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Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A modern single-story house is displayed with a large front porch and a carport. The exterior features a mix of light and dark materials, with a neatly landscaped yard and a white picket fence. Clear blue skies and scattered clouds complete the setting.
Home in Chame District
5 out of 5 average rating, 28 reviews

Casa de Veraneo

Lleva a toda la familia a este fantástico lugar con muchas zonas para divertirse. Cerca a todas las amenidades de Coronado, a pocos minutos de playas, laguna de San Carlos y a tan solo una hora y media de la ciudad. El PH cuenta con piscina del PH y una privada, en una zona tranquila y espaciosa. Encontraras 4 supermercados, farmacias, hospital privado (urgencias). Cerca a actividades campestres, playas, montañas, lago. Tiene en un gazebo con todas las comodidades. El lugar es seguro y completo.

Top guest favorite
An aerial view of the property showcases a spacious layout surrounded by lush greenery. A large saltwater pool and a hot tub are visible alongside a well-maintained outdoor area with red umbrellas providing shade. The roof of the main structure features a brown tone, blending with the natural surroundings.
Home in Costa Esmeralda
4.98 out of 5 average rating, 184 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Superhost
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guesthouse in Panamá Oeste
4.81 out of 5 average rating, 105 reviews

Casa de Montaña en Panamá

Disfruta de la paz y la naturaleza en esta acogedora y equipada cabaña, perfecta para desconectar y relajarte. Rodeado de bosques y con vistas espectaculares, aquí podrás respirar aire puro y contemplar las estrellas. ✔️ Ideal para parejas, familias o aventureros. ✔️ Senderos, ríos y miradores cercanos. ✔️ Espacios cómodos y equipados para tu confort. - Capacidad de 4 personas. - Posibilidad de tener 1 cama doble y 2 individuales o 4 camas individuales. - Descuento a partir de dos noches.

Top guest favorite
A stone paved area features four wooden chairs arranged around a central fire pit, illuminated by soft landscape lighting. In the background, a cabin structure can be seen, bordered by lush greenery and softly lit paths, creating an inviting outdoor space.
Cabin in Provincia de Panamá Oeste
4.88 out of 5 average rating, 263 reviews

Cabaña Buenavista by Casa Amaya

Casa Amaya es un complejo de cabañas ubicado a una hora de la ciudad capital, en Chicá de Chame, con temperaturas agradables entre 18 y 24 grados, donde podrás contactarte con la naturaleza y relajarte con tu pareja, amigos o familia. Otras cabañas: https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya Contamos con generador eléctrico en caso de apagón.

Guest favorite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del Maria
4.81 out of 5 average rating, 299 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Top guest favorite
A covered patio area displays a mix of seating options, including two wicker chairs and a small glass-top table surrounded by greenery. A hammock hangs gracefully in the foreground, adding a touch of comfort to this relaxed outdoor setting.
Cottage in El Valle de Antón
4.99 out of 5 average rating, 144 reviews

Casa Campestre Los Macos, El Valle de Antón

🏡 Bienvenidos a Casa Campestre Los Macos, un refugio acogedor ubicado en el corazón verde de El Valle de Antón, dentro de un cráter volcánico extinto, el más grande habitado en el mundo. Es una experiencia de descanso total, en una zona segura y tranquila, ideal para amantes de la naturaleza, el silencio y el aire puro. Despertarás con el canto de los pájaros, disfrutarás una taza de café en el jardín y pasarás tardes familiares en una casa totalmente equipada.

Guest favorite
An outdoor patio space is presented with wooden chairs and a small table. Lush green grass extends towards the sandy beach, adorned with palm trees and sun loungers under thatched umbrellas, creating a calm coastal view.
Home in Chame
4.8 out of 5 average rating, 82 reviews

P/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath

This unique place has a style all its own, steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views and great on-site amenities. 1km of beach to offer you the best beach and surfing experience around.

Guest favorite
A large swimming pool is surrounded by tropical palm trees, appearing inviting under a clear blue sky. Lounge chairs are positioned around the pool area, providing ample space for relaxation. A portion of the pool is shallow, leading toward a landscaped section with greenery.
Apartment in San José
4.85 out of 5 average rating, 143 reviews

B31-Tropical beach paradise, 2R/2B condo, w/pool

Disconnect for a few days from the routine. Have fun with your partner or family in our apartment in Punta Barco Viejo, we have everything you need to be comfortable and have fun in one of the most exclusive areas of the area. We have everything nearby for your best convenience, restaurants, banks, supermarkets ... I´ll deliver a personalized 5 stars attention. Oh and of course, the BEACH 5min by car!

Guest favorite
A wooden deck extends from the entrance, featuring two chairs positioned to enjoy the outdoor environment. The entrance leads into a well-lit interior space, framed by lush greenery that enhances the tranquil setting.
Cabin in El Valle de Antón
4.86 out of 5 average rating, 103 reviews

A 5 min del Valle I Cabaña Increíble Vista 1

Esta preciosa cabaña está a 5 minutos antes de llegar al Valle de Antón, tiene un solo espacio donde están las camas, cocina y desayunador. Afuera hay una terracita. tiene TV con HBOMax, cafetera y estufa eléctrica sin horno. Los últimos 3 minutos del camino es calle de piedra, pero un Picanto pasa sin problemas. Se permiten hasta 2 perros pequeños. Check in 3 pm y Check out 12 md.

Top guest favorite
Home in Nueva Gorgona
5 out of 5 average rating, 17 reviews

Spectacular Beachfront House

Beautiful house with private beach access right on the property. Relax on the hammocks and be surrounded by nature, with the best ocean view. Only 10 minutes drive from Coronado with all its amenities. There are two wonderful caretakers on the property who are in charge of security, cleaning, and can answer questions and help you with anything you need.

Guest favorite
A panoramic view of the serene coastline is depicted, showcasing several islands in the distance surrounded by calm waters. Luscious green hills lead towards the shore, providing a tranquil backdrop under a subtly overcast sky.
Guest suite in Panamá Oeste
4.83 out of 5 average rating, 103 reviews

Casa Buena Vista

The house is newly built within walking distance to the lookout in the Altos De Campana National Park only 45 minutes from Panama City. With absolutely stunning views it sleeps 4 to make your stay a relaxing, tranquil experience. Bring your own cooler, cook for yourself in a full complete kitchen if you like and enjoy your drinks by the pool.

Top guest favorite
A spacious living area features large windows that provide a view of the ocean. Comfortable seating options include a sectional sofa and armchairs. A round coffee table sits on a textured rug, while ceiling fans circulate air in the bright, airy space.
Condo in Nueva Gorgona
4.94 out of 5 average rating, 193 reviews

Fabuloso Apto de playa-Ph Royal Palm-Gorgona

PRIMERA LINEA AL MAR CON BAJADA DIRECTA A LA PLAYA DESDE LAS PISCINAS DEL PH . Fabuloso APTO DE PLAYA, Beach Front Unit, cómodo, único y para relajarte en Familia, cuenta con 4 increíbles piscinas, jacuzzi, sauna, canchas deportivas, juegos de mesa y acceso a la playa y servicio de Restaurante, venir es no querer irte nunca

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz