
House vacation rentals in San Luis
Find and book unique houses on Airbnb
Quick stats about house rentals in San Luis

Total vacation rentals
Explore 100 vacation rentals in San Luis

Nightly prices starting at
San Luis vacation rentals start at G$4,184 GYD per night before taxes and fees

Verified guest reviews
Over 2,230 verified reviews to help you choose

Family-friendly vacation rentals
90 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
100 of San Luis vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis rentals

4.9 Average rating
San Luis stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in San Luis
Guests agree: these houses are highly rated for location, cleanliness, and more.

Mi Bonita Coquette
This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Private Desert Retreat | Pool, Arcade & RV Parking
Experience elevated comfort in this spacious, serene retreat. Thoughtfully crafted for business and leisure travelers, the home features brand-new Samsung smart appliances, a pool, an arcade game, and a grill/smoker. Enjoy refined indoor comfort, stylish gathering spaces, ample parking for up to 5 vehicles (including RVs and desert vehicles), and step-free entry for wheelchairs, power chairs & walkers. Whether lounging poolside or unwinding indoors, this property offers a truly exceptional stay

Desert Escape Heated Pool/2king beds/ Toy parking
Year-Round Comfort and Relaxation in Yuma Escape the summer heat or bask in the warm winter sun in this private, tranquil retreat. This spacious home offers everything you need to unwind and enjoy your time in Yuma. 2 king beds & 2.5 baths there is plenty of space. Conveniently located close to I-8 shopping, dining, and fuel. Whether you are looking to relax in the sun, cool off in the pool, or enjoy time with family and friends, this is the perfect place to make the most of your stay in Yuma.

Yuma’s Best | Pet Friendly | Snowbirds Welcome
Modern desert retreat in the clean, quiet Lynwood neighborhood of Yuma. Open layout with high ceilings and dome skylights that bring in natural light without added desert heat. Ideal for snowbirds, families, traveling professionals, and guests visiting Algodones for dental care (18 mins). Pet-friendly with private backyard patio—perfect for relaxing mornings and evening grilling. High-speed reliable WiFi, Spectrum cable TV + streaming. Close to shopping, golf, dunes, and Los Algodones, MX.

Bright 4 bedroom home in the heart of town.
This 4 bedroom getaway brings all the comforts of home to your vacation. With the ability to comfortably sleep 10 people there’s plenty of room for you and your friends or family. Enjoy an evening of dinner under the lit gazebo and s’mores around the fire pit or hit the town and check out all the Yuma has to offer. This home is centrally located so you’re never far from food and drinks. Just a 20 minute drive to the dunes, a 15 minute drive to Mexico and a one minute walk down to the park.

Modern Pet friendly Home, w/backyard/ trlr parking
Welcome to The Stay! Your modern, home-away-from-home. Whether you’re visiting for work or play, you’ll love the comfort, convenience and amenities this home offers. Just 10 minutes from Downtown, or the Foothills, The Stay puts you close to everything. Enjoy a fully landscaped backyard for relaxing evenings, 2-car garage, and gated access for trailers. This home is Pet friendly, So your four-legged family members are welcome too! The Stay is sure to make your time in Yuma comfortable.

The Dandy House: A Stunning 3-Bedroom Charmer
This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.

Newly Remodeled Home In The Heart Of Somerton
This newly remodeled home features three bedrooms and 2 full bathrooms. New flooring has been installed throughout the entire house The new kitchen includes pots and pans for you to enjoy a home cooked meal if you so desire. This cozy home located in the downtown/entertainment district of "the best little city in Arizona" has a living room equipped with a smart tv and wi-fi internet in the entire home. Dining and entertainment is within walking distance of this beautiful home.

Tuscany Style Casita
Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Welcome To Our Cozy Home! Fully Equipped 3BR/2BA
Welcome to our cozy home! Enjoy this incredible clean and modern home. This home is ready for cooking, sleeping and enjoying the amazing Yuma sunshine. Our nearest shopping center is 2 miles away! We have a Walmart, Albertsons, Taco Bell…The marine base is 4 miles, the border of Algodones is 20 minutes drive. Locate in a safe and family neighborhood. Home is equipped with a fully accessible closet to ensure confort for longer stay.Just 4 miles to downtown Yuma and Hwy 8!

Casa Victoria, private and comfortable. We take payments.
Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area

LUXURY Living!
You will enjoy your stay at this fully furnished LUXURY rental. It has 4 bedrooms, 2 bathrooms and is located on a quiet cul-de-sac. Relax on the large covered patio, next to the pool, or by fire pit. Great location in the center of town near the hospital, golf courses, shopping, and restaurants. You are just a short drive away from Mexico, Colorado River, sand dunes, and hiking.
Popular amenities for San Luis house rentals
House rentals with a pool

My Saguaro Casita/private pool

Meraki Vacation Home Pool sleeps 10

Casa Bonita

Little Sedona in San Luis 3 Bedrooms Pool & Grill

Casa Blanca

SunshineManor Heart of Yuma Heated Pool option

Green Relaxing Minimalist Home

Cute Pool Home Near Duck Park
Weekly house rentals

Blue house

Desert Oasis Minutes From MX Border

Casa Topaz, ideal for your stay, comfortable, safe

The house

Casa Libertad

"La casita" Cozy home away from home

Pura Vida House!

Mili’s Home – Unit A | Cozy Peaceful Tiny Home
Private house rentals

🏜Little Casita, Big Comfort! Minutes from border.

Spacious Getaway with Mountain Views

Family Home

Casa Libertad -WiFi/AC/TV/Washing Machine/Dryer/Garage

Casa México, private, safe and quiet

Yuma Valley Casa

LUX Modern Lovely Casita- 3BR/2BA

Cozy House 10 minutes from the border
When is the best time to visit San Luis?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$21,966 GYD | G$23,640 GYD | G$23,012 GYD | G$20,711 GYD | G$21,966 GYD | G$21,757 GYD | G$21,129 GYD | G$21,338 GYD | G$20,920 GYD | G$19,037 GYD | G$20,920 GYD | G$21,548 GYD |
| Avg. temp | 13°C | 15°C | 18°C | 21°C | 25°C | 30°C | 34°C | 34°C | 30°C | 24°C | 17°C | 12°C |
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- Rentals with a patio San Luis
- Rentals with a fire pit San Luis
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