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Vacation rentals in Santa Clara

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Top-rated vacation rentals in Santa Clara

Guests agree: these stays are highly rated for location, cleanliness, and more.

Superhost

Home in Gamboa

4.87 out of 5 average rating, 84 reviews

BirdHouse@ Gamboa Panamá Canal

Explore the wonders of the Panama rainforest and return to our magical tropical home! This unique house and pool is a wonderful place to escape the hustle of Panama City, celebrate nature, and enjoy family and friends. Gamboa is a safe, quiet town embedded in the Soberania National Park; it is the entry point to Pipeline Road, some of the best birding in the world. Or take leave of the forest and watch manatee, while fishing for peacock bass in Gatun Lake or paddling kayaks up the Chagres River.

Jan 14 – 21

G$76,463 GYD per night
Guest favorite

Condo in Chame

4.96 out of 5 average rating, 135 reviews

Exclusive Beachfront apartment 1Hour from Pma City

ESPECTACULAR apartamento de lujo FULL EQUIPADO con 3 recamaras (todas con vista directa al mar), 2 baños completos y medio baño de visita; cuarto y baño de servicio. Finos acabados, cocina 100% de acero inoxidable y aires acondicionados en todo el apartamento de alta eficiencia. Condominio con concepto "Hotel Style Living"; Restaurante y Bar para las noches (de Jueves a Domingo), snack bar en el area de la piscina y un Tiki Bar en la playa, ademas de cancha de Volleyball , Tenis, basketball.

May 16 – 23

G$31,629 GYD per night
Guest favorite

Guesthouse in Gamboa

4.95 out of 5 average rating, 56 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Jul 31 – Aug 7

G$18,202 GYD per night

Popular amenities for Santa Clara vacation rentals

Other great vacation rentals in Santa Clara

Guest favorite

Chalet in Veracruz

4.89 out of 5 average rating, 89 reviews

A beachfront property very near to Panama city

Jun 13 – 20

G$13,646 GYD per night
Guest favorite

Cottage in Sorá

4.93 out of 5 average rating, 90 reviews

Luxury Private Cottage in Altos del Maria

May 15 – 22

G$20,352 GYD per night
Guest favorite

Home in San Carlos

4.93 out of 5 average rating, 85 reviews

Beach House-Ocean View Rooftop Jacuzzi & Pool

Sep 6 – 13

G$54,481 GYD per night
Guest favorite

Cottage in Altos del Maria

4.93 out of 5 average rating, 92 reviews

Cabin with Spectacular Mountain View

Jun 17 – 24

G$67,872 GYD per night
Guest favorite

Home in Río Hato

4.95 out of 5 average rating, 74 reviews

Spectacular beachfront house in Buenaventura!

Aug 24 – 31

G$144,562 GYD per night
Guest favorite

Villa in Río Hato

5.0 out of 5 average rating, 38 reviews

Luxury 4BR Villa + Guesthouse & Pool @Buenaventura

Apr 20 – 27

G$94,488 GYD per night
Guest favorite

Villa in Bejuco

4.96 out of 5 average rating, 78 reviews

Beach house in Punta Chame, Villa frente al mar

Aug 2 – 9

G$146,351 GYD per night
Superhost

Vacation home in Arraiján

4.8 out of 5 average rating, 44 reviews

Apartment In Club De Playa, with Pool and BBQ

Oct 26 – Nov 2

G$15,373 GYD per night
Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 53 reviews

Cozy n Comfy con balcón in the heart of Casco

Nov 11 – 18

G$23,951 GYD per night
Guest favorite

Cottage in Panamá

4.94 out of 5 average rating, 17 reviews

Modern House in Altos de Cerro Azul with 2 rooms

Jun 4 – 11

G$28,587 GYD per night
Guest favorite

Cabin in Panamá

4.97 out of 5 average rating, 37 reviews

The Crystal House: Luxury Modern Wood Cabin

Apr 10 – 17

G$88,530 GYD per night
Guest favorite

Cabin in Chicá

4.95 out of 5 average rating, 44 reviews

Cabaña Horizonte by Casa Amaya

Sep 4 – 11

G$15,338 GYD per night

Destinations to explore