Hotel vacation rentals in Southern Oregon

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Top-rated hotel rentals in Southern Oregon

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Top guest favorite

A spacious guest room features exposed brick walls and a large window with blue curtains. A plush king bed with decorative pillows is complemented by bedside tables and stylish lamps. A seating area with a wooden chair adds comfort and warmth to the space.

Hotel room in Jacksonville

5 out of 5 average rating, 38 reviews

Jacksonville Inn RM #1 | King Suite w/ Lux Tub

Built in 1861, The Jacksonville Inn is an iconic historic landmark located in the heart of downtown. This 8-room boutique hotel has been recently renovated with a fresh look while honoring its rich past. Once named the "most romantic" hotel in Oregon, The Jacksonville Inn is a haven for visitors to Applegate Valley Wine Country and the prestigious Britt Festival. This king bed suite offers a luxurious copper soaking tub, walk-in shower, smart TV, and Nespresso coffee. Walk to Britt Festival.

Guest favorite

An open-concept living area features a round glass dining table surrounded by modern green chairs. A cozy couch and a brown armchair are positioned near a flat-screen TV mounted on the wall. The kitchen is equipped with wooden cabinets and a countertop with barstools.

Hotel room in Medford

5 out of 5 average rating, 5 reviews

Peach Street Inn | Suite 2 | Sleeps 4

Welcome to Suite 2 at the Peach Street Inn, your perfect retreat just blocks from downtown Medford. Our largest suite is designed for comfort & style, featuring a plush king bed & full-size pull-out couch to accommodate up to 4 people. This spacious suite boasts an open-concept kitchen, living room, and dining area, making it ideal for both relaxation & entertaining. The kitchen is well equipped with modern amenities, & the living room is a cozy space with comfortable seating & a new SMART TV

Superhost

A cozy studio space features a spacious bed with white linens and a soft pink accent pillow. A sleek gray sofa is positioned nearby, complemented by a round pink coffee table. Light streams through large windows adorned with light gray curtains, against a backdrop of textured wallpaper.

Hotel room in Eugene

4.91 out of 5 average rating, 75 reviews

Chic + Luxe ApartHotel in the pulse of the city

Effortless style and muted pastel accents offer sophistication and simplicity. Completely restored 1910 apartment building. Comfortable loft style space with every detail considered. Perfect kitchen for cooking a full meal. Smart 65" TV in the living/sleeping area ready for streaming. West Elm sofabed with Brooklinen luxury linens and towels. Public Goods bath essentials. Dining table for 2 and also a dedicated desk workspace with hi-speed wi-fi throughout. AC/Heat with a digital thermostat.

Superhost

A spacious bed is positioned against a mural depicting mountains and a large moon. A bedside table with a golden lamp and a small decorative item adds a touch of elegance. The warm wood flooring complements the overall design.

Hotel room in Dunes City

4.96 out of 5 average rating, 24 reviews

Lakeside Studio w/ Fishing, boat ramp, dock, kayak

Book the Marina Room @ The Florentine Waterfront Hotel — a charming studio less than 10 mins from Old Town Florence. You'll enjoy breathtaking sunrises and beautiful starry nights on the Oregon Coast! This newly renovated studio features 1 queen bed, sitting area with couch, a kitchenette, and curated accents w/ custom built furniture for a truly one of a kind experience! This historic property features a private boat launch & dock with some of the best kayaking, birdwatching, & fishing!

Guest favorite

A bright living space features a blue velvet sofa complemented by white upholstered chairs. A stone fireplace, adorned with decorative items, serves as a central focal point. Elegant artwork and a sparkling chandelier enhance the inviting atmosphere of the room.

Hotel room in Gold Beach

4.96 out of 5 average rating, 125 reviews

Coastal King Room at Endicott Gardens 21 & Over

Welcome to Endicott Gardens Bed & Breakfast, Spa and Tea House! We are a smoke free, pet free, 21 and over venue where you can get away from it all and relax! You can also add on our organic, innovative farm to table breakfast to your stay (breakfast is additional). All rooms have private ensuite bathrooms and your own heat and air! This room features a King Bed, with private bath and tub/shower combo! We are located 7 minutes from the ocean and right across the street from the river!

Guest favorite

A spacious bedroom is illuminated by natural light from two windows, featuring subdued green walls and a large king bed adorned with crisp linens. A cozy sitting area is complemented by a textured rug, and a stylish overhead light fixture adds warmth to the space.

Hotel room in Ashland

5 out of 5 average rating, 34 reviews

Grand Luxe Suite with Jetted Tub

Our King Suite featuring large jetted tub to relax and unwind. WE ARE STEPS TO ALL ASHLAND HAS TO OFFER. STAY AND PLAY AT SWANK HOUSE SUITES. 🔹 1 block to grocery store 🔹 2 blocks to Ashland Escape Room 🔹 3 blocks to start exploring all the downtown restaurants 🔹 4 blocks to Growler Guys 🔹 6 blocks to Ashland's Plaza Center 🔹 7 minute walk to Chozu Bath & Tea Gardens 🔹 BIKE & HIKE (ride from your front door to the trails) 🔹 Plush KING bed, coffee, & attention to every detail

Guest favorite

A small room features a queen bed with a white comforter, framed by wooden paneling and wide windows allowing natural light. A small cafe table and a chair sit beside the bed, enhancing the room's functionality.

Hotel room in Yachats

4.74 out of 5 average rating, 568 reviews

Pedal Out - Gray

This is one of 5 hostel-style rooms located within an eclectic complex of boutique lodging at The Drift Inn, Yachats, Oregon. Sorry, no pets. This tiny room offers a step up from "bare essentials." It includes a flat-screen TV, storage for luggage under the bed, and a small fold-down table with chair for seating. The bed dominates the majority of the room, so be aware when booking - this is a very tiny private bedroom. (Shared restrooms, showers, and kitchenette across the hall.)

Guest favorite

A bright and inviting bedroom features a spacious bed with a yellow and white spread, complemented by wooden accents. Two framed art pieces adorn the wall, providing a modern touch. Natural light streams in, enhancing the welcoming atmosphere.

Hotel room in Medford

4.85 out of 5 average rating, 74 reviews

City Center Motel - Queen Room

City Center Motel, your go-to for modern comfort and convenience. Family-owned with a personal touch, our rooms are designed to make your stay easy and relaxing. Enjoy amenities like air conditioning, a refrigerator, microwave, k-cup coffee maker, hair dryer, iron and board, and free Wi-Fi. Whether you’re here for work or leisure, our dedicated team is committed to providing excellent service and ensuring a memorable stay. Experience comfort and care, all in one place.

Guest favorite

A spacious wooden deck is featured, adorned with rustic furnishings and offering views of the busy street below. A sign displaying 'Ski Inn Tap House Hotel' is prominently positioned above, while the surrounding area showcases local shops and trees against a partly cloudy sky.

Hotel room in Sisters

4.93 out of 5 average rating, 146 reviews

Ski Inn Taphouse Hotel, Downtown Sisters- Room 104

Enjoy our brand-new, 6 unit, boutique hotel located in the heart of downtown Sisters, Oregon. This listing is for Room 104 featuring a king bed, seating area, private bathroom, and access to the shared, wrap-around patio with breathtaking views of the Three Sisters mountain peaks. You'll experience a private, unique setting upstairs while having the option to eat and drink as a local downstairs at the Ski Inn Taphouse.

Superhost

A cozy bedroom features a spacious bed with plush linens, accompanied by decorative pillows. A vibrant patterned accent wall adds a modern touch. Two bedside lamps provide soft lighting, and a large window offers natural light. A wooden door with a keyless entry system is visible.

Hotel room in Bandon

4.83 out of 5 average rating, 169 reviews

B. Dune: Feel RELAXED in this king-bed room!

Welcome to the B-Side Motel & RV Park located in gorgeous Bandon on the famous Oregon Coast! Come enjoy year-round fishing, hiking, beach-combing, golf or simply relaxation in one of Oregon’s most beautiful gems. Your private room includes a King bed with plush linens, private bathroom with shower and access to on-site facilities such as free wi-fi, clean bathrooms, shared outdoor spaces, and a coin-op laundry.

Superhost

A bright sleeping area features a light-colored bedspread covering a spacious bed with a tufted headboard. Decorative wall art hangs above the bed. Nightstands with lamps are positioned on either side, and a mirrored wall reflects the room's layout.

Casa particular in Eugene

4.8 out of 5 average rating, 45 reviews

Monet Studio

Enjoy a stylish experience at this centrally-located place. It is located close to downtown and the University 4 minute drive. Restaurants, Bars, and locally grown food market are one block distance. It has a very comfortable Tempurpedic queen bed. Enjoy our Netflix and MAX. Across the street, in Amazon park, there are a walking trail, a dog park, a swimming recreation facility, and YMCA (gym-pool).

Guest favorite

A simple cottage exterior is viewed from the backyard. A wooden deck with two reclining chairs provides a place to relax. French doors open into the cottage, while stone landscaping and a fenced area are visible in the background.

Private room in Applegate

4.88 out of 5 average rating, 188 reviews

Peaceful Cottage in the Applegate Wine Country

This cottage is nestled deep in the idyllic Applegate Valley. It is the doorway to wonderful things that you can do in this valley that include hiking, river rafting, fishing, floating in the lake, a basecamp for the Pine to Palm annual race, seasonal lavender farms, and wildlife, but most people come here to do wine tasting and tours of our world renown wines and vinyards.