
House vacation rentals in San Luis
Find and book unique houses on Airbnb
Quick stats about house rentals in San Luis

Total vacation rentals
Explore 100 vacation rentals in San Luis

Nightly prices starting at
San Luis vacation rentals start at G$4,185 GYD per night before taxes and fees

Verified guest reviews
Over 2,230 verified reviews to help you choose

Family-friendly vacation rentals
90 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
100 of San Luis vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis rentals

4.9 Average rating
San Luis stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in San Luis
Guests agree: these houses are highly rated for location, cleanliness, and more.

Luxury" Home" 5 minutes from the border sleeps 6
This luxury home is designed thinking of our guest experience, cozy and comfortable . You will enjoy the indoor and outdoor areas great for a couples getaway asome for family time and lovely for having the house for yourself. Enjoy yourselves it’s an open layout well designed with unique charm a full kitchen super comfortable couch for movie night. outdoor is the perfect space to have a drink and relax its your home away from home Two private airbnbs with private entrance and private back yards

Cozy Foothills Retreat 3BD/2 Bath/Hot Tub/Cable TV
Perfect for families, couples, winter visitors, and traveling professionals, this home offers the ideal mix of comfort and relaxation. After a day of exploring or working unwind in the private hot tub and enjoy Arizona evenings on the patio. Relax comfortably indoors in reclining sofas in the main living room, big screen TV in the main living room. Play a game of pool or retire to a space all your in your private room or the second living room with a comfortable leather sofa and big screen TV.

Mi Bonita Coquette
This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Desert Oasis Minutes From MX Border
Relax with the whole family at this peaceful place to stay. Only minutes away from the US/Mexico border! Our home is located in a new construction neighborhood. Modernly decorated and cozy feel all throughout. Full access to 2 car garage, spacious rear patio and full kitchen. Nearby attractions include MX for some day shopping or tacos, Waylon's Water World, West Wetlands Park, Cocopah R.C Golf Course & Casino and let's not forget, many off roading areas if you want to bring off roading toys!

Yuma’s Best | Pet Friendly | Snowbirds Welcome
Modern desert retreat in the clean, quiet Lynwood neighborhood of Yuma. Open layout with high ceilings and dome skylights that bring in natural light without added desert heat. Ideal for snowbirds, families, traveling professionals, and guests visiting Algodones for dental care (18 mins). Pet-friendly with private backyard patio—perfect for relaxing mornings and evening grilling. High-speed reliable WiFi, Spectrum cable TV + streaming. Close to shopping, golf, dunes, and Los Algodones, MX.

San Luis,Arizona- Centrally located-7min to border
Casa Arizona is located in the heart of San luis Az, easy access to everything from this centrally located place. Less than 7 min from the San Luis Rio Colorado border. 25 min from Yuma. Our place is perfect to host comfortably up to 5 people. Washer and Dryer for your convenience. Short and long stays are welcome. Note: You are renting the main house. We also have an studio on the property with its own private entrance and patio. Both spaces are designed for a relaxing experience.

Large beautiful 3 bedroom pool home
Located in a beautiful and quiet subdivision this home boasts a large floor plan with plenty of room for a group of 10 and a sparkling pool. We’ve put a lot of thought into your stay with amenities like cold drinking water, a BBQ and washer and dryer to help you enjoy your stay, relax and unwind. Throw in a bath bomb (provided) and enjoy a soak in the tub or lay out pool side with a glass of wine. Master holds a king bed, 2nd room a queen, and 2 bunks with trundles in the 3rd.

Tuscany Style Casita
Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Welcome To Our Cozy Home! Fully Equipped 3BR/2BA
Welcome to our cozy home! Enjoy this incredible clean and modern home. This home is ready for cooking, sleeping and enjoying the amazing Yuma sunshine. Our nearest shopping center is 2 miles away! We have a Walmart, Albertsons, Taco Bell…The marine base is 4 miles, the border of Algodones is 20 minutes drive. Locate in a safe and family neighborhood. Home is equipped with a fully accessible closet to ensure confort for longer stay.Just 4 miles to downtown Yuma and Hwy 8!

Spacious house with a modern kitchen + 4 bedrooms
This Beautiful house is perfect to bring family , friends or for a couple . This house offers you comfort and is secure , with a spacious patio to relax and enjoy the outdoors . There's an emergency medical center just around the corner . Pleasant area to walk in the morning or just enjoy a delicious barbecue in the afternoon on the patio . It's a 10-minute drive to the Border Crossing and 5-minute drive to a supermarket , restaurants and gyms .

Casa Victoria, private and comfortable. We take payments.
Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area

Yuma Cozy Casita
Enjoy our cozy home. Less than a mile away from the Yuma airport. We welcome you to come to enjoy The beautiful weather yuma has to offer in the winter. You will also have a dedicated workspace with a desk. Close to all your shopping needs. Algodones is about 25 minutes, and San Luis Mexico is approx. 45 minutes. Please note that the POOL IS NOT GATED, NOR HEATED.
Popular amenities for San Luis house rentals
House rentals with a pool

My Saguaro Casita/private pool

Perfect for Families & Groups in Fortuna Foothills

Private Desert Retreat | Pool, Arcade & RV Parking

Casa Vida

Casa Bonita

Pool+GameRoom | LargeYard+Pet Friendly

SunshineManor Heart of Yuma Heated Pool option

Green Relaxing Minimalist Home
Weekly house rentals

Casa Luna Near YPG & MCAS

Camelias Apartment #2

Entire House • 3 Bedrooms • Self Check-In”

Casa Topaz, ideal for your stay, comfortable, safe

The house

Centrally located in the heart of Yuma

"La casita" Cozy home away from home

Mili’s Home – Unit A | Cozy Peaceful Tiny Home
Private house rentals

Cottage

Family Home

Cozy Spacious Casa Santa Maria Entire Home

Casa Libertad -WiFi/AC/TV/Washing Machine/Dryer/Garage

Casa México, private, safe and quiet

Casa Libertad

House with covered garage/barbecue

Casa Zaragoza
When is the best time to visit San Luis?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$21,972 GYD | G$23,646 GYD | G$23,018 GYD | G$20,716 GYD | G$21,972 GYD | G$21,762 GYD | G$21,135 GYD | G$21,344 GYD | G$20,925 GYD | G$19,042 GYD | G$20,925 GYD | G$21,553 GYD |
| Avg. temp | 13°C | 15°C | 18°C | 21°C | 25°C | 30°C | 34°C | 34°C | 30°C | 24°C | 17°C | 12°C |
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