Vacation rentals in Pine Island Center

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Top-rated vacation rentals in Pine Island Center

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Top guest favorite
An outdoor space features a screened-in pool area with a rectangular swimming pool and a hot tub. Poolside lounge chairs with blue cushions are arranged around a small table. Lush greenery is visible in the background, enhancing the private ambiance.
Villa in Cape Coral
4.96 out of 5 average rating, 112 reviews

LAST Minute! NEW Villa-Heated Saltwater Pool & Spa

Experience Cape Coral like never before all from this gorgeous 3bedroom, 3bath villa. This elegant villa boasts a vibrant interior decorated with Italian furniture and fully equipped kitchen. Begin your day with a few laps in the private pool before heading to the Yacht Club Public Beach, Sun Splash Family Waterpark or Pine Island to soak up some sun! After adventurous days, continue making memories back home with a family barbecue and a soak in the hot tub or have a movie night with loved ones!

Top guest favorite
The view from the dock features calm waters reflecting sunlight, with a backdrop of palm trees and charming homes lining the canal. Wooden posts mark the dock, while boats are visible along the shore, enhancing the peaceful coastal atmosphere.
Cottage in Hamlet
4.9 out of 5 average rating, 162 reviews

Mojito Island Cottage

Update: In September 2022 we were affected by Hurricane Ian. We had just over 5 feet of flooding in our treasured cottage. We have worked tirelessly to put everything back together. All new tile, walls, electric, lighting, furniture, and we even improved the bathroom! Spacious tropical home with water view from our back yard lanai. Boat Dock with Cleaning Fish Station, BBQ beautiful sunsets with fish jumping in our canal. New large kitchen and one block from art galleries, restaurants and bars.

Guest favorite
A bright and inviting dining area features a table set for dinner, accompanied by modern chairs, and is situated adjacent to a well-equipped kitchen. The open living space showcases comfortable seating and large windows offering views of the outdoors, allowing natural light to fill the room.
Home in Cape Coral
4.97 out of 5 average rating, 141 reviews

Beach Centric & Cozy 3BR Home

POOL CONSTRUCTION IN YARD Come relax in the Cape! Spacious living room with a 75-inch 4K TV with: Netflix, Disney+, and Prime Video. The kitchen is fully equipped with a coffee and espresso station, and a very well equipped kitchen. Enjoy a master bedroom with a king-size bed, a 55 inch 4K TV, and an ensuite bathroom. A second bedroom with a queen-size bed and a third bedroom with 2 twin-size beds and a work from home office space with high-speed wifi. There is a second bathroom with a bathtub.

Guest favorite
A dining area features a white table surrounded by six chairs, topped with blue placemats. A decorative vase filled with flowers sits in the center. The walls are lightly colored and display a wall sign that reads 'RELAX.' Pendant lights provide warm illumination.
Home in Bokeelia
4.92 out of 5 average rating, 13 reviews

The Little Yellow Retreat with boat parking

Welcome to The Little Yellow Retreat! Your cozy escape on Bokeelia Island awaits. This charming home features a bright living room, fully equipped kitchen, and cheerful bedrooms, perfect for families, couples, or solo travelers. Relax in the lush backyard with fruit trees and a covered patio, or walk to nearby restaurants and a pool. Two scooters are available for $20/day for both, perfect for exploring the island. Beaches and marinas are close by. Your island getaway is waiting—book now!

Top guest favorite
A spacious pool area is viewed with a clear turquoise pool reflecting sunlight. Five lounge chairs are positioned around the pool, with a wooden dock extending towards the water. Lush greenery and potted plants add a natural touch to the surroundings.
Guest suite in Matlacha Isles-Matlacha Shores
4.85 out of 5 average rating, 364 reviews

Moon Shell Hideaway

Private entrance to your one bedroom plus den (with queen size sleeper/sofa) apartment attached to main house. Direct access to the Gulf of Mexico. Bedroom has a queen size bed and the den has a queen size sleeper/sofa. The den doubles as your kitchenette and sitting area with double sliding glass doors that open up to the shared pool and dock area. Gas grill and microwave for cooking (no stove). Boat to five restaurants. Visit the Matlacha Art Galleries. Fish off the dock. WELCOME!

Top guest favorite
An open living space showcases comfortable leather seating centered around a television. A dining table is set nearby, complemented by natural light from large windows. The modern kitchen is visible in the background, featuring white cabinetry and a stylish island.
Home in Cape Coral
4.98 out of 5 average rating, 43 reviews

Cozy Cape Coral Home for a Great Getaway by S&F

Relax with the whole family at this peaceful place to stay. Enjoy our gourmet kitchen with open living space. You will have full access to 3 bedrooms and 2 bathrooms as your respite in Southwest Florida. Our home has a lot to offer. Feel free to use our patio in which you have access to a grill and a wood-burning pizza oven. If reading is your hobby, take a read from our guest library and enjoy the fireplace (with no mess). We take pride in our home and welcome you as our guests.

Top guest favorite
An open-concept living area is showcased, featuring a modern sectional sofa and a sleek coffee table. Large glass doors lead to the outdoor space, allowing natural light to fill the room. A contemporary dining area with stylish fixtures is visible in the background.
Villa in Cape Coral
5 out of 5 average rating, 58 reviews

BRAND NEW Luxury Villa w/Heated and Chilled Pool

Brand new high-end 3 bedroom 3 bath designer home, elegantly decorated with incredible views and direct no-bridge Gulf access. Come and make your lifetime memories in this elegantly appointed executive villa. Located near Matlacha, Sanibel, Fort Myers, and Naples. Extra wide canal with only trees opposite, a salt water lagoon, and just off the spreader canal means incredible solitude and privacy in your elegant oasis retreat.

Top guest favorite
A charming yellow house is framed by lush greenery and vibrant red flowers. The inviting porch features a railing, while a pathway leads to the entrance. Tropical palm trees sway gently in the background under clear blue skies.
Home in Bokeelia
5 out of 5 average rating, 24 reviews

Bountiful Bokeelia

Seasonal rental, January February March available to book for all three months. You’ll be glad you did!! Forget your worries in this spacious and serene oasis. Professionally decorated, Coastal Chic, extremely quiet, 3 acre fenced and gated property off the beaten path on Pine Island. So close yet so far away! The immediate mainland has all that you could possibly need. The property boasts a unique natural swimming pond.

Top guest favorite
A well-lit bedroom features a spacious bed with yellow-accented pillows and a decorative blanket. Neutral walls and tiled flooring offer a calming environment. A dresser and mirror provide ample storage, while a nightstand with a lamp adds functionality. A ceiling fan ensures comfort.
Home in Bokeelia
5 out of 5 average rating, 10 reviews

Cozy clean duplex

Have your vacation in Paradise! This duplex is located in the heart of Pine Island a couple of blocks from the four way stop (center of the island). Full Kitchen Sleeper Sofa in living room. Walking distance to: Restaurants and Delis Shops Spa Yoga Studio Park Library Museum Community POOL We are 5 minutes away from the touristic town of Matlacha with all its artsy shops and fantastic restaurants.

Top guest favorite
A covered screened-in porch features a wicker couch and a matching chair, both adorned with blue patterned cushions. Lush greenery creates a natural backdrop, enhancing the tranquil atmosphere of the space. The tiled floor offers a cool, inviting surface for relaxation.
Guest suite in Cape Coral
4.9 out of 5 average rating, 113 reviews

Cape Coral Cozy Quiet Private Efficiency Apartment

This NON-SMOKERS effenciency apartment has a comfy firm King mattress with a foam topper. Melt your stress away as you sleep PLEASE NOTE: The Apartments laundry is done on a weekly basis… but personal laundry can be done in a local Laundromat. A small kitchen area (NO STOVE) private entrance in a quiet ,safe neighborhood.Close to shopping and hospitals and other Florida The Air is set at 77*

Top guest favorite
The exterior of a single-story home is showcased, featuring a manicured lawn and landscaping. The structure has a light-colored facade and a sloped roof. A vehicle is parked in the driveway, with palm trees and a blue sky completing the serene atmosphere.
Home in Cape Coral
5 out of 5 average rating, 16 reviews

Villa Coral

Bienvenidos a VillaCoral, una casa familiar espaciosa de 4 dormitorios y 2 baños en Cape Coral, con su terraza comoda para reunirse con familiares y amigos. El garaje doble y un amplio patio trasero garantizan comodidad. A solo minutos de las mejores playas y restaurantes de la zona. ¡Su escapada perfecta al sol les espera!

Guest favorite
Apartment in Cape Coral
4.87 out of 5 average rating, 15 reviews

Peaceful Cape Coral Escape

Relax and recharge in this quiet, cozy getaway studio—perfect for solo travelers or couples. Located in a tranquil neighborhood, you’re just minutes from Fort Myers Beach and all the best that Cape Coral has to offer. Enjoy a peaceful stay close to restaurants, shops, and waterfront attractions.

Popular amenities for Pine Island Center vacation rentals

  1. Airbnb
  2. United States
  3. Florida
  4. Lee County
  5. Pine Island Center