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Vacation rentals in Santa Panagia

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Panagia

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A contemporary living space features a plush rug under a sleek dining table surrounded by four velvet chairs. A stylish sofa is positioned beside a modern light fixture, with green plants adding a touch of nature to the room. Large curtains frame the windows, giving a warm ambiance.
Apartment in Syracuse
4.89 out of 5 average rating, 44 reviews

Armonia Market and Sea

Armonia Market and Sea is a luxurious apartment in the historic center. Here, the scents and flavors of yesteryear still find their perfect expression today. The house, with 2 balconies and a splendid sea view, overlooks the most authentic Market of Ortigia. This environment is characterized by the classic “banniate”, so called in Sicilian dialect, as well as harmonious cries of the sellers to draw attention to their local delicacies. The apartment offers 2 bedrooms each with en-suite bathroom

Guest favorite
An outdoor balcony features a small wooden table paired with two white chairs. Potted plants add greenery, while the view showcases nearby buildings against a clear blue sky. Natural light brightens the space, creating a refreshing atmosphere for relaxation.
Apartment in Syracuse
4.96 out of 5 average rating, 265 reviews

One step to Ortigia! Bicycles & Balcony

Bright and stylish renovated flat just steps from the city center and Ortigia—you can walk to all the must-see spots with ease. Cozy and welcoming, it’s the perfect home base for your holiday in Siracusa! ☀️ Sunny balcony for relaxing moments en plein air 🚲 FREE bicycles available throughout your entire stay 🚗 Hassle-free street parking – and it’s free 24/7! We also have two more apartments in the same building—check out my profile to discover them and read our glowing 5-star reviews!

Top guest favorite
A charming balcony is presented, featuring a small round table with a floral centerpiece and two cushioned chairs. The railing offers a view of the serene blue sea and the historic buildings lining the waterfront, creating a relaxing setting for morning coffee or evening drinks.
Condo in Syracuse
4.99 out of 5 average rating, 350 reviews

Sea-View Loft. Stylish, Spacious and Comfortable

Experience the magic of Ortigia in this elegant, thoughtfully designed 80m² apartment that blends charm, comfort, and relaxation. Ideal for couples or small groups, it is located just steps from the island’s most iconic sights. Enjoy a stunning sea view balcony, a bright living area complete with a sofa bed, a fully equipped kitchen, a cozy bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, and heating. For your convenience, the building is served by an elevator.

Guest favorite
A dining area is shown featuring a round table set for a meal with plates, glasses, and cutlery arranged neatly. Six green chairs surround the table. A decorative lamp and two framed artworks are positioned against a light-colored wall, enhancing the space's contemporary appeal.
Apartment in Syracuse
5 out of 5 average rating, 11 reviews

Conmare Lena

Case Conmari, 3 new apartments in a recently restored Art Nouveau building, a stone's throw from Ortigia and close to the city's main attractions: Caravaggio, the Neapolis Archaeological Park, the Paolo Orsi Archaeological Museum. Two apartments of about 80 square meters, consisting of two bedrooms, two bathrooms and a kitchen. An attic apartment of about 60 square meters consisting of two bedrooms and a bathroom ideal for a family. Free cot and extra bed upon request

Superhost
A spacious sleeping area features a large bed with soft green accents and warm wooden flooring. A comfortable chair is positioned beside the bed, and a round rug with leaf patterns adds a touch of nature. Natural light filters in through large windows covered with shades.
Condo in Syracuse
4.8 out of 5 average rating, 5 reviews

Light and Relaxation: Large Open Space on the Garden

Located in a private wing of the villa with a separate entrance, this 95-square-meter open space combines refinement and modernity. The large windows flood the rooms with natural light, while the decor naturally defines the different areas. A perfect balance between design, comfort and nature: the spaces blend harmoniously with the garden, creating relaxation and privacy. For safety and comfort reasons, the property only accommodates children aged 10 and over.

Top guest favorite
The spacious sleeping area features a large white bed positioned against an arched stone wall. Soft lighting highlights the texture of the stones, while decorative elements add a touch of charm. A woven rug lies at the foot of the bed, contributing to the room's cozy appeal.
Home in Syracuse
4.94 out of 5 average rating, 182 reviews

Agàpe Ortigia

Agàpe Ortigia is an accommodation created with Love in the magical island of Ortigia, in the historic center, a stone's throw from the Duomo and the major sites of interest. The independent room is large and spacious, has a double bed, TV, free Wi-Fi, tea and coffee corner, but the peculiarity of this accommodation apart from the furnishings is the bathroom which, in addition to having the main amenities, offers a large sunken tub where you can relax.

Superhost
A modern living area is presented, featuring a flat-screen television mounted on a light-colored wall unit. A dining table with four black chairs is positioned nearby, and a dark area rug is laid on the tiled floor. Soft lighting is provided by exposed bulbs.
Apartment in Syracuse
4.74 out of 5 average rating, 35 reviews

Casa Salgiò

Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.

Top guest favorite
A spacious bedroom features a large bed with crisp white linens against a blue accent wall. Natural light enters through a window with blue curtains, and a flat-screen television is mounted on the opposite wall. A bedside table and a chair enhance the minimalist decor.
Condo in Syracuse
4.96 out of 5 average rating, 265 reviews

Sunny Island 2

Sunny Island 2, let yourself be pampered by the total comfort available in this recently completely renovated apartment, inside a historic building of exclusive ownership. A few meters from the island of Ortigia, the beach and the archaeological area. Here you will find tranquility and well-being to spend a wonderful holiday!! We apply discounts for weekly and monthly stays. TOURIST TAX IS ALREADY INCLUDED IN THE FINAL PRICE

Guest favorite
A softly lit hallway features a framed floral painting above a white console table. A green glass lamp and a small potted plant are placed on the table, while another plant sits nearby on the floor, contributing to a calming atmosphere.
Condo in Syracuse
4.97 out of 5 average rating, 62 reviews

Comfortable apartment with reserved parking space

Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.

Top guest favorite
Home in Plemmirio
4.98 out of 5 average rating, 110 reviews

Casa Francesca

Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.

Guest favorite
A serene garden surrounds a clear blue pool, flanked by lush tropical plants and vibrant flowering bougainvillea. Tall palm trees provide shade, enhancing the peaceful atmosphere of the outdoor space of the property.
Villa in Syracuse
4.9 out of 5 average rating, 172 reviews

Casa Maya nice apartment in villa, private pool

Our house offers a beautiful garden with tropical plants and a big swimmingpool. The apartment consists of 2 bedrooms, a spacious bathroom with tub and shower and a well-equipped kitchen. There is also a babybed if needed, free of charge, please request when booking. There is a wonderful private guest veranda to enjoy as well. Free parking inside the premises.

Guest favorite
A spacious living area is showcased, featuring a comfortable sofa with green accent pillows. A sleek television is mounted on a wooden console, while a dining table is visible in the background. Decorative plants enhance the room's atmosphere.
Home in Syracuse
4.95 out of 5 average rating, 123 reviews

[Elegant] DreamSuite - 300m from Ortigia

-Quality furnishings, comfortable bed and sofa bed - Parking spaces in the area -300m from the historic center - Surrounding area full of bars and restaurants - The house consists of a living area, equipped kitchen and a bedroom - 2 bathrooms with shower - 2 smart TVs - Free Wi-Fi - Fully air-conditioned and soundproofed environment

Popular amenities for Santa Panagia vacation rentals

  1. Airbnb
  2. Italy
  3. Sicily
  4. Santa Panagia