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Villa vacation rentals in Sanibel Island

Find and book unique villas on Airbnb

Top-rated villa rentals in Sanibel Island

Guests agree: these villas are highly rated for location, cleanliness, and more.

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Top guest favorite
A private heated saltwater pool is surrounded by a screened enclosure, featuring vibrant pink flamingo floats floating atop the blue water. Lush greenery and palm trees are visible in the background, with a spacious patio area and outdoor seating nearby.
Villa in Cape Coral
4.96 out of 5 average rating, 101 reviews

Cape Escape- Private Heated Salt Water Pool

Relax with the whole family at our peaceful place to stay. 🤩Great neighborhood and very private. Centrally located with many near by restaurants and stores. Short ride to Sanibel and Fort Myers Beaches. Many fun activities close by, water park, amusements, mini golf and movie theater. Garage is made into a game room with Ping pong, bumper pool table & bikes. Cornhole is provided to use in backyard. Beautiful private heated saltwater pool, heated to 86* year round. (no child protection screen).

Top guest favorite
An outdoor space features a screened-in pool area with a rectangular swimming pool and a hot tub. Poolside lounge chairs with blue cushions are arranged around a small table. Lush greenery is visible in the background, enhancing the private ambiance.
Villa in Cape Coral
4.95 out of 5 average rating, 124 reviews

LAST Minute! NEW Villa-Heated Saltwater Pool & Spa

Experience Cape Coral like never before all from this gorgeous 3bedroom, 3bath villa. This elegant villa boasts a vibrant interior decorated with Italian furniture and fully equipped kitchen. Begin your day with a few laps in the private pool before heading to the Yacht Club Public Beach, Sun Splash Family Waterpark or Pine Island to soak up some sun! After adventurous days, continue making memories back home with a family barbecue and a soak in the hot tub or have a movie night with loved ones!

Guest favorite
The modern exterior of the home is highlighted by a manicured lawn and tropical landscaping, featuring palm trees and colorful shrubs. A paved driveway leads to a two-car garage, while a covered entrance invites guests into the villa.
Villa in Cape Coral
4.88 out of 5 average rating, 126 reviews

Heated Pool | Canal | Modern | New | Southern Exp.

Welcome to the brand new, absolutely stunning, Villa Southbreeze! This 3 bedroom, 2 bathroom vacation rental is fully furnished &equipped. Stunning high ceilings, huge 72" fireplace, office, laundry room all Samsung stainless-steel appliances, and much more. Out by the huge screened-in pool area you'll find a private electric heated pool, BBQ propane grill, several loungers, large table + chairs. The heated pool features two fountains and a shallow "beach area". Welcome to the villa Southbreeze!

Guest favorite
A serene shared lake area is surrounded by pyramid-shaped homes. Palm trees and colorful lounge chairs are positioned by the water's edge. A gentle fountain is centrally located in the lake, creating a tranquil atmosphere under a partly cloudy sky.
Villa in Fort Myers
4.9 out of 5 average rating, 342 reviews

Private pyramid home to relax and explore-7021

Relax and enjoy the beauty of sunny southwest Florida in your own unique pyramid! This private vacation home in Pyramid Village features a spring water lake just a short walk from your pyramid (this pyramid has nature views, not lakeside) *Home includes: Free WIFI, private patio with gas grill, washer/dryer, fully equipped kitchen, and 2 queen beds (comfy for 4 guests), 2 Roku TV's, and beach gear (located 15 miles from most popular beaches). * self check in with lock box

Top guest favorite
A welcoming living area features a green accent wall with a neon sign. Two hanging chairs provide a cozy seating option. Large sliding doors open to a private pool area, allowing natural light to fill the space.
Villa in Cape Coral
4.98 out of 5 average rating, 128 reviews

Luxury Cape Coral Villa with Private Heated Pool

Escape to your own private pool oasis in sunny Southwest Florida—where swaying palms, crystal-clear water, and warm coastal breezes set the stage for relaxation, family fun, and unforgettable memories. Hassle-Free Stay: NO CHECKOUT DUTIES – just enjoy your stay! IMPORTANT: Please ensure you've read and accept the house rules prior to booking. Thank you. Easy access to Fort Myers (RSW) and Punta Gorda (PGD) Airports – only 24 miles away!

Top guest favorite
An open-concept living area is showcased, featuring a modern sectional sofa and a sleek coffee table. Large glass doors lead to the outdoor space, allowing natural light to fill the room. A contemporary dining area with stylish fixtures is visible in the background.
Villa in Cape Coral
5 out of 5 average rating, 60 reviews

BRAND NEW Luxury Villa w/Heated and Chilled Pool

Brand new high-end 3 bedroom 3 bath designer home, elegantly decorated with incredible views and direct no-bridge Gulf access. Come and make your lifetime memories in this elegantly appointed executive villa. Located near Matlacha, Sanibel, Fort Myers, and Naples. Extra wide canal with only trees opposite, a salt water lagoon, and just off the spreader canal means incredible solitude and privacy in your elegant oasis retreat.

Top guest favorite
Villa in Fort Myers Beach
5 out of 5 average rating, 7 reviews

Luxury Waterfront Home • Pool • Dock • Near Beach

Experience refined coastal living in Siesta Isles, Fort Myers Beach. This 4,000+ sq ft waterfront retreat offers a quick 5-minute drive to the beach and seamless, direct Gulf access by boat. Features include a private dock with lift, heated pool, open-concept design, multiple lounge areas, outdoor kitchen, and a separate TV suite with bar—perfect for families, groups and boaters seeking privacy, comfort, and location.

Guest favorite
The outdoor space features a private heated pool and spa, framed by a wooden privacy fence. Two lounge chairs are positioned beside the water, and a large umbrella provides shade. Tropical palm trees are visible in the background, creating a serene ambiance.
Villa in Cape Coral
4.99 out of 5 average rating, 121 reviews

Waterfront "Casa del Lago" Heated Pool & Jacuzzi

Welcome to your dream vacation home in sunny Florida! This luxurious retreat offers a spacious 4BR/3BA Cape Coral waterfront villa for 8 with a private pool, hot tub, chef’s kitchen, free parking, pet-friendly policy, and reliable Wi‑Fi—perfect for families, couples, business travelers, and remote workers. Casa del Lago is a luxurious waterfront getaway designed for those who seek both relaxation and indulgence.

Top guest favorite
A spacious outdoor area features a heated pool surrounded by a paved deck. Comfortable lounge chairs and an umbrella are positioned nearby, offering a relaxing space. The backyard is framed by greenery and a fenced perimeter, ensuring privacy and a serene ambiance.
Villa in Cape Coral
5 out of 5 average rating, 143 reviews

Casa Capri | Heated Pool | No Service Fee

Escape to Luxury! We've got you covered - no service fees! Discover our 5-star Cape Coral retreat: high-speed WiFi, smart TVs, premium bedding, and more. Unwind in style and serenity. Your peaceful haven awaits! Nestled in the heart of Cape Coral, our meticulously designed space promises an unforgettable stay for the discerning traveler. Relax with the whole family at this peaceful place to stay.

Top guest favorite
A dining area features a long wooden table set for eight, surrounded by sleek black chairs. A sideboard holds decorative items, and large windows provide a view of the outdoors, allowing natural light to enhance the minimalist decor.
Villa in Cape Coral
4.98 out of 5 average rating, 101 reviews

Luxury Canalfront Pool Retreat w/ Upscale Finishes

Beautiful, modern NEW construction home with heated pool, on saltwater canal. Damage-free after hurricane Milton. FUN for families and tranquil for adults; fully stocked with electronic games table, pool toys and floats, outdoor games, arcade games, board games — much to enjoy! Enjoy indoor/outdoor living on expansive resort-style lanai and retreat to stylish finishes & luxe amenities throughout!

Top guest favorite
Villa in Matlacha Isles-Matlacha Shores
5 out of 5 average rating, 7 reviews

Palm Paradise of Matlacha

Fully stocked and beautifully furnished 3 bedroom/ 2 bath waterfront home with heated pool, kayaks, and fishing poles. Located in wonderful and quaint Matlacha Isles - a boater's and fisherman's dream - just minutes away from open water and Florida's most renowned Tarpon fishing spots. Fishing tours and boat rentals available. Sleeps 6 - full pool heat and electricity included in price.

Guest favorite
Villa in Cape Coral
5 out of 5 average rating, 21 reviews

VRCC Villa Mermaid Cove

Mermaid Cove is a tranquil oasis located at the end of a quiet street that ends in a cul-de-sac. Offering captivating water views from every angle, this residence is located within the heart of the Rosegarden. Numerous restaurants and stores nearby along with world class white sand beaches close by like Ft Myers Beach, Sanibel, Naples Beach, Siesta Key and more!

Popular amenities for Sanibel Island villa rentals

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