Vacation rentals in San Lorenzo District

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Top-rated vacation rentals in San Lorenzo District

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A spacious living area features a comfortable sofa and two accent chairs surrounding a striped area rug. Floor-to-ceiling windows offer panoramic views of the ocean and surrounding islands, while a flat-screen TV is positioned on a low console for easy viewing.

Villa in Boca Chica

Sand Dollar Villa by the sea at Boca Chica Panama

Sand Dollar Villa by the sea This beautiful, very private retreat boasts panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach. Sand Dollar Villa offers the perfect décor for gracious living and entertaining in a magical setting!

ValueLocationBeach

4.95 out of 5 average rating, 111 reviews

Top guest favorite

Apartment in David

Amplio balcón | 2 hab. en el corazón de David

Disfruta David desde un moderno apartamento de 2 hab., pensado para ejecutivos y familias. Empieza el día con un café en su amplio balcón, relájate con una película en la acogedora sala o simplemente una caminata a conocer la ciudad. Con una ubicación estratégica a 2 min en auto de la vía Interamericana y Plaza Terronal y a 5 min de Federal Mall. Cerca de restaurantes, plazas y comercios, con fácil conexión hacia Boquete, Cerro Punta, la frontera con Costa Rica y otros destinos de Chiriquí.

LocationGetting aroundCondition

5.0 out of 5 average rating, 5 reviews

Top guest favorite

A private outdoor area features a pool surrounded by stone tiles and a covered seating area. Sun loungers are positioned under an umbrella, with views of green landscape and water in the background. The setting provides a serene atmosphere for relaxation.

Home in Playa Hermosa

Entire house with private pool facing beach !

Astonishing views, bird sounds & howler monkeys, Our region is designated by Panama as a Natural Water Preserve with 23 islands, lots of snorkeling, whale watching and beachcombing! One of the top best sport fishing destinations in the world! Casa Tanamera has a large garden set amidst the jungle. it boasts a plunging view on the beach and its entire bay area. the house is large enough for 4 persons, has large bedrooms and bathroom, a large patio with its dining, BBQ and lounge area.

LocationFamilyLaundry

5.0 out of 5 average rating, 52 reviews

Top guest favorite

A spacious room is visible through an open door, featuring a double bed with clean linens and a simple design. Natural light illuminates the area. A handcrafted wooden bench is placed in front of the bed. A potted palm adds a touch of greenery to the setting.

Guest suite in David

CasaMonèt

Suite con entrada independiente: estacionamiento techado, cama doble, baño sanitario, cocineta y escritorio. Tu espacio personal en el corazón de David. Cuenta con aire acondicionado tipo split, abanico de techo, TV con acceso a netflix, internet wifi gratis, cortinas black out, tanque de reserva de agua, agua caliente, cocineta equipada con estufa eléctrica, refrigerador, cafetera, microondas y utensilios básicos. No cuenta con lavandería, generador eléctrico y aislamiento acústico.

FamilyValueSolo travel

4.97 out of 5 average rating, 567 reviews

Guest favorite

Home in Boca Chica

Escape to your oceanfront retreat: Sea La Vie!

This stunning new home, offers a 2-bedroom, 2.5-bath main house and a separate studio casita, hosting up to six guests. Enjoy open living spaces, a gourmet kitchen, and panoramic ocean views. Solar-powered and nearly off-grid, with Starlink Wi-Fi for modern comfort. Surrounded by wildlife and waves, it’s a peaceful sanctuary where luxury meets nature.Wake to howler monkeys calling at dawn and fall asleep to the symphony of tree frogs and gentle surf. Your forever paradise in Playa Hermosa.

FamilyLocationIndoor spaces

4.85 out of 5 average rating, 13 reviews

Top guest favorite

Home in Los Algarrobos

Acogedora y relajante casa con terraza

Relájate con toda la familia en este tranquilo lugar, a solo 10 minutos del centro de David y 25 minutos del turístico Boquete. Muy cerca encontrarás centros comerciales, restaurantes y servicios, pero lo suficientemente alejado del bullicio de la ciudad. Un espacio seguro, cómodo y lleno de detalles para que disfrutes tu estadía. Casa segura con 3 recámaras, terraza estilo Café-Bar, patio con asador y gazebo, aires acondicionados y todas las comodidades para disfrutar tu estadía.

FamilyValueAir conditioning

4.95 out of 5 average rating, 184 reviews

Guest favorite

Home in David

Casa moderna vía aeropuerto

Descubre este alojamiento sofisticado y acogedor, ideal para viajeros que buscan comodidad y tranquilidad. Esta casa moderna cuenta con tres amplias habitaciones y dos baños, perfectos para garantizar privacidad y comodidad. Ubicada en una zona estratégica, estarás a solo minutos del aeropuerto y del centro de la ciudad, combinando conveniencia y tranquilidad en un solo lugar. Esta casa es el refugio perfecto que combina estilo, funcionalidad y comodidad. ¡Te esperamos!

LocationFamilyCondition

4.88 out of 5 average rating, 76 reviews

Top guest favorite

A spacious bed is centered in a room with vibrant green walls. Decorative pillows are arranged neatly on the gray bedding, complemented by a bedside table with a lamp. Art featuring a flower and a hummingbird adorns the wall above the bed.

Bungalow in Boca Chica

Finca Colibri

Ein moderner Bungalow mit einmaligen Blick auf die Mangroven von der Bucht Bajia de Muerte, die im Herzen eines Naturschutzgebietes liegt. Der Bungalow ist sehr privat und ruhig gelegen. Zum nächsten Strand sind es nur wenige Autominuten. Es erwarten dich eine voll ausgestattete Küche, ein modern eingerichtestes Panorama Bad und ein sehr bequemes King Size Bett. Auf Anfrage können wir auch Bootsfahrten zu den Inseln, Yoga sowie Reit und Angelausflüge organisieren.

LocationValueDecor

4.94 out of 5 average rating, 84 reviews

Guest favorite

A round wooden dining table is set for four, surrounded by light-colored chairs. A chandelier hangs above, casting a warm glow. Light enters through open doors, highlighting wall art and plants, creating a welcoming dining space.

Casa particular in Dolega District

Wanakaset Forest Haven 2BR, River & shared Pool

(Minimum 2 nights) Casa Quetzal is a serene 2-bedroom retreat nestled in the lush forest of Wanakaset Panama, perfect for up to 4 guests. With its open-plan living space, modern bathrooms, and fully equipped kitchen, it offers comfort in a natural setting. Relax on the private terrace or enjoy the shared pool, just a short walk away. Surrounded by rivers and tropical greenery, it’s an ideal escape for nature lovers seeking tranquility and a peaceful getaway.

LocationOutdoor spacesCleanliness

5.0 out of 5 average rating, 8 reviews

Superhost

The property features a spacious beachfront villa, framed by lush palm trees and open grass areas. A vibrant red roof contrasts with the white exterior, and the shimmering ocean is visible in the background, providing a serene coastal atmosphere.

Home in Playa Nanzal

Private Beachfront Getaway

Forget your worries in this spacious and serene space. Its seclusion is its charm. Escape from the busy city of David and kick back in our private beachfront property! There are little to no lights nearby, making for extraordinary sunsets/sunrises and star gazing. Whether you are a family looking to get away in the summer, a group of friends celebrating a birthday, or just looking for a break from life, this is the spot.

FamilyValueWifi

4.86 out of 5 average rating, 57 reviews

Top guest favorite

Home in Boca Chica

beach house: Villa Pacifica

Villa Pacifica, by far your best choice on the Pacific Ocean. constructed this year, at 30 mt from the private beach of our farm Punta Vittoria in Boca Brava island. Your own beachbar, boat dock, situated in our valley, guaranteeing your total privacy. 3 bedrooms/bath,totally equipped kitchen, large terrace, AC, fresh water pool,and elegantly decorated. A unique blend of nature, wildlife and ocean living.

FamilyLocationComfort

5.0 out of 5 average rating, 6 reviews

Top guest favorite

A functional kitchen area is equipped with wooden cabinets and a countertop. Natural light enters through large windows adorned with sheer curtains, highlighting modern appliances including a stove, coffee maker, and refrigerator. The tiled floor complements the warm wooden tones.

Bungalow in Las Lajas

Guesthouse Buena Vista

Unser Gästehaus liegt am Rande des Dörfchens Las Lajas, umgeben von einem tropischen Garten mit Blick auf die umliegenden Berge. Alle notwendigen Einrichtungen wie Supermarkt, Restaurants, Eisdiele etc. sind fußläufig zu erreichen. Las Lajas ist nicht nur bekannt für seinen langen Sandstrand, sondern dient auch als Ausgangspunkt für viele touristischen Aktivitäten und Touren. Sprechen Sie uns darauf an!

ValueLocationBeach

4.97 out of 5 average rating, 30 reviews