
Vacation rentals in Santa Cruz
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Top-rated vacation rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
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Popular amenities for Santa Cruz vacation rentals
Other great vacation rentals in Santa Cruz
Guest favorite

Condo in Nueva Gorgona
4.94 out of 5 average rating, 49 reviewsBahia Beachfront, 3 BR, Flexible Cancellation
Top guest favorite

Condo in Coronado
5 out of 5 average rating, 10 reviewsCoronado bay on the beach with large terrace
Superhost

Home in Las Lajas
4.82 out of 5 average rating, 17 reviewsPerfect Getaway Mountain like House with pool
Guest favorite

Home in El Valle de Antón
4.87 out of 5 average rating, 31 reviewsPrivate Mountain Escape El Valle
Superhost

Villa in Chame District
5 out of 5 average rating, 4 reviewsBeach house with a pool and a hot tub
Guest favorite

Apartment in Nueva Gorgona
4.89 out of 5 average rating, 47 reviewsBeachfront apartment on the 15th floor
Guest favorite

Cabin in Provincia de Panamá Oeste
4.89 out of 5 average rating, 36 reviewsCabin surrounded by mountains with spectacular views
Guest favorite

Cabin in Altos del Maria
4.85 out of 5 average rating, 26 reviewsCabin in Altos del María: La Guarida del Oso
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