
Vacation rentals in Santa Panagia
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Top-rated vacation rentals in Santa Panagia
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Penthouse Lady Packard
Lady Packard’s Penthouse is a stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the Cathedral at the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.

Brand new apartment with patio across Ortigia
Fully renovated modern apartment in proximity of Ortigia (6 mins walk) with free parking. With its three ensuite double bedrooms, the apartment can accommodate up to 6 people. All the rooms have aircon and 32' smart TV as same as the living room equipped with a 50' smart TV, a cozy couch and a few armchairs. A fully equipped kitchen and a patio to enjoy a glass of wine around a wooden table with your family and friends. Never wait around as you can check yourself in with the access code!

Victor' apartment
Victor apartment è un accogliente appartamento luminoso, rifinito con cura ed eleganza nel cuore della città nuova a pochi passi dai servizi. Ha un ampio soggiorno con cucina separata e divano letto due posti. Spaziosa camera da letto matrimoniale con armadio. Il bagno è comodissimo con doccia. L'appartamento offre wi-fi gratuito, climatizzatore, tv e lavatrice e posto auto gratuito adiacente al giardino interno di proprietà.Divertiti con tutta la famiglia in questo elegante alloggio.

Sea-View Loft. Stylish, Spacious and Comfortable
Experience the magic of Ortigia in this elegant, thoughtfully designed 80m² apartment that blends charm, comfort, and relaxation. Ideal for couples or small groups, it is located just steps from the island’s most iconic sights. Enjoy a stunning sea view balcony, a bright living area complete with a sofa bed, a fully equipped kitchen, a cozy bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, and heating. For your convenience, the building is served by an elevator.

Ortigia, Boutique Apartment, Balconies
Nel cuore del centro storico, Ortigia, nel suggestivo quartiere Graziella, questo elegante appartamento offre un’esperienza autentica e raffinata. Al primo piano di una piccola palazzina storica, l’appartamento è luminoso, silenzioso e pensato per una coppia in cerca di atmosfera, relax e bellezza. I balconi sulla piazza, sono perfetti per colazioni lente e aperitivi al tramonto. Un rifugio romantico nel cuore di Ortigia, a pochi passi dal mercato, dal Duomo e dal mare.

Elegant Ortigia View Suite
La Suite is located in the center of Syracuse, on the 7th floor of an elegant building. 500 meters away is Syracuse station, 900 meters from the historic center Ortigia, a 15-minute walk to the Cathedral and 900 meters from the Neapolis Archaeological Park. The area is served by bars, supermarkets, bakery, bank, pharmacy and private parking for a fee. The suite has a kitchen, washing machine, en-suite bathtub, private bathroom with shower, hairdryer, and toiletries.

Casa dei Leoni – Balcony overlooking Piazza Duomo | Ortigia
Wake up overlooking Piazza Duomo in the heart of Ortigia. Casa dei Leoni, a real home in the very heart of Ortigia. Overlooking Piazza Minerva, just a few steps from the Cathedral, this elegant apartment blends the charm of Sicilian history with modern comfort. Bright interiors, a private balcony with an open view, and carefully curated spaces make Casa dei Leoni the ideal place for guests seeking beauty, peace, and an authentic stay in Syracuse’s historic center.

Light and Relaxation: Large Open Space on the Garden
Located in a private wing of the villa with a separate entrance, this 95-square-meter open space combines refinement and modernity. The large windows flood the rooms with natural light, while the decor naturally defines the different areas. A perfect balance between design, comfort and nature: the spaces blend harmoniously with the garden, creating relaxation and privacy. For safety and comfort reasons, the property only accommodates children aged 10 and over.

La Terrazza
The apartment, recently renovated, is located on the third floor near the Porta Marina. The location is optimal for those wishing to visit the beauties of this land, including Piazza Duomo, Forte Aretusa, Piazza Archimede and take long walks enjoying the exceptional view of the sea of the Marina. It is also possible to reach wonderful seaside areas by choosing between a relaxing day at the beach or in one of the many solariums on the Ortigia seafront.

Casa Salgiò
Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.

Sky Rooftop Ortigia
In the vibrant heart of Ortigia, just a few steps from the touristic port, this charming home welcomes you in a truly unbeatable location. Here, you can immerse yourself in the authentic atmosphere of the historic center, surrounded by picturesque alleys, local shops, and traditional restaurants, with the sea always within sight. The apartment is located on the third floor and is accessible by stairs only.

Comfortable apartment with reserved parking space
Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.
Popular amenities for Santa Panagia vacation rentals
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Sea view
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- Fontane Bianche Beach
- Etna Park
- Etnaland
- Calamosche Beach
- Castello Ursino
- Piano Provenzana
- Teatro Massimo Bellini
- Castello Maniace
- Fondachello Village
- Castello di Donnafugata
- Greek Theatre of Syracuse
- Villa Bellini
- Sampieri Beach
- Isola delle Correnti
- Museo Emilio Greco
- Oasi Del Gelsomineto
- Fishmarket
- Nature reserve of Vendicari
- Temple of Apollo
- Spiaggia Vendicari
- Museo Archeologico Regionale Paolo Orsi
- Necropolis of Pantalica
- Noto Cathedral
- Palazzo Biscari





