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House vacation rentals in San Luis

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Top-rated house rentals in San Luis

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
Home in San Luis
4.96 out of 5 average rating, 52 reviews

Luxury" Home" 5 minutes from the border sleeps 6

This luxury home is designed thinking of our guest experience, cozy and comfortable . You will enjoy the indoor and outdoor areas great for a couples getaway asome for family time and lovely for having the house for yourself. Enjoy yourselves it’s an open layout well designed with unique charm a full kitchen super comfortable couch for movie night. outdoor is the perfect space to have a drink and relax its your home away from home Two private airbnbs with private entrance and private back yards

Guest favorite
A contemporary home features a warm wooden front door, complimented by stone accents. A well-maintained lawn with tiered landscaping leads up to the entrance. Large windows allow natural light to illuminate the interior, while a two-car garage is visible on one side.
Home in San Luis
5 out of 5 average rating, 33 reviews

Mi Bonita Coquette

This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Guest favorite
Home in Yuma
4.95 out of 5 average rating, 133 reviews

Yuma’s Best | Pet Friendly | Snowbirds Welcome

Modern desert retreat in the clean, quiet Lynwood neighborhood of Yuma. Open layout with high ceilings and dome skylights that bring in natural light without added desert heat. Ideal for snowbirds, families, traveling professionals, and guests visiting Algodones for dental care (18 mins). Pet-friendly with private backyard patio—perfect for relaxing mornings and evening grilling. High-speed reliable WiFi, Spectrum cable TV + streaming. Close to shopping, golf, dunes, and Los Algodones, MX.

Top guest favorite
The modern exterior of the home features a clean façade with a spacious driveway leading to a two-car garage. A well-maintained lawn and pathway enhance the welcoming appearance. The entrance is highlighted by a covered porch and decorative elements, indicating attention to detail.
Home in Yuma
4.97 out of 5 average rating, 115 reviews

Modern Pet friendly Home, w/backyard/ trlr parking

Welcome to The Stay! Your modern, home-away-from-home. Whether you’re visiting for work or play, you’ll love the comfort, convenience and amenities this home offers. Just 10 minutes from Downtown, or the Foothills, The Stay puts you close to everything. Enjoy a fully landscaped backyard for relaxing evenings, 2-car garage, and gated access for trailers. This home is Pet friendly, So your four-legged family members are welcome too! The Stay is sure to make your time in Yuma comfortable.

Top guest favorite
A dining area features a large wooden table adorned with a vibrant arrangement of red flowers in a white vase. The space is illuminated by a rustic chandelier, and a decorative wall displays the name 'The Dandy House' beside a barn-style door.
Home in Yuma
4.99 out of 5 average rating, 131 reviews

The Dandy House: A Stunning 3-Bedroom Charmer

This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.

Superhost
A modern single-story home is visible, featuring a light-colored exterior and a stone accent wall. A wide concrete pathway leads to the entrance, framed by a low fence. The property is situated in a neighborhood with clear views of the street and nearby structures.
Home in Somerton
4.84 out of 5 average rating, 137 reviews

Newly Remodeled Home In The Heart Of Somerton

This newly remodeled home features three bedrooms and 2 full bathrooms. New flooring has been installed throughout the entire house The new kitchen includes pots and pans for you to enjoy a home cooked meal if you so desire. This cozy home located in the downtown/entertainment district of "the best little city in Arizona" has a living room equipped with a smart tv and wi-fi internet in the entire home. Dining and entertainment is within walking distance of this beautiful home.

Guest favorite
A single-story home is presented with a tiled roof and stone accents. Lush greenery frames the entrance, with gravel landscaping surrounding the property. A driveway leads to a garage, and a rock feature adds a natural element to the front yard.
Home in Yuma
4.84 out of 5 average rating, 118 reviews

Large beautiful 3 bedroom pool home

Located in a beautiful and quiet subdivision this home boasts a large floor plan with plenty of room for a group of 10 and a sparkling pool. We’ve put a lot of thought into your stay with amenities like cold drinking water, a BBQ and washer and dryer to help you enjoy your stay, relax and unwind. Throw in a bath bomb (provided) and enjoy a soak in the tub or lay out pool side with a glass of wine. Master holds a king bed, 2nd room a queen, and 2 bunks with trundles in the 3rd.

Top guest favorite
A spacious bedroom features a comfortable bed dressed in neutral tones with decorative pillows. Two mirrors reflect natural light from a window framed by simple blinds. A textured rug complements the wood flooring, while a dresser and nightstands add functional decor.
Home in Yuma
4.98 out of 5 average rating, 237 reviews

Tuscany Style Casita

Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Guest favorite
A cozy living area features two brown sofas with accent pillows, positioned around a central coffee table. Natural light enters through large sliding doors, which are framed by floor-to-ceiling curtains. A green plant adds a touch of nature to the space.
Home in Yuma
4.93 out of 5 average rating, 128 reviews

Welcome To Our Cozy Home! Fully Equipped 3BR/2BA

Welcome to our cozy home! Enjoy this incredible clean and modern home. This home is ready for cooking, sleeping and enjoying the amazing Yuma sunshine. Our nearest shopping center is 2 miles away! We have a Walmart, Albertsons, Taco Bell…The marine base is 4 miles, the border of Algodones is 20 minutes drive. Locate in a safe and family neighborhood. Home is equipped with a fully accessible closet to ensure confort for longer stay.Just 4 miles to downtown Yuma and Hwy 8!

Top guest favorite
Home in San Luis Río Colorado
4.97 out of 5 average rating, 115 reviews

Casa Victoria, private and comfortable. We take payments.

Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area

Guest favorite
A bright living area features a comfortable sectional sofa and a patterned area rug. Natural light filters through sheer curtains, illuminating the space. A stylish cabinet houses a TV, while potted plants add a touch of greenery to the inviting atmosphere.
Home in Yuma
4.94 out of 5 average rating, 407 reviews

LUXURY Living!

You will enjoy your stay at this fully furnished LUXURY rental. It has 4 bedrooms, 2 bathrooms and is located on a quiet cul-de-sac. Relax on the large covered patio, next to the pool, or by fire pit. Great location in the center of town near the hospital, golf courses, shopping, and restaurants. You are just a short drive away from Mexico, Colorado River, sand dunes, and hiking.

Guest favorite
Home in Yuma
4.82 out of 5 average rating, 187 reviews

Yuma Cozy Casita

Enjoy our cozy home. Less than a mile away from the Yuma airport. We welcome you to come to enjoy The beautiful weather yuma has to offer in the winter. You will also have a dedicated workspace with a desk. Close to all your shopping needs. Algodones is about 25 minutes, and San Luis Mexico is approx. 45 minutes. Please note that the POOL IS NOT GATED, NOR HEATED.

Popular amenities for San Luis house rentals

When is the best time to visit San Luis?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$21,949 GYDG$23,621 GYDG$22,994 GYDG$20,695 GYDG$21,949 GYDG$21,740 GYDG$21,113 GYDG$21,322 GYDG$20,904 GYDG$19,022 GYDG$20,904 GYDG$21,531 GYD
Avg. temp13°C15°C18°C21°C25°C30°C34°C34°C30°C24°C17°C12°C

Quick stats about house rentals in San Luis

  • Total vacation rentals

    Explore 100 vacation rentals in San Luis

  • Nightly prices starting at

    San Luis vacation rentals start at G$4,181 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,230 verified reviews to help you choose

  • Family-friendly vacation rentals

    90 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

  • Wi-Fi availability

    100 of San Luis vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis rentals

  • 4.9 Average rating

    San Luis stays are highly rated by guests—averaging 4.9 out of 5!

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