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Vacation rentals in Saint Charles

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Top-rated vacation rentals in Saint Charles

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A spacious living area features a comfortable brown couch centered around a coffee table. A rustic fireplace is set against a brick wall, providing warmth. Light-colored walls and plenty of windows enhance the natural light flowing into the room.
Home in St. Peters
4.88 out of 5 average rating, 396 reviews

Private Walkout w King Bed & Bath + large livingrm

Our house sits in a very quiet and safe neighborhood. When you stay with us you will enter through the walkout basement. You have full access to our very private downstairs apartment. This will enter you right into the very large living area. The master bedroom is complete with a King bed, black out curtains and walk-in closet. Attached is a full size bathroom with walk-in shower. Amenities include television, DVD, WiFi, Kuerig, mini-fridge and access to patio/porch with backyard fire pit.

Top guest favorite
The charming front porch features a white wicker chair and a decorative wreath, inviting relaxation. Greenery surrounds the entryway, complemented by a well-maintained lawn. A gravel pathway leads from the porch to the driveway, creating a welcoming entrance to the guest house.
Home in Saint Charles
4.97 out of 5 average rating, 702 reviews

301 Guesthouse- Historic Main street-Katy Trail

Our 301 Guest House is new and completely remodeled in 2018! It’s ideal for one or two people with beautiful furnishings, great queen bed, lots of amenities, full kitchen, with big back yard and patio to enjoy outdoors too! Cable and FAST WiFi! Enjoy light Breakfast! BEST location, Great events year round within walking distance, with being only about 2 blocks from S. Main St, where there are about 100 gift shops n restaurants! Katy Trail is so close, with Spring, Summer, Fall and Xmas events!

Top guest favorite
The exterior of a rustic log cabin is depicted at night, showcasing weathered wooden walls and large windows. A welcoming porch with a swing is adorned with a decorative red, white, and blue bunting. Lush greenery surrounds the cabin, illuminated gently by outdoor lighting.
Cabin in Saint Charles
4.98 out of 5 average rating, 366 reviews

Camp Mill Pond: Historic Cabin Near Main Street

*St. Louis Magazine A-List Winner!* ***PRESS: DESIGN STL, STL MAG, AND FOX2NEWS*** Camp Mill Pond is a throwback to the slow and easy rhythm of hot summer days. This circa 1835 cabin offers easy access to our historic area, including Main Street, Katy Trail for biking, and Frenchtown, without sacrificing modern comforts! This 180-year-old historic cabin sits on a beautiful lot, shared with our 1865 three-story home and a two-story carriage house. Ask about renting bikes and a golf cart!

Top guest favorite
Home in Saint Charles
4.9 out of 5 average rating, 281 reviews

Tompkins Street Retreat

Relax in this two-bedroom, two-bath house with a backyard patio and firepit with a privacy fence. Walk to unique shopping and entertainment on Historic St. Charles Main Street. Local wineries and St. Louis attractions are a short drive away. Enjoy a comfortable living room with a large TV and a fully equipped kitchen for special meals. Unwind after an active day with a meal, drinks under the pergola, and a great night's sleep in our king-size bed. We also offer FREE off-street/garage parking.

Guest favorite
Apartment in St. Charles Historic District
4.94 out of 5 average rating, 399 reviews

Charming Pop Lucks Guest Suite in Old St. Charles

Welcome to Pop Luck's Guest Suite! This adorable gem represents everything you love about Old St. Charles. This cozy suite is just steps away from the heart of Main Street, restaurants, and all the action St. Charles has to offer. Pop Luck's is a charming one-bedroom, with an open and airy living room and kitchen. It has natural light and high ceilings throughout. It's farmhouse cottage decor makes for a relaxing place to rest. Also, check out our sister suite The Ella Rose, right next door.

Top guest favorite
Home in Saint Charles
4.97 out of 5 average rating, 282 reviews

Sweet Escape Near Historic Main St, 4BR, 2 Baths

Discover your Sweet Escape in this charming 4-bedroom bungalow, just a 3-minute drive (or 20-minute walk) to Historic Main Street’s cobblestone streets, boutique shops, dining, and events. Now featuring two full bathrooms, including a newly added second-floor bath for extra convenience. Enjoy a game-filled basement with pool table, ping-pong, foosball, and darts, plus yard games, a fire pit, and cozy nights with board games and DVDs. Sleep soundly on plush beds with room-darkening curtains.

Guest favorite
A treehouse structure is elevated among snow-covered trees, with wooden steps leading to its entrance. A small porch with festive decorations can be seen, while a second rental unit is adjacent, also elevated. The surrounding woodland offers a serene winter backdrop.
Guest suite in Dardenne Prairie
4.88 out of 5 average rating, 316 reviews

Treehouse Spa Suite

Treehouse Day Spa is nestled on 3 wooded acres in St.Charles County. There is a subdivision next to me but I have my trees!!! Get away from it all while being close to it all at the same time. Augusta wineries, Main Street St. Charles and the Streets of Cottleville are all within minutes of the location! There are two rental units in the treehouse: The spa suite and the penthouse. They each have a separate entrance and are private spaces. Recharge your battery! Regroup Relax Refresh

Guest favorite
The living room showcases a blend of seating options, including a black futon and a brown leather sofa, complemented by a colorful area rug. Natural light filters through patterned curtains, illuminating the space which features a television and decorative touches.
Home in Saint Charles
4.95 out of 5 average rating, 130 reviews

Cozy Mid-Century Modern Townhome

This comfy 2 bedroom, 1.5 bath townhome is perfect for up to 5 guests. Luxury King bed in bedroom 1 and luxury Queen bed in bedroom 2. A futon in the living room can be used for a 5th guest. A pack-n-play is available upon request. This dynamic location is 5 minutes from bars, restaurants, shopping, Lindenwood University, and Ameristar Casino. It's only 2 miles from St. Charles, historic, Main Street, and it's only 15 minutes from the airport, and about 30 minutes from downtown St. Louis.

Top guest favorite
Bungalow in St. Charles Historic District
4.97 out of 5 average rating, 258 reviews

Patio House, secluded in heartbeat of Main Street

The Patio is nestled in the heart of historic St. Charles a few steps from Main Street, Katy Trail, Missouri River, Antique and Boutique Shopping, Restaurants Bars and More, Several Wedding venues are within walking distance of the property as well. In addition to your well appointed unit, this property has as much outside as it does in. Take your coffee, wine, water and enjoy our patio, complete with fire table, dining table edged with lush plantings for privacy. PLEASE NOTE NO SMOKING

Guest favorite
The exterior of a charming century home showcases a covered front porch with white railings and a welcoming entrance. Lush greenery and flower beds line the stone steps leading to the porch, enhancing the inviting character of the property.
Home in Saint Charles
4.94 out of 5 average rating, 392 reviews

*HotTub* The Jewel on 5th-2br2b-near Historic Main

A true gem only a 15 min drive from the STL Airport. Enjoy a well equipped, century home a short 12 min walk to Historic Main and a HOTTUB. The large stocked kitchen is great for entertaining. Master bedroom w/luxurious, king sized, 4 poster bed and ensuite bathroom awaits you. In the private, queen suite you’ll find its own bathroom and another door leading onto the deck. The chair off the kitchen folds out to a standard twin and bedding is provided for the sofa as well. Can sleep 6.

Top guest favorite
A kitchen space features modern appliances including a stainless steel stove and dishwasher. Exposed brick is contrasted by light cabinetry and a butcher block countertop. Windows allow natural light, highlighting the marble-patterned flooring, while a doorway provides access to a separate laundry area.
Home in Saint Charles
4.96 out of 5 average rating, 302 reviews

Bright & Cozy Shotgun DPX 1 Block from Historic DT

Admire this unique historic home's design with brand new amenities and antique details that give a fresh and charming feel. Built in the late 1800's, this half of the duplex has a typical shotgun layout with ten-foot ceilings giving a spacious feel. The front door leads directly to the living room, then into the bedroom, both of which have the original hard wood floors. The back of the house has the kitchen, with exposed brick, a dining area, and a bathroom with a washer and dryer.

Top guest favorite
The entrance of the Rue Royale Condominiums showcases a two-story brick building with large windows. An inviting balcony extends over the entry, supported by a black metal awning. Outdoor seating is available on the patio, complemented by greenery along the entrance.
Condo in Saint Charles
4.94 out of 5 average rating, 171 reviews

Cozy Studio in Beautiful New Town St. Charles

Stay at this cozy studio centrally located in the amazing community of New Town St. Charles. New Town is a large scale new urbanist community built on the edge of suburbia. You never have to leave New Town with its walkability to restaurants, bars, a market, coffee shops, ice cream, food kiosk, canals, lakes, parks and tree lined streets. If you do leave its only a few miles from historic St. Charles Main street, The Streets of St. Charles, and 25 miles to Downtown St. Louis.

Popular amenities for Saint Charles places to stay

When is the best time to visit Saint Charles?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$27,224 GYDG$27,434 GYDG$29,737 GYDG$30,366 GYDG$29,947 GYDG$31,413 GYDG$30,575 GYDG$30,575 GYDG$30,784 GYDG$30,784 GYDG$29,737 GYDG$29,737 GYD
Avg. temp0°C3°C8°C14°C20°C25°C27°C26°C22°C15°C8°C3°C

Frequently Asked Questions

  • What are the best places to stay in Saint Charles?

    Stays in the Historic Main Street district are frequently suggested for their proximity to restaurants, local shops, and riverside walks. The New Town area is also known for its welcoming vibe, unique design, and access to scenic green spaces.

  • What are the best things to do in Saint Charles with kids?

    Explore interactive exhibits at museums, stroll the Katy Trail, or enjoy riverside parks with playgrounds. Family-friendly activities often include hands-on history experiences and seasonal outdoor events tailored for all ages.

  • What are some of the best things to do in Saint Charles?

    Wander along Historic Main Street, discover local history at museums, and enjoy outdoor paths by the Missouri River. Art galleries, unique boutiques, and landmark sites add to the city’s active cultural scene.

  • How is the weather in Saint Charles?

    Saint Charles has cold winters with temperatures around 24–40°F (-5–5°C), and warm, humid summers near 71–90°F (22–32°C). Spring and autumn bring milder temperatures, though sudden rain showers are common throughout the year.

  • What are the best places to visit in Saint Charles?

    Historic Main Street is known for its preserved buildings and local shops, while the Lewis & Clark Boat House and Museum shares stories of regional exploration. Frontier Park by the river is frequently suggested for walks and community events.

  • What are some hiking trails in Saint Charles?

    The Katy Trail invites walkers and cyclists along scenic river views and wooded stretches. Parks around the city also have flatter family-friendly paths and opportunities to spot wildlife.

  • What are some family activities we can do in Saint Charles?

    Families can explore hands-on museum exhibits, relax in local parks, or cruise along the Missouri River on guided tours. Seasonal fairs and interactive history walks are often popular with younger visitors.

  • What are some of the best day trip ideas from Saint Charles?

    Explore historic sites in the surrounding region, visit nearby wineries, or wander regional nature reserves for birdwatching and hiking. Local towns around Saint Charles frequently feature artisan markets and farm experiences.

  • Are there any pet friendly accommodations available in Saint Charles?

    Many stays in Saint Charles welcome pets, especially around New Town and near local parks. Riverside walking paths and several outdoor dining spots make it easy to include your pet in city explorations.

  • What are some local tips for visiting Saint Charles?

    Wearing comfortable shoes is helpful for exploring the brick sidewalks of Historic Main Street. Frequent local events and open-air markets can get lively, and many shops are housed in historic buildings with unique features.

  • What is Saint Charles known for?

    Saint Charles is known for its preserved historic district, roots tied to early westward exploration, and vibrant Main Street culture. The city has long been a gathering place for festivals, artisan markets, and riverfront activities.

  • What are the best hidden gems to explore in Saint Charles?

    Quiet corners of Frenchtown around unique antique shops and the Foundry Art Centre’s changing exhibits are often highlighted as hidden gems. Locally loved bakeries and off-the-beaten-path parks also invite exploration.

  • What are the best foods to try in Saint Charles?

    Locally rooted dishes include toasted ravioli, barbecued meats, and German-inspired fare reflecting the area’s heritage. Bakeries and sweet shops along Main Street are also frequently suggested for desserts and pastries.

  • What should I bring for a trip to Saint Charles?

    Pack layers to adjust to changing temperatures, along with comfortable shoes for walking historic areas and local trails. An umbrella or light rain jacket is useful year-round due to potential sudden showers.

  • What is the nightlife in Saint Charles like?

    Saint Charles has a mix of laid-back taverns, live music venues, and pubs, many located in the historic district. Enjoy casual spots for conversation or explore community events and occasional performances downtown.

  • What are the most popular events or festivals in Saint Charles?

    Seasonal festivals along Historic Main Street often celebrate heritage, music, and regional food, while riverfront spaces host fireworks displays around national holidays. Christmas Traditions, held in late autumn and winter, is frequently suggested for its festive character.

  • Are there family friendly vacation rentals in Saint Charles?

    Family-friendly rentals can be found in several neighborhoods, especially near parks or the Main Street area, with options like multi-bedroom homes and spacious apartments. Many hosts provide amenities designed to support kids and group stays.

  • When is the best time to visit Saint Charles?

    Late spring through early autumn is often recommended for milder weather and frequent local festivals. Autumn’s changing leaves and spring’s blooming flowers both add vibrant character to the city.

Quick stats about vacation rentals in Saint Charles

  • Total vacation rentals

    Explore 210 vacation rentals in Saint Charles

  • Nightly prices starting at

    Saint Charles vacation rentals start at G$4,188 GYD per night before taxes and fees

  • Verified guest reviews

    Over 17,130 verified reviews to help you choose

  • Family-friendly vacation rentals

    140 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 90 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    140 properties have a dedicated workspace

  • Wi-Fi availability

    210 of Saint Charles vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Free parking on premises, Gym, and BBQ grill across Saint Charles rentals

  • 4.9 Average rating

    Saint Charles stays are highly rated by guests—averaging 4.9 out of 5!

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