House vacation rentals in Orangeburg County

4.95 out of 5 average rating, 82 reviews

Cozy, comfy, convenient, cottage!

We think you'll love this peaceful, family friendly cottage. For a price similar to a local hotel, you'll get a newly remodeled 2-bedroom house complete with kitchen and formal dining room located on fenced in lot 🐶 in quiet neighborhood. The master has a king bed with 400 count Egyptian cotton sheets and a bamboo mattress topper. The guest has a queen bed with a sensafoam mattress. There is a new 50” tv and high speed fiber WI-FI. There is also a breakfast bar with your favorite coffee.

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5.0 out of 5 average rating, 22 reviews

Renovated—Spotless Home—Quiet Area Near Food/HBCUs

Escape to this peaceful 2-acre retreat that features a lovely 5-acre pond in the backyard. Enjoy the serene waterfront views or melt away stress in the jetted bathtub. The spacious, modern farmhouse is located at the end of a cul-de-sac. The one-story renovated home offers comfortable rooms and amenities. Also close to places of interest: — 2-3 minute drive • Dining, groceries, shopping • Orangeburg Recreational Park — 8-10 minute drive • S. C. S. U. and C. U. • Orangeburg Country Club

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A spacious living area features a large blue sectional sofa adorned with patterned cushions. A light wooden coffee table sits on a soft area rug, complemented by a small potted plant. Natural light filters through the windows, creating a bright and welcoming environment.

5.0 out of 5 average rating, 152 reviews

The Grand Marshall

Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

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Superhost

The exterior of the house is framed by trees, featuring a wooden façade and a covered porch with a railing. The surrounding yard is grassy, providing a natural setting. A small staircase leads to the entrance, enhancing accessibility.

Home in Olar

4.95 out of 5 average rating, 186 reviews

The Pond House at Salkehatchie Farms

The Pond House is a secluded getaway in the woods with double glass doors throughout the house so you can enjoy nature, even while you are inside. It sits at the end of the winding drive through dogwoods in the spring, green trees in summer and colored leaves in autumn. There is a small pond on the edge of the property. Outdoor patios are a wonderful place to breathe in the early morning air, watch a sunset, or grill. There is plenty of room for walks and the property is yours to explore.

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4.97 out of 5 average rating, 91 reviews

A serene view of Lake Marion is captured, featuring calm waters reflecting blue skies and lush greenery. A wooden dock is visible on the left, surrounded by grass and trees, creating a tranquil natural setting.

Home in Eutawville

Heated Indoor Pool on Lake Marion with Dock

Lake Marion Lakefront on a private 2.5 acres. Two houses - 4500 sq. ft. of space, plenty of room for 14! Dock to fish off of or bring your fishing boat. Heated indoor pool and Margaritaville-themed bar. Firepit, pool table, games, and dining table for 14 people. Great spot for Family Gatherings or Friends' Getaway. Golf, fishing, fruit picking, and amazing country food restaurants - 25 min drive. 5% Discount Gov. Employees :) Parties over 14 ppl ++ fees apply, details discussed prior.

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4.94 out of 5 average rating, 186 reviews

Home in Summerton

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

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The exterior of a renovated Cape Cod home is visible, featuring a light-colored façade with dark trim. A brick chimney rises from the sloping roof. A front porch with decorative railing adds charm, while neat landscaping frames the property, enhancing its inviting presence.

4.92 out of 5 average rating, 49 reviews

Ron's Siesta Airbnb

A beautifully renovated Cape Cod, reminiscent of the late 1940's is located near restaurants, groceries, and the universities; some of which are in walking distance. While located on a main thoroughfare, the home exudes a quiet and peaceful atmosphere. There are two bedrooms, bath, kitchen, eating and dinning area. A warn place to feel welcomed and at home. Universities: SCSU walk 18 min 1.0mil; Claflin University walk 15min. 0.8 mil; The Village Center walk: 3min 0.2mil.

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4.96 out of 5 average rating, 204 reviews

An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.

Home in Santee

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

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4.99 out of 5 average rating, 132 reviews

A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.

Home in Summerton

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

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5.0 out of 5 average rating, 24 reviews

Furnished 3BR Near MUSC, SC State & Claflin

Relax in comfort at Stamford Haven Retreat! Enjoy a private fenced backyard with patio seating, a zero-gravity massage chair, and a fully stocked kitchen. Wake up to our Keurig coffee bar with coffee, teas, iced tea, creamers, sugar, and honey. Washer/dryer with detergent pods included. Minutes from SCSU, Claflin, MUSC, shopping, and dining—the perfect home away from home with hotel-style comforts and thoughtful amenities for every stay!

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Superhost

Home in Summerton

4.78 out of 5 average rating, 27 reviews

Lake Marion | Chill, Cruise, or Cast a Line for 8!

Wake up to quiet mornings, sip coffee by the water, cast a line, and let the day slow down. This Lake Marion home is all about relaxing, fishing, and unplugging with your favorite people. This is the perfect place to reset, recharge, and enjoy the simple things. No rush. No noise. Just lake life, done right. PS: this IS a fresh water lake in SC with a lot of wildlife, including alligators...swim, fish, and play at your own risk.

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