Vacation rentals in Palmyra

Frogmore Cottage on 5-acre lake, Enjoy Nature!

PLEASE ENTER CORRECT NUMBER OF GUESTS WHEN BOOKING. Enjoy nature on this five-acre lake on 25 well-manicured acres. Fabulous sunsets! For a tiny house it has a spacious lower level with vaulted ceiling and upper bedroom loft. Wifi & smart TV. Nice warm heat and cool AC. Outdoor activity includes hammocks, swimming, boating (canoe, kayaks, john boat). For fishing we have boats, nets & fish-dressing station (bring poles & bait). About 13 miles from Palmyra and Monroe, nearest gas and groceries.

The Spring House!

Enjoy a stylish experience at this centrally-located 1890's farmhouse that has been completely transformed with all of the amenities you want and need. This convenient first floor apartment is located right across from one of Quincy's most iconic and favorite restaurant's, The Abbey! A fabulous space that features keyless entry, beautiful kitchen with quartz counter tops and stainless steel appliances, a wonderful onyx shower and comfortable beds with high end furnishings and lots of extras.

Cozy country 2-bedroom home with a view.

Make some memories at this unique and family-friendly place. Enjoy the view of horses grazing while sipping your morning coffee on the front porch. Drive to historic Hannibal, MO (11 miles). Book a guided farm tour with the owners and/or a riding lesson on one of their many rodeo horses. This house sleeps 6 with a king bed, queen bed, and couch fold-out queen bed. Need more room? (See the other listing for this option). The hostess is right next door to assist with any of your needs!

Cozy and Convenient Guesthouse on Family Farm!

Right on the edge of town, and only a quick trip to everything in town, the guesthouse on our family farm is the perfect stay. It's quaint and cozy, yet convenient to the highway, shopping, restaurants, and groceries. You will feel right at home, whether you're cozying up to watch a movie, sitting on the front porch watching the sun set, or cooking breakfast in our full kitchen. Welcome to your farm away from home! Close to the airport! Right off the interstate 2 minutes from Walmart

Genevieve’s Federal House

This home is a fully restored 1 story Federal house, which you will have full access to. It is located close to the Mark Twain Boyhood Home, and right off Broadway. The house comes furnished with seating, furniture, and 2 Roku televisions. There are two bedrooms, one bathroom, a dining room, living room, and a kitchen. The home has central air conditioning and heating, washer and dryer, dishwasher, and a beautiful clawfoot cast-iron tub with shower. There is off street parking.

Spacious Historic Two Story Home

Located on historic Palmyra Main Street, this home is only 12 minutes to the legendary home of Mark Twain -Hannibal, MO. Bring the whole family to this great place with lots of room for fun. This updated two story historic Victorian home is close to everything, making it easy to plan your visit. Enjoy a large covered front porch to relax. This home has the original refinished hardwood floors throughout. I love the unique hand crafted wood furniture in the dining and living room.

Laura’s Simply Charming Cottage

Simply Charming Cottage is located in the heart of Quincy. Brand newly updated and cozy with the character of an older home. An abundance of windows flood the home with natural light giving it a very uplifting feel. The home is the only one on the block allowing ample parking and a sense of privacy. Quaint brick courtyard privacy fenced in the rear yard. Just a short walk to Quincy University, Blessing Hospital Grocery Dining. Family operated locally. IL Licensed Broker Owned

Main Street Suite w River & Main St Views!

Located in the heart of Historic Downtown Hannibal. Bring back the nostalgia or start memories of your own by staying in this charming antique building, built in 1879. Newly renovated suite allows for modern amenities while still enjoying the Hallmark charm of the Main street and the birthplace of Mark Twain. Short walks to the Big Muddy Mississippi River, Lighthouse, Riverboat, shopping and restaurants. Take a short drive to the caves for the full Tom Sawyer experience.

J&J Hideaway

Welcome to J&J Hideaway! Relax in our charming 2-bedroom home, just blocks from Quincy University and minutes from Blessing Hospital, restaurants, and a supermarket. This cozy house features an updated kitchen and bathroom, newer flooring, and a spacious patio perfect for summer BBQs. Plus, enjoy an oversized 2-car garage (20x24) and plenty of parking. A comfortable, convenient stay awaits—your family will be close to everything in this centrally located home!

Eaton's Airbnb D

Enjoy a warm, pristine, and inviting atmosphere at our Airbnb, ideally situated in the heart of Quincy, IL. Located in a safe, family-friendly neighborhood, our Airbnb is operated by a local family and is just a four-block stroll from QU Stadium, with Quincy University also within close proximity. Blessing Hospital is a brief 5-minute drive away. Take advantage of our convenient off-street parking, featuring a dedicated spot for your vehicle. Let us host you!

Spacious King Suite | Fireplace • Full Kitchen

Welcome to our Spacious King Suite, a thoughtfully designed, private retreat perfect for couples, solo travelers, or extended stays. This beautifully styled suite combines historic charm with modern comfort — featuring a luxurious king bed, cozy fireplace, full kitchen, and inviting living area. Whether you’re visiting for a weekend getaway or settling in for a longer stay, this space is designed to feel calm, comfortable, and effortlessly livable.

QU Hawks Nest with parking and Wi-Fi W/D SmartTV

Centrally located in Quincy Illinois to Blessing Hospital, Quincy University and Quincy Medical Center. Just a short 20 Minute drive to Historical Hannibal MO, home of Mark Twain. Take a ride down the Mississippi on the Riverboat Cruise! This private 1 bedroom apartment will be a great fit for students, traveling medical professionals, visiting university families or just folks looking for a get a way.