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Vacation rentals in Santa Cruz

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Loft in Campana
4.9 out of 5 average rating, 10 reviews

Superbe Loft A, avec vue mer, vallée et Autodromo

🩷 Profiter d'un espace social, gym, piscine en 🩷, jacuzzi semi-privée, terrasse couverte. Quoi de mieux pour venir se détendre en couple dans ce logement calme et élégant. Ce logement offre aussi une terrasse privée à partir de votre chambre. Vous êtes en famille, nous avons un autre loft que vous pouvez louer ou même la maison complète avec 4 chambres pouvant accueillir jusqu'à 8 personnes (autre annonce). ** L'espace extérieur (cuisine/bbq) est partagé avec d'éventuels autres voyageurs.

Superhost
Apartment in Nueva Gorgona
5 out of 5 average rating, 3 reviews

Sky-High: Ocean & Mountain Views

Escape to this bright, modern 1 bdrm, one-bath condo on the 19th floor of Royal Palm, a sought-after beachfront project. Enjoy panoramic ocean and mountain views. Open-concept dining and living area, ideal for both dining and working. The space is fully equipped, light-filled, and thoughtfully designed for relaxation. Step onto the private balcony and savor the tropical breeze or unwind by the building's pools. Perfect for beach lovers seeking a high-floor retreat with all the comforts of home.

Top guest favorite
Home in Chame District
4.96 out of 5 average rating, 47 reviews

Casa de Veraneo

Lleva a toda la familia a este fantástico lugar con muchas zonas para divertirse. Cerca a todas las amenidades de Coronado, a pocos minutos de playas, laguna de San Carlos y a tan solo una hora y media de la ciudad. El PH cuenta con piscina del PH y una privada, en una zona tranquila y espaciosa. Encontraras 4 supermercados, farmacias, hospital privado (urgencias). Cerca a actividades campestres, playas, montañas, lago. Tiene en un gazebo con todas las comodidades. El lugar es seguro y completo.

Top guest favorite
An aerial view showcases a serene saltwater pool framed by lush greenery. Red umbrellas provide shade for outdoor seating areas. The open kitchen and dining space are visible, along with comfortable hammocks situated nearby, offering a relaxed atmosphere for guests.
Home in Costa Esmeralda
4.98 out of 5 average rating, 203 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Guest favorite
A large outdoor pool features a seamless design with a shallow area lined by smooth stone steps. Palm trees surround the pool, extending towards the sandy beach in the distance, where sun loungers and umbrellas are arranged. The sky is bright and partly cloudy.
Condo in Bejuco
4.91 out of 5 average rating, 46 reviews

Beachfront Bliss in Playa Caracol (5H)

Make some memories at this unique and family-friendly place. Fully furnished 2 bed/2 bath 5th floor apartment with a large balcony with view of the main pool social area and coastline with dining & kitchen space allows 4 guests plus a child. Bring the whole family to this great place with lots of room for fun. Unique 5th floor apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views. With 1km of beach to offer you the best beach experience around.

Guest favorite
An aerial view reveals a stretch of coastline featuring sandy beaches with a mix of dark volcanic sand and vibrant turquoise water. Lush greenery lines the shore, complemented by residential areas visible in the background, creating a serene and inviting landscape.
Tiny home in San Carlos
4.81 out of 5 average rating, 129 reviews

Cozy beach cabin at Costa Esmeralda.

Cozy private community cabin on a triple space for up to three people located in Costa Esmeralda beach, over the Pacific ocean. Very quiet area with a 2,200 Square meter patio with trees and vegetation. Relax enjoying of the tropical sun, warm temperatures all year long and the ocean breeze. Only 9 minutes away by walk from the closest beach with warm waters and volcanic black sand. 10 minute drive to Coronado (Grocery Stores, restaurants, bakeries, movie theater, malls and much more)...

Top guest favorite
Cabin in Provincia de Panamá Oeste
4.89 out of 5 average rating, 285 reviews

Cabaña Buenavista by Casa Amaya

Casa Amaya es un complejo de cabañas ubicado a una hora de la ciudad capital, en Chicá de Chame, con temperaturas agradables entre 18 y 24 grados, donde podrás contactarte con la naturaleza y relajarte con tu pareja, amigos o familia. Otras cabañas: https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya Contamos con generador eléctrico en caso de apagón.

Top guest favorite
Apartment in Nueva Gorgona
4.94 out of 5 average rating, 50 reviews

Amazing 2 bedroom Apartment

Welcome to Royal Palm 1501 beachfront apartment. You couldn't get any closer to the Beach than the Royal Palm location. In this comfortable 2 bedroom 1 bathroom apartment you will find all you need to feel at home. Pots, Pans, Silverware, Linens etc. The Royal Palm offers a wide variety of amenities including indoor parking a gym, 4 pools, a beautiful sauna and whirle pool. whether your looking to explore panama or just want to enjoy the amenities and ocean at your doorstep

Top guest favorite
Apartment in Las Lajas
5 out of 5 average rating, 9 reviews

Stylish & New, a short stroll away from the Beach

Welcome to your beachside escape at the Bambu Beach Haus! This brand-new modern duplex features a spacious king bed, stylish design, and all the comforts of home. Enjoy cooking in the fully equipped kitchen, relax on your private terrace or balcony, and take in the laid-back coastal vibe. Located in a resort-style community just a short stroll from the beach, you’ll also have access to a sparkling saltwater pool, jacuzzi, and cozy bohios—perfect for a relaxing getaway.

Top guest favorite
Apartment in Chame, Panama
5 out of 5 average rating, 8 reviews

24 horas vista al Mar en Coronado

Relájate en este espacio tan tranquilo y elegante. Puedes caminar y llegar a la playa , caminas y puedes ir a comer rica cena o almuerzo con restaurantes muy cercanos, si deseas ir al gym tenemos todos los implementos, ir y disfrutar de la piscina , encantadora y grande para nadar, tenemos mesas de pipon,mesa de billar ,un área de recreación, y tienes espacio de trabajo, y vista refrescante al mar. contamos una habitación con cama Queen y un sofá cama .

Guest favorite
A bright living area features a comfortable sofa and a glass coffee table topped with a decorative plant. Bar stools are positioned at a kitchen counter, and a dining table accommodates seating. Large windows allow natural light to enhance the open space.
Condo in Nueva Gorgona
4.97 out of 5 average rating, 152 reviews

Espectacular Apto de Playa-PH Royal Palm-Gorgona

PRIMERA LINEA AL MAR CON BAJADA DIRECTA A LA PLAYA DESDE LAS PISCINAS DEL PH. Espectacular apartamento con vista al mar y cerro Chame, completamente amoblado para ser disfrutado por su familia. El PH tiene dos areas sociales con 4 piscinas, sauna, gimnasio, area de juegos para niños, area de barbacoa y 3 canchas multiusos. Del area social de PB se accede directamente al mar. SE ACEPTAN HASTA UNA (1) MASCOTA.

Top guest favorite
An aerial view of a serene property shows a large swimming pool surrounded by palm trees. Lounge chairs are positioned along the poolside, offering ample space for relaxation. The casitas and greenery in the background create a welcoming outdoor atmosphere.
Guesthouse in Nueva Gorgona
4.99 out of 5 average rating, 76 reviews

Beautiful Casita-Paradise in Panama, Nueva Gorgona

Fully furnished beautiful one bedroom casita is 500 sq. feet with an open living/dining concept. Fully equipped kitchen with new appliances and granite countertops. King size bed in bedroom and offers plenty of storage. Hide-a-bed in living room sleeps 2. **A great property for groups as we have two casitas and two studios on the property. Rent all four and have the place to yourself!

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz