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Vacation rentals in Anderson County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Anderson County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Cabin in Greenville
5 out of 5 average rating, 62 reviews

Riverfront A-frame cabin minutes from downtown

🌿 The Cabin at Fern Gully – Nestled on 36 acres of Camp Moondog's private wildlife sanctuary along the Saluda River. This 650 sq. ft. retreat offers two queen beds, a full bath, and modern comforts in a serene, natural setting just minutes from downtown Greenville, SC. 🌿Loft with Queen Bed 🌿Full Bath with Shower, Toilet, and Washer/Dryer combo 🌿Kitchen with Refrigerator, Sink, and Hot Plate 🌿Wrap around porch for beautiful Forest and River views 🌿Own private river spot with fire pit

Top guest favorite
A classic brick two-story house is showcased, featuring a covered front porch with decorative columns. Green landscaping surrounds the home, complemented by well-maintained grass and trees. A pathway leads to the house, inviting guests to explore the entrance further.
Guest suite in Anderson
4.99 out of 5 average rating, 173 reviews

Backyard Hideaway - Anderson, SC

Enjoy a stylish comfy experience at this lovely private suite w/king bed. Located in the Linley Park Historic District of Anderson, SC. One block from acres of green space, walking paths, playground, and shopping. Enter the gated courtyard with an inviting covered porch and lush outdoor space. Less than one mile to downtown restaurants, breweries, and shopping. One mile to Anderson University, AnMed Health. 15 miles to Clemson University. Includes private suite and access to back porch/yard.

Top guest favorite
The treehouse rests elevated among dense trees, featuring a wooden deck with railing and steps leading to the ground. A circular stone fire pit is located at the base, surrounded by gravel, providing an inviting outdoor gathering space.
Treehouse in Seneca
5 out of 5 average rating, 70 reviews

Treehouse at Keowee Hollow

Welcome to the treehouse at Keowee Hollow!!! A CHARMING space nestled in a hollow - with a view of Lake Keowee - perfect for a ROMANTIC getaway or a peaceful retreat. This COZY, brand new, 1 bedroom, 1 bath treehouse offers rest and relaxation. Perfect location. We are minutes from Seneca, 10 miles from Clemson, under an hour to downtown Greenville, Highlands or Cashiers. The outdoor seating area is a perfect place to unwind at the end of a busy day, also features a fire pit & outdoor grill.

Top guest favorite
A studio apartment is seen from a corner, featuring a kitchen with orange cabinetry and stainless steel appliances. Two armchairs and a small dining table are positioned in the living area, with a television mounted on the wall. Ample lighting and a neutral color palette are present.
Home in Pendleton
4.88 out of 5 average rating, 130 reviews

Basement apartment in Pendleton w/ sep. entrance

This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Superhost
A newly renovated home is presented with a wide front porch featuring two black chairs. Lush green foliage and colorful flowers adorn the landscape, enhancing the entrance. A pathway of stones leads to the front door, framed by blue shutters on the windows.
Bungalow in Anderson
4.83 out of 5 average rating, 269 reviews

Bungalow-backyard oasis by Clemson & Lake Hartwell

Come stay at this newly renovated home 20 min. away from Clemson, 2 miles away from Downtown Anderson and Lake Hartwell is minutes away. The wide front porch allows plenty of room for lounging with a cup of coffee in the morning. This home has so much charm with its original refinished hardwood floors, gas log fireplace, and a fully equipped kitchen. Enjoy walking out to the large covered patio with a tv and fire pit perfect for entertaining or unwinding after a long day of activities.

Top guest favorite
A modern cottage features a spacious covered porch with string lights, surrounded by a lush green lawn. Large glass doors invite natural light into the interior, while tall trees provide shade in the background against a colorful sunset sky.
Cottage in Anderson
4.97 out of 5 average rating, 253 reviews

Lakefront dock *hot tub* Anderson/Clemson king bed

Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.

Top guest favorite
A charming single-story home is displayed, featuring a welcoming front porch with two rocking chairs. Lush green grass surrounds the property, and a welcoming path leads to the entrance. The well-maintained yard includes shrubs and trees, providing a serene atmosphere.
Home in Anderson
5 out of 5 average rating, 26 reviews

North House - Charming home, walk to AU & AnMed

Welcome to The North House, a beautifully renovated 1923 home offering 2 bedrooms and 2 baths in the heart of Anderson, SC. Blending historic charm with modern amenities, this warm and inviting retreat is just an 8-minute walk from Anderson University and AnMed Health Hospital. Whether you’re visiting campus, working at the hospital, or enjoying a leisurely getaway, The North House provides the perfect combination of comfort, convenience, and Southern charm.

Top guest favorite
Home in Anderson
5 out of 5 average rating, 31 reviews

Windjammer Lake House

Escape to Windjammer Lake House, a stunning lakefront retreat in Anderson, South Carolina! This charming house offers a perfect blend of comfort and tranquility. Enjoy breathtaking water views, a private dock, and access to kayaks for endless fun on the lake. With a well-equipped kitchen, comfortable living spaces, and outdoor seating, it's ideal for families and groups. We have 20+ ft of water off the dock!!!

Top guest favorite
A vintage caboose, named Chessie Rails, is situated in a grassy area surrounded by trees. String lights create a warm ambiance above a landscaped outdoor space featuring a fire pit and seating area. The backdrop is complemented by a colorful sky at dusk, enhancing the serene atmosphere.
Train in Due West
4.99 out of 5 average rating, 156 reviews

Chessie Rails - Caboose w/HotTuB

Stay in a private caboose!!! Book your stay at Chessie Rails and experience a renovated caboose. But this is no ordinary train car. In October 2022 we started the process of bringing this vintage 1969 caboose back to life. Set back in your own private field with rolling hills as well as cows grazing on green grass. The outdoor space showcases a Hot Tub, Waterfall, Wood Fire Pit, Outdoor Shower, and more!

Top guest favorite
The exterior of a spacious single-story home features a red metal roof and light-colored siding. A welcoming blue front door is positioned under a small porch, surrounded by green shrubs. A gravel driveway leads up to the house, framed by trees and a clear blue sky.
Home in Central
4.97 out of 5 average rating, 156 reviews

The House on Oak Grove

Enjoy your time spent in this spacious and peaceful pet friendly space. Nicely appointed with everything you need for a short or long term stay. Ten easy miles to Clemson and 3 miles to SWU. Besides the open living space the house has a screened porch and accomodates 4 with 2 bedroom & 2 adjoining baths. The home includes washer & dryer, coffee bar, granite countertops, and microwave.

Top guest favorite
The exterior of the apartment building is visible, featuring a rustic design with wooden elements and a metal roof. A spacious driveway leads to the double garage doors, surrounded by landscaped greenery and blooming flowers. Trees in the background provide a peaceful environment.
Guesthouse in Hartwell
4.99 out of 5 average rating, 172 reviews

1 bedroom lake front apartment with gorgeous views

Relax in a cozy apartment on Lake Hartwell. The apartment is located in a secluded peaceful, cove near downtown Hartwell and is in close proximity to hiking and numerous outdoor activities in the hill country of Georgia and South Carolina. The apartment sleeps 2 comfortably and is fully equipped with a kitchen and a private laundry facility.

Top guest favorite
A charming cottage is nestled among trees, showcasing a blue exterior and a welcoming front porch. Two rocking chairs are positioned on the porch, and a few flower beds add color to the landscape. Gravel paths lead to the entrance, providing a serene country feel.
Tiny home in Seneca
5 out of 5 average rating, 119 reviews

Bell Cottage

Come stay awhile at this adorable little cottage! It is a brand new construction nestled just inside the woods on the edge of our property. It is 432 sq feet and has all the amenities you need to enjoy your stay. It has a full kitchen, living room, bedroom with a queen bed, bathroom and laundry.

Popular amenities for Anderson County vacation rentals