
Vacation rentals in Santa Panagia
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Top-rated vacation rentals in Santa Panagia
Guests agree: these stays are highly rated for location, cleanliness, and more.

Maisonette, 14 San Paolo
Maisonette San Paolo 14, an extremely elegant suite, is located in a historic 17th-century building adjacent to the Temple of Apollo, following a meticulous renovation focused on comfort and design. As soon as you enter, you are enveloped by a positive energy that conveys serenity and harmony, perfect for relaxing. Equipped with a kitchen, an en-suite bedroom, and a stylish outdoor patio for enjoying unforgettable moments. The intimate atmosphere of this residence makes it ideal for couples and for the most discerning guests.

The Terrace over the Ancient Market of Ortigia
Charming home over the ancient market of Ortigia. This apartment offers a private terrace with stunning views of Ortigia and the sea. The modern and high-end design makes this accommodation unique. The Market is the most authentic place on the island of Ortigia, where the scents and flavors of yesteryear still find their perfect expression today. The apartment offers a bedroom with balcony and en-suite bathroom, a large living room with balcony, an open concept kitchen and an additional bathroom

Penthouse Lady Packard
Lady Packard’s Penthouse just had a glow up!✨ A stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.

Allisola Country Villa - casa Carrubo
Allìsola è un'antica residenza siciliana, immersa nella splendida area protetta del Plemmirio, a pochi km da Siracusa. Da un unico corpo sono state ricavate tre raffinate case, indipendenti fra loro, inserite in un unico grande spazio esterno con angoli verdi, terrazze e una rilassante piscina. A disposizione degli ospiti c’è una terrazza privata con arredamento per esterni, un grande giardino con piscina in condivisione con gli ospiti della struttura e un parcheggio immerso in un uliveto

One step to Ortigia! Bicycles & Balcony
Bright and stylish renovated flat just steps from the city center and Ortigia—you can walk to all the must-see spots with ease. Cozy and welcoming, it’s the perfect home base for your holiday in Sicily! ☀️ Sunny balcony for relaxing moments en plein air 🚲 FREE bicycles available throughout your entire stay 🚗 Hassle-free street parking – and it’s free 24/7! We also have two more apartments in the same building—check out my profile to discover them and read our glowing 5-star reviews!

Sea-View Loft. Stylish, Spacious and Comfortable
Experience the magic of Ortigia in this elegant, thoughtfully designed 80m² apartment that blends charm, comfort, and relaxation. Ideal for couples or small groups, it is located just steps from the island’s most iconic sights. Enjoy a stunning sea view balcony, a bright living area complete with a sofa bed, a fully equipped kitchen, a cozy bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, and heating. For your convenience, the building is served by an elevator.

Casa Coco•Palma•Sea View apt. - from 2 to 4 guests
Welcome to Casa Coco Palma, a stylish two-bedroom apartment with breathtaking sea view. IMPORTANT: IF BOOKED FOR 2 PEOPLE THE SECOND BEDROOM WILL BE CLOSED. This is Sicilian coastal living at its pinnacle: your front-row seat to the Ionian Sea, where the salty breezes blend with the gentle sound of waves. Work in a serene dedicated space. Then unwind on your private balcony for morning espresso while watching Ortigia island, or a local glass of wine as sailboats drift by.

Casa Sirokos
Casa Sirokos is a detached villa facing the pool, surrounded by the greenery of the most scenic residential neighborhood in Syracuse. It features local architecture that blends with large outdoor spaces and gardens typical of the Sicilian countryside. The cottage is one of two independent accommodations that are part of this property, which also offers an apartment located on the second floor of an ancient manor house. The sophisticated and relaxing atmosphere sets us apart!

Light and Relaxation: Large Open Space on the Garden
Located in a private wing of the villa with a separate entrance, this 95-square-meter open space combines refinement and modernity. The large windows flood the rooms with natural light, while the decor naturally defines the different areas. A perfect balance between design, comfort and nature: the spaces blend harmoniously with the garden, creating relaxation and privacy. For safety and comfort reasons, the property only accommodates children aged 10 and over.

Agàpe Ortigia
Agàpe Ortigia is an accommodation created with Love in the magical island of Ortigia, in the historic center, a stone's throw from the Duomo and the major sites of interest. The independent room is large and spacious, has a double bed, TV, free Wi-Fi, tea and coffee corner, but the peculiarity of this accommodation apart from the furnishings is the bathroom which, in addition to having the main amenities, offers a large sunken tub where you can relax.

Casa Salgiò
Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.

Arianna's home
The recently renovated house is a short walk from the Lungomare and the typical open-air market. The double bedroom has a lovely balcony overlooking the main street, ideal for a glass of wine at the end of a long day of vacation. The kitchen allows you to eat at home comfortably, a pleasant sea breeze enters from the window that opens onto the ronco. All the must-see places in Ortigia are within walking distance, as is Calarossa beach
Popular amenities for Santa Panagia vacation rentals
Other great vacation rentals in Santa Panagia

MaMi's: Apartment for 2 people

Cortiletto Eveneto

Elegant apartment in the heart of Syracuse.

One-Bedroom Apartment with Terrace

Janco - Villa Amato

Villa with pool + stunning views

Syracuse Ortigia Circe sul Mare

Shati Luxury •Private Pool•Sea View•Walk to Beach
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- Fontane Bianche Beach
- Calamosche Beach
- Etna Park
- Castello Ursino
- Etnaland
- Piano Provenzana
- Teatro Massimo Bellini
- Fondachello Village
- Castello Maniace
- Castello di Donnafugata
- Greek Theatre of Syracuse
- Villa Bellini
- Oasi Del Gelsomineto
- Sampieri Beach
- Isola delle Correnti
- Fishmarket
- Nature reserve of Vendicari
- Museo Emilio Greco
- Spiaggia Vendicari
- Museo Archeologico Regionale Paolo Orsi
- Temple of Apollo
- Necropolis of Pantalica
- Monastery of San Nicolò l'Arena
- Aci Trezza





