Hotels in Missouri

Find and book unique hotels on Airbnb

Top-rated hotels in Missouri

Guests agree: these hotels are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1

Guest favorite

Hotel room in Hermann

Crown’s Cycle Suite 1837 Bar/Food Music Breakfast

Downtown, Seasonal Nightly Live Patio Music, Onsite Must See Underground Bar/Restaurant, Free Buffet Breakfast, $20 Personalized All Day Shuttle, Free Drink Tickets. Enjoy the Cycle Suite with Katy Trail & Bicycle Decor. 1 Queen Bed/1 Bath/TV/Cable/ WiFi/Coffee Maker/Coffee. Ideal for Katy Trail riders riding the trail/locked interior bike storage/charging. Right in the Historic District. Next Door to Shopping, Restaurants, and Bars. Guests Use the Hermann Crown Shuttle Onsite at $20 Daily.

LocationValueBathroom

4.94 out of 5 average rating, 17 reviews

Top guest favorite

A cozy king bedroom showcases a plush bed adorned with colorful pillows. Overhead, large decorative lanterns provide soft lighting. A blue armchair resides in one corner, complemented by a textured area rug. Natural light enters through a large window and double doors leading to a balcony.

Hotel room in Ironton

The King Suite at Pickle & Perk

Located on Main Street in the heart of The Valley. Tucked above our locally loved coffee bar, a cozy king suite perfect for solo travelers or couples looking for a quaint, bed-and-breakfast style escape. Featuring a plush king bedroom, a full private bathroom with a stand-up shower, and a kitchenette equipped for light bites and midnight snacks. A private entrance opens directly into our caged courtyard, giving you a quiet, off-the-street entrance and a peaceful nook to enjoy your morning brew.

ValueLocationQuiet

5.0 out of 5 average rating, 59 reviews

Top guest favorite

A comfortable bedroom features a queen bed with a light-colored quilt and decorative pillows. A wooden dresser and a mirror stand against one wall. Natural light enters through a nearby window, illuminating the warm tones of the furnishings.

Hotel room in Preston

Front Motel Room

You won’t want to leave this charming, one-of-a-kind place. Ample parking for trailers! We’re located 2.5 mi from the Weathered Wisdom barn, 10 mi from Pomme De Terre lake, 14 mi from Lucas Oil Speedway! Enjoy your own Motel room with outside entrance only, with a full private bath and queen bed.. The property is quiet and nestled in the woods.. We have 2 motel rooms and a bunkhouse available! Enjoy a morning cup of coffee on our deck! Look for the White Oaks signs!

FamilyValueAccuracy

5.0 out of 5 average rating, 62 reviews

Superhost

Hotel room in Eminence

White Family Cabin 1B

This Eminence hotel boasts one soothing bedroom with a full bed, perfect for a restful night. Guests enjoy a cool atmosphere thanks to air conditioning and heating that keeps the space comfortable year-round. The bathroom features a hair dryer, adding convenience to your stay. Whether you’re winding down after a day of exploring or simply relaxing indoors, this tremendous spot offers a peaceful retreat. Experience what Eminence has to offer with a stay at our hotel.

LocationQuietSleep quality

4.81 out of 5 average rating, 16 reviews

Guest favorite

Hotel room in Hermann

Nestle Inn - (2 Bedroom Suite King/Queen) Room 12

Nestle Inn is a charming hotel located in the heart of Hermann, MO. Steps from the town’s famous wineries, restaurants, and riverfront attractions. Easy access to the Katy Trail with ample bike storage. Whether you’re visiting for a romantic weekend, a wine‑country adventure, or a peaceful escape, or quick stop off the Katy Trail, our beautifully restored inn offers comfort, character, and true small‑town hospitality.

LocationCleanlinessHospitality

5.0 out of 5 average rating, 5 reviews

Superhost

Hotel room in Downtown Kansas City

Downtown Kansas City Stay + Restaurant. Bar. Gym.

Step into KC history at Hotel Savoy—where vintage tiles, tucked-away lounges, and downtown energy set the vibe. Just a short walk to the River Market and Power & Light, this boutique stay blends century-old charm with modern perks like free Wi-Fi and a 24/7 gym. Grab a drink in the legendary Savoy Lounge, then crash in style upstairs. Perfect for food crawls, concerts, or just soaking up KC like a local.

ValueFamilyPets

4.78 out of 5 average rating, 138 reviews

Superhost

The Governor's Suite features a four-poster bed elegantly framed against blue floral wallpaper. A light-colored blanket is neatly arranged atop the bed. A decorative mirror and a wooden side table complement the room, while a fireplace adds a cozy touch.

Hotel room in Ste. Genevieve

Governor's Suite at The Dr. Hertich House

Enjoy easy access to popular shops and restaurants from this charming place to stay. Step back in time and discover the enchanting history of the Dr. Hertich House with a cozy stay at The Hertich House Heritage Hotel in Ste. Genevieve, MO. The Governor's Suite welcomes guests with a blend of old-world charm and modern comforts, such as a private jacuzzi tub and romantic fireplace.

ValueLocationHot tub

4.87 out of 5 average rating, 77 reviews

Guest favorite

A spacious copper bathtub is showcased, featuring elegant detailing and handles on either side. A light blue towel is neatly draped over the edge, contrasting with the rich tones of the tub. Natural light illuminates the bathroom's warm color palette.

Hotel room in Washington

Meriwether's Room: Suite

A stylish space with a large bathroom that includes both a separate glass shower and a gorgeous copper tub. Among the largest of our four rooms, it would be perfect for a bridal suite or business stay. This room is located on the 2nd floor over our quaint wine bar. Just steps from our Historic downtown riverfront community with plenty of bars, restaurants, and shops to explore.

ValueLocationAmenities

4.85 out of 5 average rating, 149 reviews

Guest favorite

A bright seating area features large windows allowing ample natural light. A cozy sofa rests against the wall, accompanied by a wooden dining table surrounded by upholstered chairs. A painting of a natural landscape completes the aesthetic, adding a calming element to the space.

Hotel room in St. Charles Historic District

Calming, Chic Space w/ Natural Light- Owl Suite

The Owl Suite at the Divine Otter Hotel offers a stylish 1-bedroom escape, sleeping up to 2 guests. Enjoy upscale furnishings, a modern design, and a spacious full bathroom with plenty of natural light. Located in the heart of Historic Main Street Saint Charles, you’ll be steps away from shops, dining, and more. This impressive suite is the perfect blend of comfort and location!

LocationIndoor spacesComfort

4.76 out of 5 average rating, 42 reviews

Guest favorite

Hotel room in Westphalia

Cozy, Historic Boutique Hotel Room above Café

Experience the Inn’s history in the only room with its original 1930s layout. Featuring a queen bed, private bath, and balcony access, it’s perfect for relaxing with coffee overlooking Main Street — with our café just below. Please note: Guest rooms are accessible by stairs only. The property does not have an elevator.

LocationValueIndoor spaces

4.91 out of 5 average rating, 35 reviews

Top guest favorite

A spacious bedroom features a large bed with a quilted cover and decorative pillows. A green velvet couch sits nearby, complemented by a floor lamp. Natural light enters through a window framed by flowing curtains, while a mirror and artwork adorn the walls.

Hotel room in Blackwater

Cozy Coffee Shop Stay!

You won’t want to leave this charming, one-of-a-kind place. Located above an award winning coffee shop in beautiful, picturesque Blackwater, MO. This 1 bed, 1 bath rental is located in a historic building. This is an old building so it will have imperfections, but what it lacks in perfection, it makes up for in charm.

LocationValueCheck-in

4.97 out of 5 average rating, 128 reviews

Top guest favorite

Hotel room in Downtown Kansas City

Loft #205 - 2BR-1BA Loft Downtown KC in Historic B

2 Bedroom, 1 Bath Loft has been beautifully renovated with all new kitchens, bathrooms, furnishings etc. Located in the heart of downtown, blocks from Convention Center, Power & Light District, Sprint Center & free KC Streetcar that will take you from River Market to Crown Center and Union Station.

LocationFamilyTV

4.95 out of 5 average rating, 506 reviews