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Guesthouse vacation rentals in San Diego Bay

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in San Diego Bay

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A curving staircase is visible, flanked by white walls and adorned with vibrant blue tiles. Handrails provide support along the ascent, leading to a bright upper space. A potted plant enhances the serene ambiance at the top of the stairs.
Guesthouse in San Diego
5 out of 5 average rating, 238 reviews

Santorini-Inspired Cottage w/ Hot Tub + Views

*CHECK OUT OUR OTHER AIRBNB* Travel 16 steps up a Greek-inspired curving stairway with 2-story high walls to your tucked-away cottage built into the hillside villa of Alta Colina.  With spectacular views, step onto the balcony to watch planes take off & boats sail around the harbor. End the night in front of your secluded back patio fireplace or climb the steps of your spiral staircase to the rooftop Jacuzzi. European-inspired design & details, it'll be hard to believe you’re still in San Diego!

Top guest favorite
A private garden is illuminated at night, featuring various seating areas surrounded by lush greenery and colorful plants. Lanterns provide soft light, casting a warm glow on the outdoor space. A patterned rug and dark wooden furniture complete the serene atmosphere, inviting relaxation.
Guesthouse in San Diego
4.96 out of 5 average rating, 563 reviews

Romantic Private Garden Studio Near Downtown

A magical private garden surrounds a tiny studio (240 sq ft) with kitchenette in historic residential district, 10 blocks to East Village and Petco BallPark, near Gaslamp Quarter, and one mile to Convention Center and downtown. Easy access to freeways, very close to Balboa Park, San Diego Zoo, and Coronado Island. Airport and train station less than 15 min. We offer a safe, sweet, and contemplative getaway near the city, with WiFi but no TV. One pet OK only with prior approval. 420 friendly.

Top guest favorite
A private patio space surrounded by lush greenery features seating areas with wooden chairs and potted plants. Soft lighting is provided by outdoor string lights, and a cozy rug adds warmth. In the distance, a shaded area with an umbrella can be seen, enhancing the tranquil setting.
Guesthouse in San Diego
4.96 out of 5 average rating, 262 reviews

Sunny garden casita in vibrant North Park

Enjoy peaceful, sunny San Diego days as palms sway above this private garden retreat tucked behind a 1925 Craftsman. Designed with a love of nature and simple beauty, the guest house opens onto lush greenery and dappled light — a calm, creative hideaway in the heart of one of San Diego’s most charming neighborhoods. Just a short stroll brings you to great restaurants, world-class breweries, and cozy coffee shops, while Balboa Park, the Zoo, the beaches, and downtown are all only minutes away.

Top guest favorite
A cozy studio space features a spacious bed with patterned bedding, complemented by warm orange and neutral tones on the walls. A small dining area with two chairs and a table is visible, along with a kitchenette and a bathroom entrance in the background.
Guesthouse in San Diego
4.93 out of 5 average rating, 534 reviews

Private Cottage in Walkable North Park w/AC

Welcome to our charming private Airbnb in vibrant North Park! Enjoy the perfect blend of comfort and convenience for your San Diego stay. Walk to restaurants, coffee shops, art galleries, wine bars, breweries, yoga studios & various boutiques. Nature lovers will adore the nearby Balboa Park with its stunning gardens and cultural attractions. Downtown, Gaslamp Quarter, beaches, and the famous San Diego Zoo are easily accessible. Book and create lasting memories in this dynamic neighborhood.

Top guest favorite
A spacious living area features a large sectional sofa adorned with decorative pillows, complemented by a wooden coffee table. A vibrant wall art piece with colorful surfboards is displayed above the couch, while natural light fills the room through expansive windows.
Guesthouse in San Diego
4.97 out of 5 average rating, 275 reviews

Beautiful Historic Home and Gardens Near Downtown!

Location, Location, Location...Welcome to Union Street Gardens. We are dedicated to providing a peaceful, serene atmosphere in which our guests can relax after a long day of exploring beautiful, sunny San Diego. This unique historic craftsman bungalow is just minutes from downtown, Balboa Park, the Zoo, beaches, and includes a Chef's kitchen, outdoor deck, gardens, fire pit and spa! Perfect for a family of 4 or two couples. Sorry no parties or large groups and no external guests please.

Superhost
A covered patio features a table and four chairs, providing a shaded space for relaxation. Lush greenery is visible in the background, and a serene sunset glow illuminates the area, enhancing the tranquil atmosphere.
Guesthouse in San Diego
4.94 out of 5 average rating, 101 reviews

Secluded Guesthouse in Central San Diego

Very private guesthouse w/ full kitchen and bathroom. Quiet space perfect for anyone who wants to work or relax in the heart of San Diego. Plenty of FREE on-street parking. Location ⁃ 5 min to 94 and 805 freeways ⁃ 10 min from Downtown ⁃ 15 min from beaches and SeaWorld ⁃ 10 min walk to trolley ⁃ Restaurants/supermarkets within walking distance Amenities ⁃ Brand new mini-splits ⁃ Smart TV w/ Roku (BYOP) ⁃ Queen bed - Tempur-Pedic ⁃ Full kitchen ⁃ Air purifier ⁃ Free on-site laundry

Guest favorite
A light-filled studio apartment is presented, featuring a dining table with two chairs and a kitchenette equipped with modern appliances. The space boasts a ceiling fan and large mirror, while a bathroom area is visible with a blue rug. Neutral-toned walls create a clean atmosphere.
Guesthouse in San Diego
4.87 out of 5 average rating, 1,073 reviews

Private Garden Studio

Enter through a hidden garden filled with plants into a cute, clean, recently refurbished studio apartment. Although the house sits on a quiet street with abundant free street parking, it is within easy walking distance of craft breweries, cocktail bars, cafes, and some of San Diego's best restaurants, as well as Trolley Barn Park. We're also an easy shot to the zoo, Balboa Park museums, downtown, and the beaches.

Top guest favorite
Guesthouse in San Diego
4.86 out of 5 average rating, 321 reviews

Frida House - Cozy cottage minutes from downtown

Welcome to your secret hideaway in San Diego! The Frida House has a private entrance so you can easily come and go and is located in quiet, family-oriented neighborhood in the Sherman Heights historic district just a few blocks from downtown San Diego. The Frida House is just minutes away from the convention center, Petco Park, the Gaslamp District, the Coronado bridge, Balboa Park, and the San Diego Zoo.

Guest favorite
A living area features a cozy orange sofa adorned with colorful pillows. A desk with a green chair is situated near a window covered with vertical blinds, allowing natural light to illuminate the space. An air conditioning unit is mounted on the wall.
Guesthouse in San Diego
4.95 out of 5 average rating, 129 reviews

*KING BED* Colorful Guesthouse by Downtown

Welcome to Emerald Guesthouse, built in 2014, located just 4.3 miles from downtown SD and close to many major freeways. This family friendly guesthouse is part of a 2-unit building with its own private entrance, with one bedroom and one bathroom, full kitchen, laundry, 2 rollaway beds with memory foam mattress, provides you with all the amenities you need for a wonderful stay.

Guest favorite
A spacious studio room features warm wooden walls and contemporary furnishings. A queen-sized bed is accompanied by accent pillows. Large double doors open to a private deck with garden views, while a work desk and chair are positioned near the entrance.
Guesthouse in San Diego
4.9 out of 5 average rating, 1,165 reviews

Safe Hip Quiet GARDEN STUDIO / Northpark

Come to a quiet and stylish studio to relax. Check-in contactless and enjoy! Cozy, hip and private garden studio with private entrance, private full bathroom, and private deck. The Studio house is in a large garden adjoining a craftsman-style house in the historic Northpark/ Morley Field District. Minutes away from coffee shops, breweries, Zoo, Balboa Park.

Top guest favorite
A spacious bedroom features a king bed with neutral bedding and decorative pillows. French doors provide natural light and open to a balcony overlooking lush greenery. A modern ceiling fan and soft lighting complement the hardwood floor and simple decor, creating a comfortable and inviting space.
Guesthouse in San Diego
4.97 out of 5 average rating, 203 reviews

New Guest House - North Park

One bedroom detached guest house with central air in one of the most desirable locations in North Park / South Park. Extremely walkable and safe location near numerous restaurants, breweries and cafes. Family friendly, we provide a pack n' play and highchair upon request. NO SMOKING OR VAPING ON PROPERTY

Superhost
The kitchenette features wooden cabinets and a modern gas stove. A countertop with a coffee maker and sink is visible, along with a decorative rug on the floor. An adjacent laundry unit is integrated into the space, providing convenience for guests.
Guesthouse in San Diego
4.84 out of 5 average rating, 118 reviews

PRIVATE VISTA SUITE/ CENTRAL SAN DIEGO 1BED/1BATH

-Cozy comfortable Guest Quarters -Private entrance - Located on quite street. -Easy fast freeway access -Central to everything - Parking - Wi-Fi, Smart TV - Laundry - Minutes to shopping - Minutes to tons of great restaurants -Absolutely no smoking, drugs or pets on the property.

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