Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

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Top guest favorite

A modern single-story house is displayed with a large front porch and a carport. The exterior features a mix of light and dark materials, with a neatly landscaped yard and a white picket fence. Clear blue skies and scattered clouds complete the setting.

Home in Chame

5 out of 5 average rating, 21 reviews

Casa de Veraneo

Lleva a toda la familia a este fantástico lugar con muchas zonas para divertirse. Cerca a todas las amenidades de Coronado, a pocos minutos de playas, laguna de San Carlos y a tan solo una hora y media de la ciudad. El PH cuenta con piscina del PH y una privada, en una zona tranquila y espaciosa. Encontraras 4 supermercados, farmacias, hospital privado (urgencias). Cerca a actividades campestres, playas, montañas, lago. Tiene en un gazebo con todas las comodidades. El lugar es seguro y completo.

Top guest favorite

Loft in Chame

5 out of 5 average rating, 14 reviews

Secteur Chica 2 Grands Lofts, vue mer et Autodromo

🩷 DEUX Grands lofts indépendants. (2 personnes par loft) Les 2 lofts sont complètement indépendant Chaque unité : WiFi - Air climatisé - Frigo 1 chambre 🛏️ (lit orthopédique) 1 salon 🛋️ 1 salle de bain 🚿 Stationnements Gardien 24h sur place 👮‍♀️ Terrasse privée VIP juste pour VOUS Coin cuisine & Four à pizza au feu de bois 🍙 Profitez d'une vue incroyable sur la vallée, la mer, les îles de Punta Chame et le nouvel AUTODROMO 🏁 25 km de Coronado 28 km de Costa Verde 50 km de Panama

Superhost

A bright bedroom features a spacious bed layered with soft linens and a cozy throw blanket. Decorative wall art complements the modern design. A bedside lamp adds a warm touch, while large windows offer scenic views of the ocean and natural light filling the room.

Apartment in Nueva Gorgona

4.89 out of 5 average rating, 101 reviews

Cozy Beachfront Apartment

This small and cozy apartment is the perfect place to call home. Located just steps away from the beach with its charming and homey atmosphere. The large windows allow natural light to flood the space. It has everything you need in a compact and convenient space. The living room is warm and inviting. The kitchen is fully equipped with modern appliances, making it easy to prepare meals at home. The bedroom is spacious and bright, with a comfortable bed and plenty of storage for your belongings.

Guest favorite

An expansive view of a tranquil beach is seen, with soft sandy shores meeting clear turquoise waters. The horizon features a blend of blue sky and distant buildings, while palm trees and shaded cabanas dot the beach area.

Condo in Chame

4.96 out of 5 average rating, 165 reviews

Exclusive Beachfront apartment 1Hour from Pma City

ESPECTACULAR apartamento de lujo FULL EQUIPADO con 3 recamaras (todas con vista directa al mar), 2 baños completos y medio baño de visita; cuarto y baño de servicio. Finos acabados, cocina 100% de acero inoxidable y aires acondicionados en todo el apartamento de alta eficiencia. Condominio con concepto "Hotel Style Living"; Restaurante y Bar para las noches (de Jueves a Domingo), snack bar en el area de la piscina y un Tiki Bar en la playa, ademas de cancha de Volleyball , Tenis, basketball.

Top guest favorite

An aerial view of the property showcases a spacious layout surrounded by lush greenery. A large saltwater pool and a hot tub are visible alongside a well-maintained outdoor area with red umbrellas providing shade. The roof of the main structure features a brown tone, blending with the natural surroundings.

Home in Costa Esmeralda

4.98 out of 5 average rating, 178 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with solar and battery backup systems.

Guest favorite

A stone paved area features four wooden chairs arranged around a central fire pit, illuminated by soft landscape lighting. In the background, a cabin structure can be seen, bordered by lush greenery and softly lit paths, creating an inviting outdoor space.

Cabin in Provincia de Panamá Oeste

4.87 out of 5 average rating, 246 reviews

Cabaña Buenavista by Casa Amaya

Casa Amaya es un complejo de cabañas ubicado a una hora de la ciudad capital, en Chicá de Chame, con temperaturas agradables entre 18 y 24 grados, donde podrás contactarte con la naturaleza y relajarte con tu pareja, amigos o familia. Otras cabañas: https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya Contamos con generador eléctrico en caso de apagón.

Top guest favorite

The exterior of the house features a charming design with a red-roofed upper level and a welcoming terrace. A small pool is visible in the foreground, surrounded by lush greenery and natural rock formations. Cloudy skies create a serene atmosphere, enhancing the tranquil setting.

Home in El Nancito

4.94 out of 5 average rating, 18 reviews

Mountain Retreat: Peaceful & Private Escape

Escape to tranquility in our beautiful rural retreat near Laguna de San Carlos, Panama. Nestled on a private hectare of lush land, this cozy two-bedroom, two-bath house boasts an open terrace with breathtaking views of the San Carlos mountains. Whether basking in summer sun or enveloped in clouds during the rainy season, you’ll find peace and beauty here. Just a 30-minute drive to Coronado and the stunning beaches of Panama Oeste, it’s the perfect sanctuary for your getaway.

Guest favorite

A small wooden deck features two chairs and a table, positioned against a maroon wooden exterior. Natural surroundings are visible in the background, with trees enhancing the outdoor space's appeal. A subtle decorative sign hangs near the window.

Cabin in El Valle de Antón

4.86 out of 5 average rating, 121 reviews

A 5 min del Valle I Cabaña Increíble Vista 2

Esta cabaña es moderna y llena de Naturaleza. La cabaña está a 5 minutos antes de llegar al Valle de Antón, tiene un solo espacio donde están las camas, cocina y desayunador. Afuera hay una terracita con una linda vista para disfrutar. Tiene TV con HBOMax, cafetera y estufa eléctrica sin horno. Los últimos 3 minutos del camino hay una calle de piedra, pero un Picanto pasa sin problemas. Se permiten hasta dos perros pequeños. Check in 3 pm y Check out 12 md.

Superhost

A living area features a spacious couch and a round coffee table with a potted plant. Large glass doors open to a balcony, offering unobstructed ocean views. A wall-mounted television is visible, alongside textured curtains and a decorative area rug on the tiled floor.

Apartment in Nueva Gorgona- Panamá Oeste

4.78 out of 5 average rating, 352 reviews

Lovely Beach Apart. seafront*Royal Palm*P.Gorgona

Private beach apartment, on high floor, with ocean view, two bedrooms, one bathroom, high quality appliances, remote lighting control on any mobile devices, A/C in bedrooms and living room. Netflix and Amazon Prime services on televisions. Tennis courts, basketball, soccer, gym, barbecue area and playground, two floors of social area, swimming pool for exercise and recreation for adults & children's pool) direct access to the beach.

Guest favorite

An inviting infinity pool is positioned on a spacious patio, overlooking a sweeping mountain view. Two lounge chairs are arranged on the deck, facing the water, while lush greenery and colorful blooms enhance the serene environment surrounding the pool area.

Cottage in Altos del Maria

4.94 out of 5 average rating, 163 reviews

Mountain Cottage with Heated Pool and Amazing View

Mountain Cottage, with spectacular views of the Altos del María Mountains, perfect for relaxing or spending time with the family. It features a heated infinity pool, spacious outdoor spaces, Smart TV and A/C in all rooms and living room, Wi-Fi throughout the property, and is fully equipped. Includes Prime Video service. It also has a fire pit and a gas BBQ. Complimentary late checkout is available for rentals departing on Sundays.

Superhost

Condo in Nueva Gorgona

5 out of 5 average rating, 3 reviews

Gorgeous Beachfront High Floor

Oceanfront escape! Bright 2BR/2BA condo with floor-to-ceiling windows, modern kitchen, and private balcony overlooking the turquoise sea. Relax in the spacious living area, enjoy stunning sunsets, or unwind in the stylish bedrooms with en-suite baths. Perfect for couples, families, or remote work with breathtaking views. Steps from the beach, dining & entertainment. Your dream coastal getaway awaits!

Top guest favorite

Home in Nueva Gorgona

5 out of 5 average rating, 16 reviews

Spectacular Beachfront House

Beautiful house with private beach access right on the property. Relax on the hammocks and be surrounded by nature, with the best ocean view. Only 10 minutes drive from Coronado with all its amenities. There are two wonderful caretakers on the property who are in charge of security, cleaning, and can answer questions and help you with anything you need.