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Vacation rentals in San Lorenzo District

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Top-rated vacation rentals in San Lorenzo District

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Top guest favorite
An aerial view of a contemporary villa features a spacious pool surrounded by lounge chairs and a seating area. The open-concept design includes large glass doors that invite natural light into the interior spaces. Lush greenery surrounds the property, enhancing its secluded setting.
Villa in Boca Chica
5 out of 5 average rating, 23 reviews

On the Beach Villa in Boca Chica!

Contemporary on the beach Villa with 180° Panoramic Ocean & island views of the Gulf of Chiriqui National Park. Open concept, indoor/outdoor living with private pool & spacious terraces for lounging, sunsets & stargazing. Perched on a cliff with direct beach access. Ocean breezes, tropical birds, exotic monkeys, iguanas & dolphins in the Bay. Private gated community. Large sand beach, perfect for swimming, boogie boarding, long walks, bocce ball or just relaxing & enjoying the sounds of nature.

Top guest favorite
A spacious living area features a comfortable sofa and two accent chairs surrounding a striped area rug. Floor-to-ceiling windows offer panoramic views of the ocean and surrounding islands, while a flat-screen TV is positioned on a low console for easy viewing.
Villa in Boca Chica
4.96 out of 5 average rating, 102 reviews

Sand Dollar Villa by the sea at Boca Chica Panama

Sand Dollar Villa by the sea This beautiful, very private retreat boasts panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach. Sand Dollar Villa offers the perfect décor for gracious living and entertaining in a magical setting!

Top guest favorite
A private outdoor area features a pool surrounded by stone tiles and a covered seating area. Sun loungers are positioned under an umbrella, with views of green landscape and water in the background. The setting provides a serene atmosphere for relaxation.
Home in Playa Hermosa
5 out of 5 average rating, 43 reviews

Entire house with private pool facing beach !

Astonishing views, bird sounds & howler monkeys, Our region is designated by Panama as a Natural Water Preserve with 23 islands, lots of snorkeling, whale watching and beachcombing! One of the top best sport fishing destinations in the world! Casa Tanamera has a large garden set amidst the jungle. it boasts a plunging view on the beach and its entire bay area. the house is large enough for 4 persons, has large bedrooms and bathroom, a large patio with its dining, BBQ and lounge area.

Top guest favorite
A serene pool area features a clear blue pool surrounded by tiled landscaping. Two white lounge chairs and a small table are positioned by the poolside, offering a relaxing spot. Lush greenery and a residential building are visible in the background under a bright blue sky.
Guesthouse in David
5 out of 5 average rating, 72 reviews

Pool House with Shared Pool Access

Pool House is a fully private space on a shared gated property. NOTE: We, the owners of the property, live in the Main House full time. If you have questions/need recommendations, we are available! Shared spaces on property: Pool, front yard, back walk way Local suburb, with bus and taxi access into town and plenty of parking if you choose to drive. 45 minutes from Boquete, 1 hour from Boca Chica and 2 hours and 1 hour boat ride to Bocas Del Toro, this location is a day-tripper's dream!

Superhost
A pathway flanked by vibrant tropical plants leads to an entrance. The wooden walkway is bordered by low greenery and lit by soft, glowing lights. The landscape reflects a serene outdoor environment, complemented by clear blue skies above.
Tiny home in Alto Boquete
4.81 out of 5 average rating, 168 reviews

10 min to Boquete I Cabaña Rio Vista 2-Free coffee

🌿 New Cabin in Boquete – Nature and Spectacular Views • 🌊 Direct access to a beautiful natural river • 🌄 Access to viewpoints with stunning panoramic views •• 🍳 Electric stove (no oven) and coffee maker • 🌬️ Cool mountain climate • 📍 2 minutes from the David-Boquete road • 🐶 Maximum 2 small dogs allowed • 🚗 Last stretch of stone (small car passes without problem) • 🫒 Complimentary coffee, sugar, salt, pepper, cream, and olive oil • 🕒 Check-in 3 pm | 🕛 Check-out 12 noon

Top guest favorite
A spacious room is visible through an open door, featuring a double bed with clean linens and a simple design. Natural light illuminates the area. A handcrafted wooden bench is placed in front of the bed. A potted palm adds a touch of greenery to the setting.
Guest suite in David
4.97 out of 5 average rating, 504 reviews

CasaMonèt

Suite with separate entrance: covered parking, double bed, bathroom, kitchenette and desk. Your personal space in the heart of David. It has split air conditioning, a ceiling fan, a TV with Netflix access, free WiFi internet, blackout curtains, a water reserve tank, hot water, a kitchenette equipped with an electric stove, a refrigerator, a coffee maker, a microwave, and basic utensils. It does not have a laundry room, electric generator, or soundproofing.

Guest favorite
A modern sleeping area features a spacious bed with a dark headboard and a white bedspread. Large windows allow natural light to fill the room, providing a view of the surrounding greenery. A glass table and two chairs are positioned beside the bed.
Apartment in David
4.92 out of 5 average rating, 37 reviews

Escape with a panoramic view

Welcome to Escape with panoramic views, a modern and cozy apartment in Santa Cruz Tower, David. Enjoy a spectacular view from the balcony, queen size bed, air conditioning, desk, Wi-Fi, private bathroom and hot water. Located in a quiet area, but minutes from shopping malls such as Federal Mall and Plaza Terronal, restaurants, supermarkets and businesses. It also has direct access to Boquete, Chiriquí's most popular mountain destination. English or Spanish!

Guest favorite
A small cottage is nestled among trees, featuring a simple white exterior and dark wood window shutters. Softly glowing string lights enhance the entryway, illuminating the path leading inside. The peaceful surroundings contribute to a calm ambiance, inviting relaxation.
Tiny home in Boquete
4.95 out of 5 average rating, 115 reviews

Cozy Sunrise Cottage

Very cozy small cottage but spacious tucked between the trees and only 7 minutes ride to downtown Boquete. The cottage has a washer and dryer and very nice finishes. A comfortable king size bed and kitchenette with all the utensils needed to prepare breakfast or a small meal. Public service transportation is available just as you open the gate and leave the premises. Wi-Fi service available and reliable. Hot water on the shower, sink and kitchen faucets.

Top guest favorite
A peaceful entrance is shown, framed by a landscaped garden. Soft lighting illuminates the pathway and steps leading to a welcoming door. Rolling hills can be seen in the background, complemented by a misty ambiance. The structure features large windows that enhance natural light.
Cabin in Alto Boquete
4.97 out of 5 average rating, 63 reviews

Ave Fénix, spacious, cozy, incredible views!

Keep it simple at this peaceful and centrally-located place. Designed for comfort, a "Murphy" queen bed, the possibility of an extendable leg table to work on. It can be taken outside to enjoy al fresco dining. About 200 meters from transportation, or walk 2 km to downtown. Steps away from a supermarket, service station, gourmet market, cafeteria, restaurants, and a bakery. It has Optic Fiber Internet and Wi-Fi, a TV, and a parking space outside.

Top guest favorite
A modern studio apartment features a well-appointed sleeping area with a spacious bed. A sleek television stands on a minimalist media unit. Large glass doors open to a private balcony, allowing natural light to fill the room. Contemporary furnishings are complemented by marble flooring.
Apartment in David
5 out of 5 average rating, 17 reviews

Fully equipped studio

Modern Studio with Kitchen and Laundry Enjoy this cozy, fully equipped studio. It features a full kitchen with a blender, toaster, coffee maker, utensils, and a washer and dryer for added convenience. The queen bed and sofa provide a comfortable space to rest. The bathroom is spacious and modern. Ideal for short or long stays, in an excellent location. Perfect for those looking for comfort and functionality. Book now and feel at home!

Top guest favorite
A spacious bed is centered in a room with vibrant green walls. Decorative pillows are arranged neatly on the gray bedding, complemented by a bedside table with a lamp. Art featuring a flower and a hummingbird adorns the wall above the bed.
Bungalow in Boca Chica
4.94 out of 5 average rating, 77 reviews

Finca Colibri

A modern bungalow with unique views of the mangroves of Bajia de Muerte Bay, located in the heart of a nature reserve. The bungalow is very private and quiet. It's just a few minutes drive to the nearest beach. You can expect a fully equipped kitchen, a modern furnished panoramic bathroom and a very comfortable king size bed. By request we can also organize boat trips to the islands, yoga as well as horseback riding and fishing trips.

Guest favorite
The property features a spacious beachfront villa, framed by lush palm trees and open grass areas. A vibrant red roof contrasts with the white exterior, and the shimmering ocean is visible in the background, providing a serene coastal atmosphere.
Home in Playa Nanzal
4.91 out of 5 average rating, 34 reviews

Private Beachfront Getaway

Forget your worries in this spacious and serene space. Its seclusion is its charm. Escape from the busy city of David and kick back in our private beachfront property! There are little to no lights nearby, making for extraordinary sunsets/sunrises and star gazing. Whether you are a family looking to get away in the summer, a group of friends celebrating a birthday, or just looking for a break from life, this is the spot.

Popular amenities for San Lorenzo District vacation rentals