Pet-friendly vacation rentals in Lee County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Lee County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite

Cottage in Matlacha

4.88 out of 5 average rating, 135 reviews

Mojito Island Cottage

Update: In September 2022 we were affected by Hurricane Ian. We had just over 5 feet of flooding in our treasured cottage. We have worked tirelessly to put everything back together. All new tile, walls, electric, lighting, furniture, and we even improved the bathroom! Spacious tropical home with water view from our back yard lanai. Boat Dock with Cleaning Fish Station, BBQ beautiful sunsets with fish jumping in our canal. New large kitchen and one block from art galleries, restaurants and bars.

Sep 5 – 12

G$24,003 GYD per night

Guest favorite

Home in Cape Coral

4.89 out of 5 average rating, 19 reviews

Cozy Cape Coral Home | Newly Built with Game Room!

Relax in this family- friendly home 35 mins from the beach! We are pet friendly and provide everything needed for a peaceful getaway. Here you’ll find a BBQ grill for the adults and a fun-filled game room for the kids, so there is really something for everyone! Sun Splash Family Waterpark is only 15 minutes away from the house! Only 20 minutes away you’ll find Sunset Ski and Watersports where you can enjoy a dolphin tour, rent jetskis, rent banana boats, and even go on a beautiful sunset cruise!

Jun 23 – 30

G$15,045 GYD per night

Guest favorite

Home in Cape Coral

5.0 out of 5 average rating, 7 reviews

Pet friendly 2/1.5, perfect for long term stays

With no pet fees or deposits and a fully fenced in private back yard you can rest easy knowing your pet will have space and feel at home throughout your stay. This is the perfect place for a travel nurse or traveling professional with multi-month commitments. A fully fenced in house with 2 bedrooms, 1.5 bathrooms, 2 parking spots, screened lanai and fast WiFi. Located 9 mins from downtown, 10 mins from Cape Coral hospital, 12 mins from the local beach, 30 mins from the Sanibel and SWF airport.

May 27 – Jun 3

G$20,923 GYD per night

Guest favorite

Home in Cape Coral

4.98 out of 5 average rating, 45 reviews

Cozy 3BR home in the Cape

Come relax in the Cape! Spacious living room with a 75-inch 4K TV with: Netflix, Disney+, Hulu+ LiveTV, ESPN+ and Amazon Prime Video. The kitchen is fully equipped with a coffee and espresso station, cooking basics, and many teas. Enjoy a master bedroom with a king-size bed, a 55 inch 4K TV, and an ensuite bathroom. A second bedroom with a queen-size bed and a third bedroom with 2 twin-size beds and a work from home office space with high-speed wifi. There is a second bathroom with a bathtub.

May 15 – 22

G$31,974 GYD per night

Guest favorite

Home in Fort Myers

4.96 out of 5 average rating, 149 reviews

Newly remodeled 3bd/2ba home

Enjoy everything that South West Florida has to offer from this centrally located, beautifully remodeled home, including 4 bd/2 ba, that comfortably sleeps 4. If you plan to have a party or event, this place is NOT for you. The neighbors are very strict in terms of noise and large groups of people. It is close to popular attractions, shopping, dining, and outdoor recreation including the wonderful Lakes Regional Park where you can hike, kayak, picnic and much more! LICENSE: TAP4605693

Sep 29 – Oct 6

G$35,288 GYD per night

Guest favorite

Guesthouse in Fort Myers

4.97 out of 5 average rating, 279 reviews

Chameleon Guest Cabana

The 300 Sq Ft Cabana Studio Apartment with Separate full Bathroom!! The Cabana with mini fridge, microwave, Keurig and toaster is completely private and was built in 1925 and recently updated is tucked away in a lovely established and historic neighborhood very close (walking distance) to The Edison Ford Winter Estates. Downtown Ft. Myers is a walkable distance if you are accustomed to walking but may be a little far for some. The neighborhood is very safe and quiet. Safe Travels

Mar 8 – 15

G$21,030 GYD per night

Guest favorite

Home in Fort Myers

4.94 out of 5 average rating, 273 reviews

Whole cozy house

Entire cozy house just for you friends and family. Perfect to spend a pleasant and relaxed moment. If you plan to have a party or event, this place is NOT for you. The neighbors are very strict in terms of noise and large groups of people. Well maintained house. CLEAN POOL BUT NOT HEATED. Walk in to a living area and separated dining. 20 minutes to airport, 25 minutes to the beach, fine dining and entertainment. For a virtual tour, click on the cover photo twice.

Jun 27 – Jul 4

G$38,119 GYD per night

Guest favorite

Home in Cape Coral

5.0 out of 5 average rating, 14 reviews

Your 4 Bedroom family escape at Cape Villa

Be the first to stay at this newly furnished vacation home. Remodeled in 2022, the open-air floor plan and 4 bedrooms will give your family the space needed to relax. Soak up the sunshine in the huge yard and with a screened-in lanai. Beaches & water parks are a short drive away. Includes 2 large smart TVs, High Speed WIFI, A Gaming desk, board games, private garage parking & more. Bring the whole family to this great place with lots of room for fun.

May 28 – Jun 4

G$22,327 GYD per night

Guest favorite

Home in Cape Coral

5.0 out of 5 average rating, 9 reviews

Cape Oasis Pool Heater

.Enjoy a stylish experience at this centrally-located -5 minutes from Sunsplash water park -close to Sanibel beach -30 min from Fort Myers Beach -very closed to Sanibel Beach you can enjoy restaurant with amazing views and sunset . -minutes away from Matlacha seafood restaurants -4 bedroom -3 bathroom -2 car garage -new construction 2022 -Fantastic neighborhood - Plenty Backyard -Amazing modern pool -Barbecue Area -wine cooler

Jun 19 – 26

G$28,351 GYD per night

Guest favorite

Home in Cape Coral

4.96 out of 5 average rating, 158 reviews

Surfside Elegance SW Cape Coral Luxe Vacation home

This elegant spacious 3 Bedroom + Den, 3 Bathroom house with split floor plan and large living room will truly make you feel home! High ceilings, a lot of natural light, large rooms, amazing Florida canal view, large heated pool. Fully remodeled in 2017 and feels like new. Location is amazing, close to Marina, Cape Harbour, restaurants. Excellent, beautiful and safe neighborhood. This home is perfect for your vacation!

Aug 1 – 8

G$37,876 GYD per night

Superhost

Home in Fort Myers

4.88 out of 5 average rating, 193 reviews

The Beachy Retreat

This is the ultimate getaway for our guests. Our cozy newly renovated retreat is in the perfect location that is close to the beach, near all the best restaurants, and has all the amenities you will need for a breezy family vacation. Just a short 10 min drive to all the best beaches (Sanibel Island and Ft. Myers Beach), shopping locations, and more!

Aug 18 – 25

G$23,014 GYD per night

Superhost

Home in Fort Myers

4.9 out of 5 average rating, 20 reviews

Tiny Treasure

Looking for quick beach access to Sanibel Island and Ft Myers Beach? Look no further! This cozy little bungalow is only 5 miles to the Sanibel Causeway and 5 miles to Times Square on Ft Myers Beach AND less than one mile to a shopping plaza that includes a super Target. Location doesn't get much better than this!

Sep 26 – Oct 3

G$17,514 GYD per night