Hotels in South San Francisco

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Top-rated hotels in South San Francisco

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Superhost
A cozy bedroom features a spacious bed with decorative pillows and a soft blanket. Two bedside lamps provide gentle lighting beside wooden furniture. A large mirror reflects the room's details, while skylights above allow natural light to brighten the space.
Hotel room in Berkeley
4.94 out of 5 average rating, 147 reviews

Rock Roulade Cocoon

Your own space/ no shared rooms, easy access ground floor and convenient location. This unique place has a fresh style all its own. Formally a secret famous recording studio for pop-rock bands, it was known as “The Hearst”. World famous records by the Killers were made here, “Hot fuss” and “Sawdust”. The first room, (now bedroom) was the control room with recording equipment and the second room (now tub room) was where the musicians played. Welcome pets for a fee if $35/per pet -per night.

Guest favorite
Hotel room in Yerba Buena
5 out of 5 average rating, 12 reviews

Sophisticated Stay | Cable Cars Tours. Gym

Located on Market Street, Hyatt Regency San Francisco Downtown SOMA is a sophisticated destination hotel close to the city’s most innovatively stimulating sights. Attractions are just nearby: ✔Picturesque picnics at Golden Gate Park ✔Contemporary and modern paintings, photographs, sculptures and designs from the 20th century, all housed at SF MOMA ✔Postcard-worthy shots, at Golden Gate Bridge ✔Beaux-Arts wonder, the Palace of Fine Arts ✔Best views of San Francisco at Twin Peaks

Top guest favorite
A cozy bedroom features a queen size bed adorned with a floral-patterned coverlet and decorative pillows. A colorful chandelier hangs above, while built-in shelves showcase books and decor. Natural light filters through sheer curtains, illuminating the warm, earthy tones of the room.
Casa particular in San Francisco
4.97 out of 5 average rating, 89 reviews

Elegant Noe Valley/Glen Park private suite

Elegant private suite in the Noe Valley/Glen Park neighborhood of San Francisco on a quiet, safe street convenient to transport (J Church Streetcar, 24 Muni bus, BART), restaurants and shopping. Private entrance, queen size bed, high fidelity entertainment system, private white marble bathroom w/ shower and soaking tub, private office with desk and printer; refrigerator, microwave and coffee maker. Free parking on quiet street. Ideal for couples who like to walk. Infants permitted.

Guest favorite
A well-appointed sitting area is created with two elegant armchairs and two striped chairs surrounding a glass-topped coffee table. A decorative fireplace serves as a focal point, complemented by soft lighting from the lamps on either side.
Hotel room in Nob Hill
4.94 out of 5 average rating, 17 reviews

San Francisco Suites Studio lll on Nob Hill

Experience true hospitality in an Edwardian setting that is filled with European paintings,antique furniture,crystal chandeliers and a full service kitchen in every suite. You can also have your coffee upstairs in the gazebo overlooking the City. In the afternoon wine,cheese and crackers are served in the lobby and sherry is offered in the evening in front of the fireplace. The concierge will make your dinner reservations and when you depart, the cable car awaits on Powell Street.

Superhost
The exterior view of The Marker showcases its Beaux-Arts architecture with elegant detailing. Multiple stories feature large windows, illuminated at dusk, creating a welcoming ambiance. The building is framed by trees and streetlights, set against a softly lit sky.
Hotel room in Tenderloin
4.87 out of 5 average rating, 119 reviews

Union Square Stay | On Site Restaurant & Bar

Steps from San Francisco’s vibrant Union Square, The Marker blends over a century of hospitality with modern elegance. This boutique Beaux-Arts hotel offers curated amenities like PATH water bottles, FloWater stations, and a 24- hour state-of-the-art fitness center. Dine at Tratto, serving rustic Italian dishes and craft cocktails. With concierge service, curbside valet parking, and California Green Lodging certification, The Marker pairs timeless charm with contemporary comfort.

Superhost
Hotel room in Downtown / Union Square
4.85 out of 5 average rating, 110 reviews

Book-filled Writer’s Alcove in the lobby

Channeling the spirit of the Beat Generation, every room at Hotel Emblem is a creative retreat featuring a writing desk with an inspiration board. Enjoy plush pillowtop beds with Italian linens, a 55" HD TV, and unique touches like a meditation bowl, typewriter, and coloring books. Thoughtful amenities include in-room coffee and tea, ROIL bath products, and high-speed internet. With pet-friendly options and hotel bikes, your San Francisco stay is both inspiring and comfortable.

Superhost
A room with two double beds is framed by wooden headboards, featuring crisp white linens. A nightstand with a lamp and a phone is positioned between the beds, enhancing the functionality of the space.
Hotel room in Millbrae
4.89 out of 5 average rating, 101 reviews

Bay Area Escape | Hotel Room. Free Breakfast

If you plan to explore the Bay Area, The Millwood Inn & Suites is a great jumping-off point. This quaint hotel is located in Millbrae, California, only minutes from Bay Area attractions such as the Golden Gate Bridge. It is also only a six-minute drive from San Francisco International Airport, perfect for those flying in! Be welcomed into a world of comfort and convenience after a long day of exploring California's best. ✔ Free breakfast ✔ Free parking ✔ Fitness center

Superhost
A spacious guest room features a king bed with crisp white linens against a warm wood headboard. A window with light-filtering shades provides natural light, while modern fixtures and a wooden shelving unit offer functionality and style.
Hotel room in Downtown / Union Square
4.82 out of 5 average rating, 49 reviews

Fun Respite | Happy Hour. Game Room. Pet Friendly.

Axiom Hotel, a 4-star establishment in San Francisco's city center, is an ideal accommodation for those looking for a fun hotel to stay in during their trip to SF. It features a fitness center and a game room. Guests can also venture out to see prime attractions nearby, like Moscone Center and the Ferry Building. ✔ Fitness center ✔ Robot-delivered room service ✔ Pet-friendly ✔ Arcade games ✔ Cafe on-site ✔ Breakfast, lunch, dinner, boba and a full bar

Superhost
Hotel room in Pacific Heights
5 out of 5 average rating, 4 reviews

Monroe Studio 325

The Monroe Residence Club is a residential hotel located centrally in the heart of San Francisco with public transportation at our doorstep and local shops and businesses nearby. It is conveniently located just a block from Whole Foods, blocks from a the iconic Lafayette Park, within walking distance of several hospitals and more! The Monroe offers 24-hour front desk security, breakfast and dinner on-site, as well as common areas for congregating.

Guest favorite
An outdoor pool area features a rectangular swimming pool surrounded by lounge chairs positioned on wooden decking. Palm trees provide shade, while several seating areas with tables and chairs are visible in the background, all set against a modern architectural backdrop.
Hotel room in Mountain View
4.9 out of 5 average rating, 879 reviews

King Bed at Shashi Hotel in Mountain View

Experience our King room type at Shashi Hotel Mountain View, an Urban Resort. Conveniently, located in the heart of the Silicon Valley - walking distance to Shoreline Amphitheatre. Taste incredible cocktails and delicious bites at our Emerald Hour Bar designed by our Michelin-rated Chef. Enjoy complimentary amenities including our outdoor pool, fitness center, sauna and steam rooms. New for 2025 - daily wine tasting, yoga, zumba, and live music.

Top guest favorite
A comfortable living area features a light-colored sofa with green accent pillows, accompanied by a modern armchair. A round coffee table sits in the center, complemented by a decorative piece. Natural light enters through two windows, framed by soft curtains, highlighting the warm tones of the walls.
Hotel room in Nob Hill
5 out of 5 average rating, 16 reviews

1 Bedroom Apartment Nob Hill Inn

This 1-bedroom apartment with a living room in the heart of Nob Hill offers the perfect blend of comfort and convenience. What makes this space special is the combination of privacy and space, featuring a separate living area for relaxation and a well-appointed bedroom for restful nights. Located in the prestigious Nob Hill neighborhood, you’ll be steps away from top San Francisco attractions, iconic landmarks, and local dining gems.

Top guest favorite
A spacious living area is highlighted by a light-colored sofa, accompanied by a patterned throw and decorative cushions. Artwork adorns the walls, and a dining area with modern chairs is visible in the background, leading to the kitchenette and staircase.
Casa particular in Panhandle
4.95 out of 5 average rating, 130 reviews

Boutique large studio in NoPa San Francisco

Self-contained large studio in San Francisco with kitchenette. Located in San Francisco's NoPa area which provides some of the best restaurants and bars in the city as well as close access to the outside spaces of the Panhandle and Golden Gate Park. The studio is located on a quiet street which is a 5 minute walk from the NoPa restaurants and Bi-Rite on Divisadero, 7 mins walk from Alamo Square and 15 mins walk from Golden Gate Park

Popular amenities for South San Francisco hotels

Quick stats about hotels in South San Francisco

  • Total vacation rentals

    Explore 50 vacation rentals in South San Francisco

  • Nightly prices starting at

    South San Francisco vacation rentals start at G$71,100 GYD per night before taxes and fees

  • Verified guest reviews

    Over 250 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 40 rentals that welcome pets

  • Vacation rentals with a pool

    20 properties feature pools

  • Rentals with dedicated workspaces

    50 properties have a dedicated workspace

  • Wi-Fi availability

    50 of South San Francisco vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across South San Francisco rentals

Destinations to explore