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Vacation rentals in Santa Fe

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Fe

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Apartment in Santa Fe
4.67 out of 5 average rating, 3 reviews

LaQhia Casa Loros 5

This Panamanium adventure begins nestled in the greenery of a lush rainforest near SantaFe National Park.Your private apartment secluded from the world offers warm air&the scent of greenery&orchids.Sounds of the jungle/tropical birds call daily. LaQhia Eco Retreat has Cayucos Bar/Restaurant.Also a mind body yoga shala offers otehr services.** fees apply Deeper into the rainforest discover hidden cascading waterfalls.Soak in the beauty&relax with nature. *Refer to house manual for more amenities.

The entrance of the cabin is framed by a well-maintained garden featuring various plants. A stone pathway leads to the front door, flanked by trees and lush greenery, creating a serene and natural ambiance. The cabin's roof is adorned with bright tiles, complementing the exterior.
Cabin in Santa Fe
4.71 out of 5 average rating, 7 reviews

Cabañas San Agustin Santa fe Veraguas

2 Cabañas, la primera $ 130.00 esta cuenta con su patio privado y una hermosa vista. La otra cuesta $95.00 Rodeados de naturaleza, podrás relajarte, clima agradable, no necesitas a/c, para compartir con tu familia o amistades, disfrutar alejados del ruido de la ciudad. Internet Wifi en el Rancho común. 2 Recamaras , 1 BAÑO PRIVADO, comedor, COCINA PRIVADA con estufa, refrigeradora, utensilios básicos de cocina. A solo 2. 5km del centro de Santa fe. PRECIOS PUEDEN VARIAR SEGÚN TEMPORADAS

A modern cabin is set within a serene forest of towering pine trees. The structure features a light-colored exterior with a red metal roof and a combination of stone and textured walls. Natural light filters through the windows, enhancing the peaceful atmosphere.
Cabin in Calobre
4.6 out of 5 average rating, 15 reviews

La Pinea Lodge

Disfruta de una agradable y acogedora estadía en la Cabaña entre los Pinos. ideal para quienes buscan tranquilidad, comodidad y pasar una estadía amena con familiares y amigos. Ubicada en la entrada del parque Natural de La Yeguada, en un amplio terreno cerca de atracciones Naturales como el Lago el Flor, Cascada la Furunera y a 3 km de la Laguna. cuenta con comodidades básicas; ademas de ducha con agua caliente, buena señal de teléfono mobil Tigo, amplio lugar para estacionamiento.

A modern cabin with a unique architectural design is showcased, featuring an orange and stone exterior. A covered porch area provides shelter and views of the surrounding greenery. A gray vehicle is parked in front, illustrating easy access to this welcoming space.
Cabin in Santa Fe
4.65 out of 5 average rating, 17 reviews

Cabaña Rincón de Cielo

Disfruta de la naturaleza y una experiencia con estilo en este alojamiento ubicado en el centro de Santa Fe y cerca de Rios, Cascadas y montañas. La propiedad tiene hermosas vistas a las montañas y a un pequeño lago. La propiedad puede alojar más de dos huéspedes previa coordinación y por un precio adicional por persona. La cabaña es elegante y cuanta con una habitación con A/C , lavandería, cosina y sala/comedor. El uso de la cocina y la lavandería tiene un costo adicional de $10.00

Cabin in Santa Fe
New place to stay

Casa Vianka, las mejores vistas a la montaña

¡Bienvenidos a Casa Vianka en Santa Fe, Veraguas! Una espaciosa cabaña ideal para familias o amigos que buscan desconectar en la naturaleza con total comodidad. ¿Por qué elegirnos? • Espacio: 2 amplias habitaciones y 2.5 baños. • Ubicación: Cerca del centro, restaurantes y tiendas. • Aventura: A minutos de los mejores ríos y senderos. Disfruta del clima fresco en este alojamiento tranquilo y céntrico. ¡Reserva hoy y vive Santa Fe!

A spacious white house is set against a backdrop of lush greenery. The building features large windows and is surrounded by various trees. A gently sloping grassy area leads up to the house, providing an open and serene environment.
Vacation home in Santa Fe
4.55 out of 5 average rating, 29 reviews

Lugar encantador para disfrutar en familia o amigo

Disfruta de una amplia casa exclusivamente para ti, tu familia o grupo de amigos. Un lugar donde tendrás entera privacidad y total tranquilidad y donde no tendrás que compartir las instalaciones con otros huéspedes. Hostal Vernaza es una casa segura y tranquila, con acceso a todo (supermercado, farmacia, centro de salud,iglesia,restaurantes,mercado de artesanías, ríos, senderos, cascadas, montaña, playa y demás).

Guest favorite
Farm stay in Santa Fe
4.9 out of 5 average rating, 324 reviews

Cabaña del Sol en Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Guest favorite
Cottage in Santa Fe
4.9 out of 5 average rating, 20 reviews

k* Casa Matilde | 2BR Santa Fe Retreat by River

Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Guest favorite
A rural house with a terracotta roof is situated among lush greenery, framed by mountains. A vehicle is parked in front, with a natural landscape extending around the property. Whispering trees and distant hills offer a serene background.
Cottage in Santa Fe
4.92 out of 5 average rating, 13 reviews

Casa de campo, La Mismísima

La Mismísima es un lugar mágico para desconectarte y vivir una experiencia única en medio de la naturaleza. Un lugar espacioso que te invita a meditar, a leer, a tomarte un buen café con un clima delicioso y especial para los amantes de la fotografía. Es una casa de campo con las comodidades para sentirte en tu casa, con la tranquilidad y la paz que te brinda la naturaleza.

Home in Santa Fe
4.8 out of 5 average rating, 5 reviews

Orange Corner Cottage

Welcome to our centrally located, newly renovated home within the village of Santa Fe. Easy walking distance to the bus terminal, restaurants, cafes, grocery stores and artisanal markets. Enjoy a hot shower, Starlink Wi-Fi and the easy access, central location. Santa Fe now has a new asphalt road from Santiago as well as a fuel station and various ATMs.

Cabin in Calobre
4.75 out of 5 average rating, 28 reviews

La Yeguada - Forest Point Cabin

Lleva a toda la familia a este fantástico lugar con muchas zonas para divertirse, totalmente equipada cabaña de campo con cocina amplia, sala de estar con acceso a televisión, hamacas, refrigerador, estufa, agua caliente y todo lo que necesitas para pasar un buen momento alejado del ruido y convivir con la naturaleza.

Top guest favorite
A spacious living area is surrounded by large windows, offering panoramic views of the lush landscape. Comfortable seating is arranged in a circular layout, adorned with colorful cushions. A central coffee table is complemented by decorative plants and a warm wooden floor enhances the inviting ambiance.
Farm stay in Santa Fe
5 out of 5 average rating, 23 reviews

Mansion en Granja Orgánica Piscina Climatizada

Capacidad 32 personas - Relájate con toda la familia y amigos en esta acogedora casa en una granja organica con animales, sembradios, pesca de tilapia, café, rios, contamos con piscina climatizada, terraza techada de 120 mts para que celebres tus ocasiones especiales.

Popular amenities for Santa Fe vacation rentals

Frequently Asked Questions

  • What are the best places to stay in Santa Fe?

    Staying near the central plaza gives easy access to markets and restaurants, while accommodations just outside town often have quieter surroundings and views of the hills. Some eco-lodges blend sustainably into the rainforest environment.

  • What are the best things to do in Santa Fe with kids?

    Families can explore local waterfalls, visit the central plaza, or join guided hikes in Santa Fe National Park. Many visitors enjoy spotting birds and butterflies throughout the region.

  • What are some of the best things to do in Santa Fe?

    Explore the trails of Santa Fe National Park, wander the local market for fresh produce, and visit nearby waterfalls. Guided tours and nature walks are frequently suggested for learning about the region’s ecology.

  • How is the weather in Santa Fe?

    Santa Fe’s mountain setting brings cooler air than much of Panama, with warm daytime temperatures and refreshing evenings. Rainfall is common, so weather can change quickly; packing layers is often suggested.

  • When is the best time to visit Santa Fe?

    The dry season is often recommended for exploring trails and enjoying clearer mountain views, while the wet season brings lush landscapes and vibrant greenery. Festivals occur throughout the year, each providing a distinct atmosphere.

  • What are the best places to visit in Santa Fe?

    Santa Fe National Park is frequently suggested for nature lovers, while the central plaza draws those seeking local culture. Nearby waterfalls and scenic viewpoints round out popular spots to explore.

  • What are some hiking trails in Santa Fe?

    Hikers often explore trails in Santa Fe National Park and around Cerro Tute, with routes through tropical forests and hillside viewpoints. Paths vary in difficulty, so both gentle walks and steep climbs are available.

  • What are some family activities we can do in Santa Fe?

    Families frequently enjoy hiking easy trails, spotting wildlife, and visiting swimming holes or waterfalls around Santa Fe. Exploring local markets or participating in artisan workshops can also engage younger travelers.

  • What are some of the best day trip ideas from Santa Fe?

    You can explore coffee farms, visit riverside villages, or discover additional hiking trails in the surrounding mountains. Birdwatching excursions and nature-focused tours are also popular options nearby.

  • Are there any pet friendly accommodations available in Santa Fe?

    Some rentals and guesthouses in Santa Fe welcome pets, particularly those situated near hiking areas or outside the central plaza. It is best to check individual property policies before booking.

  • What are some local tips for visiting Santa Fe?

    Greet locals with a friendly buenos días, and consider visiting the town market early for the freshest produce. Comfortable walking shoes and flexibility with plans help make the most of changing mountain weather.

  • What is Santa Fe known for?

    Santa Fe is known for its lush cloud forests, scenic mountain views, and biodiversity. The area frequently draws nature lovers interested in hiking, birdwatching, and tranquil river spots.

  • What are the best hidden gems to explore in Santa Fe?

    Seek out lesser-known waterfalls, small artisan workshops, or riverside picnic spots around Santa Fe. Some visitors enjoy exploring community coffee farms for a glimpse into local traditions.

  • What are the best foods to try in Santa Fe?

    Santa Fe has traditional Panamanian dishes like sancocho, locally sourced grilled meats, and fresh river fish. You may also find homemade cheeses and sweets reflecting regional flavors.

  • What should I bring for a trip to Santa Fe?

    Pack light layers, a rain jacket, sturdy footwear for hiking, and sun protection for changing weather conditions. Insect repellent and a reusable water bottle are also frequently suggested.

  • What is the nightlife in Santa Fe like?

    Nightlife in Santa Fe tends to be low-key, with casual local bars and occasional live music. Evenings often center around gathering spots where visitors and residents unwind and share stories.

  • What are the most popular events or festivals in Santa Fe?

    Santa Fe hosts agricultural fairs and cultural celebrations, featuring local music, crafts, and traditional foods. These festivals often highlight the area's agricultural heritage and attract residents from around the region.

  • Are there family friendly vacation rentals in Santa Fe?

    Santa Fe has family friendly vacation rentals in the town center and quieter residential areas. Many hosts provide spaces with multiple bedrooms, outdoor areas, and self-catering kitchens.

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