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Family-friendly vacation rentals in San Luis

Find and book unique family-friendly homes on Airbnb

Quick stats about vacation rentals that are family-friendly in San Luis

  • Total vacation rentals

    Explore 120 vacation rentals in San Luis

  • Verified guest reviews

    Over 3,140 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 40 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    50 properties have a dedicated workspace

  • Wi-Fi availability

    120 of San Luis vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis rentals

  • 4.9 Average rating

    San Luis stays are highly rated by guests—averaging 4.9 out of 5!

Top-rated family-friendly rentals in San Luis

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Yuma
4.95 out of 5 average rating, 110 reviews

Relaxing 2 Bedroom Attached Guest House

Stylish and relaxing attached 2Bedroom Guest house.Quiet neighborhood 5 min away from Onvida Yuma Regional center 4 min from Walmart,Starbucks and fast food restaurants. You will also have access to the shared pool and backyard.Pool is not heated but is available all year.Fully stocked kitchen,stacked washer & dryer in unit for your convenience.This apartment is adjacent to another airbnb property.Complete apartment is 100% private.Access to shared pool and backyard. Max guest occupancy 4 people

Guest favorite
The outdoor area features a private solar heated pool with a unique shape, surrounded by a spacious patio. Comfortable seating areas, including lounge chairs and a dining set, are arranged under a covered patio, complemented by well-maintained landscaping.
Home in Yuma East
4.94 out of 5 average rating, 120 reviews

Private Desert Retreat | Pool, Arcade & RV Parking

Experience elevated comfort in this spacious, serene retreat. Thoughtfully crafted for business and leisure travelers, the home features brand-new Samsung smart appliances, a pool, an arcade game, and a grill/smoker. Enjoy refined indoor comfort, stylish gathering spaces, ample parking for up to 5 vehicles (including RVs and desert vehicles), and step-free entry for wheelchairs, power chairs & walkers. Whether lounging poolside or unwinding indoors, this property offers a truly exceptional stay

Guest favorite
Home in Yuma
4.95 out of 5 average rating, 134 reviews

Yuma’s Best | Pet Friendly | Snowbirds Welcome

Modern desert retreat in the clean, quiet Lynwood neighborhood of Yuma. Open layout with high ceilings and dome skylights that bring in natural light without added desert heat. Ideal for snowbirds, families, traveling professionals, and guests visiting Algodones for dental care (18 mins). Pet-friendly with private backyard patio—perfect for relaxing mornings and evening grilling. High-speed reliable WiFi, Spectrum cable TV + streaming. Close to shopping, golf, dunes, and Los Algodones, MX.

Top guest favorite
The modern exterior of the home features a clean façade with a spacious driveway leading to a two-car garage. A well-maintained lawn and pathway enhance the welcoming appearance. The entrance is highlighted by a covered porch and decorative elements, indicating attention to detail.
Home in Yuma
4.97 out of 5 average rating, 115 reviews

Modern Pet friendly Home, w/backyard/ trlr parking

Welcome to The Stay! Your modern, home-away-from-home. Whether you’re visiting for work or play, you’ll love the comfort, convenience and amenities this home offers. Just 10 minutes from Downtown, or the Foothills, The Stay puts you close to everything. Enjoy a fully landscaped backyard for relaxing evenings, 2-car garage, and gated access for trailers. This home is Pet friendly, So your four-legged family members are welcome too! The Stay is sure to make your time in Yuma comfortable.

Guest favorite
A cozy living area is highlighted by a sofa, decorated with a vibrant green cushion. A small table holds decorative items, and large glass doors open to a private pool area, framed by greenery and natural light.
Apartment in San Luis
4.97 out of 5 average rating, 147 reviews

Heated Pool, 2 Queen beds private apartment Enjoy

The property is divided in to two airbnbs with there own private entrence and private backyard grill outdoor dining and fire pit lounge area. None of the areas are shared they are 100% privateEnjoy your time at this stylish place make great memories at the poolside !! Pool is totally private for this unit in winter season pool temperature can vary depending on the weather outside it’s not a close pool heater is normally on from Nov to May. Enjoy your time in this special place.

Top guest favorite
A spacious bedroom features a comfortable bed dressed in neutral tones with decorative pillows. Two mirrors reflect natural light from a window framed by simple blinds. A textured rug complements the wood flooring, while a dresser and nightstands add functional decor.
Home in Yuma
4.98 out of 5 average rating, 237 reviews

Tuscany Style Casita

Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Guest favorite
A modern single-story home is showcased from the street, featuring a light-colored exterior and a gabled roof. The driveway leads to a three-car garage, with desert landscaping visible, including palm trees and various shrubs. Mountains are faintly visible in the background.
Home in Yuma
4.95 out of 5 average rating, 227 reviews

Beautiful Pool Home in Yuma Foothills!

Enjoy your stay at this modern pool home in Yuma! This property features 2 large master suites, each room has a king bed and sofa bed. Kitchen has high end built in cooktop and ovens, also all brand new appliances. Living room is extra spacious. 3 car garage. This house is near the foothills library, foothills golf courses, the sheriffs station, the I-8. Outside features fire-pit, pool, bbq grill, sitting areas, fruit trees, and more! Great home to kick back and relax.

Guest favorite
Tiny home in Yuma
4.87 out of 5 average rating, 163 reviews

Santa Fe 4 Tiny Studio

Welcome to Casa Santa Fe #4! "This boutique hotel-themed house" offers everything from single to double rooms. Santa Fe #4 is a cosy one-room studio that's fully equipped for a wonderful stay. Our fantastic communal pool area is all set for enjoyment! Just a quick note, if you fancy a dip in the jacuzzi, it does come with an extra fee of $40 USD. We've tailored everything here to provide you with a serene and peaceful stay. We're so excited for your visit!

Guest favorite
A bright and spacious living area features light-colored furniture, including a sofa and dining table. Large windows provide ample natural light, while green cabinetry adds a pop of color. A fully equipped kitchen with modern appliances is visible, creating a welcoming atmosphere for relaxation and gatherings.
Camper/RV in San Luis Río Colorado
4.89 out of 5 average rating, 136 reviews

Alebrije: Full of Life, Nature, and Color

Welcome to this place created especially for you. Enjoy a morning coffee in a space full of nature and tranquility. Our motorhome has all the amenities and you'll enjoy a pleasant rest. You can also enjoy a barbecue with your family while the warmth of the campfire lights up your evening. Alebrije has privacy as it is located on a fenced plot of land exclusively for the motorhome and an excellent neighborhood.

Top guest favorite
A spacious living area is highlighted by a textured ceiling and natural light filtering through large windows. Comfortable seating options include a brown leather sofa and two blue upholstered chairs. A decorative area rug sits beneath a coffee table, and a ceiling fan provides air circulation.
Home in Yuma
4.95 out of 5 average rating, 132 reviews

LUXURY Living 5

You will enjoy your stay at this two-story fully furnished LUXURY rental. It has 4 bedrooms, 2 bathrooms and is located on a quiet residential street. Relax on the large covered patio, next to the pool. Great location in the center of town near shopping, golf courses, and restaurants. You are just a short drive away from Mexico, Colorado River, sand dunes, and hiking.

Guest favorite
Home in Yuma
4.82 out of 5 average rating, 187 reviews

Yuma Cozy Casita

Enjoy our cozy home. Less than a mile away from the Yuma airport. We welcome you to come to enjoy The beautiful weather yuma has to offer in the winter. You will also have a dedicated workspace with a desk. Close to all your shopping needs. Algodones is about 25 minutes, and San Luis Mexico is approx. 45 minutes. Please note that the POOL IS NOT GATED, NOR HEATED.

Top guest favorite
A cozy sleeping area features a spacious bed with soft gray bedding and multiple plush pillows. A decorative wall map is displayed above the headboard, and a bedside lamp provides soft lighting. A small plant and a framed picture add subtle touches to the room.
Apartment in San Luis Río Colorado
4.97 out of 5 average rating, 104 reviews

Comfortable SLRC Apartment

Keep it simple at this peaceful and centrally-located place. Located in the geographic center of San Luis Rio Colorado, very close to the main shops, schools, and workplaces. 10 minutes from the international border crossing. This apartment is attached to a single-family house but has a separate entrance, private bathroom and a parking space in a closed garage.

Popular amenities for San Luis family-friendly rentals

When is the best time to visit San Luis?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$21,127 GYDG$21,545 GYDG$22,382 GYDG$19,453 GYDG$20,081 GYDG$20,918 GYDG$20,708 GYDG$20,708 GYDG$20,081 GYDG$18,826 GYDG$20,290 GYDG$20,918 GYD
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