
Vacation rentals in Santa Panagia
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Top-rated vacation rentals in Santa Panagia
Guests agree: these stays are highly rated for location, cleanliness, and more.

Maisonette, 14 San Paolo
Maisonette San Paolo 14, an extremely elegant suite, is located in a historic 17th-century building adjacent to the Temple of Apollo, following a meticulous renovation focused on comfort and design. As soon as you enter, you are enveloped by a positive energy that conveys serenity and harmony, perfect for relaxing. Equipped with a kitchen, an en-suite bedroom, and a stylish outdoor patio for enjoying unforgettable moments. The intimate atmosphere of this residence makes it ideal for couples and for the most discerning guests.

The Terrace over the Ancient Market of Ortigia
Charming home over the ancient market of Ortigia. This apartment offers a private terrace with stunning views of Ortigia and the sea. The modern and high-end design makes this accommodation unique. The Market is the most authentic place on the island of Ortigia, where the scents and flavors of yesteryear still find their perfect expression today. The apartment offers a bedroom with balcony and en-suite bathroom, a large living room with balcony, an open concept kitchen and an additional bathroom

Shati Luxury •Private Pool•Sea View•Walk to Beach
Private heated pool 30°C, all year round. Just a few steps from a pristine white sandy beach Sea view and total privacy. Signature design and refined luxury. An architectural retreat immersed in tropical greenery overlooking the sea. Iconic design, comfort and top-level services. Premium sleep with toppers and a curated pillow menu. Breathtaking sea views and refined finishes. On request: private chef, daily housekeeper, babysitting and tailor-made experiences Signature design by C. Calvagna.

Brand new apartment with patio across Ortigia
Fully renovated modern apartment in proximity of Ortigia (6 mins walk) with free parking. With its three ensuite double bedrooms, the apartment can accommodate up to 6 people. All the rooms have aircon and 32' smart TV as same as the living room equipped with a 50' smart TV, a cozy couch and a few armchairs. A fully equipped kitchen and a patio to enjoy a glass of wine around a wooden table with your family and friends. Never wait around as you can check yourself in with the access code!

One step to Ortigia! Bicycles & Balcony
Bright and stylish renovated flat just steps from the city center and Ortigia—you can walk to all the must-see spots with ease. Cozy and welcoming, it’s the perfect home base for your holiday in Sicily! ☀️ Sunny balcony for relaxing moments en plein air 🚲 FREE bicycles available throughout your entire stay 🚗 Hassle-free street parking – and it’s free 24/7! We also have two more apartments in the same building—check out my profile to discover them and read our glowing 5-star reviews!

Villa Alex | Private Pool - Fontane Bianche
Villa Alex with a private swimming pool, just 350 meters from the beautiful beach of Fontane Bianche, in a peaceful and quiet area. The villa features a bright living room with TV, sofa, fan, dining table and chairs, a kitchen with a microwave, 3 air-conditioned bedrooms (2 double bedrooms and 1 twin bedroom), and 2 bathrooms, one of which is en suite with both a bathtub and a shower. The perfect choice for families and groups looking to relax and enjoy the sea just a short walk away.

Sea-View Loft. Stylish, Spacious and Comfortable
Experience the magic of Ortigia in this elegant, thoughtfully designed 80m² apartment that blends charm, comfort, and relaxation. Ideal for couples or small groups, it is located just steps from the island’s most iconic sights. Enjoy a stunning sea view balcony, a bright living area complete with a sofa bed, a fully equipped kitchen, a cozy bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, and heating. For your convenience, the building is served by an elevator.

Casa Coco•Palma•Sea View apt. - from 2 to 4 guests
Welcome to Casa Coco Palma, a stylish two-bedroom apartment with breathtaking sea view. IMPORTANT: IF BOOKED FOR 2 PEOPLE THE SECOND BEDROOM WILL BE CLOSED. This is Sicilian coastal living at its pinnacle: your front-row seat to the Ionian Sea, where the salty breezes blend with the gentle sound of waves. Work in a serene dedicated space. Then unwind on your private balcony for morning espresso while watching Ortigia island, or a local glass of wine as sailboats drift by.

Light and Relaxation: Large Open Space on the Garden
Located in a private wing of the villa with a separate entrance, this 95-square-meter open space combines refinement and modernity. The large windows flood the rooms with natural light, while the decor naturally defines the different areas. A perfect balance between design, comfort and nature: the spaces blend harmoniously with the garden, creating relaxation and privacy. For safety and comfort reasons, the property only accommodates children aged 10 and over.

Agàpe Ortigia
Agàpe Ortigia is an accommodation created with Love in the magical island of Ortigia, in the historic center, a stone's throw from the Duomo and the major sites of interest. The independent room is large and spacious, has a double bed, TV, free Wi-Fi, tea and coffee corner, but the peculiarity of this accommodation apart from the furnishings is the bathroom which, in addition to having the main amenities, offers a large sunken tub where you can relax.

Casa Salgiò
Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.

Comfortable apartment with reserved parking space
Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.
Popular amenities for Santa Panagia vacation rentals
Other great vacation rentals in Santa Panagia

Spacious flat close to the sea! + Patio & parking

Elegant apartment in the heart of Syracuse.

Casa Sirokos

Villa with pool + stunning views

Timeless: Detached villa with infinity pool

The Latomia Villa near the Greek Theatre

Allisola Country Villa - Ulivo house

Maison Dumah | Elegant home in Via Maestranza
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- Fontane Bianche Beach
- Calamosche Beach
- Etna Park
- Castello Ursino
- Etnaland
- Piano Provenzana
- Teatro Massimo Bellini
- Fondachello Village
- Castello di Donnafugata
- Castello Maniace
- Greek Theatre of Syracuse
- Villa Bellini
- Oasi Del Gelsomineto
- Sampieri Beach
- Isola delle Correnti
- Fishmarket
- Nature reserve of Vendicari
- Museo Emilio Greco
- Museo Archeologico Regionale Paolo Orsi
- Spiaggia Vendicari
- Temple of Apollo
- Necropolis of Pantalica
- Aci Trezza
- Noto Cathedral





