
Hotels in South San Francisco
Find and book unique hotels on Airbnb
Quick stats about hotels in South San Francisco

Total vacation rentals
Explore 70 vacation rentals in South San Francisco

Nightly prices starting at
South San Francisco vacation rentals start at G$20,920 GYD per night before taxes and fees

Verified guest reviews
Over 480 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Vacation rentals with a pool
30 properties feature pools

Rentals with dedicated workspaces
60 properties have a dedicated workspace

Wi-Fi availability
70 of South San Francisco vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across South San Francisco rentals
Top-rated hotels in South San Francisco
Guests agree: these hotels are highly rated for location, cleanliness, and more.

Harbor Court Hotel, Deluxe one queen
Treat yourself to a relaxing stay in our queen room, featuring a plush queen bed with luxury linens for ultimate comfort. Enjoy thoughtful amenities like a refrigerator, remote control television, and a well-appointed bathroom. With daily maid service, interior corridor access, and a convenient telephone, every detail is designed to create a cozy and restful retreat for two.
4.7 out of 5 average rating, 56 reviews
1 king 1 sofabed suite
The 1 king 1 sofabed suite is non-smoking, service-animal friendly, and offers extra space with a king bed and a sofa bed. Ideal for longer stays, this suite accommodates up to four adults and features air conditioning, heating, refrigerator, microwave, ironing board, desk, LCD/LED TV with cable, direct dial phone, alarm clock, and sofa for added comfort.
4.7 out of 5 average rating, 33 reviews
1 queen with sofa bedroom
Enjoy comfort and convenience in our rooms, located above ground floor and easily accessed by elevator. Each features a private bathroom with a tub or shower, cable TV, direct-dial phone, plus handy amenities like a mini-refrigerator, microwave, and complimentary in-room coffee-designed for a relaxing, carefree stay.
5.0 out of 5 average rating, 4 reviews
Deluxe double room with two double beds
The deluxe double room with two double beds features a seating area, desk, and coffee machine. Amenities include AC, wifi, TV with cable channels, safe, wardrobe, and ironing facilities. The private bathroom offers a bathtub, shower, hairdryer, and complimentary toiletries for a comfortable stay.
4.68 out of 5 average rating, 74 reviews
Well and away king room
Well and away king room features a king bed, a walk-in shower, an oversized desk, an in-room safe, an iron, air conditioning, and wifi. A sustainability-focused room with mindful wellness amenities in collaboration with Casper, Dyson, Peloton, Method, and Muse. Pet-friendly and non-smoking.
4.79 out of 5 average rating, 28 reviews
King room
A king room invites you into a sophisticated San Francisco urban retreat designed to impress. We offer pillow-top mattress, complimentary high-speed internet, flat-screen TV, work desk with lamp, bathtub, minibar, and an en suite bathroom with upgraded amenities.
4.83 out of 5 average rating, 639 reviews
Petite superior king bed- experience the charm
Intimate yet elevated, our petite superior room is perfectly designed for comfort with a plush king bed, sleek workspace, and seamless Wi-Fi. Enjoy a cozy retreat that offers everything you need for a stylish, effortless stay-no detail overlooked.
4.62 out of 5 average rating, 379 reviews
Deluxe king room
This room features a king bed and a thoughtfully designed bathroom with luxury spa bath amenities in warm neutral tones. Guests enjoy courtyard or exterior city views, free wifi, electric bicycle rentals, Peloton bikes, and lobby board games.
4.56 out of 5 average rating, 32 reviews
Queen Room
- Central location near Union Square. - Beautifully decorated rooms rock Japanese-inspired style, plush pillowtop beds and flat-screen TVs. - Other perks include an onsite car rental joint and a dog run (to name a few).
4.86 out of 5 average rating, 99 reviews
The Ameswell Hotel, Selected by hotel
Room will be assigned at check-in based on availability. All rooms offer comfortable accommodations with standard amenities and have a maximum occupancy of 2 guests. Specific features may vary by room.
4.92 out of 5 average rating, 39 reviews
Stanyan Park Hotel, Selected by hotel
Room will be assigned at check-in based on availability. All rooms offer comfortable accommodations with standard amenities and have a maximum occupancy of 2 guests. Specific features may vary by room.
4.79 out of 5 average rating, 148 reviews
Villa Montes Hotel, Selected by hotel
Room will be assigned at check-in based on availability. All rooms offer comfortable accommodations with standard amenities and have a maximum occupancy of 2 guests. Specific features may vary by room.
5.0 out of 5 average rating, 3 reviewsPopular amenities for South San Francisco hotels
Family-friendly hotels

Easy jaunt to the famed cable cars of Union Square
4.64 out of 5 average rating, 268 reviews
Street Facing Three Bed Family Room (No Pets)
4.89 out of 5 average rating, 9 reviews
Queen room
4.64 out of 5 average rating, 209 reviews
Deluxe king room
4.63 out of 5 average rating, 8 reviews
Selected by hotel
4.64 out of 5 average rating, 1035 reviews
One Double Bed
4.67 out of 5 average rating, 12 reviews
Deluxe queen room with fireplace
4.9 out of 5 average rating, 59 reviews
Full bedded room
5.0 out of 5 average rating, 5 reviewsHotels with a pool

Handlery Union Square Hotel, Selected by hotel
4.54 out of 5 average rating, 97 reviews
Deluxe two queen beds
4.61 out of 5 average rating, 105 reviews
Room with 2 beds
5.0 out of 5 average rating, 4 reviews
Deluxe king courtyard
4.64 out of 5 average rating, 45 reviews
Shashi Hotel Mountain View, an Urban Resort, Sele.
4.87 out of 5 average rating, 68 reviews
Deluxe king
New place to stay
Deluxe two doubles
4.78 out of 5 average rating, 9 reviews
Deluxe two doubles
4.5 out of 5 average rating, 4 reviewsOther hotel vacation rentals

Petite suite
5.0 out of 5 average rating, 3 reviews
Starlet queen
4.82 out of 5 average rating, 11 reviews
Deluxe king
4.8 out of 5 average rating, 96 reviews
Argonaut Hotel, a Noble House Hotel, Selected by .
4.7 out of 5 average rating, 56 reviews
Room with 1 bed
4.57 out of 5 average rating, 14 reviewsDestinations to explore
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