
House vacation rentals in Southeast Jacksonville
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Top-rated house rentals in Southeast Jacksonville
Guests agree: these houses are highly rated for location, cleanliness, and more.

Enlivening house with spacious parking and patio
♬ Located right behind Memorial Hospital !!! Your family will be close to everything when you stay at this centrally-located place. Location with easy access to Beach Boulevard and Atlantic Boulevard. 15-20 minutes away from Jax Beach, St Johns Town Center, Downtown and Five Points. The location is right in the middle between Jacksonville Downtown and Jacksonville Beach. Big driveway that could fit 6 cars or more. Comfortable and covered patio. Vinyl disc record player and BBQ at your pleasure.

2BR/1BA Home. Minutes away from Mayo & Beaches
Savor your stay in a recently remodeled, quiet neighborhood house that is perfect for families. This unique two-bedroom, one-bathroom house has all you need for a restful and enjoyable visit. Aside from the two bedrooms, 1 couch in the living room become full-size bed. The bedrooms and living room have Smart TVs. We provide lots of on-site parking as well as WiFi connectivity. The back of the home has access to the shed and the entire yard. Minutes from Mayo Clinic, beaches, and shopping malls.

Serene Cottage in Walkable, Historic San Marco
This beautifully renovated cottage is a 5-min walk to local Hospitals and Clinics. San Marco Square is within walking distance w/ a theater, shops, & the best restaurants in town. The Southbank Riverwalk is blocks away & lovely for a sunset stroll. The elevated people mover is close by & handy for concert and stadium events. This home is perfect for professionals & health care visitors. Wonderful neighborhoods of Avondale & Riverside are just across the river. Centrally located for easy access.

Beach Escape Near Mayo | Fenced Yard + Fast WiFi
🌴 Work-Ready Ground-Floor Oasis at Jacksonville Beach 💛 Why You’ll Love Staying Here ✨ Designed for Productivity & Relaxation – Two workstations with fast Wi‑Fi, plus a serene backyard pergola for true work-life balance 🌊 Steps to the Beach & Local Hotspots – Just blocks from the ocean, top dining, breweries, shops, and the Jacksonville Beach pier 🐾 Family & Pet-Approved – Fully fenced yard, washer/dryer, beach gear, and a layout perfect for couples, friends, or traveling professionals

Special lakefront retreat
Your family will be close to everything when you stay at this centrally-located place. Minutes to major shopping and restaurants and just 15 minutes to Jacksonville beach. Only 10 min to TIAA Bank Field to see the Jaguars or enjoy your favorite events. Home features a scenic backyard with lake views. You can sit on the fishing deck or relax on the dining family deck . If you like to kayak, go for it. Then come back to enjoy a nice evening with family or friends around the firepit.

Unwind. Cozy Creekside Cottage near Ortega/NAS
Enjoy this charming creekfront cottage in the heart of Jacksonville. Unwind as the sun sets over the water, relax under shady cypress trees while wildlife travel about the tidal creek, enjoy cocktails on the dock, engage in boating or try your luck fishing. A boat ramp is nearby for boat launching. (Plenty of room to park Boat/Trailer on the nearly 1 acre lot ) While this unique retreat provides a tranquil getaway, it is also centrally located making it convenient for you to get around.

Private FL Home with Pool, Hot tub & Luxury Master
This is a lovely family home in the Mandarin area of Jacksonville which has undergone many renovations and upgrades. The master boasts its own, ensuite, tv, fireplace and sitting area, as well as a private entrance from the pool and hot tub area. The house itself has newer furnishings, flooring, modern decor, a large fenced in backyard, pickle ball court and firepit. Located in a safe South East Suburb of Jacksonville, not far from shopping, beaches and many other Florida attractions.

Beautiful Coastal Home near Mayo. Pet Friendly!
Come and relax at this impeccably clean and cozy coastal home less than 3 minutes from the Mayo Clinic Jacksonville, 7 minutes from Ponte Vedra Beach/TPC Sawgrass, and 20 minutes from EverBank Stadium. With a fully-equipped kitchen, washer/dryer, smart televisions with every streaming service, and a various assortment of books and board games, you are sure to have everything you need to make your stay as stress-free as possible. Ideal for the entire family, including your furry friends!

Cozy Riverside Home. Walking Distance To 5-Points!
This home is located in the heart of Riverside. Cozy and aesthetic! You are centrally located in the center of 5-points. Park your car and leave it!! You are within walking distance to everything. We also have fun bikes located on the property. This home is perfect for couples, business travelers, or if you are traveling alone. - Due to Coronavirus, we’re taking extra care to disinfect frequently touched surfaces between all reservations. • Parking is available on the STREET ONLY

The confetti house - 1 mile from the Mayo clinic!
Cozy home located in a quite and safe neighborhood. 3 1/2 miles from the beach, 1 mile to the Mayo clinic, 5 miles to the Town Center, 1 1/2 miles to a marina and 1 mile to a state preserve with access to the intracoastal water ways. Walking distance to a park with tennis courts and playground for children. Adventure Landing waterpark is 2.5 miles away. 1 mile walking distance to stores and restaurants. Enjoy a cup of coffee in the screened in lanai listening to the Koi pond waterfall!

Fancy Dancy
Experience the charm at "Fancy Dancy". Nestled within Avondale’s historic community, this home is strategically located within walking distance to a plethora of restaurants, parks, boutiques, and the serene St. Johns River. For the Sports fans, Jacksonville Jaguars stadium is only a 10 min drive. Whether you're seeking culinary delights, outdoor adventures, or sporting events, everything you desire is just steps away. Discover the perfect blend of comfort, style, and convenience.

Cozy Retreat By Mayo, Beach, Pet Friendly Backyard
Send me a message for the NEW YEARS discount Local private host delivering exceptional 5 star experiences nestled in this quiet neighborhood Luxurious beds and blackout curtains offer a relaxing oasis to enjoy your stay. Gather around our large table with family and friends to make memories Pet & family friendly! Sleep 7 guests Convenient to Cruise Terminal, Beach, Mayo, and Shopping/ Dining Private fenced in backyard In Unit Washer/ Dryer DBPR DWE2613890 TDT #1871 LBT #412575
Popular amenities for Southeast Jacksonville house rentals
House rentals with a pool

*Heated Pool, Hot Tub & Grill Retreat • Free Wi-Fi

Historic Hollywood House w/Pool

Fancy Private Pool Home in Jax beach!

Private Pool Home • Quiet • Near Beaches & Dining

The House. Private Pool. Pet Friendly.Quiet area.

Pool Home with Game Room in Heart of Jax Beach!

Retreat on the river

Quiet and Serene House with Heated pool near beach
Weekly house rentals

3 BR House Near Beaches and Shopping

Cozy Home

Zen Flamingo: Poolside Peace Near Beaches and TPC

Rossi Cozy Cottage - Convenient Location

New Screened Heated Pool with Spacious Living Area

Sunshine Bungalow

HOME | Cozy, quiet, walkable, central, San Marco.

Cozy Escape | 2BR | 1BA | Fenced | Beach/Mayo/UNF
Private house rentals

Heart of San Marco • Porch • BBQ • Bikes

Cozy Fairfax/Avondale Bungalow

Happy Coastal Cottage | 3BR with Outdoor Oasis

Jax Beach Home with Heated Pool!

Stylish Brick Bungalow Retreat

Jacksonville 2-BR Bungalow | Sauna & Dog-Friendly

The Beach Lodge

The Retreat, walk to Mayo Clinic!
When is the best time to visit Southeast Jacksonville?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$26,925 GYD | G$26,716 GYD | G$29,012 GYD | G$27,343 GYD | G$28,595 GYD | G$27,760 GYD | G$28,386 GYD | G$27,134 GYD | G$25,464 GYD | G$28,386 GYD | G$30,265 GYD | G$30,473 GYD |
| Avg. temp | 13°C | 15°C | 17°C | 20°C | 24°C | 27°C | 28°C | 28°C | 26°C | 22°C | 17°C | 14°C |
Quick stats about house rentals in Southeast Jacksonville

Total vacation rentals
Explore 660 vacation rentals in Southeast Jacksonville

Nightly prices starting at
Southeast Jacksonville vacation rentals start at G$4,174 GYD per night before taxes and fees

Verified guest reviews
Over 24,790 verified reviews to help you choose

Family-friendly vacation rentals
460 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 330 rentals that welcome pets

Vacation rentals with a pool
150 properties feature pools

Rentals with dedicated workspaces
420 properties have a dedicated workspace

Wi-Fi availability
650 of Southeast Jacksonville vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Southeast Jacksonville rentals

4.8 Average rating
Southeast Jacksonville stays are highly rated by guests—averaging 4.8 out of 5!
Destinations to explore
- Townhouse rentals Southside
- Rentals with beach access Southside
- Rentals with a patio Southside
- Rentals with pools Southside
- Rentals with lake access Southside
- Rentals with a home theater Southside
- Rentals with an EV charger Southside
- Rentals with outdoor seating Southside
- Guesthouse rentals Southside
- Condo rentals Southside
- Private suite rentals Southside
- Rentals with breakfast Southside
- Rentals with a hot tub Southside
- Apartment rentals Southside
- Rentals with a washer and dryer Southside
- Hotel rooms Southside
- Fitness-friendly rentals Southside
- Family-friendly rentals Southside
- Waterfront rentals Southside
- Rentals with a fire pit Southside
- Pet-friendly rentals Southside
- Rentals with a fireplace Southside
- Smoking-friendly rentals Southside
- House rentals Jacksonville
- House rentals Duval County
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- EverBank Stadium
- Summer Haven st. Augustine FL
- Lightner Museum
- Kathryn Abbey Hanna Park
- Fountain of Youth Archaeological Park
- St Augustine Amphitheatre
- Adventure Landing Jacksonville Beach
- VyStar Veterans Memorial Arena
- Ravine Gardens State Park
- Saint Augustine Town Plan Historic District
- St Johns Town Center
- St. Augustine Alligator Farm Zoological Park
- TPC Sawgrass
- University of North Florida
- Memorial Park
- Fort Clinch State Park
- Little Talbot
- Vilano Beach Fishing Pier
- Anastasia State Park
- Marineland Dolphin Adventure
- Autobahn Indoor Speedway & Events - Jacksonville, FL
- San Sebastian Winery
- Museum of Science and History
- Friendship Fountain




