Lee County vacation rentals

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Top-rated vacation rentals in Lee County

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Cape Coral

4.97 out of 5 average rating, 136 reviews

Cozy Studio with sunny outdoor patio

Peaceful & centrally located studio with private patio. 15-20 minutes from downtown Cape Coral & downtown Fort Myers. Driving distance to several beaches. There’s a kitchenette for basic cooking. oKing size bed! The studio is attached to the main house but is a completely separate & private space with a private entrance. Private patio with table. Beach essentials included. Cape Coral Yacht Club beach 15 min away Ft. Myers Beach 35 min away Sanibel Beach 40 min away Naples Beaches 60 min away

May 6 – 13

G$17,131 GYD per night

Guest favorite

Home in Cape Coral

4.89 out of 5 average rating, 19 reviews

Cozy Cape Coral Home | Newly Built with Game Room!

Relax in this family- friendly home 35 mins from the beach! We are pet friendly and provide everything needed for a peaceful getaway. Here you’ll find a BBQ grill for the adults and a fun-filled game room for the kids, so there is really something for everyone! Sun Splash Family Waterpark is only 15 minutes away from the house! Only 20 minutes away you’ll find Sunset Ski and Watersports where you can enjoy a dolphin tour, rent jetskis, rent banana boats, and even go on a beautiful sunset cruise!

Jun 22 – 29

G$15,019 GYD per night

Guest favorite

Guesthouse in Fort Myers

4.98 out of 5 average rating, 621 reviews

Hints of Key West in Fort Myers' Historic District

Tucked away in tranquil Dean Park Historic District. Built in 1925, this carriage house has been completely renovated in 2016. It is over a garage, there are stairs. Stroll to downtown Fort Myers River District, and enjoy the restaurants, nightlife, and cultural events. Take advantage of all the activities the area has to offer, and at the end of the day come back to this peaceful oasis. Our place can accommodate couples, older child (twin air mattress available), business travelers. No pets.

Jul 23 – 30

G$27,662 GYD per night

Superhost

Home in Fort Myers

4.86 out of 5 average rating, 564 reviews

Vacation house next to Sanibel / free amenities

Stay on adventure's doorstep! Biking distance (5 miles) to FMB and Sanibel island (beaches, salt water fishing, paddle boarding, kayaking ). Are guests enjoy free amenities: 1. Breakfast items (eggs, bagels, apples, coffee and tea) 2. Cruise style bikes, 2 x SUP 3. Beach chairs (Rio - Beach) 4. Beach umbrella 5. Cooler and beach towels 6. Secured Wi-Fi 7. Amazon TV, Hulu, Disney +, ESPN + and Netflix 8. Parking for two cars 9. Washer and dryer 10. BBQ 11. Kids toys and books and more....

Jun 2 – 9

G$19,106 GYD per night

Guest favorite

Home in Cape Coral

4.87 out of 5 average rating, 178 reviews

Recently Renovated Home with Pool in SW Cape Coral

The perfect getaway for families at our recently renovated house with pool and grill! Half an hour by car from famous beaches. Create lasting memories. Relax in the comfortable living area, and unwind in well-appointed bedrooms. Outside, make a splash in the refreshing pool or sizzle up a feast on the grill. Explore beaches, dine at charming restaurants, and enjoy outdoor activities. We ensure a memorable stay. Book now for an unforgettable family vacation! Pool heater from November to March.

Oct 9 – 16

G$30,873 GYD per night

Superhost

Guesthouse in Fort Myers

4.83 out of 5 average rating, 266 reviews

Coastal Cottage

Our guest house features a separate entrance, cozy full sized bed, clean bathroom, and includes homey amenities. You’ll be in the perfect location to shop, dine, and enjoy the nightlife of Downtown Ft. Myers or take a short trip and enjoy our Gulf Coast beaches. Our comfortable “she-shed” has a Murphy bed you can leave down for the duration of your stay, or easily lift up to provide room. Whether on a business trip or traveling as a couple, our "coastal cottage” will fit your needs perfectly.

Aug 29 – Sep 5

G$13,314 GYD per night

Guest favorite

Home in Fort Myers

4.8 out of 5 average rating, 264 reviews

Amazon Bungalow near Sanibel & Fort Myers Beach

Tropical setting. Peaceful/quite neighborhood. Bunche Beach 2 miles, Sanibel Island 3.5 miles, Fort Myers Bch 5 miles. Home is set up as a duplex, with TWO COMPLETELY SEPERATE & PRIVATE entrances, kitchens, living rooms, bedrooms, bathrooms & laundry rooms for COMPLETE PRIVACY. The Bungalow is a 1 King bed, 1 full bathroom & shower with large living room, kitchen & porch. Perfect for Couples! • 1/2 mile to Restaurants and Shopping • Close to Shellpoint Golf-Course • FREE Wi-Fi and Cable-TV

Sep 6 – 13

G$23,375 GYD per night

Guest favorite

Guest suite in Fort Myers

4.97 out of 5 average rating, 229 reviews

Clean studio unit with bathroom and living room

Enjoy a cozy stay in our studio. We're centrally-located in the heart of Fort Myers, with the interstate, RSW airport and Gulf Coast Town Center shops right around the corner. The beach is only a 25 minute drive, 10 minutes to the outlets, and 25 minutes to downtown. It's nice and quiet inside, with a place to work, relax to some TV, and has a comfortable queen size bed and a futon for an extra person. We have a full bathroom, mini-fridge, microwave, towels and plates to enjoy a meal.

Apr 18 – 25

G$21,512 GYD per night

Guest favorite

Guest suite in Matlacha Isles-Matlacha Shores

4.84 out of 5 average rating, 316 reviews

Moon Shell Hideaway

Private entrance to your one bedroom plus den (with queen size sleeper/sofa) apartment attached to main house. Direct access to the Gulf of Mexico. Bedroom has a queen size bed and the den has a queen size sleeper/sofa. The den doubles as your kitchenette and sitting area with double sliding glass doors that open up to the shared pool and dock area. Gas grill and microwave for cooking (no stove). Boat to five restaurants. Visit the Matlacha Art Galleries. Fish off the dock. WELCOME!

Nov 17 – 24

G$18,890 GYD per night

Guest favorite

Farm stay in Fort Myers

4.98 out of 5 average rating, 131 reviews

Private farmhouse stay at Dim Jandy Ranch.

Take it easy at this unique and tranquil getaway. A beautifully appointed bed and bath in a separate building from the house. We have goats, donkeys and peacocks. You can sit and relax on your private, beautiful lanai or any of our farm tables placed around the property. Join us as we feed the goats and donkeys. Or even join in one of our G.O.A.T. Yoga classes! We're easily located close to I-75, airports, shopping, beaches, downtown. Perfect for couples or solo travelers.

Dec 27 – Jan 3

G$30,463 GYD per night

Superhost

Guesthouse in Fort Myers

4.81 out of 5 average rating, 256 reviews

Nature's Romance

A romantic, private, relaxing retreat in the calm area right off Orange River in beautiful Buckingham. Our guesthouse is completely remodeled with all the amenities needed. The unit sits more than 60 ft. from the main house, with its own private driveway, and parking for whatever you may bring. It is hundreds of ft. to any other neighbor so you have nothing but the captivating nature while still being close to our Fort Myers metropolitan life. (LESS THAN 5 MINUTES TO I-75.)

May 13 – 20

G$14,294 GYD per night

Guest favorite

Apartment in Fort Myers

4.94 out of 5 average rating, 128 reviews

Peaceful Retreat #2

Welcome to Peaceful Retreat #2. This Large Studio Apartment Offers a plush King Sized Bed, The Kitchenette is complete with Microwave, Mini Fridge, Toaster and Drip Coffee Pot, a fairly large walk in Shower with sitting area and an over sized walk in Closet, cute little dinette set and two relaxing chairs to watch your favorite show, Enjoy your Morning Coffee in the Lushly Landscaped quaint Courtyard with the sound of birds chirping and water cascading.

Nov 8 – 15

G$15,796 GYD per night