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Luxury rentals in South America

Luxury rentals in South America

Find and book unique accommodations on Airbnb

Top-rated luxury vacation rentals in South America

Guests agree: these stays are highly rated for location, cleanliness, and more.

Diosa del Mar
LUXE
Entire villa · 10 guests · 5 beds · 5 baths

Diosa del MarTropical artists' estate overlooking the sea

Villa Oceanis
LUXE
Entire villa · 4 guests · 2 beds · 2 baths

Villa Oceanis

Casa Ramon
LUXE
Entire villa · 14 guests · 8 beds · 11 baths

Casa RamonCasa Ramon

Luxury rentals for every style

The right home for your next dream getaway

  • Featured Homes
  • Flexible bookings
  • Ready to book homes

Popular amenities for South America luxury vacation rentals

  • Kitchen
  • Wifi
  • Pool
  • Free parking on premises
  • Air conditioning
  • Gated property

Other great luxury vacation rentals in South America

Little Waters on the Cliff
LUXEEntire villa
Little Waters on the Cliff
Price:GYD209,076 / night
Four Winds
LUXEEntire villa
Four Winds
Price:GYD418,152 / night
Mumbai
LUXEEntire villa
Mumbai
Price:GYD253,818 / night
Sweet Spot
LUXEEntire villa
Sweet Spot
Price:GYD604,827 / night
Grand Bleu
LUXEEntire villa
Grand Bleu
Price:GYD328,667 / night
Happy Bay Villa
LUXEEntire villa
Happy Bay Villa
Price:GYD267,408 / night
Lune de Miel
LUXEEntire villa
Lune de Miel
Price:GYD164,334 / night
Villa Don Vito
LUXEEntire villa
Villa Don Vito
Price:GYD200,115 / night
Villa Paraiso - Manuel Antonio
LUXEEntire villa
Villa Paraiso - Manuel Antonio
Price:GYD519,762 / night
Canoe Cove
LUXEEntire villa
Canoe Cove
Price:GYD808,496 / night
Fortlands Point on Discovery Bay
LUXEEntire villa
Fortlands Point on Discovery Bay
Price:GYD776,508 / night
Turtle Nest
LUXEEntire villa
Turtle Nest
Price:GYD462,894 / night