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Vacation rentals in St. Ann

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in St. Ann

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A modern kitchen area features a contrasting blue cabinetry and wood paneling. A granite countertop adds a stylish touch, complemented by a small sink and utensils displayed in a white container. Natural light enters through a sliding glass door, enhancing the space.
Home in Saint Ann
4.89 out of 5 average rating, 62 reviews

Lower Level Layover

Keep it simple at this peaceful and centrally-located place. Located only 6 minutes to the airport. To accommodate our guests we are also happy to drive them to and from for short trips. Our home is walking distance to an AMAZING local cafe- the Sweet Spot! This is the lower level of our home. You will have full access to the lower level and it is completely separate. Entrance is around back through the walk out basement. Sometimes our small girl dogs will be out in the backyard which is shared

Top guest favorite
The charming front porch features a white wicker chair and a decorative wreath, inviting relaxation. Greenery surrounds the entryway, complemented by a well-maintained lawn. A gravel pathway leads from the porch to the driveway, creating a welcoming entrance to the guest house.
Home in Saint Charles
4.97 out of 5 average rating, 747 reviews

301 Guesthouse- Historic Main street-Katy Trail

Our 301 Guest House is new and completely remodeled in 2018! It’s ideal for one or two people with beautiful furnishings, great queen bed, lots of amenities, full kitchen, with big back yard and patio to enjoy outdoors too! Cable and FAST WiFi! Enjoy light Breakfast! BEST location, Great events year round within walking distance, with being only about 2 blocks from S. Main St, where there are about 100 gift shops n restaurants! Katy Trail is so close, with Spring, Summer, Fall and Xmas events!

Superhost
A light-filled bedroom features a spacious bed layered with a soft blanket and decorative pillows. A vase with flowers sits on the nightstand next to a wall-mounted lamp. Windows dressed with floral curtains provide views of the neighborhood.
Home in Saint Ann
4.77 out of 5 average rating, 112 reviews

Cozy Cottage in the City

This stylish place is perfect for your stay while in St. Louis. Whether here for family or business, this home is conveniently located just 15 minutes to Clayton, 20 min to downtown & the Central West End, or 15 minutes to St. Charles County. With only a 7 min drive (if you drive slow!!) to the airport, this 2 bedroom, 1 bath boasts a spacious kitchen, living room, & dining room for your stay-however long it may be! Please note that the piano in the photos is not available for guests to play.

Guest favorite
A well-lit living area features a dark leather sofa adorned with colorful cushions, complemented by a wooden coffee table and a blue area rug. Artwork and decorative accents enhance the space, with sunlight filtering through the windows, creating a warm, inviting atmosphere.
Apartment in Maryland Heights
4.88 out of 5 average rating, 199 reviews

Stunning Modern Apt| King bed 5 min CreveCoeurLake

Experience luxury and style in our St. Louis home. This second-floor residence features 2 modern bedrooms, a cozy living room, a fully equipped kitchen, a stylish bathroom, and a dedicated workspace with high-speed WiFi- blending comfort and elegance. Located in a secure Maryland Heights community, just minutes from Creve Coeur Lake, Westport Plaza, Hollywood Casino & Amphitheatre, and historic St. Charles. With plush bedding, premium amenities, and ample parking, we promise a seamless stay!

Superhost
A well-lit interior space features warm wooden flooring and a soft area rug. Natural light filters in from a nearby window, enhancing the inviting atmosphere of the room. The layout suggests a cozy and functional space suitable for relaxation or entertaining.
Home in St. Louis
4.79 out of 5 average rating, 260 reviews

Cheerful 1-bedroom, red brick, historic home

Keep it simple at this peaceful, historic, and centrally-located place. This red brick home is a piece of long-standing history (built in 1928), on a quiet one way street. It is just 5 minutes away from the airport & University of Missouri Saint Louis, and just 15 minutes from down town and central west end. It is literally central to just about any place you wish to visit in the Saint Louis area! There’s convenient and free on-street parking too! Come enjoy your time at The Ruby Brick Stay!

Guest favorite
A vibrant living area features bright green sofas with pink accent pillows positioned around a colorful area rug. An archway leads to a dining space with orange chairs, while blue walls and purple curtains add modern charm.
Bungalow in St. Louis
4.93 out of 5 average rating, 134 reviews

Near Airport • Fenced Yard • Hwy Access

9 minutes to STL Lambert Airport. With easy access to I-70, 170, 270 & 364. Comfortable home with fenced yard, fast WiFi, free parking, and self check-in. Quiet neighborhood ideal for work stays or travel. Fully equipped kitchen, washer/dryer, 2 smart TVs, and dedicated workspace. Close to dining and shopping, 20 minutes to downtown St. Louis. *Stays over 28 days require a signed lease, SD(refundable), $250 cleaning fee, & $200 per pet fee. Longer stays are welcome, inquire for more info!

Guest favorite
A charming two-story house features a gray exterior, framed by vibrant trees in autumn hues. Large windows allow natural light to enter, and a welcoming entrance hints at the cozy space within. A stone pathway leads up to the home, surrounded by a rustic landscape.
Tiny home in Saint Ann
4.88 out of 5 average rating, 273 reviews

Forest Edge Tiny House | 8 Min to Airport

Welcome to a private hidden gem 8 minutes from the airport with an oasis of an acre of woods surrounding the property! It’s a quiet getaway from the hustle and bustle of the city but only 8 min to the Airport, 15 miles to down town. 15 min to St. Charles area and 10 min to Hollywood Casino Amphitheatre. Perfect for couples, small family or single visitor to St. Louis! Dogs are welcome to stay for an additional fee. Early checkin/checkout available for $15/hour as availability allows.

Superhost
A bright kitchen featuring light green cabinetry and white countertops. An island with a circular design provides additional workspace. Natural light filters through the shutters above the sink, illuminating the dining area with a wooden table surrounded by four chairs.
Home in Creve Coeur
4.86 out of 5 average rating, 230 reviews

Home away from Home St. Louis Cnty Ladue Schools

15 min to Norwood Hills CC. Centrally located in Safe St. Louis County, Olivette/Creve Coeur area near many attractions, businesses, Universities, etc. Harkte Nursery is 2 houses away with farm fresh produce!! Lambert Intl Airport 13 min 7.7 miles Busch Stadium and St. Louis Ballpark Village, The Arch 20 min 13.8 miles Washington University 13 min 6.4 miles St Louis University 10 min St Louis Zoo, Forest Park, Science Center, Art Museum

Guest favorite
A lively living space is accented by a coral-colored sofa adorned with a mix of colorful cushions. A round dining table with red chairs is visible, alongside a wooden coffee table. Bright light filters through sheer curtains, enhancing the inviting atmosphere.
Home in St. Louis
4.91 out of 5 average rating, 34 reviews

International Airport Lambert Home 2BR

Welcome to Mabel’s Cottage. This charming 2BR home is minutes from STL airport. Each bedroom has a plush memory foam king bed. Perfect place for family and friends. **LOCAL GUEST & NO-PARTY POLICY:** Parties or gatherings are strictly forbidden. Local bookings are generally not accepted. Exceptions are for verified emergencies with prior approval. Unapproved local bookings may be cancelled immediately, with financial responsibility per Airbnb policy.

Top guest favorite
The living room area features a comfortable couch adorned with colorful cushions. A large television is mounted on the wall, while a small bar area with high stools provides a transition to the kitchen, which is visible in the background.
Home in St. Charles Historic District
4.99 out of 5 average rating, 108 reviews

Cottage on Historic Main St- Low Cleaning Fee

MESSAGE FOR SHORT STAY DISCOUNT Walk to everything on Historic Main Street St. Charles! Stay in a stylish 2BR steps from top dining, shops, nightlife & Ameristar Casino. 12 mins to STL Airport. Fast Wi-Fi, Smart TV, full kitchen, free parking & easy self check-in. Perfect for couples, weekend getaways & business stays. Unbeatable location, step outside directly onto Main Street in this vibrant, walkable district. Check out our 5★ reviews!

Superhost
Home in Saint Ann
4.77 out of 5 average rating, 22 reviews

Spacious Modern 2BR | King bed | Close to Airport

Modern, renovated 2BR apartment. King bed with added mattress topper. Queen bunk beds for flexible sleeping. All beds have 12-inch memory foam mattresses. Two living areas for work and relaxation. Large Roku TV for streaming. Fast WiFi and workspace. Fully equipped kitchen and in-unit laundry. Off-street parking for two vehicles. Pets welcome with fee and refundable deposit. Located near a park with typical neighborhood activity.

Guest favorite
Home in St. Louis
4.93 out of 5 average rating, 27 reviews

Modern St. Louis Retreat- LOW Cleaning Fee

Welcome to your cozy, centrally located escape in the heart of St. Louis! This beautifully designed space features an open layout, plush bedding, and a fully stocked kitchen, everything you need for a relaxing and convenient stay. Kick back on the comfy sofa with your favorite shows on the smart TV, or stay productive with fast, reliable Wi-Fi. Whether you’re visiting for work or fun, the space is thoughtfully set up for both.

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