
Vacation rentals in Semmes
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Top-rated vacation rentals in Semmes
Guests agree: these stays are highly rated for location, cleanliness, and more.

Downtown , Modern Spacious & Near I-10
Enjoy a little piece of Mobile, Alabama by staying at this centrally located townhouse near all the best restaurants and the hustle and bustle of downtown. This unique space is a minute from I-10 giving you easy access to the interstate and quick driving time to just about anywhere. Minutes from the convention center, cruise terminal, Washington Square, and the famous Callaghan's Irish Social Club. Spacious, clean, modern, and convenient are all descriptions for this cute, newly remodeled space.

Cozy Home Minutes to Downtown
RELAX & UNWIND at this PEACEFUL, SPACIOUS & COZY Cottage located in the popular Midtown area of Mobile! Upon arrival you will feel right at home. You will find this cottage is very spacious equipped with a King size bed, Queen size bed, Full size bed, Master bathroom & Guest bathroom & a fully equipped kitchen! Enjoy a glass of wine, a good book or some family time outback in the peaceful backyard! A short commute to all the restaurants, bars & attractions! This cottage is the perfect getaway!

The Bare Minimum Bachelor Pad 3 bed/2 baths
If you're looking for simplicity and comfort without the frills, you've found the perfect spot! Located in Semmes, Al near mobile. This 3-bedroom, 2-bath retreat is all about the basics, offering just what you need for a laid-back stay. No fuss, no clutter, just space to relax, recharge, and enjoy the essentials. With no distracting art on the walls or extra knick-knacks, this place is perfect for anyone who appreciates clean lines and an "everything-you-need-and-nothing-you-don't" vibe. 😊

Charming Midtown • Walkable • Easy DT Access
Centrally located in charming, walkable Midtown Mobile’s Old Dauphin Way Historic District, my home is just minutes from: 🎭 Mardi Gras parade route (2 mi), USS Alabama (5.3 mi), GulfQuest Museum (2.8 mi), Saenger Theatre (2.6 mi), LODA District (2.6 mi), Ladd-Peebles Stadium (0.8 mi), and Convention & Civic Centers (2.9 mi). 🏥 Near USA Health (2.5 mi) & Mobile Infirmary (3.2 mi). 🏖️ Dauphin Island (45 mins). ✈️ 15 mins to Mobile Regional Airport with quick access to I‑10/I‑65.

Three Notch Cutie
Your family will be close to everything at this centrally located home located in the Tillman's corner area of Mobile, AL. The house is approximately 1/4 mile from a new Dollar General and 3 miles from interstate I-10. In 2024 we did an interior renovation of the house, so that it now features LED lighting, freshly painted walls, new floors, new appliances, a tile shower, granite countertops, and brand new furniture. We ask that you take care of our investment. Thank you!

Oakleigh Efficiency Studio private entry Weekly
Our private entrance cottage is a one bedroom,bath, self contained unit with a kitchenette with a microwave, coffee pot, toaster, undercounter fridge, dishes, glasses and cooking utensils.There is a full size bed, SmartTV, love seat and computer desk space. Wonderful back deck for sunny afternoons or evening cocktails. Private entrance with keyless entry. On street parking with security lighting in wonderful walking neighborhood. Owners unit attached at front of property

Peaceful Backyard Suite
Enjoy the sounds of nature when you stay in this unique place. Shade trees can be seen through the fixed windows near the cathedral ceiling. Feels as though you are in a treehouse! Bedroom has one queen bed & can be closed off from kitchen & living room. House is new and within a fenced yard. It’s to the rear of owner’s home and backs up to a flower nursery. Very quiet. Great place to study, work online, or just relax. Swing on Front Porch. Pets for short term. No cats.

Updated historic home w/ fast Wi-Fi near downtown
Beautifully renotaved historic home in Oakley Garden Historic District. Located within walking distance or a short ride to downtown, the Mardi Gras Parade, and all the popular restaurants and attractions. Within 5-minute walking distance to the popular Callaghan's Irish Social Club (best burger in Mobile and recently voted the best bar/social club in the South!), The Hummingbird Way Oyster Bar or the popular Washington Square Park. Experience the magic of Mobile!

Cozy South Alabama Home
Your family will be close to everything when you stay at this centrally-located place. Minutes from South Alabama (USA), Springhill College, Mobile Tennis Center, parks, golf, Mobile Art Museum, Fair Grounds, and much more. The home sits on a large lot easy to find. Large fenced back yard for you and your four legged family members to enjoy. Also has a large covered back deck to enjoy along with a gas grill. Walking distance to the park and Japanese’s garden.

{BOHO}Stylish Stay + King Bed
Please take a few minutes to read our reviews and hear why guests love our place so much... we work hard to provide a five star experience for every single guest we host. We know you will love it too! Our duplex is situated in a very friendly walkable neighborhood. Starbucks is just a short walk down the street. Walking distance to Aldi, Guncles gluten free bakery, and Soul Caffeine coffee shop.

Haven on Hamilton
Cozy, private guest suite convenient to the interstate, airport and great local restaurants. Located just half an hour from Dauphin Island and historical downtown Mobile. Local attractions include the USS Alabama, Mobile cruise terminal, and more. You can have the quiet, country feel with all the convenience of city living.

The Oak Haven - Ideal for Remote Work & Pets!
This unit is available for 1 month MINIMUM stays Welcome to The Oak Haven at Summerville Court, a cute & cozy historic condo! Be sure to checkout some highlights of the house, including the detailed guidebook and wall art that features local shops and restaurants! We are 5.0 Star Superhosts and look forward to hosting you!
Popular amenities for Semmes vacation rentals
Other great vacation rentals in Semmes

Fearless Travel Escape

The Banana Shotgun House

Happy Camper, Large 2 bedroom camper.

Near Airport : Mobile, AL. #2

Stay at The Pearl - Midtown Gem

MasterSuite w/ Private Entry and Bathroom

Spacious home with pool and large yard

County living#1
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