
House vacation rentals in San Luis
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Top-rated house rentals in San Luis
Guests agree: these houses are highly rated for location, cleanliness, and more.

Cozy Foothills Retreat 3BD/2 Bath/Hot Tub/Cable TV
Perfect for families, couples, winter visitors, and traveling professionals, this home offers the ideal mix of comfort and relaxation. After a day of exploring or working unwind in the private hot tub and enjoy Arizona evenings on the patio. Relax comfortably indoors in reclining sofas in the main living room, big screen TV in the main living room. Play a game of pool or retire to a space all your in your private room or the second living room with a comfortable leather sofa and big screen TV.

Mi Bonita Coquette
This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Private Desert Retreat | Pool, Arcade & RV Parking
Experience elevated comfort in this spacious, serene retreat. Thoughtfully crafted for business and leisure travelers, the home features brand-new Samsung smart appliances, a pool, an arcade game, and a grill/smoker. Enjoy refined indoor comfort, stylish gathering spaces, ample parking for up to 5 vehicles (including RVs and desert vehicles), and step-free entry for wheelchairs, power chairs & walkers. Whether lounging poolside or unwinding indoors, this property offers a truly exceptional stay

Yuma’s Best | Pet Friendly | Snowbirds Welcome
Modern desert retreat in the clean, quiet Lynwood neighborhood of Yuma. Open layout with high ceilings and dome skylights that bring in natural light without added desert heat. Ideal for snowbirds, families, traveling professionals, and guests visiting Algodones for dental care (18 mins). Pet-friendly with private backyard patio—perfect for relaxing mornings and evening grilling. High-speed reliable WiFi, Spectrum cable TV + streaming. Close to shopping, golf, dunes, and Los Algodones, MX.

Modern Pet friendly Home, w/backyard/ trlr parking
Welcome to The Stay! Your modern, home-away-from-home. Whether you’re visiting for work or play, you’ll love the comfort, convenience and amenities this home offers. Just 10 minutes from Downtown, or the Foothills, The Stay puts you close to everything. Enjoy a fully landscaped backyard for relaxing evenings, 2-car garage, and gated access for trailers. This home is Pet friendly, So your four-legged family members are welcome too! The Stay is sure to make your time in Yuma comfortable.

The Dandy House: A Stunning 3-Bedroom Charmer
This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.

Newly Remodeled Home In The Heart Of Somerton
This newly remodeled home features three bedrooms and 2 full bathrooms. New flooring has been installed throughout the entire house The new kitchen includes pots and pans for you to enjoy a home cooked meal if you so desire. This cozy home located in the downtown/entertainment district of "the best little city in Arizona" has a living room equipped with a smart tv and wi-fi internet in the entire home. Dining and entertainment is within walking distance of this beautiful home.

Large beautiful 3 bedroom pool home
Located in a beautiful and quiet subdivision this home boasts a large floor plan with plenty of room for a group of 10 and a sparkling pool. We’ve put a lot of thought into your stay with amenities like cold drinking water, a BBQ and washer and dryer to help you enjoy your stay, relax and unwind. Throw in a bath bomb (provided) and enjoy a soak in the tub or lay out pool side with a glass of wine. Master holds a king bed, 2nd room a queen, and 2 bunks with trundles in the 3rd.

Tuscany Style Casita
Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Welcome To Our Cozy Home! Fully Equipped 3BR/2BA
Welcome to our cozy home! Enjoy this incredible clean and modern home. This home is ready for cooking, sleeping and enjoying the amazing Yuma sunshine. Our nearest shopping center is 2 miles away! We have a Walmart, Albertsons, Taco Bell…The marine base is 4 miles, the border of Algodones is 20 minutes drive. Locate in a safe and family neighborhood. Home is equipped with a fully accessible closet to ensure confort for longer stay.Just 4 miles to downtown Yuma and Hwy 8!

Beautiful Pool Home in Yuma Foothills!
Enjoy your stay at this modern pool home in Yuma! This property features 2 large master suites, each room has a king bed and sofa bed. Kitchen has high end built in cooktop and ovens, also all brand new appliances. Living room is extra spacious. 3 car garage. This house is near the foothills library, foothills golf courses, the sheriffs station, the I-8. Outside features fire-pit, pool, bbq grill, sitting areas, fruit trees, and more! Great home to kick back and relax.

Casa Victoria, private and comfortable. We take payments.
Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area
Popular amenities for San Luis house rentals
House rentals with a pool

My Saguaro Casita/private pool

Residence 1 block from the USA line

Casa Vida

Sonora casa del Sol

Casa Bonita

Pool+GameRoom | LargeYard+Pet Friendly

Little Sedona in San Luis 3 Bedrooms Pool & Grill

Casa Blanca
Weekly house rentals

Family Home

Casa Libertad -WiFi/AC/TV/Washing Machine/Dryer/Garage

Casa México, private, safe and quiet

House with covered garage/barbecue

Cozy House 10 minutes from the border

Casa Zaragoza

Yuma Foothills

4 seasons fun! Family retreat with themed rooms
Private house rentals

Yuma Valley Atrium Retreat

Brecha Apartment (We bill)

Entire house in the center of the city

Entire House • 3 Bedrooms • Self Check-In”

Modern Pet-Friendly Foothill Home

Modern cabin-style house

Yuma Valley Casa

LUX Modern Lovely Casita- 3BR/2BA
When is the best time to visit San Luis?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$21,950 GYD | G$23,623 GYD | G$22,996 GYD | G$20,696 GYD | G$21,950 GYD | G$21,741 GYD | G$21,114 GYD | G$21,323 GYD | G$20,905 GYD | G$19,024 GYD | G$20,905 GYD | G$21,532 GYD |
| Avg. temp | 13°C | 15°C | 18°C | 21°C | 25°C | 30°C | 34°C | 34°C | 30°C | 24°C | 17°C | 12°C |
Quick stats about house rentals in San Luis

Total vacation rentals
Explore 100 vacation rentals in San Luis

Nightly prices starting at
San Luis vacation rentals start at G$4,181 GYD per night before taxes and fees

Verified guest reviews
Over 2,230 verified reviews to help you choose

Family-friendly vacation rentals
90 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
100 of San Luis vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis rentals

4.9 Average rating
San Luis stays are highly rated by guests—averaging 4.9 out of 5!
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