Vacation rentals in Palmyra

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Top-rated vacation rentals in Palmyra

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Guest favorite

A serene lakeside view captures the lake house reflecting on calm waters at sunset. The structure is framed by trees and the horizon glows with warm hues, while the sky transitions from deep blue to softer colors.

Cottage in Philadelphia

4.94 out of 5 average rating, 604 reviews

Frogmore Cottage on 5-acre lake, Enjoy Nature!

PLEASE ENTER CORRECT NUMBER OF GUESTS WHEN BOOKING. Enjoy nature on this five-acre lake on 25 well-manicured acres. Fabulous sunsets! For a tiny house it has a spacious lower level with vaulted ceiling and upper bedroom loft. Wifi & smart TV. Nice warm heat and cool AC. Outdoor activity includes hammocks, swimming, boating (canoe, kayaks, john boat). For fishing we have boats, nets & fish-dressing station (bring poles & bait). About 13 miles from Palmyra and Monroe, nearest gas and groceries.

Top guest favorite

An open living and dining area features a dining table surrounded by six chairs. A light fixture hangs above the table. A cozy sofa and TV are visible in the adjacent living space, with large windows allowing natural light to brighten the area.

Home in Quincy

4.99 out of 5 average rating, 139 reviews

The Spruce House

The Spruce House is a beautifully restored and fully updated 1930's style bungalow with all the modern amenities! The interior of the cozy home has been remodeled to meet all of your needs while traveling to Quincy. Located near Blessing Hospital and only four blocks from Quincy University's Q-Stadium, The Spruce House offers a beautiful kitchen, two bed rooms with king and queen beds, high-speed Wi-Fi, a spacious yard, off street parking and a wonderful and safe neighborhood. Let us host you!

Top guest favorite

A charming cabin sits adjacent to a tranquil lake, surrounded by lush greenery and colorful autumn foliage. A front porch features hanging plants, welcoming visitors to the peaceful outdoor space. Smooth stones outline the water's edge, creating a serene landscape.

Cabin in Camp Point

4.99 out of 5 average rating, 154 reviews

Oakbrook Akers Lakeside Cabin Retreat

Located in the heart of the country, Oakbrook Akers Cabin is an absolute retreat! Relax on the many porches overlooking the lake, take time to meander to the docks to fish, enjoy s'mores over the stone fire pit or spend the evening at the grilling station in our covered patio. In the winter, tuck yourself away in the cozy cabin complete with a wood burner, having a movie or game night (with popcorn of course)! Built by my father, we hope you cherish your time spent here just as our family has.

Top guest favorite

The living room features a comfortable blue sectional sofa paired with a wooden coffee table. Natural light filters through a window, casting patterns on the hardwood floor. A small white side table and a television are positioned in the space, creating an inviting setting.

Apartment in Palmyra

4.98 out of 5 average rating, 109 reviews

Main Street Haven: King Suite

Welcome to our luxurious Main Street Haven, nestled in the heart of a picturesque small town only minutes away from Historic Hannibal (12min) and Quincy IL (18min). This charming ground level unit features a luxurious king size bed that will give you the restful sleep you deserve. The new bathroom is furnished with modern amenities, and the large living room provides ample space to relax and unwind. The full kitchen is perfect for preparing meals, and is equipped with everything you may need.

Guest favorite

The kitchen features white cabinetry and modern black appliances. A spacious countertop offers seating at two metal stools. Natural light filters through the windows, illuminating the wooden flooring and classic tile backsplash.

Home in Hannibal

4.96 out of 5 average rating, 161 reviews

Little House in the Hollow

Enjoy a private peaceful setting that is Conveniently located. Large fenced in yard for the kids and/or pets. Also has a 4 person hotub which is available year-round. The house is fully stocked for convenience. The house also has covered parking, outdoor fire pit, BBQ grill a play place for the kids and more. You will be within walking distance of 2 National Landmarks (Mark Twain Cave, Cameron Cave) as well as our Winery and Giftshop. Located just two miles from Hannibal's Historic District.

Guest favorite

A comfortable living space is featured with two dark leather sofas and a recliner. A cream-colored area rug in a cowhide pattern rests on the dark hardwood floor. Natural light streams in through two windows, with patterned curtains framing the view of the outdoors.

Home in Palmyra

4.9 out of 5 average rating, 174 reviews

Cozy country 2-bedroom home with a view.

Make some memories at this unique and family-friendly place. Enjoy the view of horses grazing while sipping your morning coffee on the front porch. Drive to historic Hannibal, MO (11 miles). Book a guided farm tour with the owners and/or a riding lesson on one of their many rodeo horses. This house sleeps 6 with a king bed, queen bed, and couch fold-out queen bed. Need more room? (See the other listing for this option). The hostess is right next door to assist with any of your needs!

Guest favorite

A spacious covered porch features wooden decking and several chairs, providing a comfortable space to relax. The warm sunlight is seen setting over the open pasture, with trees lining the horizon, enhancing the serene outdoor view.

Farm stay in Quincy

4.88 out of 5 average rating, 119 reviews

Cozy and Convenient Guesthouse on Family Farm!

Right on the edge of town, and only a quick trip to everything in town, the guesthouse on our family farm is the perfect stay. It's quaint and cozy, yet convenient to the highway, shopping, restaurants, and groceries. You will feel right at home, whether you're cozying up to watch a movie, sitting on the front porch watching the sun set, or cooking breakfast in our full kitchen. Welcome to your farm away from home! Close to the airport! Right off the interstate 2 minutes from Walmart

Guest favorite

An antique wooden bed with a decorative headboard is centered against a textured brick wall. Soft pink bedding is arranged neatly on the bed. A small side table with a lamp and a colorful floral curtain is visible, complementing the warm tones of the wooden floor.

Home in Hannibal

4.94 out of 5 average rating, 102 reviews

Genevieve’s Federal House

This home is a fully restored 1 story Federal house, which you will have full access to. It is located close to the Mark Twain Boyhood Home, and right off Broadway. The house comes furnished with seating, furniture, and 2 Roku televisions. There are two bedrooms, one bathroom, a dining room, living room, and a kitchen. The home has central air conditioning and heating, washer and dryer, dishwasher, and a beautiful clawfoot cast-iron tub with shower. There is off street parking.

Superhost

The kitchen area features a granite countertop with wood accents and modern appliances, including an oven and refrigerator. Cabinets display coffee mugs and utensils, and a window with blinds allows natural light to enter, illuminating the space. Two wooden seating areas are positioned nearby.

Apartment in Hannibal

4.85 out of 5 average rating, 156 reviews

Farmhouse

Enjoy nostalgic downtown Hannibal in this unique apartment located on Main Street just steps from a movie theater, restaurants and bars, shopping, museums, the riverfront, and Mark Twain historic sites. With a private bedroom with flat screen television, living area with sleeper sofa and daybed, and a full kitchen the interior of this rental is sure to charm any visitor. Book for a weekend, a week, or longer.

Guest favorite

A modern kitchen is showcased with white cabinetry and stainless steel appliances. A marble island provides seating for four with metal stools. Natural light highlights the space, including a gas stove, oven, and built-in microwave, creating an inviting area for meal preparation.

Home in Quincy

4.94 out of 5 average rating, 322 reviews

❤️Quincy Quarters❤️

Quincy Quarters is a beautifully restored 1880’s Duplex with modern amenities and all the historic charm. This duplex has been home to families for 140 years. Bring your family and your pet and enjoy 140 years of history. Quincy Quarters is close to Oakley Lindsay Center, Blessing Hospital and Quincy University, it is blocks away from South Park and just a couple minutes from downtown Quincy.

Superhost

The kitchen features a modern design with gray cabinetry and sleek countertops. An island with seating is positioned adjacent to a round dining table. Large appliances are visible, and a window allows natural light to illuminate the space, enhancing the kitchen's functionality.

Home in Palmyra

4.89 out of 5 average rating, 36 reviews

Charming Stay Close to Beau & Co

Welcome to Your Small Town Retreat: 2-BR House Near Beau & Company Escape to this cozy and conveniently located 2-bedroom, 1-bathroom house just moments away from the heart of town. Whether you're here for business or pleasure, this charming Airbnb offers comfort, style, and accessibility. The house features two inviting bedrooms, each thoughtfully decorated for a peaceful night's sleep.

Top guest favorite

A welcoming living area features two comfortable sofas arranged around a wooden coffee table. A stone accent wall hosts a flat-screen television, and framed artwork adorns the walls. A kitchenette is partially visible in the background, alongside a wall clock and air conditioning unit.

Guesthouse in Paris

4.98 out of 5 average rating, 140 reviews

Salt River Alpacas Guesthouse

Kick back and relax in this newly built guesthouse. Located on a peninsula on Mark Twain Lake, this guesthouse is surrounded by 130 acres of rolling pastures, plenty of woodlands, and the lake on three sides of the property. Whether you enjoy hiking, canoeing/kayaking, fishing, hunting, learning about our alpacas, or you just want a quiet place to relax, this property has it all!