Vacation rentals in Southeast Jacksonville

Luxurious Craftsman in Historic San Marco

Never Drive Again! Immaculately renovated San Marco Bungalow, just a minute from excellent restaurants, retail, entertainment, hospitals & easy transit (via San Marco's FREE Beachside Buggy App) to everything else. Features include an inviting front porch, interior foyer, charming living room w/gas fireplace, new kitchen w/SS and granite, indoor laundry, historic architectural features, and private backyard w/ sitting area, fire pit, games & BBQ! Incredible location with unmatched walkability!

Restful Studio Intercoastal West

Unwind in style within this peaceful retreat. A private entrance opens up to a fully furnished suite near Golf (Windsor Parke Golf and Country Club - 1 mile), Jacksonville Beach (6 miles), and Mayo Clinic (3 miles). The kitchenette features a microwave, refrigerator, stove, and dishwasher. A variety of dining options, including fast food, sandwich shops and upscale restaurants, as well as a supermarket and pharmacy, are situated within 1 to 2 miles. St. Johns Town Center is only 15 mts away.

Studio Suite in Beautiful Central Neighborhood

Studio guest suite with queen bed and kitchenette in beautiful Miramar neighborhood, just 5 minutes from historic San Marco. Close to restaurants, grocery, MD Anderson Cancer Center and Wolfson Children's Hospital. Owners live in main house on site but suite has its own private entrance and parking. You will have access to an outdoor dining space and fenced in backyard. Dogs live on premises but will not interfere, although you may hear barking. Sofa bed available if needed, please inquire.

XL family home, Pool, Pool table, Private 1 acre.

This well designed large home offers the perfect balance of luxury, comfort, and fun. Great for relaxing and reconnecting in style. Enjoy sun-filled living spaces : A family room with pool table, games, formal dining room, a fully stocked kitchen, coffee nook, pergola with an outdoor grill kitchen setup and an inviting inground pool which is shared with the cottage in the back on the same property. Conveniently located , this home offers space and amenities to make your stay truly memorable.

Lake View Escape to The Exchange

Give us your worries and we will give you an escape. Welcome to the Exchange! This Orange Park unit supports your work requirements and your playful desires. Multiple high volume healthcare facilities surround the area and the Naval Air Station is in the backyard. Luxury dinning and outdoor water activities abound. This new unit offers access to a resort style salt water pool, private garages, state of the art fitness center and wellness studio, dog park, clubhouse and lounge, and much more.

Quiet Retreat 1 bedroom 1 bath

Kick back and relax in this calm, stylish space centrally located apartment with all inclusive, resort-like amenities in Jacksonville, Florida. We are just off of the main highway just minutes from the Mayo Clinic, UNF, and the St. Johns Town Center. * Covered garage parking and elevator access makes it easy to come and go! Take a dip in the beautifully welcoming pool, work out in the fully equipped, 2-story gym, or you can handle your business in the office spaces. There's so much more!

La Casita Chiquita Near Events & Entertainment!

Welcome to "La Casita Chiquita" our unique little guest cottage - in the heart of Jacksonville! This 250 square foot cottage, with a loft bed and comfortable amenities is nestled in a garden setting, underneath majestic trees. You can be away from it all - and just blocks to sports, entertainment & convention venues, craft breweries, sports bars, unique eateries, and museums. Are you here for business? Downtown is 5 minutes away and major medical facilities less than 10 minutes away.

Sunset Retreat | 1BR | 1.5BA | Pool | Gym | Garage

Entire modern, luxurious, and spacious apartment. Stunning lake-front view with gorgeous sunsets. Large king bed and queen sleeper sofa provide a comfortable stay for 4. Whether your stay includes a day of shopping, a trip to golf, going to work, or to unwind at the beautiful Jacksonville beaches, you are never far from your destination. Less than 5 miles to the St. Johns Town Center, 7 miles to the nearest hospital, 11 miles to the beaches, and 6 miles to the nearest golf course.

Mandarin 3BR + Flex + 3 Bath

Welcome to your fully furnished 3-bedroom, 3-bath home with a flex room in the heart of Mandarin, close to everything. Renovated in 2025, this home features modern fixtures, plush furnishings, and thoughtful amenities. Enjoy two queen bedrooms, a third bedroom with two twin beds, a full kitchen, and a cozy living area. Includes Wi-Fi, washer and dryer, and all utilities. Safe, clean, and quiet for your enjoyment in a peaceful Florida neighborhood.

Blue Bird Paradise

Welcome to “Bluebird Paradise”. Come visit our bright, beautiful, 400 sq. ft “Guest House”, detached from our home with a porch overlooking our beautiful Florida backyard with pool. The commute is very good; it is located less than 30 minutes from the city, 30 minutes from the beach and 30 minutes from the famous historical St Augustine. Peace and quiet await you. A guesthouse is a detached building that shares the property with the host.

Lux King Bed Southside Pool Gym Near Mayo Beach

Stay in the best location! This stylish 1-bedroom is in a quiet luxury community with pool and gym. Everything—Mayo Clinic, Town Center, the beach, and Downtown—is 15 minutes or less away. Inside, enjoy a complete kitchen, inviting living space, and cozy bedroom. With a calm setting and professional vibe, this apartment is ideal for business, treatment, or a relaxing Jacksonville getaway.

King Suite Vallarta

Minutes to It All: Beach, Downtown & Your Spacious Haven!* • * WiFi. **Rooms feature:** - King and Queen beds - TVs & dedicated workspace -living room couch and dining island **Full amenities:** - Kitchen (stove, microwave, fridge, coffee maker, sink, tools, toaster) - Washer/dryer - Outdoor bench Ideal for work, families, or extended stays - everything for a seamless visit!