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Vacation rentals in San Luis

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in San Luis

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A contemporary home features a warm wooden front door, complimented by stone accents. A well-maintained lawn with tiered landscaping leads up to the entrance. Large windows allow natural light to illuminate the interior, while a two-car garage is visible on one side.
Home in San Luis
5 out of 5 average rating, 32 reviews

Mi Bonita Coquette

This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Top guest favorite
A dining area features a large wooden table adorned with a vibrant arrangement of red flowers in a white vase. The space is illuminated by a rustic chandelier, and a decorative wall displays the name 'The Dandy House' beside a barn-style door.
Home in Yuma
5 out of 5 average rating, 128 reviews

The Dandy House: A Stunning 3-Bedroom Charmer

This property is an extension of our local boutique in Yuma, Dandy Home and Ranch. Enjoy a stylish and cozy stay, as Dandy invites you to experience hospitality and inspiration, whether you are traveling for work or for pleasure. We are located just down the street from the hospital, and we are just steps away from Starbucks, and other convenient amenities. We invite you to relax in the backyard by the fire pit, cook an amazing meal, or cozy up by the fireplace, all in Dandy style.

Guest favorite
A cozy living area is highlighted by a sofa, decorated with a vibrant green cushion. A small table holds decorative items, and large glass doors open to a private pool area, framed by greenery and natural light.
Apartment in San Luis
4.96 out of 5 average rating, 140 reviews

Heated Pool, 2 Queen beds private apartment Enjoy

The property is divided in to two airbnbs with there own private entrence and private backyard grill outdoor dining and fire pit lounge area. None of the areas are shared they are 100% privateEnjoy your time at this stylish place make great memories at the poolside !! Pool is totally private for this unit in winter season pool temperature can vary depending on the weather outside it’s not a close pool heater is normally on from Nov to May. Enjoy your time in this special place.

Guest favorite
The outdoor area features a private solar heated pool with a unique shape, surrounded by a spacious patio. Comfortable seating areas, including lounge chairs and a dining set, are arranged under a covered patio, complemented by well-maintained landscaping.
Home in Yuma
4.94 out of 5 average rating, 115 reviews

Private Desert Retreat | Pool, Arcade & RV Parking

Experience elevated comfort in this spacious, serene retreat, thoughtfully designed for discerning business and leisure travelers. Ideally located, the home features brand-new Samsung smart appliances, a swimming pool, an arcade game, and a grill/smoker. Enjoy refined indoor comfort, stylish gathering spaces, and ample parking for up to five vehicles, including RVs and desert vehicles. Whether lounging poolside or unwinding indoors, this property offers a truly exceptional stay.

Top guest favorite
A modern living area showcases a comfortable gray sofa adorned with orange accent pillows, accompanied by a cozy armchair. A round coffee table rests on a soft area rug. A flat-screen TV is mounted on the wall above a fireplace, with decorative plants and a woven basket nearby.
Home in Yuma
4.98 out of 5 average rating, 233 reviews

Tuscany Style Casita

Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Guest favorite
A cozy living area features two brown sofas with accent pillows, positioned around a central coffee table. Natural light enters through large sliding doors, which are framed by floor-to-ceiling curtains. A green plant adds a touch of nature to the space.
Home in Yuma
4.93 out of 5 average rating, 126 reviews

Welcome To Our Cozy Home! Fully Equipped 3BR/2BA

Welcome to our cozy home! Enjoy this incredible clean and modern home. This home is ready for cooking, sleeping and enjoying the amazing Yuma sunshine. Our nearest shopping center is 2 miles away! We have a Walmart, Albertsons, Taco Bell…The marine base is 4 miles, the border of Algodones is 20 minutes drive. Locate in a safe and family neighborhood. Home is equipped with a fully accessible closet to ensure confort for longer stay.Just 4 miles to downtown Yuma and Hwy 8!

Guest favorite
Tiny home in Yuma
4.87 out of 5 average rating, 157 reviews

Santa Fe 4 Tiny Studio

Welcome to Casa Santa Fe #4! "This boutique hotel-themed house" offers everything from single to double rooms. Santa Fe #4 is a cosy one-room studio that's fully equipped for a wonderful stay. Our fantastic communal pool area is all set for enjoyment! Just a quick note, if you fancy a dip in the jacuzzi, it does come with an extra fee of $40 USD. We've tailored everything here to provide you with a serene and peaceful stay. We're so excited for your visit!

Top guest favorite
A spacious bed is placed against a soft blue wall, featuring a neutral quilt and decorative striped pillow. Natural light is captured through a window with light curtains, enhancing the calming ambiance of the room, complemented by a macramé wall hanging.
Apartment in San Luis
5 out of 5 average rating, 32 reviews

Private Studio | Quiet & Comfy | Separate Entry

This charming 1-bed / 1-bath Studio offers a cozy and inviting space perfect for anyone seeking comfort and convenience. Ideally located near the border, convenience stores. The studio features a well-equipped kitchenette, allowing for simple meal preparation, and a bright, open layout that maximizes space. With its central location, you're just moments away from everything you need, 5 min from the border with Mexico and 25 min from Yuma, Az.

Top guest favorite
Home in San Luis Río Colorado
4.97 out of 5 average rating, 112 reviews

Casa Victoria, It's a pleasure to welcome you

Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area

Guest favorite
A fully equipped kitchen is shown, featuring wooden cabinets, a refrigerator, and a gas stove. A microwave sits on the counter, along with a coffee maker. A dining table, with decorative placemats, offers seating for multiple guests.
Home in San Luis
4.94 out of 5 average rating, 51 reviews

Retro vacation house.

This Retro House is located in the heart of San luis Az, easy access to everything. Right across Walmart, Dollar tree, Carls JR, Starbucks, etc. Less than 5 mins from the San Luis Rio Colorado border. 20 min from Yuma & 10 mins from Somerton. Our place is perfect to host comfortably up to 6 people. Short and long stays are welcome.

Superhost
Guesthouse in Somerton
4.78 out of 5 average rating, 315 reviews

Full Studio In a Ranch

Enjoy your stay in a quiet and peaceful Studio in the Counties/outskirts of Yuma and Somerton . You will see my Rottweiler Dog in the backyard as well listen to the roosters sing in the morning. You can walk around the block peacefully. Enjoy your fully fenced private yard area

Guest favorite
Home in San Luis
4.78 out of 5 average rating, 9 reviews

Desert Escape-Minutes From MX Border

Welcome to Desert Escape! Enjoy a quiet and relaxing stay in the heart of San Luis. Whether you’re visiting for work or leisure, this comfortable retreat is close to everything while giving you the peace and quiet you deserve 🌵

Popular amenities for San Luis vacation rentals

When is the best time to visit San Luis?

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Avg. priceG$17,769 GYDG$17,769 GYDG$17,351 GYDG$15,470 GYDG$16,306 GYDG$16,306 GYDG$16,724 GYDG$16,724 GYDG$16,933 GYDG$16,306 GYDG$16,724 GYDG$17,560 GYD
Avg. temp13°C15°C18°C21°C25°C30°C34°C34°C30°C24°C17°C12°C

Frequently Asked Questions

  • Are there family-friendly vacation rentals in San Luis?

    San Luis has more than 120 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in house rentals in San Luis?

    Experience the best of San Luis with our house rentals, starting at about $20 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in San Luis?

    Four-legged friends are welcome in San Luis. Choose from more than 70 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in San Luis?

    Yes! Work meets play with ease at over 90 vacation rentals in San Luis featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there San Luis vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 10 vacation homes with pools in San Luis, available on Airbnb. Make a splash and soak up the sun in style!

  • Where should I stay in San Luis?

    Make yourself at home in San Luis by choosing from our most frequently booked neighborhoods. We have over 190 vacation rentals in Comercial, over 190 vacation rentals in Frontera Estates, and over 190 vacation rentals in Parque Industrial.

  • Do house rentals in San Luis have air conditioning?

    Absolutely! We offer over 100 house rentals with air conditioning in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have a kitchen?

    Absolutely! We offer over 100 house rentals with a kitchen in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have wifi?

    Absolutely! We offer over 100 house rentals with wifi in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have free parking?

    Absolutely! We offer over 100 house rentals with free parking in San Luis. Enjoy a tailored experience with all the comforts you desire.

Quick stats about vacation rentals in San Luis

  • Total vacation rentals

    Explore 190 vacation rentals in San Luis

  • Verified guest reviews

    Over 4,870 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 70 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Wi-Fi availability

    190 of San Luis vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis rentals

  • 4.8 Average rating

    San Luis stays are highly rated by guests—averaging 4.8 out of 5!

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