Vacation rentals in Roxana

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Roxana

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Home in Millstadt

4.93 out of 5 average rating, 223 reviews

Deluxe Barndominium | King bed + Pkg

Enjoy the unique historical setting of this recently remodeled Barndominium, just 5min away from DT Millstadt and 20min from DT St. Louis. Learn the old Illinois ways by relaxing in a contemporary decorated barn that was once an honor system farm stand. Blend of comfort, stylish décor & a rich amenity list are there to satisfy your every need. ✔ 2 Comfy Bedrooms (King Bed, Single over Double Bunk) ✔ Fully Equipped Kitchen ✔ Open Living Area ✔ 55’’ Flat-Screen TV ✔ Fast internet See more below

Jun 25 – Jul 2

G$26,465 GYD per night
Guest favorite

Apartment in Edwardsville

4.91 out of 5 average rating, 223 reviews

Edwardsville Apartment - The Woodland Suite

The apartment in the lower level of the home has recently been renovated, with a walk-out private entrance, a full kitchen & dining area, full bath, bedroom and a cozy living space. Situated just 35 minutes from downtown St Louis, in the safe and affluent community of Edwardsville, this property sits in a quiet cul de sac on a wooded lot right in the heart of the city. We are just a few minutes from the SIUE campus, Edwardsville HS, & I-270. Coffee/restaurants/shops/parks/trails just 2 min away.

Jul 9 – 16

G$30,796 GYD per night
Guest favorite

Home in Granite City

4.98 out of 5 average rating, 119 reviews

Cozy 2-bedroom home minutes from ST. Louis, MO

Welcome to the Sheridan House. This cozy 2-bedroom home is located in a quiet neighborhood. It sets on a corner lot with a large back yard and a parkway across the street. Spend relaxing evenings on the patio, grilling your dinner. Or challenge your partner to a game of ping pong in the basement rec room. Centrally located, you can spend your days exploring attractions in Saint Louis, Mo, Alton and Edwardsville, IL. Just minutes from World Wide Technology Raceway, Busch Stadium, & the Arch.

Oct 12 – 19

G$24,235 GYD per night

Popular amenities for Roxana vacation rentals

Other great vacation rentals in Roxana

Guest favorite

Home in Saint Charles

4.98 out of 5 average rating, 483 reviews

301 Guesthouse SuperHost/Shop Discounts/Katy Trail

Nov 6 – 13

G$27,994 GYD per night
Guest favorite

Home in Saint Charles

4.98 out of 5 average rating, 170 reviews

Bright & Cozy Shotgun 1 Block from Historic DT.

Jul 3 – 10

G$25,287 GYD per night
Guest favorite

Home in Roxana

4.95 out of 5 average rating, 55 reviews

The House Next Door

May 7 – 14

G$31,192 GYD per night
Superhost

Home in Wood River

5.0 out of 5 average rating, 9 reviews

Cozy 3 bedroom home close to STL

Dec 6 – 13

G$26,630 GYD per night
Guest favorite

Apartment in Alton

4.87 out of 5 average rating, 55 reviews

Hearth & Home

Dec 31 – Jan 7

G$26,360 GYD per night
Guest favorite

Home in Troy

4.98 out of 5 average rating, 44 reviews

No Frills Home on 2 Acres to yourself!

May 21 – 28

G$20,436 GYD per night
Guest favorite

Camper/RV in Edwardsville

4.98 out of 5 average rating, 54 reviews

luxury RV tiny home- 5 acre property- SIUE- STL

Apr 17 – 24

G$25,007 GYD per night
Guest favorite

Home in Alton

4.86 out of 5 average rating, 35 reviews

Quiet, sunny Alton charmer.

Aug 17 – 24

G$21,760 GYD per night
Guest favorite

Apartment in Edwardsville

4.97 out of 5 average rating, 73 reviews

Cozy Historic Downtown Edwardsville Charmer

Dec 17 – 24

G$26,207 GYD per night
Guest favorite

Home in Alton

4.99 out of 5 average rating, 74 reviews

Cozy renovated 2 bdrm cottage w/ dedicated office

Mar 12 – 19

G$18,524 GYD per night
Guest favorite

Apartment in Alton

4.96 out of 5 average rating, 28 reviews

Todays comfortable & cozy loft.

Jun 19 – 26

G$28,298 GYD per night
Guest favorite

Home in Granite City

4.93 out of 5 average rating, 41 reviews

"Blue Bliss Retreat in Granite"n

Jun 11 – 18

G$20,436 GYD per night

Destinations to explore

  1. Airbnb
  2. United States
  3. Illinois
  4. Madison County
  5. Roxana