
Hotels in South San Francisco
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Top-rated hotels in South San Francisco
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Rock Roulade Cocoon
Your own space/ no shared rooms, easy access ground floor and convenient location. This unique place has a fresh style all its own. Formally a secret famous recording studio for pop-rock bands, it was known as “The Hearst”. World famous records by the Killers were made here, “Hot fuss” and “Sawdust”. The first room, (now bedroom) was the control room with recording equipment and the second room (now tub room) was where the musicians played. Welcome pets for a fee if $35/per pet -per night.

Sophisticated Stay | Cable Cars Tours. Gym
Located on Market Street, Hyatt Regency San Francisco Downtown SOMA is a sophisticated destination hotel close to the city’s most innovatively stimulating sights. Attractions are just nearby: ✔Picturesque picnics at Golden Gate Park ✔Contemporary and modern paintings, photographs, sculptures and designs from the 20th century, all housed at SF MOMA ✔Postcard-worthy shots, at Golden Gate Bridge ✔Beaux-Arts wonder, the Palace of Fine Arts ✔Best views of San Francisco at Twin Peaks

Elegant Noe Valley/Glen Park private suite
Elegant private suite in the Noe Valley/Glen Park neighborhood of San Francisco on a quiet, safe street convenient to transport (J Church Streetcar, 24 Muni bus, BART), restaurants and shopping. Private entrance, queen size bed, high fidelity entertainment system, private white marble bathroom w/ shower and soaking tub, private office with desk and printer; refrigerator, microwave and coffee maker. Free parking on quiet street. Ideal for couples who like to walk. Infants permitted.

San Francisco Suites Studio lll on Nob Hill
Experience true hospitality in an Edwardian setting that is filled with European paintings,antique furniture,crystal chandeliers and a full service kitchen in every suite. You can also have your coffee upstairs in the gazebo overlooking the City. In the afternoon wine,cheese and crackers are served in the lobby and sherry is offered in the evening in front of the fireplace. The concierge will make your dinner reservations and when you depart, the cable car awaits on Powell Street.

Union Square Stay | On Site Restaurant & Bar
Steps from San Francisco’s vibrant Union Square, The Marker blends over a century of hospitality with modern elegance. This boutique Beaux-Arts hotel offers curated amenities like PATH water bottles, FloWater stations, and a 24- hour state-of-the-art fitness center. Dine at Tratto, serving rustic Italian dishes and craft cocktails. With concierge service, curbside valet parking, and California Green Lodging certification, The Marker pairs timeless charm with contemporary comfort.

Book-filled Writer’s Alcove in the lobby
Channeling the spirit of the Beat Generation, every room at Hotel Emblem is a creative retreat featuring a writing desk with an inspiration board. Enjoy plush pillowtop beds with Italian linens, a 55" HD TV, and unique touches like a meditation bowl, typewriter, and coloring books. Thoughtful amenities include in-room coffee and tea, ROIL bath products, and high-speed internet. With pet-friendly options and hotel bikes, your San Francisco stay is both inspiring and comfortable.

Bay Area Escape | Hotel Room. Free Breakfast
If you plan to explore the Bay Area, The Millwood Inn & Suites is a great jumping-off point. This quaint hotel is located in Millbrae, California, only minutes from Bay Area attractions such as the Golden Gate Bridge. It is also only a six-minute drive from San Francisco International Airport, perfect for those flying in! Be welcomed into a world of comfort and convenience after a long day of exploring California's best. ✔ Free breakfast ✔ Free parking ✔ Fitness center

Fun Respite | Happy Hour. Game Room. Pet Friendly.
Axiom Hotel, a 4-star establishment in San Francisco's city center, is an ideal accommodation for those looking for a fun hotel to stay in during their trip to SF. It features a fitness center and a game room. Guests can also venture out to see prime attractions nearby, like Moscone Center and the Ferry Building. ✔ Fitness center ✔ Robot-delivered room service ✔ Pet-friendly ✔ Arcade games ✔ Cafe on-site ✔ Breakfast, lunch, dinner, boba and a full bar

Monroe Studio 325
The Monroe Residence Club is a residential hotel located centrally in the heart of San Francisco with public transportation at our doorstep and local shops and businesses nearby. It is conveniently located just a block from Whole Foods, blocks from a the iconic Lafayette Park, within walking distance of several hospitals and more! The Monroe offers 24-hour front desk security, breakfast and dinner on-site, as well as common areas for congregating.

King Bed at Shashi Hotel in Mountain View
Experience our King room type at Shashi Hotel Mountain View, an Urban Resort. Conveniently, located in the heart of the Silicon Valley - walking distance to Shoreline Amphitheatre. Taste incredible cocktails and delicious bites at our Emerald Hour Bar designed by our Michelin-rated Chef. Enjoy complimentary amenities including our outdoor pool, fitness center, sauna and steam rooms. New for 2025 - daily wine tasting, yoga, zumba, and live music.

1 Bedroom Apartment Nob Hill Inn
This 1-bedroom apartment with a living room in the heart of Nob Hill offers the perfect blend of comfort and convenience. What makes this space special is the combination of privacy and space, featuring a separate living area for relaxation and a well-appointed bedroom for restful nights. Located in the prestigious Nob Hill neighborhood, you’ll be steps away from top San Francisco attractions, iconic landmarks, and local dining gems.

Boutique large studio in NoPa San Francisco
Self-contained large studio in San Francisco with kitchenette. Located in San Francisco's NoPa area which provides some of the best restaurants and bars in the city as well as close access to the outside spaces of the Panhandle and Golden Gate Park. The studio is located on a quiet street which is a 5 minute walk from the NoPa restaurants and Bi-Rite on Divisadero, 7 mins walk from Alamo Square and 15 mins walk from Golden Gate Park
Popular amenities for South San Francisco hotels
Family-friendly hotels

Single Bed in 4 Bed Female Capsule Room

1 Bed Female Dorm w/Private Bath

Bold, boho hideaway in the heart of the city

Near Oracle HQ | Free Breakfast + Full Kitchen

One Full Sized Bed in Dorm Not Private

Classic King Bed at Grand Bay Hotel San Francisco

2 Queen Beds | Near Airport. Pool. Free Breakfast

Cozy room with private entrance and bathroom
Hotels with a pool

Bright Studio Suite King Bed with Kitchen

Berkeley Double Bed with Garden View | Indoor Pool

Guild & Pepper bath amenities & courtyard views

Near Santana Row & San Jose Convention Center

Sleek, classic rooms in heart of SF

Near Stanford Univ + Breakfast. Kitchen. Pool.

Near Hacienda Business Park + Pool. Fitness Center

Chic Asian-inspired Ambiance in Union Square!
Hotels with a patio

1 Br Ritz-Carlton San Francisco

Club Wyndham Suites at Fisherman’s Wharf

Unique Hotel Inn at the Opera

Central SF Studio Perfect for Exploring the City

PodShare SF Marina - Queen pod - Sleeps 1 or 2!

Courtyard Room with Queen Bed in Central Oakland

Stylish 1 Bedroom at Fisherman's Wharf!

1 King bed in boutique hotel
Quick stats about hotels in South San Francisco

Total vacation rentals
Explore 50 vacation rentals in South San Francisco

Nightly prices starting at
South San Francisco vacation rentals start at G$71,100 GYD per night before taxes and fees

Verified guest reviews
Over 250 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 40 rentals that welcome pets

Vacation rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
50 properties have a dedicated workspace

Wi-Fi availability
50 of South San Francisco vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across South San Francisco rentals
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