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Hotel vacation rentals in Santa Cruz

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Top-rated hotel rentals in Santa Cruz

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Superhost
A spacious hotel room is featured, showcasing a seating area with a circular dining table and a sofa. Large windows allow natural light to enter, providing views of the surrounding area. The sleeping area includes a large bed and a wall-mounted flat-screen TV.
Hotel room in Santa Cruz de la Sierra
4.6 out of 5 average rating, 30 reviews

"Feel at Home"Breakfast buffet !

The room is in the heart of the financial and business district of Santa Cruz ,just a few minutes walk from the main square of the city .Guest will find many shops , supermarket and restaurants nearby and places to go out at night ,only 5 minutes walk from accommodation . Featuring free wifi ,free parking,air conditioning , private bathroom ,cable , american breakfast free of charge ! Guest can relax by the pool , the jacuzzi or make use of the sauna .Fitness facilities are also available!

The spacious living area features a round dining table surrounded by four elegant chairs. A chandelier hangs overhead, illuminating the space. A comfortable sofa is positioned along a wall with a large window that provides natural light and access to a balcony.
Hotel room in Santa Cruz de la Sierra
4.75 out of 5 average rating, 68 reviews

Luxurious 5 Star Hotel Suite in Equipetrol area

Located in the best neighborhood in the city, Barrio Equipetrol. You'll be staying in a 118m2 Suite at a 5-Star hotel where you can enjoy the safety and comfort of a top-rated hotel. Work trip? With a co-work space and blocks away from the Business Area of the city. Coming to explore Santa Cruz? Only steps away of San Martin Avenue to visit the most trendy restaurants, shopping malls and social experiences in Santa Cruz. Also located only 10 minutes away from the historical center of the city

Guest favorite
A spacious room features a large bed with neatly arranged white linens and towels. An intricate wall tapestry adds a cultural touch. Sunlight enters through a round window and arched glass doors, while a small table and two chairs are positioned nearby.
Hotel room in Samaipata
5 out of 5 average rating, 14 reviews

Yvy Casa Hotel / Room Alegria

INCLUDES BREAKFAST Room Arte, at YVY CASA HOTEL, is the perfect refuge for those seeking peace and connection with nature. Surrounded by lush trees and the whisper of the wind, this place offers a serene relaxing atmosphere. Each morning, enjoy a delicious artisanal breakfast prepared with fresh regional ingredients. The perfect combination of comfort and tranquility awaits you in this natural heaven. Ideal for disconnecting and revitalizing the body and mind.

Superhost
A bright and spacious room features a red bedspread on a large bed, complemented by two bedside lamps. A window provides garden views, while a small seating area with wrought-iron chairs and an orange cushion is visible. A television is mounted on the wall.
Hotel room in San José de Chiquitos
4.71 out of 5 average rating, 7 reviews

Classic double room at La Villa Chiquitana Hotel

Classic category double room. It is located on the ground floor, with a view of the main garden and access from the internal patio. This is the Ametauná room, decorated with Chiquitano motifs; the cheapest with all the services and amenities. - Air-conditioning -TV -WIFI -Refrigerator -Hygiene products -Daily cleaning -Breakfast included Villa Chiquitana is a spacious environment of relaxation and comfort to experience the essence of Chiquitania.

A modern living area is depicted, featuring a sleek black sofa bed facing a glass dining table with two chairs. Light beige walls complement the clean tile flooring. Natural light enters through large windows, and framed photographs are displayed on the wall.
Hotel room in Santa Cruz de la Sierra
4.8 out of 5 average rating, 5 reviews

Furnished apartment for executives in Equipetrol

40mts apartment, 1 bedroom, 1 bathroom, living /dining room, and kitchen. 1 flat screen TV, cable TV with 100 channels, air conditioning heat/cold in all environments, digital safe, 2 wifi signals with fiber optic. It has an excellent location (100 meters from the Tajibos Hotel Convention Center, 200 meters from the Business Center and 400 meters from the Ventura Mall). In addition to a team for your attention 24 hours a day, during your visit.

Top guest favorite
Private room in Santa Cruz de la Sierra
5 out of 5 average rating, 23 reviews

Quiet and close to everything.

Enjoy this cozy, quiet and central accommodation, where you can rest comfortably, as well as being a perfect starting point to explore the city since we are just a few minutes from the center, we also have shared spaces within the house, such as a kitchen where you can prepare your food and we will also include a delicious welcome breakfast from the second day of your stay so that you can enjoy it as it should be!

Guest favorite
Private room in Valle Sánchez
4.86 out of 5 average rating, 69 reviews

A few minutes from the airport.

After an exhausting trip, nothing better than resting in a quiet and peaceful place while waiting for your next destination. If you are an animal and plant lover, you will feel especially loved, accompanied by nature and our pets if you wish. As the hammock sways, you can read a good book, listen to music, or enjoy a delicious grilled meat with vegetables and have some delicious juices with seasonal fruits.

An outdoor seating area is presented under a covered patio, featuring a stone accent wall and comfortable sofas arranged around a low coffee table. Vibrant pink bougainvillea plants add a touch of color, while the grassy area offers a peaceful setting.
Casa particular in Santa Cruz de la Sierra
4.81 out of 5 average rating, 21 reviews

Very comfortable house with 3 bedrooms

Very comfortable house with three spacious bedrooms and 2 full baths, kitchenette, dining room, shared pools, shared pools, shared churrasqueras, green trails, large gardens, Polo courts, tennis, soccer and basketball and a beautiful natural lagoon. has free parking, WiFi, TV. Located 20 minutes from downtown very close to Viru Viru Airport

Guest favorite
A light-filled room features a spacious bed with soft bedding and a side table adorned with a vase of fresh flowers. Large glass doors open to a garden, enhancing the connection to nature, while neutral walls and wooden flooring provide a calming setting.
Private room in Santa Cruz de la Sierra
4.82 out of 5 average rating, 17 reviews

Your oasis of comfort (La Galería)

Just 5 minutes from Viru Viru Airport, ideal for travelers looking for a quick, safe, pleasant and hassle-free stay. Enjoy an automated room with voice-activated lights and curtains and a relaxing garden view.

Superhost
A cozy room is shown with a spacious bed dressed in a light quilt and a burgundy accent. A small round table and two chairs are placed near a window that provides a view of the outdoor greenery. A wooden dresser and a television complete the layout.
Hotel room in Santa Cruz de la Sierra
4.5 out of 5 average rating, 4 reviews

Room with breakfast, comfortable and centrally located

Comfortable room with a private bathroom and breakfast included. It's in an excellent location. Close to the Foianini Clinic and Cainco. It also has free parking on the premises.

Superhost
Private room in Santa Cruz de la Sierra

Independent Apartment

This unique home has plenty of space for you to enjoy with your own. Apartment with separate entrance and parking. With work areas and easy access to all points in the city.

Guest favorite
An expansive rooftop pool is illuminated by soft lighting, creating a serene ambiance at dusk. Lounge chairs are arranged along the water's edge, inviting relaxation. The pool's reflective surface mirrors the evening sky, with a modern building visible in the background.
Hotel room in Colinas del Urubó
4.84 out of 5 average rating, 19 reviews

Comfortable Suite at Hotel Radisson

Suite con cama “KING BED O TWIN “ Baño moderno Cable tv y WIFI Acceso a suana y jacuzzi Acceso a terraza y piscina Desayuno incluido Aire acondicionado Ladera Ropero

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