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Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A small, rustic structure is positioned amidst a lush, mountainous landscape. A winding gravel road leads towards the building, surrounded by greenery, hills, and trees. The scene is softly illuminated by sunlight, highlighting the natural setting and open space.
Shipping container in San Carlos
4.98 out of 5 average rating, 48 reviews

Justinatinyhouse disconnects to connect

Justinatinyhouse is nestled in the foothills of the San Carlos Lagoon. It has everything you need for your stay with a lot of peace, a cool breeze in the mornings and afternoons, incredible views towards Altos del María, Sorá, Punta Chame, and a dirt road in good condition for any car. It has A/C and everything you need for your stay. It does not have a TV, but there is excellent cell phone coverage. I recommend bringing all the things you need for your food. The nearest store is a 10-minute drive away

Top guest favorite
An aerial view showcases a serene saltwater pool framed by lush greenery. Red umbrellas provide shade for outdoor seating areas. The open kitchen and dining space are visible, along with comfortable hammocks situated nearby, offering a relaxed atmosphere for guests.
Home in Costa Esmeralda
4.98 out of 5 average rating, 192 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Top guest favorite
A modern single-story house is displayed with a large front porch and a carport. The exterior features a mix of light and dark materials, with a neatly landscaped yard and a white picket fence. Clear blue skies and scattered clouds complete the setting.
Home in Chame District
5 out of 5 average rating, 35 reviews

Summer House

Take the whole family to this fantastic place with many areas to have fun. Close to all the amenities of Coronado, a few minutes from beaches, San Carlos lagoon and just an hour and a half from the city. The PH has a PH pool and a private one, in a quiet and spacious area. You will find 4 supermarkets, pharmacies, and a private hospital (emergency room). Close to country activities, beaches, mountains, lake. It has a gazebo with all the amenities. The place is safe and complete.

Top guest favorite
A stone paved area features four wooden chairs arranged around a central fire pit, illuminated by soft landscape lighting. In the background, a cabin structure can be seen, bordered by lush greenery and softly lit paths, creating an inviting outdoor space.
Cabin in Provincia de Panamá Oeste
4.89 out of 5 average rating, 272 reviews

Buenavista Cabin by Casa Amaya

Casa Amaya is a cabin complex located one hour from the capital city, in Chicá de Chame, with pleasant temperatures between 18 and 24 degrees, where you can get in touch with nature and relax with your partner, friends or family. Other cabins: https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya We have an electric generator in case of outages.

Guest favorite
Large sliding glass doors open to reveal a view of the serene garden and swimming pool, complemented by lush greenery. A cozy corner with a comfortable sofa and decorative plants adds to the relaxed indoor ambiance.
Villa in Panamá
4.87 out of 5 average rating, 151 reviews

Nice house with pool steps to the beach

Relax with the whole family in our Rincon de Flavio, a quiet place to stay for the weekend or as long as you need. Three bedrooms with two bathrooms. Fully equipped and decorated in a tropical style. WE NOW HAVE AIR CONDITIONING IN ALL THE ROOMS. With everything you need to enjoy and relax. A 5-minute walk to Coronado Beach and close to restaurants and supermarkets. Large garden, ping pong, swimming pool and comfortable patio with barbecue.

Guest favorite
An outdoor patio space is presented with wooden chairs and a small table. Lush green grass extends towards the sandy beach, adorned with palm trees and sun loungers under thatched umbrellas, creating a calm coastal view.
Home in Chame
4.81 out of 5 average rating, 86 reviews

P/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath

This unique place has a style all its own, steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views and great on-site amenities. 1km of beach to offer you the best beach and surfing experience around.

Guest favorite
A large swimming pool is surrounded by tropical palm trees, appearing inviting under a clear blue sky. Lounge chairs are positioned around the pool area, providing ample space for relaxation. A portion of the pool is shallow, leading toward a landscaped section with greenery.
Apartment in San José
4.85 out of 5 average rating, 149 reviews

B31-Tropical beach paradise, 2R/2B condo, w/pool

Disconnect for a few days from the routine. Have fun with your partner or family in our apartment in Punta Barco Viejo, we have everything you need to be comfortable and have fun in one of the most exclusive areas of the area. We have everything nearby for your best convenience, restaurants, banks, supermarkets ... I´ll deliver a personalized 5 stars attention. Oh and of course, the BEACH 5min by car!

Top guest favorite
A bright living area features a comfortable sofa and a glass coffee table topped with a decorative plant. Bar stools are positioned at a kitchen counter, and a dining table accommodates seating. Large windows allow natural light to enhance the open space.
Condo in Nueva Gorgona
4.97 out of 5 average rating, 148 reviews

Spectacular Beach Apt-PH Royal Palm-Gorgona

FIRST LINE TO THE SEA WITH DIRECT ACCESS TO THE BEACH FROM THE PH POOLS. Spectacular apartment overlooking the ocean and Chame Hill, fully furnished for your family to enjoy. The PH has two social areas with 4 swimming pools, a sauna, a gym, a children's play area, a barbecue area, and 3 multipurpose courts. The PB social area has direct access to the sea. UP TO ONE (1) PET IS ACCEPTED.

Guest favorite
The earth-sheltered studio home is nestled among lush greenery, with large windows offering views of the surrounding nature. The circular design blends with the landscape, demonstrating a harmonious relationship with its natural environment.
Tiny home in Altos del Maria
4.82 out of 5 average rating, 167 reviews

Arcón House

This earth-sheltered studio home offers a unique and romantic escape in the mountain of Altos del Maria. Cozy space surrounded by a lush green environment, ideal for those seeking a peaceful getaway, or an affordable stay to explore the gated community's amenities. This bunker home provides an inviting haven to unwind and disconnect from the hustle of city life.

Guest favorite
A panoramic view of the serene coastline is depicted, showcasing several islands in the distance surrounded by calm waters. Luscious green hills lead towards the shore, providing a tranquil backdrop under a subtly overcast sky.
Guest suite in Panamá Oeste
4.83 out of 5 average rating, 103 reviews

Casa Buena Vista

The house is newly built within walking distance to the lookout in the Altos De Campana National Park only 45 minutes from Panama City. With absolutely stunning views it sleeps 4 to make your stay a relaxing, tranquil experience. Bring your own cooler, cook for yourself in a full complete kitchen if you like and enjoy your drinks by the pool.

Guest favorite
A scenic view of a beach with gentle waves lapping at the shore, flanked by lush greenery. Palm trees sway in the breeze, offering shade to thatched-roof cabanas and a pool area. The backdrop features various buildings along the coastline, creating a picturesque setting.
Condo in Nueva Gorgona
4.9 out of 5 average rating, 135 reviews

Fantastic Beach condo with Beach & mountain views.

Relax with the whole family at this peaceful place to stay. It has a kids area to play, weight room area, sauna, soccer and tennis courts. 2 adult pools and 2 kiddie pools and a Jacuzzi. There is a grill area to rent out and a restaurant on site. This condo has great views of the mountains and the beach.

Top guest favorite
A spacious bed is dressed in a colorful quilt, complementing an inviting orange pillow. Large glass doors offer a panoramic view of the surrounding mountains and lead to a private outdoor space with a swimming pool.
Tiny home in Panamá
4.98 out of 5 average rating, 216 reviews

Mountain cabin in Altos del María

The cabin in Altos del María is located in the heart of the mountain, with beautiful landscapes, trees, animals, monkeys, birds, just minutes from picnic areas, outdoor games, river, waterfall, trails and viewpoints. Escape into nature! Close to everything, away from the daily grind!

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz