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House vacation rentals in Anderson County

Find and book unique houses on Airbnb

Top-rated house rentals in Anderson County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Hartwell
4.85 out of 5 average rating, 561 reviews

3 little Care Bear bungalow

Come and experience a little getaway on Lake Hartwell. This is a cute little house, perfect for families or just getting away from the hustle and bustle of Atlanta or Charlotte. There is fishing and you can go swimming in the cove. there's is plenty of parking available on my driveway for your boat SUV or other vehicles. Walmart and Ingles is about 8.2 miles from the house. drive into the city of Hartwell and experience some of the local dining. I left some brochures of my favorite restaurants.

Top guest favorite
The image showcases a serene lakefront view featuring a newly renovated cottage framed by lush greenery. A wooden dock extends into the calm water, providing a peaceful area to relax. The cottage's warm exterior is complemented by the surrounding trees, enhancing the natural setting.
Home in Seneca
5 out of 5 average rating, 124 reviews

Modern Lake Vibes – Kayaks, Dock & Fireplace

The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Top guest favorite
A studio apartment is seen from a corner, featuring a kitchen with orange cabinetry and stainless steel appliances. Two armchairs and a small dining table are positioned in the living area, with a television mounted on the wall. Ample lighting and a neutral color palette are present.
Home in Pendleton
4.88 out of 5 average rating, 130 reviews

Basement apartment in Pendleton w/ sep. entrance

This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Superhost
A wooden dock extends across the calm water, leading toward a lush green shoreline. The surface of the lake reflects the blue sky, while gentle ripples are visible. Surrounding trees contribute to a serene natural setting.
Home in Seneca
4.84 out of 5 average rating, 255 reviews

Cozy Lake House 5 miles from Clemson w Dock

Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

Guest favorite
The exterior of the home is illuminated by string lights, creating a warm ambiance. A set of red adirondack chairs is positioned in the foreground, facing the entrance steps. Soft garden lighting highlights the landscaping, enhancing the inviting atmosphere of the outdoor space.
Home in Townville
4.98 out of 5 average rating, 150 reviews

Hartley’s Haven

Enjoy your stay in this cozy 1 bedroom and 1 bathroom home on Lake Hartwell. We are located 20 minutes from Clemson, 15 minutes to Anderson, and 40 minutes to Greenville, so there is plenty in the area to keep you busy. Located on a dead end street, the neighborhood is very quiet. Our home also has fast wifi and 2 smart TV’s to access any streaming service. We also provide cable. With plenty of parking space in the driveway for vehicles and a boat we can provide a peaceful getaway.

Guest favorite
Home in Anderson
4.97 out of 5 average rating, 29 reviews

Comfortable Cottage

The primary bedroom offers restful sleep with a brand new queen i8 Sleep Number bed & the second bedroom is equipped with a plush pillow-top queen mattress. Step outside to your lighted private back deck perfect for your morning coffee or evening unwinding. This ideal location puts you less than 2 miles from Clemson Boulevard and just 1 mile from the Anderson Civic Center. You’re also minutes from downtown Anderson, Anderson University, Lake Hartwell, and Clemson

Top guest favorite
A charming single-story home is displayed, featuring a welcoming front porch with two rocking chairs. Lush green grass surrounds the property, and a welcoming path leads to the entrance. The well-maintained yard includes shrubs and trees, providing a serene atmosphere.
Home in Anderson
5 out of 5 average rating, 23 reviews

North House - Charming home, walk to AU & AnMed

Welcome to The North House, a beautifully renovated 1923 home offering 2 bedrooms and 2 baths in the heart of Anderson, SC. Blending historic charm with modern amenities, this warm and inviting retreat is just an 8-minute walk from Anderson University and AnMed Health Hospital. Whether you’re visiting campus, working at the hospital, or enjoying a leisurely getaway, The North House provides the perfect combination of comfort, convenience, and Southern charm.

Top guest favorite
A wooden deck is highlighted by a fire pit at its center, surrounded by comfortable seating. Warm lighting adorns the overhead beams, casting a gentle glow over the space. The tranquil lake is visible in the background, with trees framing the scene against a dusky sky.
Home in Anderson
4.97 out of 5 average rating, 155 reviews

Sunset Point-Best view on Broadway - HOT TUB!

This gorgeous property is situated on the picturesque Broadway Lake in Anderson, SC, offering 300 acres of pristine water ideal for pontoon rides, fishing, and making unforgettable memories. This tiered lot boasts an impressive 100 feet of water frontage and a private dock, complete with four kayaks (3 single and one tandem), two paddle boards, and various floats and water fun for guests to explore the lake at their leisure.

Top guest favorite
A bright living space features wood-paneled walls and multiple large windows allowing natural light to illuminate the area. A long wooden bench runs along one wall, complemented by a rustic dining table and chairs, creating a cozy atmosphere.
Home in Anderson
4.96 out of 5 average rating, 188 reviews

Lake Hartwell House - Cozy and Close to Clemson!

Quiet house on Lake Hartwell. Fully equipped kitchen and beautiful finishes. Great place to stay for Clemson football, time with family or personal retreat. Courtesy use of the dock for swimming or boat. Close to Green Pond Landing and Portman Marina. Great restaurants nearby as well as shopping and outdoor activities. 15 min from Clemson University, 20 min to downtown Anderson, just 10 min from 1-85.

Top guest favorite
A newly renovated cottage is set on a spacious lawn bordered by vibrant greenery. The exterior features a combination of light-colored brick and dark wooden accents. A welcoming path leads to the front entrance, framed by landscaped flowerbeds and trees that provide shade.
Home in Piedmont
5 out of 5 average rating, 48 reviews

Welcome to River House

Bring your fishing pole or kayak and enjoy this newly renovated cottage on a peaceful 3.5 acres nestled along the banks of the Saluda River. Centrally located 20 min from Greenville, 35 min from Clemson University and 25 min from Anderson, this beautifully appointed house has all the comforts of home. Enjoy your morning coffee on the large screened back porch while watching the abundant wildlife.

Top guest favorite
The exterior of a spacious single-story home features a red metal roof and light-colored siding. A welcoming blue front door is positioned under a small porch, surrounded by green shrubs. A gravel driveway leads up to the house, framed by trees and a clear blue sky.
Home in Central
4.97 out of 5 average rating, 150 reviews

The House on Oak Grove

Enjoy your time spent in this spacious and peaceful pet friendly space. Nicely appointed with everything you need for a short or long term stay. Ten easy miles to Clemson and 3 miles to SWU. Besides the open living space the house has a screened porch and accomodates 4 with 2 bedroom & 2 adjoining baths. The home includes washer & dryer, coffee bar, granite countertops, and microwave.

Top guest favorite
A cozy cottage overlooks a wooded area, elevated on stilts with a wooden walkway leading to the entrance. The exterior features a dark blue facade, complemented by white windows. Trees surround the property, indicating a tranquil natural environment.
Home in Anderson
4.99 out of 5 average rating, 219 reviews

Lake Escape

This is the perfect lake house for your next family vacation, Clemson football game, or just a long weekend at the lake! Enjoy full access to Lake Hartwell with a private dock and swimming area. The house is located just 20 minutes from both Clemson and Anderson and also just 5 minutes from Portman Marina. Come enjoy some nature, relaxation, and fun at the Lake Escape!

Popular amenities for Anderson County house rentals