Apartment vacation rentals in Santa Cruz Department

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Top-rated apartment rentals in Santa Cruz Department

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Guest favorite

Apartment in Centro

4.95 out of 5 average rating, 22 reviews

"Centrally located apartment. Independent, Spacious and Safe"

You will be close to everything if you stay in this independent apartment; spacious and centrally located, 1/2 block from the market 7 streets, minutes from Plaza Principal 24 de Sept. (Pharmacy, Bars, Restaurants, Shoppings, Banks and more), an atmosphere like at home. Ideal place for sightseeing and getting to know the best of Santa Cruz, safe area, 1st floor, building fronts. It has wifi 24 hrs., Netflix, washing machine, balcony overlooking downtown, kitchen, washing machine, patio, living room dining room.

May 24 – 31

G$3,579 GYD per night

Guest favorite

Apartment in Santa Cruz de la Sierra

4.97 out of 5 average rating, 31 reviews

Luxurious stay at modern apartment (Equipetrol)

Astounding apartment furnished to an impeccable standard. It’s the ideal retreat for an exquisite & up-scale stay, located close to the absolute heart of Santa Cruz in one of its finest neighbourhoods. We believe it’s the ultimate location to experience Santa Cruz the way it should be. Get ready to get inspired! Very close to some fabulous sites. All in all, guaranteed enjoyment and relaxation. All day long. Settle in by zoning out with a small company in a professionally cleaned home.

Aug 11 – 18

G$9,544 GYD per night

Guest favorite

Apartment in Santa Cruz de la Sierra

5.0 out of 5 average rating, 26 reviews

Luxury Apartment - Stunning Pool - Sky Lumiere 1BR

Discover the luxury lifestyle at Sky Lumiere! This stunning apartment offers breathtaking views of Santa Cruz. Experience modern living with all the latest amenities, including a fully equipped kitchen, air conditioning, high-speed internet, and more comfy features. Step outside and find an array of dining, shopping, and entertainment options just a few steps away in the business district of Santa Cruz "Equipetrol".

May 25 – Jun 1

G$9,132 GYD per night

Guest favorite

Apartment in Santa Cruz de la Sierra

4.96 out of 5 average rating, 47 reviews

Luxurious I am a student in Equipetrol Norte

Elegant and comfortable, brand new, one-bedroom apartment. Located in the heart of Equipetrol Norte, steps from the business area and just a few blocks from the Ventura Mall, close to supermarkets, shops and the best restaurants in Santa Cruz. The apartment is fully equipped, ideal for tourists or business travelers who want to have an unbeatable stay in the best area of Santa Cruz.

Jun 9 – 16

G$5,138 GYD per night

Superhost

Apartment in Centro

4.8 out of 5 average rating, 20 reviews

Apartment. Central Spacious in front of Parque Urbano 2 Dorm.

Beautiful 2 bedroom apartment (one en suite), 2 bathroom, with all amenities, central and quiet. Located between 1 and 2 ring in front of the Urban Park, which is an open space of beautiful vegetation ideal for walking. It is close to the Blacut Plazuela, Estadio y Cine Center. The condominium has a pool, parking for one vehicle and 24/7 security.

Nov 29 – Dec 6

G$7,317 GYD per night

Guest favorite

Apartment in Santa Cruz de la Sierra

4.94 out of 5 average rating, 81 reviews

Exclusive apartment on the best area of SC

Hermoso y cómodo departamento ubicado en la zona más exclusiva y segura de Santa Cruz, a pocos minutos de los principales centros comerciales, supermercados, restaurantes y de fácil acceso a cualquier parte de la ciudad. El departamento cuenta con las comodidades necesarias para que tengas una grata estadía ya sea por viajes de negocio y/o turismo.

May 12 – 19

G$7,430 GYD per night

Superhost

Apartment in Santa Cruz de la Sierra

4.79 out of 5 average rating, 166 reviews

Equipetrol Exclusive Zone, Cozy Monoambiente

Beautiful studio apartment located in Equipetrol, one of the most exclusive areas of the city. It has WiFi, smart TV with Netfflix and other amenities. It's ventilated and bright. The building has a pool and 24/7 doorman service.... be welcome!! Learn more about its features when clicking on "Show more"

Jan 17 – 24

G$4,688 GYD per night

Guest favorite

Apartment in Santa Cruz de la Sierra

4.9 out of 5 average rating, 81 reviews

Luxurious Studio. Equipetrol Norte

Comfortable and elegant one-room apartment. Located in the heart of Equipetrol Norte, steps from the business area and just a few blocks from the Ventura Mall. Fully equipped. It is ideal for tourist or business travelers who want to have an unbeatable stay in the best area of Santa Cruz.

Sep 21 – 28

G$4,931 GYD per night

Superhost

Apartment in Santa Cruz de la Sierra

4.94 out of 5 average rating, 31 reviews

LumiArt: Apartamento artistico de lujo

''LumiArt'' is unique and has its own style. The apartment is brand new, fully equipped and spacious. It is located near consulates, pharmacies, restaurants and has the business center with block 40 blocks away. Open for families, executives and anyone who wants to have an amazing stay!

Oct 3 – 10

G$12,511 GYD per night

Guest favorite

Apartment in Santa Cruz de la Sierra

4.86 out of 5 average rating, 22 reviews

Downtown StunningTerrace Apartment

This special place is close to everything, making it easy to plan your visit. Close to many cultural and downtown attractions such as museums, coffe shops, cathedrals and many more. The apartment is very tranquil, easy to access, comfortable and with an amazing terrace.

Jun 29 – Jul 6

G$13,684 GYD per night

Superhost

Apartment in Santa Cruz de la Sierra

4.8 out of 5 average rating, 10 reviews

Excellent location with a breathtaking view.

Can you imagine waking up and enjoying your breakfast on the 8th floor balcony? The view of Santa Cruz de la Sierra is really impressive. Ideal for starting the day with the best vibes. If you dare… Our goal will be to give you the best hosting experience.

Aug 17 – 24

G$7,439 GYD per night

Superhost

Apartment in Santa Cruz de la Sierra

4.89 out of 5 average rating, 27 reviews

Studio YOU by INN

Práctico, innovador y eco friendly, edificio YOU by Smart Studio se ubica en Equipetrol Norte a pocos metros del cuarto anillo. YOU cuenta con 2 torres de Smart studios , una de apartamentos, uno de parqueos y uno de áreas comunes.

Aug 25 – Sep 1

G$10,260 GYD per night