
House vacation rentals in San Luis
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Top-rated house rentals in San Luis
Guests agree: these houses are highly rated for location, cleanliness, and more.

Meraki Luxury" Home" 5 minutes from the border
This luxury home is designed thinking of our guest experience, cozy and comfortable . You will enjoy the indoor and outdoor areas great for a couples getaway asome for family time and lovely for having the house for yourself. Enjoy yourselves it’s an open layout well designed with unique charm a full kitchen super comfortable couch for movie night. outdoor is the perfect space to have a drink and relax its your home away from home Two private airbnbs with private entrance and private back yards

Cozy Foothills Retreat 3BD/2 Bath/Hot Tub/Cable TV
Perfect for families, couples, winter visitors, and traveling professionals, this home offers the ideal mix of comfort and relaxation. After a day of exploring or working unwind in the private hot tub and enjoy Arizona evenings on the patio. Relax comfortably indoors in reclining sofas in the main living room, big screen TV in the main living room. Play a game of pool or retire to a space all your in your private room or the second living room with a comfortable leather sofa and big screen TV.

Mi Bonita Coquette
This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Private Desert Retreat | Pool, Arcade & RV Parking
Experience elevated comfort in this spacious, serene retreat. Thoughtfully crafted for business and leisure travelers, the home features brand-new Samsung smart appliances, a pool, an arcade game, and a grill/smoker. Enjoy refined indoor comfort, stylish gathering spaces, ample parking for up to 5 vehicles (including RVs and desert vehicles), and step-free entry for wheelchairs, power chairs & walkers. Whether lounging poolside or unwinding indoors, this property offers a truly exceptional stay

Yuma’s Best | Pet Friendly | Snowbirds Welcome
Modern desert retreat in the clean, quiet Lynwood neighborhood of Yuma. Open layout with high ceilings and dome skylights that bring in natural light without added desert heat. Ideal for snowbirds, families, traveling professionals, and guests visiting Algodones for dental care (18 mins). Pet-friendly with private backyard patio—perfect for relaxing mornings and evening grilling. High-speed reliable WiFi, Spectrum cable TV + streaming. Close to shopping, golf, dunes, and Los Algodones, MX.

Bright 4 bedroom home in the heart of town.
This 4 bedroom getaway brings all the comforts of home to your vacation. With the ability to comfortably sleep 10 people there’s plenty of room for you and your friends or family. Enjoy an evening of dinner under the lit gazebo and s’mores around the fire pit or hit the town and check out all the Yuma has to offer. This home is centrally located so you’re never far from food and drinks. Just a 20 minute drive to the dunes, a 15 minute drive to Mexico and a one minute walk down to the park.

San Luis,Arizona- Centrally located-7min to border
Casa Arizona is located in the heart of San luis Az, easy access to everything from this centrally located place. Less than 7 min from the San Luis Rio Colorado border. 25 min from Yuma. Our place is perfect to host comfortably up to 5 people. Washer and Dryer for your convenience. Short and long stays are welcome. Note: You are renting the main house. We also have an studio on the property with its own private entrance and patio. Both spaces are designed for a relaxing experience.

Tuscany Style Casita
Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Welcome To Our Cozy Home! Fully Equipped 3BR/2BA
Welcome to our cozy home! Enjoy this incredible clean and modern home. This home is ready for cooking, sleeping and enjoying the amazing Yuma sunshine. Our nearest shopping center is 2 miles away! We have a Walmart, Albertsons, Taco Bell…The marine base is 4 miles, the border of Algodones is 20 minutes drive. Locate in a safe and family neighborhood. Home is equipped with a fully accessible closet to ensure confort for longer stay.Just 4 miles to downtown Yuma and Hwy 8!

Beautiful Pool Home in Yuma Foothills!
Enjoy your stay at this modern pool home in Yuma! This property features 2 large master suites, each room has a king bed and sofa bed. Kitchen has high end built in cooktop and ovens, also all brand new appliances. Living room is extra spacious. 3 car garage. This house is near the foothills library, foothills golf courses, the sheriffs station, the I-8. Outside features fire-pit, pool, bbq grill, sitting areas, fruit trees, and more! Great home to kick back and relax.

Spacious house with a modern kitchen + 4 bedrooms
This Beautiful house is perfect to bring family , friends or for a couple . This house offers you comfort and is secure , with a spacious patio to relax and enjoy the outdoors . There's an emergency medical center just around the corner . Pleasant area to walk in the morning or just enjoy a delicious barbecue in the afternoon on the patio . It's a 10-minute drive to the Border Crossing and 5-minute drive to a supermarket , restaurants and gyms .

Casa Victoria, private and comfortable. We take payments.
Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area
Popular amenities for San Luis house rentals
House rentals with a pool

Yuma Cozy Casita

Casa Vida

Sonora casa del Sol

Casa Bonita

Refreshing pool an Game Room

Pool+GameRoom | LargeYard+Pet Friendly

SunshineManor Heart of Yuma Heated Pool option

Green Relaxing Minimalist Home
Weekly house rentals

Camelias Apartment #2

Desert Oasis Minutes From MX Border

Casa México, private, safe and quiet

Casa Topaz, ideal for your stay, comfortable, safe

The house

"La casita" Cozy home away from home

Casa Zaragoza

4 seasons fun! Family retreat with themed rooms
Private house rentals

Beautiful house

Family Friendly Resort | Pool | Yard | Games

Family Home

Residence 1 block from the USA line

Cozy Spacious Casa Santa Maria

Modern Pet-Friendly Foothill Home

Casa Libertad -WiFi/AC/TV/Washing Machine/Dryer/Garage

Casa Libertad
When is the best time to visit San Luis?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$21,975 GYD | G$23,649 GYD | G$23,021 GYD | G$20,719 GYD | G$21,975 GYD | G$21,765 GYD | G$21,138 GYD | G$21,347 GYD | G$20,928 GYD | G$19,045 GYD | G$20,928 GYD | G$21,556 GYD |
| Avg. temp | 13°C | 15°C | 18°C | 21°C | 25°C | 30°C | 34°C | 34°C | 30°C | 24°C | 17°C | 12°C |
Quick stats about house rentals in San Luis

Total vacation rentals
Explore 100 vacation rentals in San Luis

Nightly prices starting at
San Luis vacation rentals start at G$4,186 GYD per night before taxes and fees

Verified guest reviews
Over 2,230 verified reviews to help you choose

Family-friendly vacation rentals
90 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
100 of San Luis vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis rentals

4.9 Average rating
San Luis stays are highly rated by guests—averaging 4.9 out of 5!
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- Pet-friendly rentals San Luis
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