
Vacation rentals in O'Brien
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Top-rated vacation rentals in O'Brien
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Top guest favorite

Home in Live Oak
4.89 out of 5 average rating, 64 reviewsSunflower Studio Farm & Wellness Spa On Site
AlexanderRating, 5 stars2 days ago
This place was amazing. One of the best airbnbs we stayed at. We highly recommend visiting if you are on a road trip or even if you are just looking for a place to relax
Guest favorite

Home in Branford
5 out of 5 average rating, 12 reviewsThe Confluence Cabin
AshleyRating, 5 stars3 weeks ago
I can’t say enough positive things about this place. The location was perfect. My husband and I visited for a few days with our two dogs, and kayaked around the Santa Fe, and Ichetucknee river. The dock was perfect to launch the kayaks out of, and let our dogs watch the fish, and the pavilion over the river was great to relax in and watch boats pass by. The yard was beautiful, landscaped, and entirely fenced in for the dogs ( there was even a fence/gate to separate the upper deck from front door/front steps.) We will absolutely be back again as soon as we can.
Top guest favorite

Camper/RV in Fort White
4.96 out of 5 average rating, 26 reviewsIda's retreat
StevenRating, 5 stars6 days ago
Great stay, was very happy with the place. Fire pit and wood there for use. Plenty of towels and clean place.
Superhost

Home in Lake City
5 out of 5 average rating, 11 reviewsCozy Retreat, Open Backyard, in a quiet Cul De Sac
RyanRating, 5 stars1 month ago
Kimberly was very kind and responsive. Her place worked great for my work crew for the week. Would absolutely book this place again. Make sure to check out Ichetucknee springs while in the area you won’t be disappointed! Also XAPA has some of the best coffee I’ve ever had.
Top guest favorite

Cabin in Mayo
4.97 out of 5 average rating, 32 reviewsSuwannee River Hide Away Cabin
MichelRating, 5 stars2 weeks ago
The place was clean, well-equipped, and beautiful. We were looking for a relaxing environment, and this place is. The kayaks available on the property are a plus for enjoying the river. Recommended
Top guest favorite

Home in Lake City
4.96 out of 5 average rating, 47 reviewsCute & Cozy FL Home
MelindaRating, 5 stars3 days ago
This was our second time staying in Alyssa’s place. Her place was just as good as it was the first time we stayed there. Very clean house and just as described. We will definitely stay again when we are back in the area.
Top guest favorite

Camper/RV in Lake City
5 out of 5 average rating, 33 reviewsFaith and Love Farm Retreat
RuthRating, 5 starstoday
We loved our stay in this little RV on the farm! It was super clean upon our arrival and we were greeted by Janee who was very welcoming and kind. The hosts were very communicative and gave super clear instructions, so I was able to find my way there even in the pouring rain. We also enjoyed getting to see the farm animals every morning! Would definitely stay again if we find ourselves back in Lake City!
Top guest favorite

Home in Bell
4.87 out of 5 average rating, 93 reviewsSuwannee River Getaway
BlairRating, 5 stars2 weeks ago
Always a pleasure staying at Steve's place! It has everything I need when I'm in the area, and is conveniently located to many local springs and dive sites. The AC works great on the hot days, and the washer/dryer make it perfect for longer stays. Looking forward to my next visit!
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- Ginnie Springs
- Gilchrist Blue Springs State Park
- Ichetucknee Springs State Park
- Manatee Springs State Park
- Madison Blue Spring State Park
- Keaton Beach
- Florida Museum of Natural History
- Shired Island Trail Beach
- Depot Park
- Suwannee Country Club
- Ironwood Golf Course
- Horseshoe Beach Park
- Fanning Springs State Park
- Suwannee River State Park