
4.92 out of 5 average rating, 13 reviews

Location! Location! Your home away from home!

TracyRating, 5 stars1 month ago
Alison had great communication and was kind enough to let us check in early. We enjoyed the back patio, very peaceful. Beds were comfortable and kitchen was fully stocked. I recommend Alison’s place if you’re in the area.
Guest favorite
A spacious sunken living area features a large brick fireplace as a central focal point, flanked by two inviting seating arrangements. Natural wood beams extend across the ceiling, and light fills the space through multiple large windows, creating a warm and welcoming environment.
Home in Seneca
4.92 out of 5 average rating, 37 reviews

Lakefront Mid-Century Dream Home / 3 mi to Clemson

SusanRating, 5 stars1 month ago
We had a lovely stay in Lauren's home. You feel like you're living in the Brady Bunch house! Classic 1960s everything. The beds and seating were all very comfortable, and we enjoyed the abundant decks, the hammock, the kayak, the TV... the kitchen had everything you could want, and we appreciated the extra bag of ice and cans of sparkling water they left for us. We highly recommend it. If you're more noise-sensitive, we recommend the downstairs bedroom, which is insulated from the noisier/brighter open layout of the upstairs.
Top guest favorite
A newly renovated cottage is set on a spacious lawn bordered by vibrant greenery. The exterior features a combination of light-colored brick and dark wooden accents. A welcoming path leads to the front entrance, framed by landscaped flowerbeds and trees that provide shade.
Home in Piedmont
5 out of 5 average rating, 25 reviews

Welcome to River House

JulieRating, 5 stars2 days ago
The house was gorgeous and newly renovated. Everything was clean and modern but felt like you were secluded in the country. We loved sitting on the back porch enjoying sunsets. Kitchen was large to feed a big family.
Top guest favorite
A comfortable living room displays a large, light-colored sofa paired with a matching chair. Natural light filters through the large window, creating a bright atmosphere. A casual arrangement of pillows adds subtle texture, while the flooring is a warm wood tone, complementing the room's inviting design.
Home in Anderson
5 out of 5 average rating, 26 reviews

Close to AU & Clemson | No chores on check-out

BraganRating, 5 stars3 days ago
Absolutely perfect!! Can’t thank Jodie enough for being so sweet and responsive. House was pristine and adorable. Thank you!
Top guest favorite
A bright living room is featured, showcasing a gray sofa facing a light rug and a pair of armchairs. A side table rests next to one chair, and a floor lamp stands beside the sofa. Natural light enters through the windows, enhancing the welcoming ambiance.
Home in Seneca
4.99 out of 5 average rating, 87 reviews

Modern & Cozy Cottage-12 min. from Clemson Uni.

KierraRating, 5 stars1 month ago
Heathers place was amazing our family enjoyed our stay very clean and stocked with what you need . Our kids loved the toys and basketball hoop we had a few family games of basketball . Host is very kind and great communication would definitely book again in the future .
Guest favorite
A modern two-story home features a welcoming exterior with light grey siding and a striking red front door. The stone-accented entryway enhances the design. A smooth driveway leads to a two-car garage, surrounded by neatly maintained green grass.
Home in Pendleton
5 out of 5 average rating, 31 reviews

New! 3/2 Home Pendleton, Clemson University!

MonicaRating, 5 stars4 days ago
There are not enough characters available to fully express my gratitude & gush profusely about the host, Robert (and the Air B&B). The ABB is conveniently located to Clemson, Anderson & access to 85. Provided a safe haven, peace of mind (for me), nest for my son while transitioning from campus living to the closing of the t-house while attending/electing to take summer classes. My interactions & communication with Bob eased this mom ‘s mind, answered a million questions, provided guidance, suggestions, has gone above and beyond all expectations of a host. The home/ABB is clean, safe, secure, ample space, free of pests, well maintained and an ideal location. The neighbors are super sweet and friendly. The neighborhood is walkable and I did not have a single apprehension walking my pup at night or on any occasion while I visited, as well. Safe, secure, and peaceful. *Nearest Publix is about 10-min, Zaxby’s/Waffle House, cute Mexican restaurant are walkable, QT is .4 mi/less too* TY!
Top guest favorite
A spacious living area features comfortable seating and a ceiling fan. A flat-screen television is mounted above a sleek fireplace. Natural light filters through multiple windows dressed with light curtains, while a dining area with a table and chairs is visible in the background.
Home in Anderson
4.89 out of 5 average rating, 9 reviews

Hartwell Home, Quality Furniture, Great Location

CarolRating, 5 stars1 month ago
The home was exactly what we needed for a long weekend. Located in a very pleasant and comfortable neighborhood. Everything about the process went smoothly. Owners responded promptly to any questions I had.

Private house rentals

Top guest favorite
A scenic view captures a sunset with vibrant orange and pink hues behind bare trees. Two horses graze peacefully in the grassy field, framed by a gravel drive that leads to the residence. The landscape reflects a tranquil rural setting.
Home in Abbeville
4.99 out of 5 average rating, 69 reviews

The Parlor Two* with peaceful, tranquil views

EmilyRating, 5 stars1 month ago
Beautiful, clean, inviting home! I came with my 8 year old son so he could go to diamond hill mine. Outside of the mine there wasn’t much but farm and country. Very peaceful. Lots of farm animals. It was well worth driving into downtown Greenville for the afternoon which was about an hour away for shopping and lunch! This is the nicest place close to Diamond Hill mine so If you’re coming for the mining, stay at this place. No question!!
Top guest favorite
A charming single-story house is situated on an expansive lawn surrounded by trees. Colorful foliage is featured prominently, signaling the change of seasons. The white exterior is complemented by dark shutters, with a concrete path leading to the entrance.
Home in Pendleton
4.99 out of 5 average rating, 67 reviews

Raven's Ridge

CarolRating, 5 stars2 weeks ago
One of the best airbnb's I've ever stayed in, and one of the best (the best?) hosts. My sister and I were in the area due to a death in the family, and from start to finish Esther thought about our needs, even anticipating stuff we did not! The home is sprawling with everything neat and labeled. We loved the raven and historic images all over the home. Happy to see deer out the window and I think a cow but I was out at the time! I hope my review pays forward all that Esther and her home did for us.
Superhost
A newly constructed single-story home features a welcoming front porch with two black chairs and stone columns, set against a backdrop of green siding and a shingled roof. A concrete pathway leads to the front door, surrounded by a well-maintained lawn and trees.
Home in Anderson
5 out of 5 average rating, 9 reviews

Beautiful, comfortable and cozy house

GreggRating, 5 stars1 month ago
We stayed for our son’s fishing championship on lake Hartwell. Home was close to the launch ramp and easy to get to. Home was clean, well kept, and taken care of. We would recommend to anyone looking to stay close to the lake.
Top guest favorite
A bright bedroom featuring a spacious bed with a light quilt and decorative pillows. A ceiling fan circulates air, while large sliding glass doors provide access to a wooded balcony with seating. Natural light filters through sheer curtains, creating a calming atmosphere.
Home in Anderson
5 out of 5 average rating, 16 reviews

Family friendly waterfront lakehouse near Clemson

DavidRating, 5 stars6 days ago
Great lake house with everything you need for a great experience. Kayaks, paddle boards, life jackets. The lake was right at the bottom of the property. The house was stocked with all the amenities for a fun, hassle-free stay. Checkout was very easy. the stay was fantastic! We would definitely stay here again!
Guest favorite
A swinging wicker chair is positioned on a wooden dock, overlooking a calm lake. Soft clouds drift across a bright blue sky, and lush green trees line the water’s edge, contributing to a serene outdoor setting.
Home in Seneca
4.89 out of 5 average rating, 19 reviews

Cozy Clemson Lake Hartwell Getaway with Dock

TimothyRating, 5 stars1 month ago
Wonderful place with amazing hosts and great views! Everything said in the listing is understated! Our expectations were greatly exceeded. Surprisingly clean and pest free for a lake house, this property has true unobstructed views of the lake and a great outdoor and dock area. This place has everything you need to enjoy a nice, relaxing stay in the country at lakeside. It reminds me of everything we love about Upstate SC!
Top guest favorite
Home in Pelzer
4.94 out of 5 average rating, 32 reviews

The Boyce Home, a small town oasis!

Cristian IRating, 5 stars1 month ago
My family had a wonderful stay at Rhonda’s AirBnB! Her house isn’t just a house but a home. We felt completely welcome as soon as we arrived, and my kids were excited to see the snacks Rhonda had placed out for us. The decor was warm & welcoming, and my wife and daughters especially enjoyed the deep tub that was set up for their “spa days” complete with a beautiful copy of the Bible. The garage had play space and toys for the kids, the backyard was spacious with a lovely couple and their little pup to visit, and the kitchen was perfectly stocked to prepare family meals - right down to a roasting pan! Rhonda promptly answered our questions and was very helpful. I definitely recommend Rhonda’s place if you ever need to stay in the area, especially if you have kids.
Guest favorite
A single-story, red-brick home features a well-maintained lawn and landscaped bushes. The front porch offers a few steps leading to the main entrance. Large windows provide ample natural light to the interior, while a chimney adds a classic touch to the roofline.
Home in Anderson
4.91 out of 5 average rating, 58 reviews

Convenient and Comfort

KentRating, 5 stars8 months ago
I enjoyed my stay! The place was super clean and had everything we needed.
Top guest favorite
A welcoming entryway features a highland cow portrait mounted on the wall, complemented by a small seating area with two pillows on a sleek bench. Natural light shines from the hallway leading to a spacious kitchen visible in the background.
Home in Pendleton
4.98 out of 5 average rating, 48 reviews

Historic Pendleton SC

JamieRating, 5 stars1 month ago
We felt super comfortable, and we were in a great location - close to grocery stores and the Clemson stadium.

Destinations to explore