Apartment vacation rentals in Saint Charles

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Popular amenities for Saint Charles apartment rentals

Weekly apartment rentals

Guest favorite
Apartment in Downtown East St. Louis
5 out of 5 average rating, 11 reviews

Stay Downtown: Walk to Arch, Busch & Casino!

ShaiRating, 5 stars1 week ago
Thank you for making my stay so enjoyable and for providing detailed instructions for check-in and parking. The location was perfect—just the right distance from the America Center. I plan to return in 2026 and will be recommending this spot to the other couples who will be coming as well.
Guest favorite
Apartment in St. Louis
4.92 out of 5 average rating, 84 reviews

5-Star Suite | Central Location ~5 mins to DT STL

RoshonRating, 5 stars1 month ago
The location was exactly as described in photos , very clean , cozy , & quiet and walkable to most amenities needed . If given the opportunity i would definitely stay here again
Superhost
Apartment in Tower Grove South
4.76 out of 5 average rating, 78 reviews

Stylish Studio in North Hampton Neighborhood

CandiceRating, 5 stars1 week ago
Wonderful stay! Adam is a great host!! We will be back!
Top guest favorite
Apartment in St. Louis
4.95 out of 5 average rating, 97 reviews

SALE! Charming Kirkwood (2) Bedroom

HeatherRating, 5 stars1 week ago
The place was perfect. It was a respite from work and made my time for an extended work trip really comfortable. Haedyn is an excellent host in the place is great.
Superhost
Apartment in Overland
5 out of 5 average rating, 5 reviews

Tiny Home Style Studio Apartment mins to Airport

VenetaRating, 5 stars6 days ago
Great spot, the tucked away parking space behind the house was perfect for our super packed car as we were on a cross country road trip and were nervous about parking it in an exposed area. Everything was clean and as advertised, though you should make sure to bring own toiletries and hand soap. 100% would recommend
Top guest favorite
Apartment in Midtown
5 out of 5 average rating, 99 reviews

Large Boho Loft in Art District

ChuckRating, 5 stars1 month ago
Clean, thoughtfully decorated, Nice quality to the amenities, including things like soaps, towels, range kitchen supplies. Needed help from from Tori. a couple of times. She was responsive, pleasant, helpful.
Superhost
Apartment in University City
4.75 out of 5 average rating, 63 reviews

#2 Lower Level Efficiency w Climate Control

RyanRating, 5 stars3 weeks ago
Great value in a great neighborhood. Would absolutely come back and stay again. Excellent communicator with clear instructions. Clean comfy and cozy basement apartment in a great area.
Top guest favorite
Apartment in St. Louis
4.97 out of 5 average rating, 35 reviews

Garden Terrace Apartment

JanetRating, 5 stars1 month ago
Shane’s apartment was clean, comfy and quiet. I had a bit of trouble accessing the apartment on arrival (because I’m technically challenged) but Shane was quick to respond. I very much enjoyed my stay there…..especially the peaceful back porch.

Private apartment rentals

Guest favorite
Apartment in Tower Grove South
5 out of 5 average rating, 9 reviews

Classic TG Park Apartment

IsabelRating, 5 stars2 weeks ago
We had a wonderful stay in St Louis. The apartment was clean and peaceful. Steven went above and beyond to make sure our stay was comfortable. We look forward to coming back!
Guest favorite
Apartment in Soulard
4.95 out of 5 average rating, 64 reviews

*SAFE Soulard 1bd1bth APT / 5 mins frm Dwntwn STL*

LeslieRating, 5 stars2 days ago
We enjoyed Logan’s place.. very clean..and modern. Logan always answered very quickly to our questions. I would highly recommend!
Guest favorite
Apartment in Kirkwood
4.93 out of 5 average rating, 29 reviews

Summer Sale! Cozy Kirkwood (2) Bedroom

MakenzieRating, 5 stars2 days ago
Debbie’s place was stunning!! 🤩 the apartment felt very big and welcoming. The bed was very comfy. The towels in the bathroom were nice and thick like the ones we have back home. I have found a lot of air bnbs cheap out and go with a thin, small towel but not these ones! Kitchen table was great for dining and fridge and freezer were good for groceries. We will be back next year for our annual trip!!
Guest favorite
Apartment in St. Louis
4.96 out of 5 average rating, 67 reviews

1N Gorgeous 1 Bedroom Dogtown, A Sunlit Sanctuary

LucindaRating, 5 stars2 weeks ago
We had a lovely stay at Davis’ apartment! He was communicative and helpful throughout the entire stay, even providing some local recommendations.
Guest favorite
Apartment in The Hill
4.92 out of 5 average rating, 71 reviews

Bella Nido

HayleyRating, 5 stars2 days ago
Loved this little gem on The Hill! Francisco’s place was exactly what we needed and in the midst of so many restaurants/shops and there is the cutest little coffee shop directly across the street which was a nice bonus. If we come back to the area, we will definitely stay again.
Top guest favorite
Apartment in Downtown East St. Louis
5 out of 5 average rating, 37 reviews

Arch View from private deck, 2 BR 2 BA sleeps 6

CynthiaRating, 5 stars4 days ago
We enjoyed our stay in the 3rd level apartment. It was clean and perfectly laid out ti give everyone a space when needed. The historic building has been renovated while preserving the beautiful brick and wood of the time period but also including modern day conveniences. We attended a concert at the Dome and had no issues walking to and from the venue. I mean it was amazing being able to find the solitude of the space after. Despite being right in the downtown area the space was still quiet. Beds were comfortable and plenty of towels were made available. Check out was so easy. Victor’s communication was 5 Star! From the moment of booking, to accommodating a last minute early check-in request to our last day check out reminder. If we are ever in St. Louis for any reason we would stay here.
Guest favorite
Apartment in Richmond Heights
4.91 out of 5 average rating, 56 reviews

Cozy Duplex I Centrally Located

MeritzaRating, 5 stars2 weeks ago
Amazing stay! Was everything we were expecting and was located in a nice neighborhood. Would definitely stay here again.
Guest favorite
Apartment in Alton
4.98 out of 5 average rating, 42 reviews

Historic Retro Modern King Bed Studio Apt

OliviaRating, 5 stars3 weeks ago
Beautiful home, beautifully furnished. Immediately felt at home.

Apartment rentals with a hot tub

Apartment in St. Louis
5 out of 5 average rating, 20 reviews

Pleasure Suite

HeatherRating, 5 stars7 months ago
This place was great for our visit to WashU. It was spacious, trendy, comfortable and clean. The building had a lot of cool spaces and amenities that we didn't get a chance to take advantage of but I would encourage others to save some time to utilize. It is an extremely walkabout area, right next to the park and a quick drive for us to WashU. Urus was accommodating to our early arrival which is always appreciated.
Superhost
Apartment in Bridgeton

Stunning Walkout Apartment w/Large Windows

LynettaRating, 5 stars3 months ago
Chanelle place was very private and peaceful. The location is surrounded by several restaurants and groceries stores. The pictures did no justice you have to book to experience what Chanelle airbnb is really about. I couldn't find a better place to stay, Chanelle was very friendly with a wonderful personality. If i'm ever in St.Louis again i will be staying at Chanelle airbnb.
Apartment in St. Louis
4.57 out of 5 average rating, 7 reviews

Quiet comfortable, 1 bedroom apt

DanetteRating, 5 stars20 months ago
This apartment was conveniently located and had a lot of nice amenities in the building, even though we didn’t have time to take advantage of them. Check in and out was so easy. I would stay here again the next time we’re in town.
Apartment in Downtown East St. Louis
3.8 out of 5 average rating, 10 reviews

“Saint Louis Luxe 1BR Retreat”

ShauntaRating, 5 stars1 month ago
it was a great place to stay i enjoy myself. we didn't get a change use the hot tub but the pool made up for that because it felt like an hot due to it being heated but very good place to stay 👌
Guest favorite
Apartment in Belleville
5 out of 5 average rating, 16 reviews

Cozy 2 Bedroom King bedroom, queen bed, sofa beds

RichiahRating, 5 stars5 days ago
A cozy little place for a work trip or change of scenery. Also located above a restaurant, which is convenient.
Apartment in Central West End
New place to stay

Central West End Gem

ClaireRating, 5 stars2 weeks ago
Helue’s place was very clean and easy to find! She answered any and all questions I had. She was very friendly and I had no issues at all whatsoever with my stay. Definitely recommended! Thank you Helue for everything!
Apartment in Soulard
4.82 out of 5 average rating, 34 reviews

Near City Garden Garage Parking

MikeRating, 5 stars1 month ago
This condo is awesome and is in the perfect location. We were able to walk almost everywhere. And it’s a quick and cheap Uber ride to Horseshoe Casino. The free parking is a huge plus. As for the condo itself, it is amazing. It has such an awesome modern look with cool looking decor. There was enough of whatever you would ever need in the kitchen. Being able to use the grill was nice, as we made a great steak dinner one of the nights. Keyless entry was great, although it takes a little bit of learning in the beginning. If you are like my wife and I, I do recommend bringing a couple of extra pillows. Communication was great. I highly recommend this condo and will definitely return next time we are in St. Louis. Five star all the way!

Quick stats about apartment rentals in Saint Charles

  • Total rentals

    30 properties

  • Nightly prices starting at

    G$4,196 GYD before taxes and fees

  • Total number of reviews

    2.7K reviews

  • Family-friendly rentals

    10 properties are a good fit for families

  • Pet-friendly rentals

    20 properties allow pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

Destinations to explore