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Vacation rentals in Santa Fe

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Popular amenities for Santa Fe vacation rentals

Other great vacation rentals in Santa Fe

Private room in Calobre
4.64 out of 5 average rating, 11 reviews

Hostal Brisas Calobreñas, A home to stay in Panama

BernadetteRating, 5 stars4 months ago
the bedroom in the back allows you to be quiet in privacy, installed on the small terrace in front. the bathroom is attached to the bedroom and used only by its occupants. Everything is very simple but clean. Kitchen equipment is basic but enough for us to cook. We are far from luxury, but in relation to the price, and the place is nice. the owners who live on site are welcoming and have always responded to our requests by trying to satisfy them. The wifi goes well. The weak point for us is the lack of storage.
Private room in Santa Fe
4.88 out of 5 average rating, 104 reviews

BLUE FROG Santa Fe Home with a View

NanaeRating, 5 stars2 months ago
Mike’s place is a heaven on earth ! No noise except the sound of the running river down below, beautiful surroundings, spacious house. A private swimming hole of the beautiful clean river Santa Maria in his property is the cherry on the top of the cake! Mike is very quiet but friendly host and his dog Jack was so cute! We loved our stay! Highly recommended !
Private room in Santa Fe
4.56 out of 5 average rating, 39 reviews

Award winning Inn with National Park Tours

DaveRating, 5 stars1 month ago
The Coffee Mountain Inn is a beautiful place. We were a bit disappointed there was no mini fridge in our room as it would really have been helpful. The staff and owners were helpful and nice. We would definitely stay here again.
Private room in Rio Hato
5 out of 5 average rating, 3 reviews

Costa Blanca Golf & Beach Villa

BillRating, 5 stars82 months ago
Excelent place and hospitality, we already want to return, Thanks a lot for everything, will recommend it to my close friends
Cabin in Santa Fe
4.7 out of 5 average rating, 47 reviews

Treehouse

YvonneRating, 5 stars1 month ago
Elise was very friendly, she explained everything to us. She place was very nice, especially the view of the water😍☀️.. there are two dogs who are a little shy but are very peaceful;) Pura Vita
Guest favorite
Home in Santa Fe
4.93 out of 5 average rating, 27 reviews

Santa Fe House with an amazing view

JorgeRating, 5 stars2 months ago
We had a very nice stay in Santa Fe! The house was comfortable, well-equipped, and had everything we needed for a relaxing visit. Nestled in nature, it offers an incredible view—you can even see and hear the river from the house. One of the highlights was the direct access to the river, where we spent a full day swimming and unwinding in the peaceful surroundings. Keep in mind that being in nature also means sharing space with a few lizards, ants, and bugs—but that’s all part of the experience. Santa Fe itself is a lovely little town, full of charm and surrounded by stunning natural beauty. There are plenty of nature walks, waterfalls, and adventures to enjoy nearby. Communication was smooth throughout, and even though we arrived a bit late, accessing the house was easy and straightforward. Overall, a great stay!
Hotel room in PA

Vida Lotus Jungle King Room with Hot Tub, Desk

Private room in PA

Hostal De Gracia, live close to nature.

Quick stats about vacation rentals in Santa Fe

  • Total rentals

    30 properties

  • Nightly prices starting at

    G$4,184 GYD before taxes and fees

  • Total number of reviews

    730 reviews

  • Family-friendly rentals

    10 properties are a good fit for families

  • Pet-friendly rentals

    10 properties allow pets

  • Wifi availability

    10 properties include access to wifi

Frequently Asked Questions

  • Are there pet-friendly vacation rentals in Santa Fe?

    Four-legged friends are welcome in Santa Fe. Choose from more than 10 vacation rentals for guests traveling with pets.

  • How much does it cost to stay in house rentals in Santa Fe?

    Experience the best of Santa Fe with our house rentals, starting at about $20 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

Destinations to explore

  1. Airbnb
  2. Panama
  3. Veraguas Province
  4. Santa Fe District
  5. Santa Fe