
House vacation rentals in Penonomé
Find and book unique houses on Airbnb
Quick stats about house rentals in Penonomé

Total vacation rentals
Explore 40 vacation rentals in Penonomé

Nightly prices starting at
Penonomé vacation rentals start at G$4,184 GYD per night before taxes and fees

Verified guest reviews
Over 560 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
30 of Penonomé vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Penonomé rentals

4.7 Average rating
Penonomé stays receive an average rating of 4.7 out of 5 from guests
Top-rated house rentals in Penonomé
Guests agree: these houses are highly rated for location, cleanliness, and more.

Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.
4.98 out of 5 average rating, 222 reviews
Vista Pacífica | Jacuzzi, Piscina, Vistas y Alexa
Somos una casa de campo para máximo 10 personas en un terreno cercado de 1,000 m² en lo más alto de Valle Los Lirios, Las Uvas de San Carlos, manteniendo una sensación de aislamiento. Ubicada en un vecindario con videovigilancia 24/7 y garita de seguridad. Ofrece vistas al mar, Valle de Antón y bosques. Relájate en el jacuzzi con hidromasaje y jets o nada en la piscina. Contamos con hamacas, barbacoa, mesa de ping pong, fogata y asistente de voz Alexa. Hay estacionamiento para máximo 6 autos.
4.82 out of 5 average rating, 109 reviews
Casa Coco - Beautiful Mountain Villa With AC
Elegant and modern, our home strikes the perfect balance between luxury and warmth. With ample space to accommodate large groups and families, as well as cozy and inviting for smaller groups. The yard features a covered social area, ideal for relaxing or entertaining. A lush garden adorned with vibrant greenery includes a charming mango tree and mountain peak views. A 5 minute walk to restaurants and the open air market. If you have a group larger than 12- please reach out to us directly.
4.93 out of 5 average rating, 103 reviews
Spacious House | Garden and Terrace | Pet Friendly
Discover the pleasure of staying in a private, elegant, and light-filled villa within the exclusive Playa Blanca Beach & Lagoon. Start your day with the tropical breeze on the terrace, relax by the pool, and enjoy a short 10-minute walk to the beach. Perfect for families and travelers seeking rest, security, and resort-style comfort. Ideally located 10 minutes from Scarlett Martínez Airport and 2 hours from Panama City, it's the perfect place for an unforgettable getaway by the sea.
4.98 out of 5 average rating, 146 reviews
Casa de Campo
This unique house was inspired out of a US Mountain Home named "The Three Deers". As per our knowledge, no other house in our country has a balanced wood - cement - and steel-building foundations achieved here. Made from the best fine Bocas del Toro and Chiriqui's large hardwood pieces, we did not want to mimic any fake wood structures. Located in the central street of Anton Valley, most of your tourist or daily activities can be arranged within a very short walking distance.
4.76 out of 5 average rating, 104 reviews
El Palmar, playa a 50 metros
Escucha las olas desde la privacidad de nuestra terraza y crea recuerdos inolvidables en este alojamiento único y familiar a pocos paso de la playa con piscina privada. El palmar es una comunidad tranquila con varios restaurantes disponibles a unos pasos de la casa. La propiedad esta totalmente cercada para la tranquilidad y seguridad de hijos y sus mascotas adicional tienes wifi, TV cable en ambas habitaciones y aires acondicionados en la sala comedor y en todas las recamaras
4.88 out of 5 average rating, 182 reviews
Modern House with Great Views and Heated Pool
Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.
4.82 out of 5 average rating, 336 reviews
Villa Acuario
Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.
4.76 out of 5 average rating, 170 reviews
Villa Cecilia-Acogedor estudio en Penonomé Centro
Una casa auténtica del interior de Panamá, renovada con calidez y buen gusto. Esta habitación privada cuenta con una cama matrimonial cómoda, ideal para parejas, y espacio opcional para agregar una cama individual. Totalmente equipada: sala, cocina, comedor, escritorio para trabajar; ideal si buscas tranquilidad sin perder los espacios de una casa completa. Ideal para: parejas, familias pequeñas (2 adultos + 1 niño), viajeros solos que buscan privacidad.
5.0 out of 5 average rating, 3 reviews
Rustic family mountain home - 5 min walk to town!
Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.
4.96 out of 5 average rating, 201 reviews
Casa cómoda, cercada y segura.
En Casa las Hamacas, disfruta de la sencillez de este alojamiento espacioso, tranquilo y céntrico. Podrás disfrutar del agradable clima penonomeño. Un lugar cerca de todo, centros comerciales, escuelas, hospital, montaña ríos y playas. Ambas habitaciones cuentan con aire acondicionado para garantizar tu descanso. A pocos minutos de la vía interamericana.
4.91 out of 5 average rating, 159 reviews
Panama del Mar
Panama del Mar, nestled in center of Buenaventura, is truly a tropical paradise with a variety of pools, cabanas, pristine beach, restaurants, spas, and everything that makes your vacation relaxing. This spacious home accommodates 12 guests and includes all the conveniences of home. Any further questions can directed to Sandra to 507-6980-1314.
4.96 out of 5 average rating, 113 reviewsPopular amenities for Penonomé house rentals
House rentals with a pool

OceanView-Rooftop Jacuzzi&Pool | Concierge Service
4.94 out of 5 average rating, 155 reviews
Villa en Playa Blanca
4.87 out of 5 average rating, 129 reviews
Coronado Coastal Villa • Walk to the Beach
4.82 out of 5 average rating, 169 reviews
3BR • 10 Min Drive to Beach • Pool • BBQ • WiFi
4.97 out of 5 average rating, 75 reviews
CasAna
4.98 out of 5 average rating, 40 reviews
Playa Malibu Beach House.
4.95 out of 5 average rating, 43 reviews
Casa de Verano | Cozy Mountain Retreat
4.82 out of 5 average rating, 74 reviews
9-Guest Villa near Bijao | Pool & Beach Access
4.93 out of 5 average rating, 29 reviewsWeekly house rentals

Guacamaya’s Hill View|3BR Country Home In Penonomé
4.89 out of 5 average rating, 18 reviews
Hospedaje la Casita
4.89 out of 5 average rating, 28 reviews
The trip house
5.0 out of 5 average rating, 29 reviews
La Florecita - Casa de campo en Valle de Antón
4.89 out of 5 average rating, 89 reviews
Un refugio sereno en el campo
4.95 out of 5 average rating, 61 reviews
La Casa de Alba María
4.89 out of 5 average rating, 9 reviews
Residencia en El Valle de Antón
5.0 out of 5 average rating, 10 reviews
Beautiful lovely house in Penonome, Panama
4.91 out of 5 average rating, 11 reviewsPrivate house rentals

Paradishaus in Natur in Playa Coronado mit Pool
4.94 out of 5 average rating, 35 reviews
Hermosa casa de campo
4.99 out of 5 average rating, 67 reviews
Beach & Golf VILLA CASA en Playa
4.92 out of 5 average rating, 72 reviews
Valle de Anton -A prime location secluded by trees
4.91 out of 5 average rating, 97 reviews
Beachfront Private Family-Friendly House | Nature
4.95 out of 5 average rating, 44 reviews
Casa de Campo con Vista
4.96 out of 5 average rating, 23 reviews
Cabaña Pet Friendly en Altos del María
4.78 out of 5 average rating, 67 reviews
The Jungle House | Hacienda Valle Paraiso
5.0 out of 5 average rating, 28 reviewsDestinations to explore
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