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House vacation rentals in San Luis

Find and book unique houses on Airbnb

Quick stats about house rentals in San Luis

  • Total vacation rentals

    Explore 100 vacation rentals in San Luis

  • Nightly prices starting at

    San Luis vacation rentals start at G$4,183 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,230 verified reviews to help you choose

  • Family-friendly vacation rentals

    90 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

  • Wi-Fi availability

    100 of San Luis vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis rentals

  • 4.9 Average rating

    San Luis stays are highly rated by guests—averaging 4.9 out of 5!

Top-rated house rentals in San Luis

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
A contemporary home features a warm wooden front door, complimented by stone accents. A well-maintained lawn with tiered landscaping leads up to the entrance. Large windows allow natural light to illuminate the interior, while a two-car garage is visible on one side.
Home in San Luis
5 out of 5 average rating, 34 reviews

Mi Bonita Coquette

This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Top guest favorite
A private pool area features tranquil blue water under a shaded patio. Comfortable lounge chairs are positioned nearby, with an umbrella providing additional shade. A table with chairs is visible on the patio, creating an inviting space for relaxation.
Home in Yuma
5 out of 5 average rating, 164 reviews

Desert Escape Heated Pool/2king beds/ Toy parking

Year-Round Comfort and Relaxation in Yuma Escape the summer heat or bask in the warm winter sun in this private, tranquil retreat. This spacious home offers everything you need to unwind and enjoy your time in Yuma. 2 king beds & 2.5 baths there is plenty of space. Conveniently located close to I-8 shopping, dining, and fuel. Whether you are looking to relax in the sun, cool off in the pool, or enjoy time with family and friends, this is the perfect place to make the most of your stay in Yuma.

Guest favorite
Home in Yuma
4.95 out of 5 average rating, 134 reviews

Yuma’s Best | Pet Friendly | Snowbirds Welcome

Modern desert retreat in the clean, quiet Lynwood neighborhood of Yuma. Open layout with high ceilings and dome skylights that bring in natural light without added desert heat. Ideal for snowbirds, families, traveling professionals, and guests visiting Algodones for dental care (18 mins). Pet-friendly with private backyard patio—perfect for relaxing mornings and evening grilling. High-speed reliable WiFi, Spectrum cable TV + streaming. Close to shopping, golf, dunes, and Los Algodones, MX.

Superhost
The front view of a single-story home showcases a welcoming entrance with a covered porch. Two chairs are positioned beside the door, flanked by potted plants. A spacious gravel area is visible in front, providing ample parking space.
Home in Yuma
4.91 out of 5 average rating, 108 reviews

Bright 4 bedroom home in the heart of town.

This 4 bedroom getaway brings all the comforts of home to your vacation. With the ability to comfortably sleep 10 people there’s plenty of room for you and your friends or family. Enjoy an evening of dinner under the lit gazebo and s’mores around the fire pit or hit the town and check out all the Yuma has to offer. This home is centrally located so you’re never far from food and drinks. Just a 20 minute drive to the dunes, a 15 minute drive to Mexico and a one minute walk down to the park.

Top guest favorite
The modern exterior of the home features a clean façade with a spacious driveway leading to a two-car garage. A well-maintained lawn and pathway enhance the welcoming appearance. The entrance is highlighted by a covered porch and decorative elements, indicating attention to detail.
Home in Yuma
4.97 out of 5 average rating, 115 reviews

Modern Pet friendly Home, w/backyard/ trlr parking

Welcome to The Stay! Your modern, home-away-from-home. Whether you’re visiting for work or play, you’ll love the comfort, convenience and amenities this home offers. Just 10 minutes from Downtown, or the Foothills, The Stay puts you close to everything. Enjoy a fully landscaped backyard for relaxing evenings, 2-car garage, and gated access for trailers. This home is Pet friendly, So your four-legged family members are welcome too! The Stay is sure to make your time in Yuma comfortable.

Top guest favorite
A dining area features a large wooden table adorned with a vibrant arrangement of red flowers in a white vase. The space is illuminated by a rustic chandelier, and a decorative wall displays the name 'The Dandy House' beside a barn-style door.
Home in Yuma
4.99 out of 5 average rating, 131 reviews

The Dandy House: A Stunning 3-Bedroom Charmer

This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.

Guest favorite
A spacious living area features a large sectional sofa adorned with decorative pillows in soft colors. Framed artwork of tropical leaves complements the neutral wall, and light curtains frame the window. A textured area rug adds warmth to the floor.
Home in San Luis
4.93 out of 5 average rating, 46 reviews

San Luis,Arizona- Centrally located-7min to border

Casa Arizona is located in the heart of San luis Az, easy access to everything from this centrally located place. Less than 7 min from the San Luis Rio Colorado border. 25 min from Yuma. Our place is perfect to host comfortably up to 5 people. Washer and Dryer for your convenience. Short and long stays are welcome. Note: You are renting the main house. We also have an studio on the property with its own private entrance and patio. Both spaces are designed for a relaxing experience.

Superhost
A modern single-story home is visible, featuring a light-colored exterior and a stone accent wall. A wide concrete pathway leads to the entrance, framed by a low fence. The property is situated in a neighborhood with clear views of the street and nearby structures.
Home in Somerton
4.84 out of 5 average rating, 137 reviews

Newly Remodeled Home In The Heart Of Somerton

This newly remodeled home features three bedrooms and 2 full bathrooms. New flooring has been installed throughout the entire house The new kitchen includes pots and pans for you to enjoy a home cooked meal if you so desire. This cozy home located in the downtown/entertainment district of "the best little city in Arizona" has a living room equipped with a smart tv and wi-fi internet in the entire home. Dining and entertainment is within walking distance of this beautiful home.

Top guest favorite
A spacious bedroom features a comfortable bed dressed in neutral tones with decorative pillows. Two mirrors reflect natural light from a window framed by simple blinds. A textured rug complements the wood flooring, while a dresser and nightstands add functional decor.
Home in Yuma
4.98 out of 5 average rating, 237 reviews

Tuscany Style Casita

Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Guest favorite
A cozy living area features two brown sofas with accent pillows, positioned around a central coffee table. Natural light enters through large sliding doors, which are framed by floor-to-ceiling curtains. A green plant adds a touch of nature to the space.
Home in Yuma
4.93 out of 5 average rating, 128 reviews

Welcome To Our Cozy Home! Fully Equipped 3BR/2BA

Welcome to our cozy home! Enjoy this incredible clean and modern home. This home is ready for cooking, sleeping and enjoying the amazing Yuma sunshine. Our nearest shopping center is 2 miles away! We have a Walmart, Albertsons, Taco Bell…The marine base is 4 miles, the border of Algodones is 20 minutes drive. Locate in a safe and family neighborhood. Home is equipped with a fully accessible closet to ensure confort for longer stay.Just 4 miles to downtown Yuma and Hwy 8!

Guest favorite
A modern single-story home is showcased from the street, featuring a light-colored exterior and a gabled roof. The driveway leads to a three-car garage, with desert landscaping visible, including palm trees and various shrubs. Mountains are faintly visible in the background.
Home in Yuma
4.95 out of 5 average rating, 226 reviews

Beautiful Pool Home in Yuma Foothills!

Enjoy your stay at this modern pool home in Yuma! This property features 2 large master suites, each room has a king bed and sofa bed. Kitchen has high end built in cooktop and ovens, also all brand new appliances. Living room is extra spacious. 3 car garage. This house is near the foothills library, foothills golf courses, the sheriffs station, the I-8. Outside features fire-pit, pool, bbq grill, sitting areas, fruit trees, and more! Great home to kick back and relax.

Top guest favorite
Home in San Luis Río Colorado
4.97 out of 5 average rating, 115 reviews

Casa Victoria, private and comfortable. We take payments.

Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area

Popular amenities for San Luis house rentals

When is the best time to visit San Luis?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$21,962 GYDG$23,635 GYDG$23,007 GYDG$20,707 GYDG$21,962 GYDG$21,752 GYDG$21,125 GYDG$21,334 GYDG$20,916 GYDG$19,033 GYDG$20,916 GYDG$21,543 GYD
Avg. temp13°C15°C18°C21°C25°C30°C34°C34°C30°C24°C17°C12°C
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