
House vacation rentals in Shem Creek
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Top-rated house rentals in Shem Creek
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The Darby House / Beach / Shem Creek / Old Village
Welcome to The Darby House! The Darby House is a luxurious 4 bedroom home located in a family-friendly neighborhood backing up to Charleston's Shem Creek Waterway. Only a short walk to the Old Village District, local shops, restaurants, bars, or a bike ride to Sullivan's Island Beach! Newly built 4BR/3.5BA house with new TVs in each room. Amazing entertainment space with a fenced-in front yard, outdoor patio, corn hole, and grill area. MP STR Permit: ST260104; Business License: BL-24-011322
LocationFamilyWifi
4.98 out of 5 average rating, 147 reviews
Charming Old Village Retreat Fenced Yard ShemCreek
Experience The Old Village Retreat, a cozy ranch house in historic Old Village, Mount Pleasant. This charming 3-bedroom, 1.5-bath home comfortably fits a group, offering a modern kitchen, fenced yard, fire pit, and screened porch with outdoor dining. Steps from Shem Creek and minutes to beaches, it's perfect for a pet-friendly Lowcountry escape. Enjoy tranquil live oaks and easy access to dining, shops, and coastal adventures. Mount Pleasant STR Permit #ST260154 Business License: BL-24-003896
ValueFamilyIndoor spaces
4.9 out of 5 average rating, 426 reviews
Coastal Farmhouse Comfort
Freshly updated house tucked in a quiet neighborhood 1/2 way b/t Sullivan's Is. & Shem Creek. Covered back patio: 55 in smart tv, comfy chairs, gas fire pit, gas grill, dining table, mounted fans to keep you cool and the bugs away. Beach chairs/towels/umbrella included. Bring your dogs! No cats. Large fenced back yard with doggie bags & a hammock by the banana trees! Open floor plan, fully stocked kitchen and outdoor shower! Mt Pleasant business license # bl-24-012302 str permit ST260297
LocationFamilyComfort
4.91 out of 5 average rating, 211 reviews
Old Village 2bd Home, Near Sullivans + Downtown!
Tucked beneath the oaks in Mount Pleasant's beloved Old Village, this inviting retreat is the perfect place to slow down and experience the Lowcountry at its best. Thoughtfully designed with bright, welcoming spaces and plenty of room to unwind, it's ideal for couples, families, or friends. Spend your days exploring waterfront parks, hopping on the ferry to downtown Charleston, dining at neighborhood favorites, or relaxing at nearby beaches before returning to your own peaceful escape.
FamilyLocationAir conditioning
4.96 out of 5 average rating, 135 reviews
Lowcountry Oasis - 3 bed/2 bath - 5 min to beach
Relax here with the whole family and experience the charm of Charleston! With room to spread out, you'll quickly feel at home in this quiet little neighborhood - whether relaxing in the lounge chairs on the backyard patio or exploring all the greater Charleston area offers. You'll find this location has quick access to the beaches, boat landings, Shem Creek restaurants, and historic downtown Charleston. It's the perfect stay for your trip to the Lowcountry. #ST260103/ BL#24-024983
LocationFamilyOutdoor spaces
4.92 out of 5 average rating, 193 reviews
Old Village - 3 BR with Private Backyard & Deck
Discover the ultimate Charleston experience in the heart of Old Mt. Pleasant! Immerse yourself in the vibrant energy of this fully renovated, adorable house. Nestled conveniently close to pristine beaches, just steps away from restaurants, and very to to historic Downtown Charleston. This rental is your gateway to a quintessential Lowcountry adventure. Don't just visit Charleston—live it, love it and make unforgettable memories at this delightful retreat! Your adventure begins here!
ValueFamilyView
4.9 out of 5 average rating, 126 reviews
Relax at a Cozy Home Between the Best Beaches and Downtown
Relax year round in this bright sunny space. Grill in the backyard and make s'mores in the fire pit! Cozy up to the fireplace. Fix a delicious meal in the fully equipped kitchen. Town of Mt. Pleasant Business license number: 24001197 STR Permit number: 250289 The house is in a traditional family neighborhood in south Mount Pleasant with tall trees and low traffic. Many great restaurants are at Shem Creek, with beaches, town center and Boone Hall Plantation within 15 minutes.
ValueFamilyLong stay
4.91 out of 5 average rating, 307 reviews
Luxurious Artist's Home
Located within minutes to world-class restaurants, beaches and historic downtown, this home features the perfect combination of elegance, art and southern charm. Whether escaping for a getaway, seeking leisure, or looking for a fun-filled vacation, this home is perfect. Enjoy a private sauna, a 72" clawfoot tub, plush towels, luxurious beds, a well-appointed kitchen, surround sound, HD TV, streaming services, outdoor living and original art. ST permit ST260123 BL-24-005864
FamilyValueGetting around
4.97 out of 5 average rating, 126 reviews
Randall Cottage - 3miles to Sullivans Island Beach
Quiet, safe, private family friendly neighborhood 5 minutes to beach & 15 minutes to Historic Downtown Charleston. Completely remodeled, all new appliances, bathrooms & flooring. Spacious screen porch with ample seating, dining area, couch & TV. Fenced in back yard with picnic table, cornhole boards, and outdoor grill area. Plenty of off-street parking! 2 master bedrooms with king size beds and private baths. 2 bedrooms with queen beds, tv's in all bedrooms and living room.
FamilyValueBiking
4.99 out of 5 average rating, 194 reviews
Upscale EARL CRT 3-bdrm Old Village/Shem Creek
STR PERMIT #ST250176 BUSINESS LICENSE #20135982 3-bdrm Earl's Court neoclassical upscale home, nestled in the heart of the historic Old Village, offering the charm of low country living. Just a block from Shem Creek bars & restaurants, Old Village shops & eateries, Alhambra Hall, Pitt St Bridge, and a weekly all food Farmer's market, featuring low countries finest! The Arthur Ravenel Bridge, downtown Charleston, Sullivan's Island & IOP beaches are all bike riding distance.
ValueFamilyParking
5.0 out of 5 average rating, 283 reviews
Palmetto Grove, Walk to Shem Creek, Mins to Dwt
BOATERS WELCOME! Palmetto Grove is a brand new, spacious and beautifully decorated 4 Bed, 4 Bath home located a short walk away from Shem Creek and a 5 minute drive to downtown Charleston. Palmetto Grove is the perfect vacation rental for a family or large group and can sleep up to 10 guests. Cook and dine in the newly updated chef's kitchen. Enjoy the private backyard, patio, grill, outdoor table and fire pit. Enjoy the ultimate vacation!
FamilyLocationCleanliness
4.98 out of 5 average rating, 125 reviews
Mt Pleasant Cottage-Downtown, Shem Creek & Beaches
Make the most of your visit to Charleston by staying at this fully renovated cottage in the heart of Mount Pleasant! This property offers an open floor plan, deck area, and spacious backyard. Conveniently located just minutes away from Shem Creek, Downtown Charleston, Isle of Palms, Sullivans Island, and a variety of restaurants/shopping! -12 mins to Isle of Palms -13 mins to Sullivans Island -12 mins to Shem Creek -14 mins to Downtown
FamilyValueWalkability
4.99 out of 5 average rating, 136 reviewsPopular amenities for Shem Creek house rentals
House rentals with a pool

Pristine Townhouse - Beach, Charleston, Pool, Fun
LocationValueView
4.94 out of 5 average rating, 135 reviews
Pura Vida, minutes to Beaches, w/a Pool!
LocationValueHospitality
4.98 out of 5 average rating, 191 reviews
Coastal Family Getaway, Heated Pool
FamilyValueAccess
4.94 out of 5 average rating, 291 reviews
Pleasant Place New Build + Pool Great for Families
LocationValueTV
4.89 out of 5 average rating, 178 reviews
Gorgeous home one block from beach w/ heated pool
FamilyValueAccuracy
4.97 out of 5 average rating, 118 reviews
12 Duplex w/Shared POOL, Great Location ST260389
FamilyLocationSleep quality
4.89 out of 5 average rating, 164 reviews
Mount Pleasant oasis near beach with private pool!
LocationFamilyParks
4.93 out of 5 average rating, 129 reviews
Coastal Cottage in Charming Old Mt Pleasant
LocationValueParking
4.92 out of 5 average rating, 162 reviewsWeekly house rentals

Trendy, Modern House Close to Beaches & Downtown
ValueLocationCheckout
4.97 out of 5 average rating, 298 reviews
The Mallard's Nest
ValueFamilyParks
4.92 out of 5 average rating, 130 reviews
Palmetto Getaway! Walk & Bike Side B
FamilyValueBiking
4.96 out of 5 average rating, 255 reviews
Mt Pleasant Central location Dog friendly Fenced
FamilyLocationNearby
4.91 out of 5 average rating, 141 reviews
Claudia's Home: Entire Home Rental Near Beaches
ValueFamilyWalkability
4.97 out of 5 average rating, 163 reviews
10 Minute Drive To Beaches | The Wishing Well
FamilyValueGrill
4.94 out of 5 average rating, 158 reviews
3 Miles to Sullivan’s Island | Private Yard
FamilyLocationAccuracy
5.0 out of 5 average rating, 168 reviews
Sea Breeze
FamilyValueDecor
4.99 out of 5 average rating, 124 reviewsPrivate house rentals

Rockin’ Robin - Family sized great location!
LocationFamilyIndoor spaces
5.0 out of 5 average rating, 138 reviews
Walk to Dining, Coffee. Ping Pong, Bikes, Fire Pit
FamilyLocationOutdoor spaces
4.98 out of 5 average rating, 206 reviews
Coastal Retreat-4B/2B 9ppl 3 mi to IOP fenced yard
LocationValueCheckout
4.97 out of 5 average rating, 144 reviews
Pet Friendly&Fenced Yard Near Beaches & Downtown!
LocationFamilyBackyard
4.98 out of 5 average rating, 166 reviews
peaceful, modern retreat near beaches and downtown
FamilyValueSleep quality
4.91 out of 5 average rating, 203 reviews
Babington Way Getaway 4 King beds
LocationValueBackyard
4.86 out of 5 average rating, 357 reviews
Dog Friendly Home with Fenced Yard | Chic Coastal
ValueFamilyCondition
4.9 out of 5 average rating, 209 reviews
Quaint Quarters in the heart of Mount Pleasant
ValueFamilyParks
4.9 out of 5 average rating, 178 reviewsDestinations to explore
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- Sullivan's Island Beach
- Isle of Palms Beach
- Hunting Island State Park Beach
- Charleston City Market
- Bulls Island
- James Island County Park
- College of Charleston
- North Charleston Coliseum & Performing Arts Center
- Waterfront Park
- Rainbow Row
- Riverfront Park
- Shem Creek Park
- Magnolia Plantation & Gardens
- Hampton Park
- Edisto Beach State Park
- The Charleston Museum
- Middleton Place
- Hunting Island State Park
- White Point Garden
- Angel Oak Tree
- Kiawah Beachwalker Park
- Cypress Gardens
- Boone Hall Plantation
- Gibbes Museum of Art





